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A surface-in gradient of thalamic damage evolves in pediatric multiple sclerosis.

Fadda G, Brown RA, Magliozzi R, Aubert-Broche B, O'Mahony J, Shinohara RT, Banwell B, Marrie RA, Yeh EA, Collins DL, Arnold DL, Bar-Or A; Canadian Pediatric Demyelinating Disease Network.

Ann Neurol. 2019 Mar;85(3):340-351. doi: 10.1002/ana.25429. Epub 2019 Feb 20.


TNF-alpha and metalloproteases as key players in melanoma cells aggressiveness.

Rossi S, Cordella M, Tabolacci C, Nassa G, D'Arcangelo D, Senatore C, Pagnotto P, Magliozzi R, Salvati A, Weisz A, Facchiano A, Facchiano F.

J Exp Clin Cancer Res. 2018 Dec 28;37(1):326. doi: 10.1186/s13046-018-0982-1.


Effect of glatiramer acetate on cerebral grey matter pathology in patients with relapsing-remitting multiple sclerosis.

Crescenzo F, Marastoni D, Zuco C, Pitteri M, Magliozzi R, Monaco S, Calabrese M.

Mult Scler Relat Disord. 2019 Jan;27:305-311. doi: 10.1016/j.msard.2018.11.009. Epub 2018 Nov 12.


Meningeal inflammation and cortical demyelination in acute multiple sclerosis.

Bevan RJ, Evans R, Griffiths L, Watkins LM, Rees MI, Magliozzi R, Allen I, McDonnell G, Kee R, Naughton M, Fitzgerald DC, Reynolds R, Neal JW, Howell OW.

Ann Neurol. 2018 Dec;84(6):829-842. doi: 10.1002/ana.25365. Epub 2018 Nov 30.


MRI of cortical lesions and its use in studying their role in MS pathogenesis and disease course.

Magliozzi R, Reynolds R, Calabrese M.

Brain Pathol. 2018 Sep;28(5):735-742. doi: 10.1111/bpa.12642.


Neonatal corticosterone mitigates autoimmune neuropsychiatric disorders associated with streptococcus in mice.

Macrì S, Spinello C, Widomska J, Magliozzi R, Poelmans G, Invernizzi RW, Creti R, Roessner V, Bartolini E, Margarit I, Glennon J, Laviola G.

Sci Rep. 2018 Jul 5;8(1):10188. doi: 10.1038/s41598-018-28372-3.


Serum and cerebrospinal neurofilament light chain levels in patients with acquired peripheral neuropathies.

Mariotto S, Farinazzo A, Magliozzi R, Alberti D, Monaco S, Ferrari S.

J Peripher Nerv Syst. 2018 Sep;23(3):174-177. doi: 10.1111/jns.12279. Epub 2018 Jul 24.


Inheritance of the Golgi Apparatus and Cytokinesis Are Controlled by Degradation of GBF1.

Magliozzi R, Carrero ZI, Low TY, Yuniati L, Valdes-Quezada C, Kruiswijk F, van Wijk K, Heck AJR, Jackson CL, Guardavaccaro D.

Cell Rep. 2018 Jun 12;23(11):3381-3391.e4. doi: 10.1016/j.celrep.2018.05.031.


The cortical damage, early relapses, and onset of the progressive phase in multiple sclerosis.

Scalfari A, Romualdi C, Nicholas RS, Mattoscio M, Magliozzi R, Morra A, Monaco S, Muraro PA, Calabrese M.

Neurology. 2018 Jun 12;90(24):e2107-e2118. doi: 10.1212/WNL.0000000000005685. Epub 2018 May 16.


Inflammatory intrathecal profiles and cortical damage in multiple sclerosis.

Magliozzi R, Howell OW, Nicholas R, Cruciani C, Castellaro M, Romualdi C, Rossi S, Pitteri M, Benedetti MD, Gajofatto A, Pizzini FB, Montemezzi S, Rasia S, Capra R, Bertoldo A, Facchiano F, Monaco S, Reynolds R, Calabrese M.

