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Items: 15

1.

NLRP3 Inflammasome Regulates Development of Systemic Inflammatory Response and Compensatory Anti-inflammatory Response Syndromes in Mice With Acute Pancreatitis.

Sendler M, van den Brandt C, Glaubitz J, Wilden A, Golchert J, Weiss FU, Homuth G, De Freitas Chama LL, Mishra N, Mahajan UM, Bossaller L, Völker U, Bröker BM, Mayerle J, Lerch MM.

Gastroenterology. 2019 Oct 5. pii: S0016-5085(19)41413-3. doi: 10.1053/j.gastro.2019.09.040. [Epub ahead of print]

2.

The impact of physiological stress conditions on protein structure and trypsin inhibition of serine protease inhibitor Kazal type 1 (SPINK1) and its N34S variant.

Buchholz I, Nagel F, Klein A, Wagh PR, Mahajan UM, Greinacher A, Lerch MM, Mayerle J, Delcea M.

Biochim Biophys Acta Proteins Proteom. 2019 Sep 13:140281. doi: 10.1016/j.bbapap.2019.140281. [Epub ahead of print]

3.

Early trypsin activation develops independently of autophagy in caerulein-induced pancreatitis in mice.

Malla SR, Krueger B, Wartmann T, Sendler M, Mahajan UM, Weiss FU, Thiel FG, De Boni C, Gorelick FS, Halangk W, Aghdassi AA, Reinheckel T, Gukovskaya AS, Lerch MM, Mayerle J.

Cell Mol Life Sci. 2019 Jul 30. doi: 10.1007/s00018-019-03254-7. [Epub ahead of print]

PMID:
31363815
4.

The effects of hepatic steatosis on thromboxane A2 induced portal hypertension.

Zhang J, Schewe J, Li H, Makeschin MC, Mahajan UM, Gerbes AL, Steib CJ.

Gastroenterol Hepatol. 2019 Nov;42(9):534-541. doi: 10.1016/j.gastrohep.2019.03.015. Epub 2019 Jul 17. English, Spanish.

PMID:
31326104
5.

Ring1b-dependent epigenetic remodelling is an essential prerequisite for pancreatic carcinogenesis.

Benitz S, Straub T, Mahajan UM, Mutter J, Czemmel S, Unruh T, Wingerath B, Deubler S, Fahr L, Cheng T, Nahnsen S, Bruns P, Kong B, Raulefs S, Ceyhan GO, Mayerle J, Steiger K, Esposito I, Kleeff J, Michalski CW, Regel I.

Gut. 2019 Nov;68(11):2007-2018. doi: 10.1136/gutjnl-2018-317208. Epub 2019 Apr 6.

PMID:
30954952
6.

Immune Cell and Stromal Signature Associated With Progression-Free Survival of Patients With Resected Pancreatic Ductal Adenocarcinoma.

Mahajan UM, Langhoff E, Goni E, Costello E, Greenhalf W, Halloran C, Ormanns S, Kruger S, Boeck S, Ribback S, Beyer G, Dombroswki F, Weiss FU, Neoptolemos JP, Werner J, D'Haese JG, Bazhin A, Peterhansl J, Pichlmeier S, Büchler MW, Kleeff J, Ganeh P, Sendler M, Palmer DH, Kohlmann T, Rad R, Regel I, Lerch MM, Mayerle J.

Gastroenterology. 2018 Nov;155(5):1625-1639.e2. doi: 10.1053/j.gastro.2018.08.009. Epub 2018 Aug 6.

PMID:
30092175
7.

[Pancreatic Cancer in the Year 2018 - Room for Precision Medicine?]

Simon O, Beyer G, Mahajan UM, Mayerle J.

Dtsch Med Wochenschr. 2018 Aug;143(15):1109-1112. doi: 10.1055/a-0542-4310. Epub 2018 Jul 30. German.

PMID:
30060283
8.

Reply.

