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Items: 1 to 50 of 355

1.

Ultrastructural Evidence for a Role of Astrocytes and Glycogen-Derived Lactate in Learning-Dependent Synaptic Stabilization.

Vezzoli E, Calì C, De Roo M, Ponzoni L, Sogne E, Gagnon N, Francolini M, Braida D, Sala M, Muller D, Falqui A, Magistretti PJ.

Cereb Cortex. 2019 Dec 6. pii: bhz226. doi: 10.1093/cercor/bhz226. [Epub ahead of print]

PMID:
31807747
2.

Lactate measurement by neurochemical profiling in the dorsolateral prefrontal cortex at 7T: accuracy, precision, and relaxation times.

Dehghani M, Do KQ, Magistretti P, Xin L.

Magn Reson Med. 2019 Nov 14. doi: 10.1002/mrm.28066. [Epub ahead of print]

PMID:
31729080
3.

A Method for 3D Reconstruction and Virtual Reality Analysis of Glial and Neuronal Cells.

Calì C, Kare K, Agus M, Veloz Castillo MF, Boges D, Hadwiger M, Magistretti P.

J Vis Exp. 2019 Sep 28;(151). doi: 10.3791/59444.

PMID:
31609327
4.

3D cellular reconstruction of cortical glia and parenchymal morphometric analysis from Serial Block-Face Electron Microscopy of juvenile rat.

Calì C, Agus M, Kare K, Boges DJ, Lehväslaiho H, Hadwiger M, Magistretti PJ.

Prog Neurobiol. 2019 Dec;183:101696. doi: 10.1016/j.pneurobio.2019.101696. Epub 2019 Sep 21.

5.

Lactate and pyruvate promote oxidative stress resistance through hormetic ROS signaling.

Tauffenberger A, Fiumelli H, Almustafa S, Magistretti PJ.

Cell Death Dis. 2019 Sep 10;10(9):653. doi: 10.1038/s41419-019-1877-6.

6.

Gangliosides: Treatment Avenues in Neurodegenerative Disease.

Magistretti PJ, Geisler FH, Schneider JS, Li PA, Fiumelli H, Sipione S.

Front Neurol. 2019 Aug 6;10:859. doi: 10.3389/fneur.2019.00859. eCollection 2019. Review.

7.

Precise in vivo genome editing via single homology arm donor mediated intron-targeting gene integration for genetic disease correction.

Suzuki K, Yamamoto M, Hernandez-Benitez R, Li Z, Wei C, Soligalla RD, Aizawa E, Hatanaka F, Kurita M, Reddy P, Ocampo A, Hishida T, Sakurai M, Nemeth AN, Nuñez Delicado E, Campistol JM, Magistretti P, Guillen P, Rodriguez Esteban C, Gong J, Yuan Y, Gu Y, Liu GH, López-Otín C, Wu J, Zhang K, Izpisua Belmonte JC.

Cell Res. 2019 Oct;29(10):804-819. doi: 10.1038/s41422-019-0213-0. Epub 2019 Aug 23.

PMID:
31444470
8.

Genome-wide association study identifies eight risk loci and implicates metabo-psychiatric origins for anorexia nervosa.