Ann Neurol. 2018 Apr;83(4):739-755. doi: 10.1002/ana.25197.


Potential neuroprotective effect of Fingolimod in multiple sclerosis and its association with clinical variables.

Pitteri M, Magliozzi R, Bajrami A, Camera V, Calabrese M.

Expert Opin Pharmacother. 2018 Mar;19(4):387-395. doi: 10.1080/14656566.2018.1434143. Epub 2018 Feb 3. Review.


Dimethyl fumarate: a possible exit strategy from natalizumab treatment in patients with multiple sclerosis at risk for severe adverse events.

Calabrese M, Pitteri M, Farina G, Bajrami A, Castellaro M, Magliozzi R, Monaco S.

J Neurol Neurosurg Psychiatry. 2017 Dec;88(12):1073-1078. doi: 10.1136/jnnp-2017-316236. Epub 2017 Aug 26.


Programmed death 1 is highly expressed on CD8+ CD57+ T cells in patients with stable multiple sclerosis and inhibits their cytotoxic response to Epstein-Barr virus.

Cencioni MT, Magliozzi R, Nicholas R, Ali R, Malik O, Reynolds R, Borsellino G, Battistini L, Muraro PA.

Immunology. 2017 Dec;152(4):660-676. doi: 10.1111/imm.12808. Epub 2017 Sep 21.


Heterogeneity of Cortical Lesion Susceptibility Mapping in Multiple Sclerosis.

Castellaro M, Magliozzi R, Palombit A, Pitteri M, Silvestri E, Camera V, Montemezzi S, Pizzini FB, Bertoldo A, Reynolds R, Monaco S, Calabrese M.

AJNR Am J Neuroradiol. 2017 Jun;38(6):1087-1095. doi: 10.3174/ajnr.A5150. Epub 2017 Apr 13.


Increased cortical lesion load and intrathecal inflammation is associated with oligoclonal bands in multiple sclerosis patients: a combined CSF and MRI study.

Farina G, Magliozzi R, Pitteri M, Reynolds R, Rossi S, Gajofatto A, Benedetti MD, Facchiano F, Monaco S, Calabrese M.

J Neuroinflammation. 2017 Feb 21;14(1):40. doi: 10.1186/s12974-017-0812-y.


Cognitive impairment predicts disability progression and cortical thinning in MS: An 8-year study.

Pitteri M, Romualdi C, Magliozzi R, Monaco S, Calabrese M.

Mult Scler. 2017 May;23(6):848-854. doi: 10.1177/1352458516665496. Epub 2016 Aug 15.


Epilepsy in multiple sclerosis: The role of temporal lobe damage.

Calabrese M, Castellaro M, Bertoldo A, De Luca A, Pizzini FB, Ricciardi GK, Pitteri M, Zimatore S, Magliozzi R, Benedetti MD, Manganotti P, Montemezzi S, Reynolds R, Gajofatto A, Monaco S.

Mult Scler. 2017 Mar;23(3):473-482. doi: 10.1177/1352458516651502. Epub 2016 Jul 11.


Mice repeatedly exposed to Group-A β-Haemolytic Streptococcus show perseverative behaviors, impaired sensorimotor gating, and immune activation in rostral diencephalon.

Macrì S, Ceci C, Onori MP, Invernizzi RW, Bartolini E, Altabella L, Canese R, Imperi M, Orefici G, Creti R, Margarit I, Magliozzi R, Laviola G.

Sci Rep. 2015 Aug 25;5:13257. doi: 10.1038/srep13257.


Regional Distribution and Evolution of Gray Matter Damage in Different Populations of Multiple Sclerosis Patients.

