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Items: 1 to 50 of 278

1.

L-Lactate Regulates the Expression of Synaptic Plasticity and Neuroprotection Genes in Cortical Neurons: A Transcriptome Analysis.

Margineanu MB, Mahmood H, Fiumelli H, Magistretti PJ.

Front Mol Neurosci. 2018 Oct 10;11:375. doi: 10.3389/fnmol.2018.00375. eCollection 2018.

2.

A Process for Digitizing and Simulating Biologically Realistic Oligocellular Networks Demonstrated for the Neuro-Glio-Vascular Ensemble.

Coggan JS, Calì C, Keller D, Agus M, Boges D, Abdellah M, Kare K, Lehväslaiho H, Eilemann S, Jolivet RB, Hadwiger M, Markram H, Schürmann F, Magistretti PJ.

Front Neurosci. 2018 Sep 25;12:664. doi: 10.3389/fnins.2018.00664. eCollection 2018.

3.

Dual action of L-Lactate on the activity of NR2B-containing NMDA receptors: from potentiation to neuroprotection.

Jourdain P, Rothenfusser K, Ben-Adiba C, Allaman I, Marquet P, Magistretti PJ.

Sci Rep. 2018 Sep 7;8(1):13472. doi: 10.1038/s41598-018-31534-y.

4.

Norepinephrine stimulates glycogenolysis in astrocytes to fuel neurons with lactate.

Coggan JS, Keller D, Calì C, Lehväslaiho H, Markram H, Schürmann F, Magistretti PJ.

PLoS Comput Biol. 2018 Aug 30;14(8):e1006392. doi: 10.1371/journal.pcbi.1006392. eCollection 2018 Aug.

5.

Hypertonic Lactate to Improve Cerebral Perfusion and Glucose Availability After Acute Brain Injury.

Carteron L, Solari D, Patet C, Quintard H, Miroz JP, Bloch J, Daniel RT, Hirt L, Eckert P, Magistretti PJ, Oddo M.

Crit Care Med. 2018 Oct;46(10):1649-1655. doi: 10.1097/CCM.0000000000003274.

PMID:
29923931
6.

Impact of MCT1 Haploinsufficiency on the Mouse Retina.

Peachey NS, Yu M, Han JYS, Lengacher S, Magistretti PJ, Pellerin L, Philp NJ.

Adv Exp Med Biol. 2018;1074:375-380. doi: 10.1007/978-3-319-75402-4_46.

PMID:
29721966
7.

Lactate in the brain: from metabolic end-product to signalling molecule.

Magistretti PJ, Allaman I.

Nat Rev Neurosci. 2018 Apr;19(4):235-249. doi: 10.1038/nrn.2018.19. Epub 2018 Mar 8. Review.

PMID:
29515192
8.

Hypocretin/orexin deficiency decreases cocaine abuse liability.

Steiner N, Rossetti C, Sakurai T, Yanagisawa M, de Lecea L, Magistretti PJ, Halfon O, Boutrel B.

Neuropharmacology. 2018 May 1;133:395-403. doi: 10.1016/j.neuropharm.2018.02.010. Epub 2018 Feb 15.

PMID:
29454841
9.

Inadequate brain glycogen or sleep increases spreading depression susceptibility.

Kilic K, Karatas H, Dönmez-Demir B, Eren-Kocak E, Gursoy-Ozdemir Y, Can A, Petit JM, Magistretti PJ, Dalkara T.

Ann Neurol. 2018 Jan;83(1):61-73. doi: 10.1002/ana.25122.

PMID:
29244233
10.

Gender-specific alteration of energy balance and circadian locomotor activity in the Crtc1 knockout mouse model of depression.

Rossetti C, Sciarra D, Petit JM, Eap CB, Halfon O, Magistretti PJ, Boutrel B, Cardinaux JR.

Transl Psychiatry. 2017 Dec 8;7(12):1269. doi: 10.1038/s41398-017-0023-4.

11.

A preclinical model for identifying rats at risk of alcohol use disorder.

Jadhav KS, Magistretti PJ, Halfon O, Augsburger M, Boutrel B.

Sci Rep. 2017 Aug 25;7(1):9454. doi: 10.1038/s41598-017-09801-1.

12.

A Historical Review of Diachrony and Semantic Dimensions of Trace in Neurosciences and Lacanian Psychoanalysis.

Escobar C, Ansermet F, Magistretti PJ.

Front Psychol. 2017 Jun 23;8:734. doi: 10.3389/fpsyg.2017.00734. eCollection 2017. Review.

13.

Gathering by the Red Sea highlights links between environment and epigenetics.

