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Items: 1 to 50 of 99

1.

A Novel Zak Knockout Mouse with a Defective Ribotoxic Stress Response.

Jandhyala DM, Wong J, Mantis NJ, Magun BE, Leong JM, Thorpe CM.

Toxins (Basel). 2016 Sep 2;8(9). pii: E259. doi: 10.3390/toxins8090259.

2.

Lung inflammation caused by inhaled toxicants: a review.

Wong J, Magun BE, Wood LJ.

Int J Chron Obstruct Pulmon Dis. 2016 Jun 23;11:1391-401. doi: 10.2147/COPD.S106009. eCollection 2016. Review.

3.

Production of IL-1β by bone marrow-derived macrophages in response to chemotherapeutic drugs: synergistic effects of doxorubicin and vincristine.

Wong J, Tran LT, Magun EA, Magun BE, Wood LJ.

Cancer Biol Ther. 2014 Oct;15(10):1395-403. doi: 10.4161/cbt.29922. Epub 2014 Jul 21.

4.

Shiga toxin 2-induced intestinal pathology in infant rabbits is A-subunit dependent and responsive to the tyrosine kinase and potential ZAK inhibitor imatinib.

Stone SM, Thorpe CM, Ahluwalia A, Rogers AB, Obata F, Vozenilek A, Kolling GL, Kane AV, Magun BE, Jandhyala DM.

Front Cell Infect Microbiol. 2012 Nov 8;2:135. doi: 10.3389/fcimb.2012.00135. eCollection 2012.

5.

Small molecule kinase inhibitors block the ZAK-dependent inflammatory effects of doxorubicin.

Wong J, Smith LB, Magun EA, Engstrom T, Kelley-Howard K, Jandhyala DM, Thorpe CM, Magun BE, Wood LJ.

Cancer Biol Ther. 2013 Jan;14(1):56-63. doi: 10.4161/cbt.22628. Epub 2012 Oct 31.

6.

Suppression of ribosomal function triggers innate immune signaling through activation of the NLRP3 inflammasome.

Vyleta ML, Wong J, Magun BE.

PLoS One. 2012;7(5):e36044. doi: 10.1371/journal.pone.0036044. Epub 2012 May 14.

7.

Doxorubicin and daunorubicin induce processing and release of interleukin-1β through activation of the NLRP3 inflammasome.

Sauter KA, Wood LJ, Wong J, Iordanov M, Magun BE.

Cancer Biol Ther. 2011 Jun 15;11(12):1008-16. Epub 2011 Jun 15.

8.

ZAK is required for doxorubicin, a novel ribotoxic stressor, to induce SAPK activation and apoptosis in HaCaT cells.

Sauter KA, Magun EA, Iordanov MS, Magun BE.

Cancer Biol Ther. 2010 Aug 1;10(3):258-66. Epub 2010 Aug 13.

9.

Pulmonary inflammation triggered by ricin toxin requires macrophages and IL-1 signaling.

Lindauer ML, Wong J, Iwakura Y, Magun BE.

J Immunol. 2009 Jul 15;183(2):1419-26. doi: 10.4049/jimmunol.0901119. Epub 2009 Jun 26.

10.

Mouse model of hemolytic-uremic syndrome caused by endotoxin-free Shiga toxin 2 (Stx2) and protection from lethal outcome by anti-Stx2 antibody.

Sauter KA, Melton-Celsa AR, Larkin K, Troxell ML, O'Brien AD, Magun BE.

Infect Immun. 2008 Oct;76(10):4469-78. doi: 10.1128/IAI.00592-08. Epub 2008 Aug 11.

11.

Fas ligand-induced proinflammatory transcriptional responses in reconstructed human epidermis. Recruitment of the epidermal growth factor receptor and activation of MAP kinases.

Farley SM, Purdy DE, Ryabinina OP, Schneider P, Magun BE, Iordanov MS.

J Biol Chem. 2008 Jan 11;283(2):919-28. Epub 2007 Oct 31.

12.

Proinflammatory responses of human airway cells to ricin involve stress-activated protein kinases and NF-kappaB.

Wong J, Korcheva V, Jacoby DB, Magun BE.

Am J Physiol Lung Cell Mol Physiol. 2007 Dec;293(6):L1385-94. Epub 2007 Sep 14.

13.

Fas ligand elicits a caspase-independent proinflammatory response in human keratinocytes: implications for dermatitis.

Farley SM, Dotson AD, Purdy DE, Sundholm AJ, Schneider P, Magun BE, Iordanov MS.

J Invest Dermatol. 2006 Nov;126(11):2438-51. Epub 2006 Jul 20.

14.
15.

