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Items: 12


Linaclotide, through activation of guanylate cyclase C, acts locally in the gastrointestinal tract to elicit enhanced intestinal secretion and transit.

Busby RW, Bryant AP, Bartolini WP, Cordero EA, Hannig G, Kessler MM, Mahajan-Miklos S, Pierce CM, Solinga RM, Sun LJ, Tobin JV, Kurtz CB, Currie MG.

Eur J Pharmacol. 2010 Dec 15;649(1-3):328-35. doi: 10.1016/j.ejphar.2010.09.019. Epub 2010 Sep 20.


Linaclotide is a potent and selective guanylate cyclase C agonist that elicits pharmacological effects locally in the gastrointestinal tract.

Bryant AP, Busby RW, Bartolini WP, Cordero EA, Hannig G, Kessler MM, Pierce CM, Solinga RM, Tobin JV, Mahajan-Miklos S, Cohen MB, Kurtz CB, Currie MG.

Life Sci. 2010 May 8;86(19-20):760-5. doi: 10.1016/j.lfs.2010.03.015. Epub 2010 Mar 20.


The Drosophila melanogaster toll pathway participates in resistance to infection by the gram-negative human pathogen Pseudomonas aeruginosa.

Lau GW, Goumnerov BC, Walendziewicz CL, Hewitson J, Xiao W, Mahajan-Miklos S, Tompkins RG, Perkins LA, Rahme LG.

Infect Immun. 2003 Jul;71(7):4059-66.


Differential roles of the Pseudomonas aeruginosa PA14 rpoN gene in pathogenicity in plants, nematodes, insects, and mice.

Hendrickson EL, Plotnikova J, Mahajan-Miklos S, Rahme LG, Ausubel FM.

J Bacteriol. 2001 Dec;183(24):7126-34.


Elucidating the molecular mechanisms of bacterial virulence using non-mammalian hosts.

Mahajan-Miklos S, Rahme LG, Ausubel FM.

Mol Microbiol. 2000 Sep;37(5):981-8. Review.


Plants and animals share functionally common bacterial virulence factors.

Rahme LG, Ausubel FM, Cao H, Drenkard E, Goumnerov BC, Lau GW, Mahajan-Miklos S, Plotnikova J, Tan MW, Tsongalis J, Walendziewicz CL, Tompkins RG.

Proc Natl Acad Sci U S A. 2000 Aug 1;97(16):8815-21. Review.


Drosophila quail, a villin-related protein, bundles actin filaments in apoptotic nurse cells.

Matova N, Mahajan-Miklos S, Mooseker MS, Cooley L.

Development. 1999 Dec;126(24):5645-57.


Killing of Caenorhabditis elegans by Pseudomonas aeruginosa used to model mammalian bacterial pathogenesis.

Tan MW, Mahajan-Miklos S, Ausubel FM.

Proc Natl Acad Sci U S A. 1999 Jan 19;96(2):715-20.


Drosophila fascin mutants are rescued by overexpression of the villin-like protein, quail.

Cant K, Knowles BA, Mahajan-Miklos S, Heintzelman M, Cooley L.

J Cell Sci. 1998 Jan;111 ( Pt 2):213-21.


Intercellular cytoplasm transport during Drosophila oogenesis.

Mahajan-Miklos S, Cooley L.

Dev Biol. 1994 Oct;165(2):336-51. Review. No abstract available.


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