Li M, Borrelli E, Magistretti PJ, Izpisua Belmonte JC, Sassone-Corsi P, Orlando V.

Nat Struct Mol Biol. 2017 Jun 6;24(6):491-493. doi: 10.1038/nsmb.3422. No abstract available.

PMID:
28586330
14.

Peripheral administration of lactate produces antidepressant-like effects.

Carrard A, Elsayed M, Margineanu M, Boury-Jamot B, Fragnière L, Meylan EM, Petit JM, Fiumelli H, Magistretti PJ, Martin JL.

Mol Psychiatry. 2018 Feb;23(2):488. doi: 10.1038/mp.2016.237. Epub 2016 Dec 6.

15.

A Motion Capture Study to Measure the Feeling of Synchrony in Romantic Couples and in Professional Musicians.

Preissmann D, Charbonnier C, Chagué S, Antonietti JP, Llobera J, Ansermet F, Magistretti PJ.

Front Psychol. 2016 Oct 27;7:1673. eCollection 2016.

16.

Peripheral administration of lactate produces antidepressant-like effects.

Carrard A, Elsayed M, Margineanu M, Boury-Jamot B, Fragnière L, Meylan EM, Petit JM, Fiumelli H, Magistretti PJ, Martin JL.

Mol Psychiatry. 2018 Feb;23(2):392-399. doi: 10.1038/mp.2016.179. Epub 2016 Oct 18. Erratum in: Mol Psychiatry. 2018 Feb;23 (2):488.

17.

Lactate release from astrocytes to neurons contributes to cocaine memory formation.

Boury-Jamot B, Halfon O, Magistretti PJ, Boutrel B.

Bioessays. 2016 Dec;38(12):1266-1273. doi: 10.1002/bies.201600118. Epub 2016 Oct 4. Review.

PMID:
27699812
18.

Protein targeting to glycogen is a master regulator of glycogen synthesis in astrocytes.

Ruchti E, Roach PJ, DePaoli-Roach AA, Magistretti PJ, Allaman I.

IBRO Rep. 2016 Oct 4;1:46-53. doi: 10.1016/j.ibror.2016.10.002. eCollection 2016 Dec.

19.

Involvement of the agmatinergic system in the depressive-like phenotype of the Crtc1 knockout mouse model of depression.

Meylan EM, Breuillaud L, Seredenina T, Magistretti PJ, Halfon O, Luthi-Carter R, Cardinaux JR.

Transl Psychiatry. 2016 Jul 12;6(7):e852. doi: 10.1038/tp.2016.116.

20.

Astrocytic β2-adrenergic receptors mediate hippocampal long-term memory consolidation.

Gao V, Suzuki A, Magistretti PJ, Lengacher S, Pollonini G, Steinman MQ, Alberini CM.

Proc Natl Acad Sci U S A. 2016 Jul 26;113(30):8526-31. doi: 10.1073/pnas.1605063113. Epub 2016 Jul 8.

21.

Imaging brain aerobic glycolysis as a marker of synaptic plasticity.

Magistretti PJ.

Proc Natl Acad Sci U S A. 2016 Jun 28;113(26):7015-6. doi: 10.1073/pnas.1607423113. Epub 2016 Jun 17. No abstract available.

22.

A Role for Lactate in the Consolidation of Drug-Related Associative Memories.

Boutrel B, Magistretti PJ.

Biol Psychiatry. 2016 Jun 1;79(11):875-7. doi: 10.1016/j.biopsych.2016.04.010. No abstract available.

PMID:
27198521
23.

Glutamate Cysteine Ligase-Modulatory Subunit Knockout Mouse Shows Normal Insulin Sensitivity but Reduced Liver Glycogen Storage.

Lavoie S, Steullet P, Kulak A, Preitner F, Do KQ, Magistretti PJ.

Front Physiol. 2016 Apr 21;7:142. doi: 10.3389/fphys.2016.00142. eCollection 2016.

24.

Sleep fragmentation alters brain energy metabolism without modifying hippocampal electrophysiological response to novelty exposure.

Baud MO, Parafita J, Nguyen A, Magistretti PJ, Petit JM.

J Sleep Res. 2016 Oct;25(5):583-590. doi: 10.1111/jsr.12419. Epub 2016 May 3.

25.

Sodium signaling and astrocyte energy metabolism.

Chatton JY, Magistretti PJ, Barros LF.

Glia. 2016 Oct;64(10):1667-76. doi: 10.1002/glia.22971. Epub 2016 Mar 29. Review.

26.

The HDAC inhibitor SAHA improves depressive-like behavior of CRTC1-deficient mice: Possible relevance for treatment-resistant depression.