Watson HJ, Yilmaz Z, Thornton LM, Hübel C, Coleman JRI, Gaspar HA, Bryois J, Hinney A, Leppä VM, Mattheisen M, Medland SE, Ripke S, Yao S, Giusti-Rodríguez P; Anorexia Nervosa Genetics Initiative, Hanscombe KB, Purves KL; Eating Disorders Working Group of the Psychiatric Genomics Consortium, Adan RAH, Alfredsson L, Ando T, Andreassen OA, Baker JH, Berrettini WH, Boehm I, Boni C, Perica VB, Buehren K, Burghardt R, Cassina M, Cichon S, Clementi M, Cone RD, Courtet P, Crow S, Crowley JJ, Danner UN, Davis OSP, de Zwaan M, Dedoussis G, Degortes D, DeSocio JE, Dick DM, Dikeos D, Dina C, Dmitrzak-Weglarz M, Docampo E, Duncan LE, Egberts K, Ehrlich S, Escaramís G, Esko T, Estivill X, Farmer A, Favaro A, Fernández-Aranda F, Fichter MM, Fischer K, Föcker M, Foretova L, Forstner AJ, Forzan M, Franklin CS, Gallinger S, Giegling I, Giuranna J, Gonidakis F, Gorwood P, Mayora MG, Guillaume S, Guo Y, Hakonarson H, Hatzikotoulas K, Hauser J, Hebebrand J, Helder SG, Herms S, Herpertz-Dahlmann B, Herzog W, Huckins LM, Hudson JI, Imgart H, Inoko H, Janout V, Jiménez-Murcia S, Julià A, Kalsi G, Kaminská D, Kaprio J, Karhunen L, Karwautz A, Kas MJH, Kennedy JL, Keski-Rahkonen A, Kiezebrink K, Kim YR, Klareskog L, Klump KL, Knudsen GPS, La Via MC, Le Hellard S, Levitan RD, Li D, Lilenfeld L, Lin BD, Lissowska J, Luykx J, Magistretti PJ, Maj M, Mannik K, Marsal S, Marshall CR, Mattingsdal M, McDevitt S, McGuffin P, Metspalu A, Meulenbelt I, Micali N, Mitchell K, Monteleone AM, Monteleone P, Munn-Chernoff MA, Nacmias B, Navratilova M, Ntalla I, O'Toole JK, Ophoff RA, Padyukov L, Palotie A, Pantel J, Papezova H, Pinto D, Rabionet R, Raevuori A, Ramoz N, Reichborn-Kjennerud T, Ricca V, Ripatti S, Ritschel F, Roberts M, Rotondo A, Rujescu D, Rybakowski F, Santonastaso P, Scherag A, Scherer SW, Schmidt U, Schork NJ, Schosser A, Seitz J, Slachtova L, Slagboom PE, Slof-Op 't Landt MCT, Slopien A, Sorbi S, Świątkowska B, Szatkiewicz JP, Tachmazidou I, Tenconi E, Tortorella A, Tozzi F, Treasure J, Tsitsika A, Tyszkiewicz-Nwafor M, Tziouvas K, van Elburg AA, van Furth EF, Wagner G, Walton E, Widen E, Zeggini E, Zerwas S, Zipfel S, Bergen AW, Boden JM, Brandt H, Crawford S, Halmi KA, Horwood LJ, Johnson C, Kaplan AS, Kaye WH, Mitchell JE, Olsen CM, Pearson JF, Pedersen NL, Strober M, Werge T, Whiteman DC, Woodside DB, Stuber GD, Gordon S, Grove J, Henders AK, Juréus A, Kirk KM, Larsen JT, Parker R, Petersen L, Jordan J, Kennedy M, Montgomery GW, Wade TD, Birgegård A, Lichtenstein P, Norring C, Landén M, Martin NG, Mortensen PB, Sullivan PF, Breen G, Bulik CM.

Nat Genet. 2019 Aug;51(8):1207-1214. doi: 10.1038/s41588-019-0439-2. Epub 2019 Jul 15.

PMID:
31308545
9.

The Strategic Location of Glycogen and Lactate: From Body Energy Reserve to Brain Plasticity.

Calì C, Tauffenberger A, Magistretti P.

Front Cell Neurosci. 2019 Mar 6;13:82. doi: 10.3389/fncel.2019.00082. eCollection 2019.

10.

An investigation of indirect effects of personality features on anorexia nervosa severity through interoceptive dysfunction in individuals with lifetime anorexia nervosa diagnoses.

Duffy ME, Rogers ML, Joiner TE, Bergen AW, Berrettini W, Bulik CM, Brandt H, Crawford S, Crow S, Fichter M, Halmi K, Kaplan AS, Klump KL, Lilenfeld L, Magistretti PJ, Mitchell J, Schork NJ, Strober M, Thornton LM, Treasure J, Woodside B, Kaye WH, Keel PK.

