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Items: 9

1.

Atherogenic lipid stress induces platelet hyperactivity through CD36-mediated hyposensitivity to prostacyclin-; the role of phosphodiesterase 3A.

Berger M, Raslan Z, Aburima A, Magwenzi S, Wraith KS, SPurgeon BEJ, Hindle MS, Law R, Febbraio M, Naseem KM.

Haematologica. 2019 Jul 9. pii: haematol.2018.213348. doi: 10.3324/haematol.2018.213348. [Epub ahead of print]

2.

The dietary flavonol quercetin ameliorates angiotensin II-induced redox signaling imbalance in a human umbilical vein endothelial cell model of endothelial dysfunction via ablation of p47phox expression.

Jones HS, Gordon A, Magwenzi SG, Naseem K, Atkin SL, Courts FL.

Mol Nutr Food Res. 2016 Apr;60(4):787-97. doi: 10.1002/mnfr.201500751. Epub 2016 Mar 1.

PMID:
26778209
3.

Targeting of type I protein kinase A to lipid rafts is required for platelet inhibition by the 3',5'-cyclic adenosine monophosphate-signaling pathway.

Raslan Z, Magwenzi S, Aburima A, Taskén K, Naseem KM.

J Thromb Haemost. 2015 Sep;13(9):1721-34. doi: 10.1111/jth.13042. Epub 2015 Aug 12.

4.

Oxidized LDL activates blood platelets through CD36/NOX2-mediated inhibition of the cGMP/protein kinase G signaling cascade.

Magwenzi S, Woodward C, Wraith KS, Aburima A, Raslan Z, Jones H, McNeil C, Wheatcroft S, Yuldasheva N, Febbriao M, Kearney M, Naseem KM.

Blood. 2015 Apr 23;125(17):2693-703. doi: 10.1182/blood-2014-05-574491. Epub 2015 Feb 20.

5.

Acute hypertriglyceridemia induces platelet hyperactivity that is not attenuated by insulin in polycystic ovary syndrome.

Aye MM, Kilpatrick ES, Aburima A, Wraith KS, Magwenzi S, Spurgeon B, Rigby AS, Sandeman D, Naseem KM, Atkin SL.

J Am Heart Assoc. 2014 Feb 28;3(1):e000706. doi: 10.1161/JAHA.113.000706.

6.

cAMP signaling regulates platelet myosin light chain (MLC) phosphorylation and shape change through targeting the RhoA-Rho kinase-MLC phosphatase signaling pathway.

Aburima A, Wraith KS, Raslan Z, Law R, Magwenzi S, Naseem KM.

Blood. 2013 Nov 14;122(20):3533-45. doi: 10.1182/blood-2013-03-487850. Epub 2013 Oct 7.

7.

Oxidized low-density lipoproteins induce rapid platelet activation and shape change through tyrosine kinase and Rho kinase-signaling pathways.

Wraith KS, Magwenzi S, Aburima A, Wen Y, Leake D, Naseem KM.

Blood. 2013 Jul 25;122(4):580-9. doi: 10.1182/blood-2013-04-491688. Epub 2013 May 22.

8.

Factor XIII supports platelet activation and enhances thrombus formation by matrix proteins under flow conditions.

Magwenzi SG, Ajjan RA, Standeven KF, Parapia LA, Naseem KM.

J Thromb Haemost. 2011 Apr;9(4):820-33. doi: 10.1111/j.1538-7836.2011.04234.x.

9.

Thrombospondin-1 induces platelet activation through CD36-dependent inhibition of the cAMP/protein kinase A signaling cascade.

Roberts W, Magwenzi S, Aburima A, Naseem KM.

Blood. 2010 Nov 18;116(20):4297-306. doi: 10.1182/blood-2010-01-265561. Epub 2010 Jul 27.

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