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Items: 16

1.

Usp9x Promotes Survival in Human Pancreatic Cancer and Its Inhibition Suppresses Pancreatic Ductal Adenocarcinoma In Vivo Tumor Growth.

Pal A, Dziubinski M, Di Magliano MP, Simeone DM, Owens S, Thomas D, Peterson L, Potu H, Talpaz M, Donato NJ.

Neoplasia. 2018 Feb;20(2):152-164. doi: 10.1016/j.neo.2017.11.007. Epub 2017 Dec 14.

2.

Mitogen-activated Protein Kinase Kinase Activity Maintains Acinar-to-Ductal Metaplasia and Is Required for Organ Regeneration in Pancreatitis.

Halbrook CJ, Wen HJ, Ruggeri JM, Takeuchi KK, Zhang Y, di Magliano MP, Crawford HC.

Cell Mol Gastroenterol Hepatol. 2017 Jan;3(1):99-118. doi: 10.1016/j.jcmgh.2016.09.009.

3.

ER stress protein AGR2 precedes and is involved in the regulation of pancreatic cancer initiation.

Dumartin L, Alrawashdeh W, Trabulo SM, Radon TP, Steiger K, Feakins RM, di Magliano MP, Heeschen C, Esposito I, Lemoine NR, Crnogorac-Jurcevic T.

Oncogene. 2017 Jun 1;36(22):3094-3103. doi: 10.1038/onc.2016.459. Epub 2016 Dec 12.

4.

Mesenchymal Stem Cells Promote Pancreatic Tumor Growth by Inducing Alternative Polarization of Macrophages.

Mathew E, Brannon AL, Del Vecchio A, Garcia PE, Penny MK, Kane KT, Vinta A, Buckanovich RJ, di Magliano MP.

Neoplasia. 2016 Mar;18(3):142-51. doi: 10.1016/j.neo.2016.01.005.

5.

Invasive mouse gastric adenocarcinomas arising from Lgr5+ stem cells are dependent on crosstalk between the Hedgehog/GLI2 and mTOR pathways.

Syu LJ, Zhao X, Zhang Y, Grachtchouk M, Demitrack E, Ermilov A, Wilbert DM, Zheng X, Kaatz A, Greenson JK, Gumucio DL, Merchant JL, di Magliano MP, Samuelson LC, Dlugosz AA.

Oncotarget. 2016 Mar 1;7(9):10255-70. doi: 10.18632/oncotarget.7182.

6.

Human carcinoma-associated mesenchymal stem cells promote ovarian cancer chemotherapy resistance via a BMP4/HH signaling loop.

Coffman LG, Choi YJ, McLean K, Allen BL, di Magliano MP, Buckanovich RJ.

Oncotarget. 2016 Feb 9;7(6):6916-32. doi: 10.18632/oncotarget.6870.

7.

CD44 regulates pancreatic cancer invasion through MT1-MMP.

Jiang W, Zhang Y, Kane KT, Collins MA, Simeone DM, di Magliano MP, Nguyen KT.

Mol Cancer Res. 2015 Jan;13(1):9-15. doi: 10.1158/1541-7786.MCR-14-0076. Epub 2015 Jan 7.

8.

The transcription factor GLI1 modulates the inflammatory response during pancreatic tissue remodeling.

Mathew E, Collins MA, Fernandez-Barrena MG, Holtz AM, Yan W, Hogan JO, Tata Z, Allen BL, Fernandez-Zapico ME, di Magliano MP.

J Biol Chem. 2014 Oct 3;289(40):27727-43. doi: 10.1074/jbc.M114.556563. Epub 2014 Aug 7.

9.

CD4+ T lymphocyte ablation prevents pancreatic carcinogenesis in mice.

Zhang Y, Yan W, Mathew E, Bednar F, Wan S, Collins MA, Evans RA, Welling TH, Vonderheide RH, di Magliano MP.

Cancer Immunol Res. 2014 May;2(5):423-35. doi: 10.1158/2326-6066.CIR-14-0016-T. Epub 2014 Feb 11.

10.

Interleukin-6 is required for pancreatic cancer progression by promoting MAPK signaling activation and oxidative stress resistance.

Zhang Y, Yan W, Collins MA, Bednar F, Rakshit S, Zetter BR, Stanger BZ, Chung I, Rhim AD, di Magliano MP.

Cancer Res. 2013 Oct 15;73(20):6359-74. doi: 10.1158/0008-5472.CAN-13-1558-T. Epub 2013 Oct 4.

11.

Deciphering the role of stroma in pancreatic cancer.

Waghray M, Yalamanchili M, di Magliano MP, Simeone DM.

Curr Opin Gastroenterol. 2013 Sep;29(5):537-43. doi: 10.1097/MOG.0b013e328363affe. Review.

12.

Roles for KRAS in pancreatic tumor development and progression.

di Magliano MP, Logsdon CD.

Gastroenterology. 2013 Jun;144(6):1220-9. doi: 10.1053/j.gastro.2013.01.071. Review.

13.

Metastatic pancreatic cancer is dependent on oncogenic Kras in mice.

Collins MA, Brisset JC, Zhang Y, Bednar F, Pierre J, Heist KA, Galbán CJ, Galbán S, di Magliano MP.

PLoS One. 2012;7(12):e49707. doi: 10.1371/journal.pone.0049707. Epub 2012 Dec 3.

14.

New frontiers in pancreatic cancer research.

Khan GN, di Magliano MP, Simeone DM.

Surg Oncol Clin N Am. 2010 Apr;19(2):431-51. doi: 10.1016/j.soc.2009.11.010.

PMID:
20159524
15.

Hedgehog is an early and late mediator of pancreatic cancer tumorigenesis.

Thayer SP, di Magliano MP, Heiser PW, Nielsen CM, Roberts DJ, Lauwers GY, Qi YP, Gysin S, Fernández-del Castillo C, Yajnik V, Antoniu B, McMahon M, Warshaw AL, Hebrok M.

Nature. 2003 Oct 23;425(6960):851-6. Epub 2003 Sep 14.

16.

The activation and maintenance of Pax2 expression at the mid-hindbrain boundary is controlled by separate enhancers.

Pfeffer PL, Payer B, Reim G, di Magliano MP, Busslinger M.

Development. 2002 Jan;129(2):307-18.

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