Int J Eat Disord. 2019 Feb;52(2):200-205. doi: 10.1002/eat.23008. Epub 2019 Jan 12.

PMID:
30636025
11.

Diabetes-free survival after extended distal pancreatectomy and islet auto transplantation for benign or borderline/malignant lesions of the pancreas.

Balzano G, Maffi P, Nano R, Mercalli A, Melzi R, Aleotti F, De Cobelli F, Magistretti P, Scavini M, Secchi A, Falconi M, Piemonti L.

Am J Transplant. 2019 Mar;19(3):920-928. doi: 10.1111/ajt.15219. Epub 2019 Jan 23.

PMID:
30549450
12.

Membrane water for probing neuronal membrane potentials and ionic fluxes at the single cell level.

Didier MEP, Tarun OB, Jourdain P, Magistretti P, Roke S.

Nat Commun. 2018 Dec 11;9(1):5287. doi: 10.1038/s41467-018-07713-w.

13.

The Epistemological Foundations of Freud's Energetics Model.

Tran The J, Magistretti P, Ansermet F.

Front Psychol. 2018 Oct 11;9:1861. doi: 10.3389/fpsyg.2018.01861. eCollection 2018. Review.

14.

L-Lactate Regulates the Expression of Synaptic Plasticity and Neuroprotection Genes in Cortical Neurons: A Transcriptome Analysis.

Margineanu MB, Mahmood H, Fiumelli H, Magistretti PJ.

Front Mol Neurosci. 2018 Oct 10;11:375. doi: 10.3389/fnmol.2018.00375. eCollection 2018.

15.

A Process for Digitizing and Simulating Biologically Realistic Oligocellular Networks Demonstrated for the Neuro-Glio-Vascular Ensemble.

Coggan JS, Calì C, Keller D, Agus M, Boges D, Abdellah M, Kare K, Lehväslaiho H, Eilemann S, Jolivet RB, Hadwiger M, Markram H, Schürmann F, Magistretti PJ.

Front Neurosci. 2018 Sep 25;12:664. doi: 10.3389/fnins.2018.00664. eCollection 2018.

16.

Dual action of L-Lactate on the activity of NR2B-containing NMDA receptors: from potentiation to neuroprotection.

Jourdain P, Rothenfusser K, Ben-Adiba C, Allaman I, Marquet P, Magistretti PJ.

Sci Rep. 2018 Sep 7;8(1):13472. doi: 10.1038/s41598-018-31534-y.

17.

Atlas of Circadian Metabolism Reveals System-wide Coordination and Communication between Clocks.

Dyar KA, Lutter D, Artati A, Ceglia NJ, Liu Y, Armenta D, Jastroch M, Schneider S, de Mateo S, Cervantes M, Abbondante S, Tognini P, Orozco-Solis R, Kinouchi K, Wang C, Swerdloff R, Nadeef S, Masri S, Magistretti P, Orlando V, Borrelli E, Uhlenhaut NH, Baldi P, Adamski J, Tschöp MH, Eckel-Mahan K, Sassone-Corsi P.

Cell. 2018 Sep 6;174(6):1571-1585.e11. doi: 10.1016/j.cell.2018.08.042.

18.

In vivo reprogramming of wound-resident cells generates skin epithelial tissue.

Kurita M, Araoka T, Hishida T, O'Keefe DD, Takahashi Y, Sakamoto A, Sakurai M, Suzuki K, Wu J, Yamamoto M, Hernandez-Benitez R, Ocampo A, Reddy P, Shokhirev MN, Magistretti P, Núñez Delicado E, Eto H, Harii K, Izpisua Belmonte JC.

Nature. 2018 Sep;561(7722):243-247. doi: 10.1038/s41586-018-0477-4. Epub 2018 Sep 5.

PMID:
30185909
19.

Norepinephrine stimulates glycogenolysis in astrocytes to fuel neurons with lactate.

Coggan JS, Keller D, Calì C, Lehväslaiho H, Markram H, Schürmann F, Magistretti PJ.

PLoS Comput Biol. 2018 Aug 30;14(8):e1006392. doi: 10.1371/journal.pcbi.1006392. eCollection 2018 Aug.