Meylan EM, Halfon O, Magistretti PJ, Cardinaux JR.

Neuropharmacology. 2016 Aug;107:111-121. doi: 10.1016/j.neuropharm.2016.03.012. Epub 2016 Mar 9.

27.

L-Lactate protects neurons against excitotoxicity: implication of an ATP-mediated signaling cascade.

Jourdain P, Allaman I, Rothenfusser K, Fiumelli H, Marquet P, Magistretti PJ.

Sci Rep. 2016 Feb 19;6:21250. doi: 10.1038/srep21250.

28.

The Subjective Sensation of Synchrony: An Experimental Study.

Llobera J, Charbonnier C, Chagué S, Preissmann D, Antonietti JP, Ansermet F, Magistretti PJ.

PLoS One. 2016 Feb 12;11(2):e0147008. doi: 10.1371/journal.pone.0147008. eCollection 2016.

29.

A New Outlook on Mental Illnesses: Glial Involvement Beyond the Glue.

Elsayed M, Magistretti PJ.

Front Cell Neurosci. 2015 Dec 16;9:468. doi: 10.3389/fncel.2015.00468. eCollection 2015. Review.

30.

Regulation of neuron-astrocyte metabolic coupling across the sleep-wake cycle.

Petit JM, Magistretti PJ.

Neuroscience. 2016 May 26;323:135-56. doi: 10.1016/j.neuroscience.2015.12.007. Epub 2015 Dec 17. Review.

31.

In Vivo Evidence for a Lactate Gradient from Astrocytes to Neurons.

Mächler P, Wyss MT, Elsayed M, Stobart J, Gutierrez R, von Faber-Castell A, Kaelin V, Zuend M, San Martín A, Romero-Gómez I, Baeza-Lehnert F, Lengacher S, Schneider BL, Aebischer P, Magistretti PJ, Barros LF, Weber B.

Cell Metab. 2016 Jan 12;23(1):94-102. doi: 10.1016/j.cmet.2015.10.010. Epub 2015 Nov 19.

32.

Learning-Induced Gene Expression in the Hippocampus Reveals a Role of Neuron -Astrocyte Metabolic Coupling in Long Term Memory.

Tadi M, Allaman I, Lengacher S, Grenningloh G, Magistretti PJ.

PLoS One. 2015 Oct 29;10(10):e0141568. doi: 10.1371/journal.pone.0141568. eCollection 2015.

33.

Disrupting astrocyte-neuron lactate transfer persistently reduces conditioned responses to cocaine.

Boury-Jamot B, Carrard A, Martin JL, Halfon O, Magistretti PJ, Boutrel B.

Mol Psychiatry. 2016 Aug;21(8):1070-6. doi: 10.1038/mp.2015.157. Epub 2015 Oct 27.

34.

Goals in Nutrition Science 2015-2020.

Allison DB, Bassaganya-Riera J, Burlingame B, Brown AW, le Coutre J, Dickson SL, van Eden W, Garssen J, Hontecillas R, Khoo CS, Knorr D, Kussmann M, Magistretti PJ, Mehta T, Meule A, Rychlik M, Vögele C.

Front Nutr. 2015 Sep 8;2:26. doi: 10.3389/fnut.2015.00026. eCollection 2015. No abstract available.

35.

Improvement of Neuroenergetics by Hypertonic Lactate Therapy in Patients with Traumatic Brain Injury Is Dependent on Baseline Cerebral Lactate/Pyruvate Ratio.

Quintard H, Patet C, Zerlauth JB, Suys T, Bouzat P, Pellerin L, Meuli R, Magistretti PJ, Oddo M.

J Neurotrauma. 2016 Apr 1;33(7):681-7. doi: 10.1089/neu.2015.4057. Epub 2015 Dec 15.

36.

Complex regulation of CREB-binding protein by homeodomain-interacting protein kinase 2.

Kovács KA, Steinmann M, Halfon O, Magistretti PJ, Cardinaux JR.

Cell Signal. 2015 Nov;27(11):2252-60. doi: 10.1016/j.cellsig.2015.08.001. Epub 2015 Aug 4.

PMID:
26247811
37.

Three-dimensional immersive virtual reality for studying cellular compartments in 3D models from EM preparations of neural tissues.

Calì C, Baghabra J, Boges DJ, Holst GR, Kreshuk A, Hamprecht FA, Srinivasan M, Lehväslaiho H, Magistretti PJ.

J Comp Neurol. 2016 Jan 1;524(1):23-38. doi: 10.1002/cne.23852. Epub 2015 Aug 11.

