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Items: 34

1.

Plasmepsin II-III copy number accounts for bimodal piperaquine resistance among Cambodian Plasmodium falciparum.

Bopp S, Magistrado P, Wong W, Schaffner SF, Mukherjee A, Lim P, Dhorda M, Amaratunga C, Woodrow CJ, Ashley EA, White NJ, Dondorp AM, Fairhurst RM, Ariey F, Menard D, Wirth DF, Volkman SK.

Nat Commun. 2018 May 2;9(1):1769. doi: 10.1038/s41467-018-04104-z.

2.

Mapping the malaria parasite druggable genome by using in vitro evolution and chemogenomics.

Cowell AN, Istvan ES, Lukens AK, Gomez-Lorenzo MG, Vanaerschot M, Sakata-Kato T, Flannery EL, Magistrado P, Owen E, Abraham M, LaMonte G, Painter HJ, Williams RM, Franco V, Linares M, Arriaga I, Bopp S, Corey VC, Gnädig NF, Coburn-Flynn O, Reimer C, Gupta P, Murithi JM, Moura PA, Fuchs O, Sasaki E, Kim SW, Teng CH, Wang LT, Akidil A, Adjalley S, Willis PA, Siegel D, Tanaseichuk O, Zhong Y, Zhou Y, Llinás M, Ottilie S, Gamo FJ, Lee MCS, Goldberg DE, Fidock DA, Wirth DF, Winzeler EA.

Science. 2018 Jan 12;359(6372):191-199. doi: 10.1126/science.aan4472.

3.

Artemisinin resistance without pfkelch13 mutations in Plasmodium falciparum isolates from Cambodia.

Mukherjee A, Bopp S, Magistrado P, Wong W, Daniels R, Demas A, Schaffner S, Amaratunga C, Lim P, Dhorda M, Miotto O, Woodrow C, Ashley EA, Dondorp AM, White NJ, Wirth D, Fairhurst R, Volkman SK.

Malar J. 2017 May 12;16(1):195. doi: 10.1186/s12936-017-1845-5.

4.

Plasmodium falciparum Cyclic Amine Resistance Locus (PfCARL), a Resistance Mechanism for Two Distinct Compound Classes.

Magistrado PA, Corey VC, Lukens AK, LaMonte G, Sasaki E, Meister S, Wree M, Winzeler E, Wirth DF.

ACS Infect Dis. 2016 Nov 11;2(11):816-826. Epub 2016 Apr 7.

5.

A broad analysis of resistance development in the malaria parasite.

Corey VC, Lukens AK, Istvan ES, Lee MCS, Franco V, Magistrado P, Coburn-Flynn O, Sakata-Kato T, Fuchs O, Gnädig NF, Goldgof G, Linares M, Gomez-Lorenzo MG, De Cózar C, Lafuente-Monasterio MJ, Prats S, Meister S, Tanaseichuk O, Wree M, Zhou Y, Willis PA, Gamo FJ, Goldberg DE, Fidock DA, Wirth DF, Winzeler EA.

Nat Commun. 2016 Jun 15;7:11901. doi: 10.1038/ncomms11901.

6.

Triethysilyl Enol Ethers in the Synthesis of Carbapenem Precursors.

Nguyen TQ, Chai W, Gu J, Cook K, Kim E, Goetz S, Farni Z, Chepuru M, Cox M, Nguyen P, Raja H, Magistrado P, Michael F, Oelschlaeger P, Buynak JD.

Tetrahedron Lett. 2015 Jun 3;56(23):3385-3389.

7.

IgG antibodies to endothelial protein C receptor-binding cysteine-rich interdomain region domains of Plasmodium falciparum erythrocyte membrane protein 1 are acquired early in life in individuals exposed to malaria.

Turner L, Lavstsen T, Mmbando BP, Wang CW, Magistrado PA, Vestergaard LS, Ishengoma DS, Minja DT, Lusingu JP, Theander TG.

Infect Immun. 2015 Aug;83(8):3096-103. doi: 10.1128/IAI.00271-15. Epub 2015 May 26.

8.

Triaminopyrimidine is a fast-killing and long-acting antimalarial clinical candidate.