20.

Islet Allotransplantation in the Bone Marrow of Patients With Type 1 Diabetes: A Pilot Randomized Trial.

Maffi P, Nano R, Monti P, Melzi R, Sordi V, Mercalli A, Pellegrini S, Ponzoni M, Peccatori J, Messina C, Nocco A, Cardillo M, Scavini M, Magistretti P, Doglioni C, Ciceri F, Bloem SJ, Roep BO, Secchi A, Piemonti L.

Transplantation. 2019 Apr;103(4):839-851. doi: 10.1097/TP.0000000000002416.

PMID:
30130323
21.

Neuroscience without borders: Preserving the history of neuroscience.

Lorusso L, Piccolino M, Motta S, Gasparello A, Barbara JG, Bossi-Régnier L, Shepherd GM, Swanson L, Magistretti P, Everitt B, Molnár Z, Brown RE.

Eur J Neurosci. 2018 Sep;48(5):2099-2109. doi: 10.1111/ejn.14101. Epub 2018 Sep 9.

PMID:
30099790
22.

At the Heart of Genome Editing and Cardiovascular Diseases.

Hernandez-Benitez R, Martinez-Martinez ML, Lajara J, Magistretti P, Montserrat N, Izpisua Belmonte JC.

Circ Res. 2018 Jul 6;123(2):221-223. doi: 10.1161/CIRCRESAHA.118.312676. Review. No abstract available.

PMID:
29976689
23.

Hypertonic Lactate to Improve Cerebral Perfusion and Glucose Availability After Acute Brain Injury.

Carteron L, Solari D, Patet C, Quintard H, Miroz JP, Bloch J, Daniel RT, Hirt L, Eckert P, Magistretti PJ, Oddo M.

Crit Care Med. 2018 Oct;46(10):1649-1655. doi: 10.1097/CCM.0000000000003274.

PMID:
29923931
24.

Impact of MCT1 Haploinsufficiency on the Mouse Retina.

Peachey NS, Yu M, Han JYS, Lengacher S, Magistretti PJ, Pellerin L, Philp NJ.

Adv Exp Med Biol. 2018;1074:375-380. doi: 10.1007/978-3-319-75402-4_46.

25.

Lactate in the brain: from metabolic end-product to signalling molecule.

Magistretti PJ, Allaman I.

Nat Rev Neurosci. 2018 Apr;19(4):235-249. doi: 10.1038/nrn.2018.19. Epub 2018 Mar 8. Review.

PMID:
29515192
26.

Hypocretin/orexin deficiency decreases cocaine abuse liability.

Steiner N, Rossetti C, Sakurai T, Yanagisawa M, de Lecea L, Magistretti PJ, Halfon O, Boutrel B.

Neuropharmacology. 2018 May 1;133:395-403. doi: 10.1016/j.neuropharm.2018.02.010. Epub 2018 Feb 15.

27.

Inadequate brain glycogen or sleep increases spreading depression susceptibility.

Kilic K, Karatas H, Dönmez-Demir B, Eren-Kocak E, Gursoy-Ozdemir Y, Can A, Petit JM, Magistretti PJ, Dalkara T.

Ann Neurol. 2018 Jan;83(1):61-73. doi: 10.1002/ana.25122.

PMID:
29244233
28.

Gender-specific alteration of energy balance and circadian locomotor activity in the Crtc1 knockout mouse model of depression.

Rossetti C, Sciarra D, Petit JM, Eap CB, Halfon O, Magistretti PJ, Boutrel B, Cardinaux JR.

Transl Psychiatry. 2017 Dec 8;7(12):1269. doi: 10.1038/s41398-017-0023-4.

29.

Abstractocyte: A Visual Tool for Exploring Nanoscale Astroglial Cells.

Mohammed H, Al-Awami AK, Beyer J, Cali C, Magistretti P, Pfister H, Hadwiger M.

IEEE Trans Vis Comput Graph. 2018 Jan;24(1):853-861. doi: 10.1109/TVCG.2017.2744278. Epub 2017 Aug 29.