Cell death-induced activation of epidermal growth factor receptor in keratinocytes: implications for restricting epidermal damage in dermatitis.

Iordanov MS, Sundholm AJ, Simpson EL, Hanifin JM, Ryabinina OP, Choi RJ, Korcheva VB, Schneider P, Magun BE.

J Invest Dermatol. 2005 Jul;125(1):134-42.

16.

Recruitment of TRADD, FADD, and caspase 8 to double-stranded RNA-triggered death inducing signaling complexes (dsRNA-DISCs).

Iordanov MS, Kirsch JD, Ryabinina OP, Wong J, Spitz PN, Korcheva VB, Thorburn A, Magun BE.

Apoptosis. 2005 Jan;10(1):167-76.

PMID:
15711932
17.

Two mechanisms of caspase 9 processing in double-stranded RNA- and virus-triggered apoptosis.

Iordanov MS, Ryabinina OP, Schneider P, Magun BE.

Apoptosis. 2005 Jan;10(1):153-66.

PMID:
15711931
19.

Specifically targeting the CD22 receptor of human B-cell lymphomas with RNA damaging agents.

Newton DL, Hansen HJ, Liu H, Ruby D, Iordanov MS, Magun BE, Goldenberg DM, Rybak SM.

Crit Rev Oncol Hematol. 2001 Jul-Aug;39(1-2):79-86. Review.

PMID:
11418304
20.

Differential requirement for the stress-activated protein kinase/c-Jun NH(2)-terminal kinase in RNAdamage-induced apoptosis in primary and in immortalized fibroblasts.

Iordanov MS, Wong J, Newton DL, Rybak SM, Bright RK, Flavell RA, Davis RJ, Magun BE.

Mol Cell Biol Res Commun. 2000 Aug;4(2):122-8.

PMID:
11170843
22.
23.
25.

Ultraviolet radiation triggers the ribotoxic stress response in mammalian cells.

Iordanov MS, Pribnow D, Magun JL, Dinh TH, Pearson JA, Magun BE.

J Biol Chem. 1998 Jun 19;273(25):15794-803.

28.

Complex interactions with direct repeats of a mitogen-responsive VL30 enhancer.

Pribnow D, Chen SL, Zhang Y, Magun BE.

Biochim Biophys Acta. 1996 Jun 3;1307(1):55-65.

PMID:
8652668
30.

Characterization of a unique enhancer element responsive to cyclic adenosine 3',5'-monophosphate and elevated calcium.

Rodland KD, Pribnow D, Lenormand P, Chen SL, Magun BE.

Mol Endocrinol. 1993 Jun;7(6):787-96.

PMID:
8395655
31.

Endothelin induces transcription of fos/jun family genes: a prominent role for calcium ion.

Pribnow D, Muldoon LL, Fajardo M, Theodor L, Chen LY, Magun BE.

Mol Endocrinol. 1992 Jul;6(7):1003-12.

PMID:
1508217
33.

Regulation of transin/stromelysin and VL30 gene expression by intracellular calcium.

Rodland KD, Lenormand P, Muldoon LL, Magun BE.

J Invest Dermatol. 1992 Jun;98(6 Suppl):12S-16S. Review.

34.

The role of C-Fos in growth factor regulation of stromelysin/transin gene expression.

Kerr LD, Magun BE, Matrisian LM.

Matrix Suppl. 1992;1:176-83.

PMID:
1480019
35.

Stimulation of Ca2+ influx by endothelin-1 is subject to negative feedback by elevated intracellular Ca2+.

Muldoon LL, Enslen H, Rodland KD, Magun BE.

Am J Physiol. 1991 Jun;260(6 Pt 1):C1273-81.

PMID:
1905483
36.

Regulation of intracellular Ca2+ and gene expression by endothelin-1.

Rodland KD, Muldoon LL, Magun BE.

J Cardiovasc Pharmacol. 1991;17 Suppl 7:S89-95.

PMID:
1725441
37.
38.
40.

Cellular mechanisms of TGF-beta action.

Rodland KD, Muldoon LL, Magun BE.

J Invest Dermatol. 1990 Jun;94(6 Suppl):33S-40S. Review.

PMID:
2191053
41.
42.

NGF induction of the gene encoding the protease transin accompanies neuronal differentiation in PC12 cells.

Machida CM, Rodland KD, Matrisian L, Magun BE, Ciment G.

Neuron. 1989 Jun;2(6):1587-96.

PMID:
2560648
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48.

Effect of maturation on gastrointestinal absorption of epidermal growth factor in rats.

Thornburg W, Rao RK, Matrisian LM, Magun BE, Koldovský O.

Am J Physiol. 1987 Jul;253(1 Pt 1):G68-71.

PMID:
3496799

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