Hameed P S, Solapure S, Patil V, Henrich PP, Magistrado PA, Bharath S, Murugan K, Viswanath P, Puttur J, Srivastava A, Bellale E, Panduga V, Shanbag G, Awasthy D, Landge S, Morayya S, Koushik K, Saralaya R, Raichurkar A, Rautela N, Roy Choudhury N, Ambady A, Nandishaiah R, Reddy J, Prabhakar KR, Menasinakai S, Rudrapatna S, Chatterji M, Jiménez-Díaz MB, Martínez MS, Sanz LM, Coburn-Flynn O, Fidock DA, Lukens AK, Wirth DF, Bandodkar B, Mukherjee K, McLaughlin RE, Waterson D, Rosenbrier-Ribeiro L, Hickling K, Balasubramanian V, Warner P, Hosagrahara V, Dudley A, Iyer PS, Narayanan S, Kavanagh S, Sambandamurthy VK.

Nat Commun. 2015 Mar 31;6:6715. doi: 10.1038/ncomms7715.

9.

Aminoazabenzimidazoles, a novel class of orally active antimalarial agents.

Hameed P S, Chinnapattu M, Shanbag G, Manjrekar P, Koushik K, Raichurkar A, Patil V, Jatheendranath S, Rudrapatna SS, Barde SP, Rautela N, Awasthy D, Morayya S, Narayan C, Kavanagh S, Saralaya R, Bharath S, Viswanath P, Mukherjee K, Bandodkar B, Srivastava A, Panduga V, Reddy J, Prabhakar KR, Sinha A, Jiménez-Díaz MB, Martínez MS, Angulo-Barturen I, Ferrer S, Sanz LM, Gamo FJ, Duffy S, Avery VM, Magistrado PA, Lukens AK, Wirth DF, Waterson D, Balasubramanian V, Iyer PS, Narayanan S, Hosagrahara V, Sambandamurthy VK, Ramachandran S.

J Med Chem. 2014 Jul 10;57(13):5702-13. doi: 10.1021/jm500535j. Epub 2014 Jun 24.

PMID:
24914738
10.

Plasmodium falciparum mutant haplotype infection during pregnancy associated with reduced birthweight, Tanzania.

Minja DT, Schmiegelow C, Mmbando B, Boström S, Oesterholt M, Magistrado P, Pehrson C, John D, Salanti A, Luty AJ, Lemnge M, Theander T, Lusingu J, Alifrangis M.

Emerg Infect Dis. 2013;19(9). doi: 10.3201/eid1909.130133.

11.

Severe malaria is associated with parasite binding to endothelial protein C receptor.

Turner L, Lavstsen T, Berger SS, Wang CW, Petersen JE, Avril M, Brazier AJ, Freeth J, Jespersen JS, Nielsen MA, Magistrado P, Lusingu J, Smith JD, Higgins MK, Theander TG.

Nature. 2013 Jun 27;498(7455):502-5. doi: 10.1038/nature12216. Epub 2013 Jun 5.

12.

Malaria and fetal growth alterations in the 3(rd) trimester of pregnancy: a longitudinal ultrasound study.

Schmiegelow C, Minja D, Oesterholt M, Pehrson C, Suhrs HE, Boström S, Lemnge M, Magistrado P, Rasch V, Nielsen BB, Lusingu J, Theander TG.

PLoS One. 2013;8(1):e53794. doi: 10.1371/journal.pone.0053794. Epub 2013 Jan 11.

13.

Development of a fetal weight chart using serial trans-abdominal ultrasound in an East African population: a longitudinal observational study.

Schmiegelow C, Scheike T, Oesterholt M, Minja D, Pehrson C, Magistrado P, Lemnge M, Rasch V, Lusingu J, Theander TG, Nielsen BB.

PLoS One. 2012;7(9):e44773. doi: 10.1371/journal.pone.0044773. Epub 2012 Sep 21.

14.

Identification and characterization of B-cell epitopes in the DBL4ε domain of VAR2CSA.

Ditlev SB, Nielsen MA, Resende M, Agerbæk MØ, Pinto VV, Andersen PH, Magistrado P, Lusingu J, Dahlbäck M, Theander TG, Salanti A.