PMID:
28866534
30.

A preclinical model for identifying rats at risk of alcohol use disorder.

Jadhav KS, Magistretti PJ, Halfon O, Augsburger M, Boutrel B.

Sci Rep. 2017 Aug 25;7(1):9454. doi: 10.1038/s41598-017-09801-1.

31.

A Historical Review of Diachrony and Semantic Dimensions of Trace in Neurosciences and Lacanian Psychoanalysis.

Escobar C, Ansermet F, Magistretti PJ.

Front Psychol. 2017 Jun 23;8:734. doi: 10.3389/fpsyg.2017.00734. eCollection 2017. Review.

32.

Gathering by the Red Sea highlights links between environment and epigenetics.

Li M, Borrelli E, Magistretti PJ, Izpisua Belmonte JC, Sassone-Corsi P, Orlando V.

Nat Struct Mol Biol. 2017 Jun 6;24(6):491-493. doi: 10.1038/nsmb.3422. No abstract available.

PMID:
28586330
33.

Salvage Islet Auto Transplantation After Relaparatomy.

Balzano G, Nano R, Maffi P, Mercalli A, Melzi R, Aleotti F, Gavazzi F, Berra C, De Cobelli F, Venturini M, Magistretti P, Scavini M, Capretti G, Del Maschio A, Secchi A, Zerbi A, Falconi M, Piemonti L.

Transplantation. 2017 Oct;101(10):2492-2500. doi: 10.1097/TP.0000000000001750.

PMID:
28358727
34.

Role of MCT1 and CAII in skeletal muscle pH homeostasis, energetics, and function: in vivo insights from MCT1 haploinsufficient mice.

Chatel B, Bendahan D, Hourdé C, Pellerin L, Lengacher S, Magistretti P, Le Fur Y, Vilmen C, Bernard M, Messonnier LA.

FASEB J. 2017 Jun;31(6):2562-2575. doi: 10.1096/fj.201601259R. Epub 2017 Mar 2.

PMID:
28254758
35.

Peripheral administration of lactate produces antidepressant-like effects.

Carrard A, Elsayed M, Margineanu M, Boury-Jamot B, Fragnière L, Meylan EM, Petit JM, Fiumelli H, Magistretti PJ, Martin JL.

Mol Psychiatry. 2018 Feb;23(2):488. doi: 10.1038/mp.2016.237. Epub 2016 Dec 6.

36.

In vivo genome editing via CRISPR/Cas9 mediated homology-independent targeted integration.

Suzuki K, Tsunekawa Y, Hernandez-Benitez R, Wu J, Zhu J, Kim EJ, Hatanaka F, Yamamoto M, Araoka T, Li Z, Kurita M, Hishida T, Li M, Aizawa E, Guo S, Chen S, Goebl A, Soligalla RD, Qu J, Jiang T, Fu X, Jafari M, Esteban CR, Berggren WT, Lajara J, Nuñez-Delicado E, Guillen P, Campistol JM, Matsuzaki F, Liu GH, Magistretti P, Zhang K, Callaway EM, Zhang K, Belmonte JC.

Nature. 2016 Dec 1;540(7631):144-149. doi: 10.1038/nature20565. Epub 2016 Nov 16.

37.

A Motion Capture Study to Measure the Feeling of Synchrony in Romantic Couples and in Professional Musicians.

Preissmann D, Charbonnier C, Chagué S, Antonietti JP, Llobera J, Ansermet F, Magistretti PJ.

Front Psychol. 2016 Oct 27;7:1673. eCollection 2016.

38.

Peripheral administration of lactate produces antidepressant-like effects.

Carrard A, Elsayed M, Margineanu M, Boury-Jamot B, Fragnière L, Meylan EM, Petit JM, Fiumelli H, Magistretti PJ, Martin JL.

Mol Psychiatry. 2018 Feb;23(2):392-399. doi: 10.1038/mp.2016.179. Epub 2016 Oct 18. Erratum in: Mol Psychiatry. 2018 Feb;23 (2):488.

