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Items: 19

1.

More than just hormones: H295R cells as predictors of reproductive toxicity.

Maglich JM, Kuhn M, Chapin RE, Pletcher MT.

Reprod Toxicol. 2014 Jun;45:77-86. doi: 10.1016/j.reprotox.2013.12.009. Epub 2014 Jan 13.

2.

Structure guided design of 5-arylindazole glucocorticoid receptor agonists and antagonists.

Yates CM, Brown PJ, Stewart EL, Patten C, Austin RJ, Holt JA, Maglich JM, Angell DC, Sasse RZ, Taylor SJ, Uings IJ, Trump RP.

J Med Chem. 2010 Jun 10;53(11):4531-44. doi: 10.1021/jm100447c.

PMID:
20469868
3.

The relative activity of "function sparing" HIV-1 entry inhibitors on viral entry and CCR5 internalization: is allosteric functional selectivity a valuable therapeutic property?

Muniz-Medina VM, Jones S, Maglich JM, Galardi C, Hollingsworth RE, Kazmierski WM, Ferris RG, Edelstein MP, Chiswell KE, Kenakin TP.

Mol Pharmacol. 2009 Mar;75(3):490-501. doi: 10.1124/mol.108.052555. Epub 2008 Dec 8.

PMID:
19064629
4.

The nuclear receptor CAR (NR1I3) regulates serum triglyceride levels under conditions of metabolic stress.

Maglich JM, Lobe DC, Moore JT.

J Lipid Res. 2009 Mar;50(3):439-45. doi: 10.1194/jlr.M800226-JLR200. Epub 2008 Oct 21.

5.

Paralogous vitamin D receptors in teleosts: transition of nuclear receptor function.

Howarth DL, Law SH, Barnes B, Hall JM, Hinton DE, Moore L, Maglich JM, Moore JT, Kullman SW.

Endocrinology. 2008 May;149(5):2411-22. doi: 10.1210/en.2007-1256. Epub 2008 Feb 7. Erratum in: Endocrinology. 2008 Oct;149(10):5315.

6.

The phytoestrogen coumestrol is a naturally occurring antagonist of the human pregnane X receptor.

Wang H, Li H, Moore LB, Johnson MD, Maglich JM, Goodwin B, Ittoop OR, Wisely B, Creech K, Parks DJ, Collins JL, Willson TM, Kalpana GV, Venkatesh M, Xie W, Cho SY, Roboz J, Redinbo M, Moore JT, Mani S.

Mol Endocrinol. 2008 Apr;22(4):838-57. Epub 2007 Dec 20.

7.

The nuclear receptor CAR is a regulator of thyroid hormone metabolism during caloric restriction.

Maglich JM, Watson J, McMillen PJ, Goodwin B, Willson TM, Moore JT.

J Biol Chem. 2004 May 7;279(19):19832-8. Epub 2004 Mar 5.

8.

Beyond the human genome: examples of nuclear receptor analysis in model organisms and potential for drug discovery.

Maglich JM, Sluder AE, Willson TM, Moore JT.

Am J Pharmacogenomics. 2003;3(5):345-53. Review.

PMID:
14575522
9.

The first completed genome sequence from a teleost fish (Fugu rubripes) adds significant diversity to the nuclear receptor superfamily.

Maglich JM, Caravella JA, Lambert MH, Willson TM, Moore JT, Ramamurthy L.

Nucleic Acids Res. 2003 Jul 15;31(14):4051-8.

10.

Induction of cytochrome P450 3A by paclitaxel in mice: pivotal role of the nuclear xenobiotic receptor, pregnane X receptor.

Nallani SC, Goodwin B, Maglich JM, Buckley DJ, Buckley AR, Desai PB.

Drug Metab Dispos. 2003 May;31(5):681-4.

PMID:
12695359
11.

Identification of a novel human constitutive androstane receptor (CAR) agonist and its use in the identification of CAR target genes.

Maglich JM, Parks DJ, Moore LB, Collins JL, Goodwin B, Billin AN, Stoltz CA, Kliewer SA, Lambert MH, Willson TM, Moore JT.

J Biol Chem. 2003 May 9;278(19):17277-83. Epub 2003 Feb 27.

12.

2.1 A crystal structure of human PXR in complex with the St. John's wort compound hyperforin.

Watkins RE, Maglich JM, Moore LB, Wisely GB, Noble SM, Davis-Searles PR, Lambert MH, Kliewer SA, Redinbo MR.

Biochemistry. 2003 Feb 18;42(6):1430-8.

PMID:
12578355
13.

Functional and structural comparison of PXR and CAR.

Moore JT, Moore LB, Maglich JM, Kliewer SA.

Biochim Biophys Acta. 2003 Feb 17;1619(3):235-8. Review.

PMID:
12573482
14.

Nuclear pregnane x receptor and constitutive androstane receptor regulate overlapping but distinct sets of genes involved in xenobiotic detoxification.

Maglich JM, Stoltz CM, Goodwin B, Hawkins-Brown D, Moore JT, Kliewer SA.

Mol Pharmacol. 2002 Sep;62(3):638-46.

PMID:
12181440
15.

Pregnane X receptor (PXR), constitutive androstane receptor (CAR), and benzoate X receptor (BXR) define three pharmacologically distinct classes of nuclear receptors.

Moore LB, Maglich JM, McKee DD, Wisely B, Willson TM, Kliewer SA, Lambert MH, Moore JT.

Mol Endocrinol. 2002 May;16(5):977-86.

PMID:
11981033
16.

Liver X receptor (LXR) regulation of the LXRalpha gene in human macrophages.

Whitney KD, Watson MA, Goodwin B, Galardi CM, Maglich JM, Wilson JG, Willson TM, Collins JL, Kliewer SA.

J Biol Chem. 2001 Nov 23;276(47):43509-15. Epub 2001 Aug 23.

17.

Comparison of complete nuclear receptor sets from the human, Caenorhabditis elegans and Drosophila genomes.

Maglich JM, Sluder A, Guan X, Shi Y, McKee DD, Carrick K, Kamdar K, Willson TM, Moore JT.

Genome Biol. 2001;2(8):RESEARCH0029. Epub 2001 Jul 24.

18.

IL-1 beta increases type 1 inositol trisphosphate receptor expression and IL-6 secretory capacity in osteoblastic cell cultures.

Bradford PG, Maglich JM, Kirkwood KL.

Mol Cell Biol Res Commun. 2000 Feb;3(2):73-5.

PMID:
10775502
19.

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