PLoS One. 2012;7(9):e43663. doi: 10.1371/journal.pone.0043663. Epub 2012 Sep 6.

15.

Reliability of rapid diagnostic tests in diagnosing pregnancy-associated malaria in north-eastern Tanzania.

Minja DT, Schmiegelow C, Oesterholt M, Magistrado PA, Boström S, John D, Pehrson C, Andersen D, Deloron P, Salanti A, Lemnge M, Luty AJ, Alifrangis M, Theander T, Lusingu JP.

Malar J. 2012 Jun 21;11:211.

16.

Factors associated with and causes of perinatal mortality in northeastern Tanzania.

Schmiegelow C, Minja D, Oesterholt M, Pehrson C, Suhrs HE, Boström S, Lemnge M, Magistrado P, Rasch V, Lusingu J, Theander TG, Bruun Nielsen B.

Acta Obstet Gynecol Scand. 2012 Sep;91(9):1061-8. doi: 10.1111/j.1600-0412.2012.01478.x.

PMID:
22676243
17.

Plasmodium falciparum erythrocyte membrane protein 1 domain cassettes 8 and 13 are associated with severe malaria in children.

Lavstsen T, Turner L, Saguti F, Magistrado P, Rask TS, Jespersen JS, Wang CW, Berger SS, Baraka V, Marquard AM, Seguin-Orlando A, Willerslev E, Gilbert MT, Lusingu J, Theander TG.

Proc Natl Acad Sci U S A. 2012 Jun 26;109(26):E1791-800. doi: 10.1073/pnas.1120455109. Epub 2012 May 22.

18.

Evidence for in vitro and in vivo expression of the conserved VAR3 (type 3) plasmodium falciparum erythrocyte membrane protein 1.

Wang CW, Lavstsen T, Bengtsson DC, Magistrado PA, Berger SS, Marquard AM, Alifrangis M, Lusingu JP, Theander TG, Turner L.

Malar J. 2012 Apr 25;11:129. doi: 10.1186/1475-2875-11-129.

19.

Accuracy of malaria rapid diagnostic tests in community studies and their impact on treatment of malaria in an area with declining malaria burden in north-eastern Tanzania.

Ishengoma DS, Francis F, Mmbando BP, Lusingu JP, Magistrado P, Alifrangis M, Theander TG, Bygbjerg IC, Lemnge MM.

Malar J. 2011 Jun 26;10:176. doi: 10.1186/1475-2875-10-176.

20.

Chondroitin sulfate A-adhering Plasmodium falciparum-infected erythrocytes express functionally important antibody epitopes shared by multiple variants.

Barfod L, Dobrilovic T, Magistrado P, Khunrae P, Viwami F, Bruun J, Dahlbäck M, Bernasconi NL, Fried M, John D, Duffy PE, Salanti A, Lanzavecchia A, Lim CT, Ndam NT, Higgins MK, Hviid L.

J Immunol. 2010 Dec 15;185(12):7553-61. doi: 10.4049/jimmunol.1002390. Epub 2010 Nov 15.

21.

High efficacy of anti DBL4ɛ-VAR2CSA antibodies in inhibition of CSA-binding Plasmodium falciparum-infected erythrocytes from pregnant women.

Magistrado PA, Minja D, Doritchamou J, Ndam NT, John D, Schmiegelow C, Massougbodji A, Dahlbäck M, Ditlev SB, Pinto VV, Resende M, Lusingu J, Theander TG, Salanti A, Nielsen MA.

Vaccine. 2011 Jan 10;29(3):437-43. doi: 10.1016/j.vaccine.2010.10.080. Epub 2010 Nov 12.

PMID:
21075162
22.

Multiple var2csa-type PfEMP1 genes located at different chromosomal loci occur in many Plasmodium falciparum isolates.

Sander AF, Salanti A, Lavstsen T, Nielsen MA, Magistrado P, Lusingu J, Ndam NT, Arnot DE.

PLoS One. 2009 Aug 19;4(8):e6667. doi: 10.1371/journal.pone.0006667.

23.