39.

Lactate release from astrocytes to neurons contributes to cocaine memory formation.

Boury-Jamot B, Halfon O, Magistretti PJ, Boutrel B.

Bioessays. 2016 Dec;38(12):1266-1273. doi: 10.1002/bies.201600118. Epub 2016 Oct 4. Review.

PMID:
27699812
40.

Protein targeting to glycogen is a master regulator of glycogen synthesis in astrocytes.

Ruchti E, Roach PJ, DePaoli-Roach AA, Magistretti PJ, Allaman I.

IBRO Rep. 2016 Oct 4;1:46-53. doi: 10.1016/j.ibror.2016.10.002. eCollection 2016 Dec.

41.

Involvement of the agmatinergic system in the depressive-like phenotype of the Crtc1 knockout mouse model of depression.

Meylan EM, Breuillaud L, Seredenina T, Magistretti PJ, Halfon O, Luthi-Carter R, Cardinaux JR.

Transl Psychiatry. 2016 Jul 12;6(7):e852. doi: 10.1038/tp.2016.116.

42.

Astrocytic β2-adrenergic receptors mediate hippocampal long-term memory consolidation.

Gao V, Suzuki A, Magistretti PJ, Lengacher S, Pollonini G, Steinman MQ, Alberini CM.

Proc Natl Acad Sci U S A. 2016 Jul 26;113(30):8526-31. doi: 10.1073/pnas.1605063113. Epub 2016 Jul 8.

43.

Imaging brain aerobic glycolysis as a marker of synaptic plasticity.

Magistretti PJ.

Proc Natl Acad Sci U S A. 2016 Jun 28;113(26):7015-6. doi: 10.1073/pnas.1607423113. Epub 2016 Jun 17. No abstract available.

44.

A Role for Lactate in the Consolidation of Drug-Related Associative Memories.

Boutrel B, Magistretti PJ.

Biol Psychiatry. 2016 Jun 1;79(11):875-7. doi: 10.1016/j.biopsych.2016.04.010. No abstract available.

PMID:
27198521
45.

Glutamate Cysteine Ligase-Modulatory Subunit Knockout Mouse Shows Normal Insulin Sensitivity but Reduced Liver Glycogen Storage.

Lavoie S, Steullet P, Kulak A, Preitner F, Do KQ, Magistretti PJ.

Front Physiol. 2016 Apr 21;7:142. doi: 10.3389/fphys.2016.00142. eCollection 2016.

46.

Sleep fragmentation alters brain energy metabolism without modifying hippocampal electrophysiological response to novelty exposure.

Baud MO, Parafita J, Nguyen A, Magistretti PJ, Petit JM.

J Sleep Res. 2016 Oct;25(5):583-590. doi: 10.1111/jsr.12419. Epub 2016 May 3.

47.

Sodium signaling and astrocyte energy metabolism.

Chatton JY, Magistretti PJ, Barros LF.

Glia. 2016 Oct;64(10):1667-76. doi: 10.1002/glia.22971. Epub 2016 Mar 29. Review.

48.

The HDAC inhibitor SAHA improves depressive-like behavior of CRTC1-deficient mice: Possible relevance for treatment-resistant depression.

Meylan EM, Halfon O, Magistretti PJ, Cardinaux JR.

Neuropharmacology. 2016 Aug;107:111-121. doi: 10.1016/j.neuropharm.2016.03.012. Epub 2016 Mar 9.

49.

L-Lactate protects neurons against excitotoxicity: implication of an ATP-mediated signaling cascade.

Jourdain P, Allaman I, Rothenfusser K, Fiumelli H, Marquet P, Magistretti PJ.

Sci Rep. 2016 Feb 19;6:21250. doi: 10.1038/srep21250.

50.

The Subjective Sensation of Synchrony: An Experimental Study.

Llobera J, Charbonnier C, Chagué S, Preissmann D, Antonietti JP, Ansermet F, Magistretti PJ.

PLoS One. 2016 Feb 12;11(2):e0147008. doi: 10.1371/journal.pone.0147008. eCollection 2016.

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