38.

Astrocytes: New Targets for the Treatment of Neurodegenerative Diseases.

Finsterwald C, Magistretti PJ, Lengacher S.

Curr Pharm Des. 2015;21(25):3570-81. Review.

PMID:
26166612
39.

Review of quantitative phase-digital holographic microscopy: promising novel imaging technique to resolve neuronal network activity and identify cellular biomarkers of psychiatric disorders.

Marquet P, Depeursinge C, Magistretti PJ.

Neurophotonics. 2014 Oct;1(2):020901. doi: 10.1117/1.NPh.1.2.020901. Epub 2014 Sep 22. Review.

40.

Embodied memory: unconscious smiling modulates emotional evaluation of episodic memories.

Arminjon M, Preissmann D, Chmetz F, Duraku A, Ansermet F, Magistretti PJ.

Front Psychol. 2015 May 26;6:650. doi: 10.3389/fpsyg.2015.00650. eCollection 2015.

41.

A cellular perspective on brain energy metabolism and functional imaging.

Magistretti PJ, Allaman I.

Neuron. 2015 May 20;86(4):883-901. doi: 10.1016/j.neuron.2015.03.035. Review.

42.

Metabolic gene expression changes in astrocytes in Multiple Sclerosis cerebral cortex are indicative of immune-mediated signaling.

Zeis T, Allaman I, Gentner M, Schroder K, Tschopp J, Magistretti PJ, Schaeren-Wiemers N.

Brain Behav Immun. 2015 Aug;48:313-25. doi: 10.1016/j.bbi.2015.04.013. Epub 2015 Apr 30.

43.

Neuroenergetic Response to Prolonged Cerebral Glucose Depletion after Severe Brain Injury and the Role of Lactate.

Patet C, Quintard H, Suys T, Bloch J, Daniel RT, Pellerin L, Magistretti PJ, Oddo M.

J Neurotrauma. 2015 Oct 15;32(20):1560-6. doi: 10.1089/neu.2014.3781. Epub 2015 May 26.

PMID:
25790152
44.

Channel-mediated lactate release by K⁺-stimulated astrocytes.

Sotelo-Hitschfeld T, Niemeyer MI, Mächler P, Ruminot I, Lerchundi R, Wyss MT, Stobart J, Fernández-Moncada I, Valdebenito R, Garrido-Gerter P, Contreras-Baeza Y, Schneider BL, Aebischer P, Lengacher S, San Martín A, Le Douce J, Bonvento G, Magistretti PJ, Sepúlveda FV, Weber B, Barros LF.

J Neurosci. 2015 Mar 11;35(10):4168-78. doi: 10.1523/JNEUROSCI.5036-14.2015.

45.

Multi-timescale modeling of activity-dependent metabolic coupling in the neuron-glia-vasculature ensemble.

Jolivet R, Coggan JS, Allaman I, Magistretti PJ.

PLoS Comput Biol. 2015 Feb 26;11(2):e1004036. doi: 10.1371/journal.pcbi.1004036. eCollection 2015 Feb.

46.

Methylglyoxal, the dark side of glycolysis.

Allaman I, Bélanger M, Magistretti PJ.

Front Neurosci. 2015 Feb 9;9:23. doi: 10.3389/fnins.2015.00023. eCollection 2015. Review.

47.

Alzheimer's disease: the amyloid hypothesis and the Inverse Warburg effect.

Demetrius LA, Magistretti PJ, Pellerin L.

Front Physiol. 2015 Jan 14;5:522. doi: 10.3389/fphys.2014.00522. eCollection 2014.

48.

Deficiency in monocarboxylate transporter 1 (MCT1) in mice delays regeneration of peripheral nerves following sciatic nerve crush.

Morrison BM, Tsingalia A, Vidensky S, Lee Y, Jin L, Farah MH, Lengacher S, Magistretti PJ, Pellerin L, Rothstein JD.

Exp Neurol. 2015 Jan;263:325-38. doi: 10.1016/j.expneurol.2014.10.018. Epub 2014 Oct 29.

49.

Glycogen metabolism and the homeostatic regulation of sleep.

Petit JM, Burlet-Godinot S, Magistretti PJ, Allaman I.

Metab Brain Dis. 2015 Feb;30(1):263-79. doi: 10.1007/s11011-014-9629-x. Epub 2014 Nov 16. Review.

50.

Sustained sleep fragmentation induces sleep homeostasis in mice.

Baud MO, Magistretti PJ, Petit JM.

Sleep. 2015 Apr 1;38(4):567-79. doi: 10.5665/sleep.4572.

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