Calabrese M, Reynolds R, Magliozzi R, Castellaro M, Morra A, Scalfari A, Farina G, Romualdi C, Gajofatto A, Pitteri M, Benedetti MD, Monaco S.

PLoS One. 2015 Aug 12;10(8):e0135428. doi: 10.1371/journal.pone.0135428. eCollection 2015.


Datasets from an interaction proteomics screen for substrates of the SCF(βTrCP) ubiquitin ligase.

Magliozzi R, Peng M, Mohammed S, Guardavaccaro D, Heck AJ, Low TY.

Data Brief. 2015 Jun 10;4:229-34. doi: 10.1016/j.dib.2015.05.003. eCollection 2015 Sep.


Temporal lobe cortical pathology and inhibitory GABA interneuron cell loss are associated with seizures in multiple sclerosis.

Nicholas R, Magliozzi R, Campbell G, Mahad D, Reynolds R.

Mult Scler. 2016 Jan;22(1):25-35. doi: 10.1177/1352458515579445. Epub 2015 Apr 28.


Exploring the origins of grey matter damage in multiple sclerosis.

Calabrese M, Magliozzi R, Ciccarelli O, Geurts JJ, Reynolds R, Martin R.

Nat Rev Neurosci. 2015 Mar;16(3):147-58. doi: 10.1038/nrn3900. Review.


Nodal signaling range is regulated by proprotein convertase-mediated maturation.

Tessadori F, Noël ES, Rens EG, Magliozzi R, Evers-van Gogh IJ, Guardavaccaro D, Merks RM, Bakkers J.

Dev Cell. 2015 Mar 9;32(5):631-9. doi: 10.1016/j.devcel.2014.12.014. Epub 2015 Feb 12.


A systems-wide screen identifies substrates of the SCFβTrCP ubiquitin ligase.

Low TY, Peng M, Magliozzi R, Mohammed S, Guardavaccaro D, Heck AJ.

Sci Signal. 2014 Dec 16;7(356):rs8. doi: 10.1126/scisignal.2005882.


USP17- and SCFβTrCP--regulated degradation of DEC1 controls the DNA damage response.

Kim J, D'Annibale S, Magliozzi R, Low TY, Jansen P, Shaltiel IA, Mohammed S, Heck AJ, Medema RH, Guardavaccaro D.

Mol Cell Biol. 2014 Nov 15;34(22):4177-85. doi: 10.1128/MCB.00530-14. Epub 2014 Sep 8.


Degradation of Tiam1 by casein kinase 1 and the SCFβTrCP ubiquitin ligase controls the duration of mTOR-S6K signaling.

Magliozzi R, Kim J, Low TY, Heck AJ, Guardavaccaro D.

J Biol Chem. 2014 Oct 3;289(40):27400-9. doi: 10.1074/jbc.M114.575571. Epub 2014 Aug 14.


Proteasome-dependent degradation of transcription factor activating enhancer-binding protein 4 (TFAP4) controls mitotic division.

D'Annibale S, Kim J, Magliozzi R, Low TY, Mohammed S, Heck AJ, Guardavaccaro D.

J Biol Chem. 2014 Mar 14;289(11):7730-7. doi: 10.1074/jbc.M114.549535. Epub 2014 Feb 5.


Control of epithelial cell migration and invasion by the IKKβ- and CK1α-mediated degradation of RAPGEF2.

Magliozzi R, Low TY, Weijts BG, Cheng T, Spanjaard E, Mohammed S, van Veen A, Ovaa H, de Rooij J, Zwartkruis FJ, Bos JL, de Bruin A, Heck AJ, Guardavaccaro D.

Dev Cell. 2013 Dec 9;27(5):574-85. doi: 10.1016/j.devcel.2013.10.023. Epub 2013 Nov 27.


Cortical grey matter demyelination can be induced by elevated pro-inflammatory cytokines in the subarachnoid space of MOG-immunized rats.

Gardner C, Magliozzi R, Durrenberger PF, Howell OW, Rundle J, Reynolds R.