Beyer G, Mahajan UM, Lerch MM, Mayerle J.

Gastroenterology. 2018 May;154(6):1853-1854. doi: 10.1053/j.gastro.2018.03.061. Epub 2018 Apr 3. No abstract available.

PMID:
29621520
9.

Cathepsin B-Mediated Activation of Trypsinogen in Endocytosing Macrophages Increases Severity of Pancreatitis in Mice.

Sendler M, Weiss FU, Golchert J, Homuth G, van den Brandt C, Mahajan UM, Partecke LI, Döring P, Gukovsky I, Gukovskaya AS, Wagh PR, Lerch MM, Mayerle J.

Gastroenterology. 2018 Feb;154(3):704-718.e10. doi: 10.1053/j.gastro.2017.10.018. Epub 2018 Jan 10.

10.

Development and Validation of a Chronic Pancreatitis Prognosis Score in 2 Independent Cohorts.

Beyer G, Mahajan UM, Budde C, Bulla TJ, Kohlmann T, Kuhlmann L, Schütte K, Aghdassi AA, Weber E, Weiss FU, Drewes AM, Olesen SS, Lerch MM, Mayerle J.

Gastroenterology. 2017 Dec;153(6):1544-1554.e2. doi: 10.1053/j.gastro.2017.08.073. Epub 2017 Sep 14.

PMID:
28918191
11.

Metabolic biomarker signature to differentiate pancreatic ductal adenocarcinoma from chronic pancreatitis.

Mayerle J, Kalthoff H, Reszka R, Kamlage B, Peter E, Schniewind B, González Maldonado S, Pilarsky C, Heidecke CD, Schatz P, Distler M, Scheiber JA, Mahajan UM, Weiss FU, Grützmann R, Lerch MM.

Gut. 2018 Jan;67(1):128-137. doi: 10.1136/gutjnl-2016-312432. Epub 2017 Jan 20. Erratum in: Gut. 2018 May;67(5):994.

12.

Effect of oral administration of AZD8309, a CXCR2 antagonist, on the severity of experimental pancreatitis.

Malla SR, Kärrman Mårdh C, Günther A, Mahajan UM, Sendler M, D'Haese J, Weiss FU, Lerch MM, Hansen MB, Mayerle J.

Pancreatology. 2016 Sep-Oct;16(5):761-9. doi: 10.1016/j.pan.2016.07.005. Epub 2016 Jul 14.

PMID:
27450968
13.

Tumour-specific delivery of siRNA-coupled superparamagnetic iron oxide nanoparticles, targeted against PLK1, stops progression of pancreatic cancer.

Mahajan UM, Teller S, Sendler M, Palankar R, van den Brandt C, Schwaiger T, Kühn JP, Ribback S, Glöckl G, Evert M, Weitschies W, Hosten N, Dombrowski F, Delcea M, Weiss FU, Lerch MM, Mayerle J.

Gut. 2016 Nov;65(11):1838-1849. doi: 10.1136/gutjnl-2016-311393. Epub 2016 May 12.

14.

Complement Component 5 Mediates Development of Fibrosis, via Activation of Stellate Cells, in 2 Mouse Models of Chronic Pancreatitis.

Sendler M, Beyer G, Mahajan UM, Kauschke V, Maertin S, Schurmann C, Homuth G, Völker U, Völzke H, Halangk W, Wartmann T, Weiss FU, Hegyi P, Lerch MM, Mayerle J.

Gastroenterology. 2015 Sep;149(3):765-76.e10. doi: 10.1053/j.gastro.2015.05.012. Epub 2015 May 19.

15.

Alteration in inflammatory/apoptotic pathway and histone modifications by nordihydroguaiaretic acid prevents acute pancreatitis in swiss albino mice.

Mahajan UM, Gupta C, Wagh PR, Karpe PA, Tikoo K.

Apoptosis. 2011 Nov;16(11):1138-49. doi: 10.1007/s10495-011-0643-8.

PMID:
21874356

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