Preferential transcription of conserved rif genes in two phenotypically distinct Plasmodium falciparum parasite lines.

Wang CW, Magistrado PA, Nielsen MA, Theander TG, Lavstsen T.

Int J Parasitol. 2009 May;39(6):655-64. doi: 10.1016/j.ijpara.2008.11.014. Epub 2008 Dec 30.

PMID:
19162031
24.

CD36 selection of 3D7 Plasmodium falciparum associated with severe childhood malaria results in reduced VAR4 expression.

Magistrado PA, Staalsoe T, Theander TG, Hviid L, Jensen AT.

Malar J. 2008 Oct 9;7:204. doi: 10.1186/1475-2875-7-204.

25.

VAR2CSA expression on the surface of placenta-derived Plasmodium falciparum-infected erythrocytes.

Magistrado P, Salanti A, Tuikue Ndam NG, Mwakalinga SB, Resende M, Dahlbäck M, Hviid L, Lusingu J, Theander TG, Nielsen MA.

J Infect Dis. 2008 Oct 1;198(7):1071-4. doi: 10.1086/591502.

PMID:
18700835
26.

Immunoglobulin G antibody reactivity to a group A Plasmodium falciparum erythrocyte membrane protein 1 and protection from P. falciparum malaria.

Magistrado PA, Lusingu J, Vestergaard LS, Lemnge M, Lavstsen T, Turner L, Hviid L, Jensen AT, Theander TG.

Infect Immun. 2007 May;75(5):2415-20. Epub 2007 Feb 5.

27.
28.

Limited cross-reactivity among domains of the Plasmodium falciparum clone 3D7 erythrocyte membrane protein 1 family.

Joergensen L, Turner L, Magistrado P, Dahlbäck MA, Vestergaard LS, Lusingu JP, Lemnge M, Salanti A, Theander TG, Jensen AT.

Infect Immun. 2006 Dec;74(12):6778-84. Epub 2006 Oct 2.

29.

Expression of Plasmodium falciparum erythrocyte membrane protein 1 in experimentally infected humans.

Lavstsen T, Magistrado P, Hermsen CC, Salanti A, Jensen AT, Sauerwein R, Hviid L, Theander TG, Staalsoe T.

Malar J. 2005 Apr 27;4:21.

30.

Evidence for the involvement of VAR2CSA in pregnancy-associated malaria.

Salanti A, Dahlbäck M, Turner L, Nielsen MA, Barfod L, Magistrado P, Jensen AT, Lavstsen T, Ofori MF, Marsh K, Hviid L, Theander TG.

J Exp Med. 2004 Nov 1;200(9):1197-203.

31.

Plasmodium falciparum associated with severe childhood malaria preferentially expresses PfEMP1 encoded by group A var genes.

Jensen AT, Magistrado P, Sharp S, Joergensen L, Lavstsen T, Chiucchiuini A, Salanti A, Vestergaard LS, Lusingu JP, Hermsen R, Sauerwein R, Christensen J, Nielsen MA, Hviid L, Sutherland C, Staalsoe T, Theander TG.

J Exp Med. 2004 May 3;199(9):1179-90.

32.

Plasmodium falciparum phospholipase C hydrolyzing sphingomyelin and lysocholinephospholipids is a possible target for malaria chemotherapy.

Hanada K, Palacpac NM, Magistrado PA, Kurokawa K, Rai G, Sakata D, Hara T, Horii T, Nishijima M, Mitamura T.

J Exp Med. 2002 Jan 7;195(1):23-34.

33.

Isolation and polymerase chain reaction-based detection of Campylobacter jejuni and Campylobacter coli from poultry in the Philippines.

Magistrado PA, Garcia MM, Raymundo AK.

Int J Food Microbiol. 2001 Oct 22;70(1-2):197-206.

PMID:
11759758
34.

Neutral sphingomyelinase activity dependent on Mg2+ and anionic phospholipids in the intraerythrocytic malaria parasite Plasmodium falciparum.

Hanada K, Mitamura T, Fukasawa M, Magistrado PA, Horii T, Nishijima M.

Biochem J. 2000 Mar 15;346 Pt 3:671-7.

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