Brain. 2013 Dec;136(Pt 12):3596-608. doi: 10.1093/brain/awt279. Epub 2013 Oct 30.


B-cell enrichment and Epstein-Barr virus infection in inflammatory cortical lesions in secondary progressive multiple sclerosis.

Magliozzi R, Serafini B, Rosicarelli B, Chiappetta G, Veroni C, Reynolds R, Aloisi F.

J Neuropathol Exp Neurol. 2013 Jan;72(1):29-41. doi: 10.1097/NEN.0b013e31827bfc62.


Unraveling the ubiquitin-regulated signaling networks by mass spectrometry-based proteomics.

Low TY, Magliozzi R, Guardavaccaro D, Heck AJ.

Proteomics. 2013 Feb;13(3-4):526-37. doi: 10.1002/pmic.201200244. Epub 2012 Nov 26. Review.


Meningeal inflammation plays a role in the pathology of primary progressive multiple sclerosis.

Choi SR, Howell OW, Carassiti D, Magliozzi R, Gveric D, Muraro PA, Nicholas R, Roncaroli F, Reynolds R.

Brain. 2012 Oct;135(Pt 10):2925-37. doi: 10.1093/brain/aws189. Epub 2012 Aug 20.


Selection of novel reference genes for use in the human central nervous system: a BrainNet Europe Study.

Durrenberger PF, Fernando FS, Magliozzi R, Kashefi SN, Bonnert TP, Ferrer I, Seilhean D, Nait-Oumesmar B, Schmitt A, Gebicke-Haerter PJ, Falkai P, Grünblatt E, Palkovits M, Parchi P, Capellari S, Arzberger T, Kretzschmar H, Roncaroli F, Dexter DT, Reynolds R.

Acta Neuropathol. 2012 Dec;124(6):893-903. doi: 10.1007/s00401-012-1027-z. Epub 2012 Aug 5.


Coupled activation and degradation of eEF2K regulates protein synthesis in response to genotoxic stress.

Kruiswijk F, Yuniati L, Magliozzi R, Low TY, Lim R, Bolder R, Mohammed S, Proud CG, Heck AJ, Pagano M, Guardavaccaro D.

Sci Signal. 2012 Jun 5;5(227):ra40. doi: 10.1126/scisignal.2002718.


Inhibition of soluble tumour necrosis factor is therapeutic in experimental autoimmune encephalomyelitis and promotes axon preservation and remyelination.

Brambilla R, Ashbaugh JJ, Magliozzi R, Dellarole A, Karmally S, Szymkowski DE, Bethea JR.

Brain. 2011 Sep;134(Pt 9):2736-54. doi: 10.1093/brain/awr199.


Meningeal inflammation is widespread and linked to cortical pathology in multiple sclerosis.

Howell OW, Reeves CA, Nicholas R, Carassiti D, Radotra B, Gentleman SM, Serafini B, Aloisi F, Roncaroli F, Magliozzi R, Reynolds R.

Brain. 2011 Sep;134(Pt 9):2755-71. doi: 10.1093/brain/awr182. Epub 2011 Aug 11.


A Gradient of neuronal loss and meningeal inflammation in multiple sclerosis.

Magliozzi R, Howell OW, Reeves C, Roncaroli F, Nicholas R, Serafini B, Aloisi F, Reynolds R.

Ann Neurol. 2010 Oct;68(4):477-93. doi: 10.1002/ana.22230.


Detection of Epstein-Barr virus and B-cell follicles in the multiple sclerosis brain: what you find depends on how and where you look.

Aloisi F, Serafini B, Magliozzi R, Howell OW, Reynolds R.

Brain. 2010 Dec;133(Pt 12):e157. doi: 10.1093/brain/awq223. Epub 2010 Aug 25. No abstract available.


Epstein-Barr virus latent infection and BAFF expression in B cells in the multiple sclerosis brain: implications for viral persistence and intrathecal B-cell activation.

Serafini B, Severa M, Columba-Cabezas S, Rosicarelli B, Veroni C, Chiappetta G, Magliozzi R, Reynolds R, Coccia EM, Aloisi F.

J Neuropathol Exp Neurol. 2010 Jul;69(7):677-93. doi: 10.1097/NEN.0b013e3181e332ec.


P2Y12 receptor protein in cortical gray matter lesions in multiple sclerosis.

Amadio S, Montilli C, Magliozzi R, Bernardi G, Reynolds R, Volonté C.

Cereb Cortex. 2010 Jun;20(6):1263-73. doi: 10.1093/cercor/bhp193. Epub 2009 Sep 26.


Isolation and analyses of enriched populations of male mouse germ cells by sedimentation velocity: the centrifugal elutriation.

Barchi M, Geremia R, Magliozzi R, Bianchi E.

Methods Mol Biol. 2009;558:299-321. doi: 10.1007/978-1-60761-103-5_18. Review.


Expression of TWEAK and its receptor Fn14 in the multiple sclerosis brain: implications for inflammatory tissue injury.

Serafini B, Magliozzi R, Rosicarelli B, Reynolds R, Zheng TS, Aloisi F.

J Neuropathol Exp Neurol. 2008 Dec;67(12):1137-48. doi: 10.1097/NEN.0b013e31818dab90.


Lymphoid chemokines in chronic neuroinflammation.

Aloisi F, Columba-Cabezas S, Franciotta D, Rosicarelli B, Magliozzi R, Reynolds R, Ambrosini E, Coccia E, Salvetti M, Serafini B.

J Neuroimmunol. 2008 Jul 31;198(1-2):106-12. doi: 10.1016/j.jneuroim.2008.04.025. Epub 2008 Jun 9. Review.


Dysregulated Epstein-Barr virus infection in the multiple sclerosis brain.

Serafini B, Rosicarelli B, Franciotta D, Magliozzi R, Reynolds R, Cinque P, Andreoni L, Trivedi P, Salvetti M, Faggioni A, Aloisi F.

J Exp Med. 2007 Nov 26;204(12):2899-912. Epub 2007 Nov 5.


Meningeal B-cell follicles in secondary progressive multiple sclerosis associate with early onset of disease and severe cortical pathology.

Magliozzi R, Howell O, Vora A, Serafini B, Nicholas R, Puopolo M, Reynolds R, Aloisi F.

Brain. 2007 Apr;130(Pt 4):1089-104.


Suppression of established experimental autoimmune encephalomyelitis and formation of meningeal lymphoid follicles by lymphotoxin beta receptor-Ig fusion protein.

Columba-Cabezas S, Griguoli M, Rosicarelli B, Magliozzi R, Ria F, Serafini B, Aloisi F.

J Neuroimmunol. 2006 Oct;179(1-2):76-86. Epub 2006 Jul 25.


Dendritic cells in multiple sclerosis lesions: maturation stage, myelin uptake, and interaction with proliferating T cells.

Serafini B, Rosicarelli B, Magliozzi R, Stigliano E, Capello E, Mancardi GL, Aloisi F.

J Neuropathol Exp Neurol. 2006 Feb;65(2):124-41.


Detection of ectopic B-cell follicles with germinal centers in the meninges of patients with secondary progressive multiple sclerosis.

Serafini B, Rosicarelli B, Magliozzi R, Stigliano E, Aloisi F.

Brain Pathol. 2004 Apr;14(2):164-74.


Effects of the plasticiser DEHP on lung of newborn rats: catalase immunocytochemistry and morphometric analysis.

Magliozzi R, Nardacci R, Scarsella G, Di Carlo V, Stefanini S.

Histochem Cell Biol. 2003 Jul;120(1):41-9. Epub 2003 Jun 11.


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