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Items: 44

1.

ROBO2 is a stroma suppressor gene in the pancreas and acts via TGF-β signalling.

Pinho AV, Van Bulck M, Chantrill L, Arshi M, Sklyarova T, Herrmann D, Vennin C, Gallego-Ortega D, Mawson A, Giry-Laterriere M, Magenau A, Leuckx G, Baeyens L, Gill AJ, Phillips P, Timpson P, Biankin AV, Wu J, Rooman I.

Nat Commun. 2018 Nov 30;9(1):5083. doi: 10.1038/s41467-018-07497-z.

2.

Removing physiological motion from intravital and clinical functional imaging data.

Warren SC, Nobis M, Magenau A, Mohammed YH, Herrmann D, Moran I, Vennin C, Conway JR, Mélénec P, Cox TR, Wang Y, Morton JP, Welch HC, Strathdee D, Anderson KI, Phan TG, Roberts MS, Timpson P.

Elife. 2018 Jul 9;7. pii: e35800. doi: 10.7554/eLife.35800.

3.

Intravital Imaging to Monitor Therapeutic Response in Moving Hypoxic Regions Resistant to PI3K Pathway Targeting in Pancreatic Cancer.

Conway JRW, Warren SC, Herrmann D, Murphy KJ, Cazet AS, Vennin C, Shearer RF, Killen MJ, Magenau A, Mélénec P, Pinese M, Nobis M, Zaratzian A, Boulghourjian A, Da Silva AM, Del Monte-Nieto G, Adam ASA, Harvey RP, Haigh JJ, Wang Y, Croucher DR, Sansom OJ, Pajic M, Caldon CE, Morton JP, Timpson P.

Cell Rep. 2018 Jun 12;23(11):3312-3326. doi: 10.1016/j.celrep.2018.05.038.

4.

A RhoA-FRET Biosensor Mouse for Intravital Imaging in Normal Tissue Homeostasis and Disease Contexts.

Nobis M, Herrmann D, Warren SC, Kadir S, Leung W, Killen M, Magenau A, Stevenson D, Lucas MC, Reischmann N, Vennin C, Conway JRW, Boulghourjian A, Zaratzian A, Law AM, Gallego-Ortega D, Ormandy CJ, Walters SN, Grey ST, Bailey J, Chtanova T, Quinn JMW, Baldock PA, Croucher PI, Schwarz JP, Mrowinska A, Zhang L, Herzog H, Masedunskas A, Hardeman EC, Gunning PW, Del Monte-Nieto G, Harvey RP, Samuel MS, Pajic M, McGhee EJ, Johnsson AE, Sansom OJ, Welch HCE, Morton JP, Strathdee D, Anderson KI, Timpson P.

Cell Rep. 2017 Oct 3;21(1):274-288. doi: 10.1016/j.celrep.2017.09.022.

5.

Transient tissue priming via ROCK inhibition uncouples pancreatic cancer progression, sensitivity to chemotherapy, and metastasis.

Vennin C, Chin VT, Warren SC, Lucas MC, Herrmann D, Magenau A, Melenec P, Walters SN, Del Monte-Nieto G, Conway JR, Nobis M, Allam AH, McCloy RA, Currey N, Pinese M, Boulghourjian A, Zaratzian A, Adam AA, Heu C, Nagrial AM, Chou A, Steinmann A, Drury A, Froio D, Giry-Laterriere M, Harris NL, Phan T, Jain R, Weninger W, McGhee EJ, Whan R, Johns AL, Samra JS, Chantrill L, Gill AJ, Kohonen-Corish M, Harvey RP, Biankin AV; Australian Pancreatic Cancer Genome Initiative (APGI), Evans TR, Anderson KI, Grey ST, Ormandy CJ, Gallego-Ortega D, Wang Y, Samuel MS, Sansom OJ, Burgess A, Cox TR, Morton JP, Pajic M, Timpson P.

Sci Transl Med. 2017 Apr 5;9(384). pii: eaai8504. doi: 10.1126/scitranslmed.aai8504.

6.

Distinct surveillance pathway for immunopathology during acute infection via autophagy and SR-BI.

Pfeiler S, Khandagale AB, Magenau A, Nichols M, Heijnen HF, Rinninger F, Ziegler T, Seveau S, Schubert S, Zahler S, Verschoor A, Latz E, Massberg S, Gaus K, Engelmann B.

Sci Rep. 2016 Oct 3;6:34440. doi: 10.1038/srep34440.

7.

Activation of Endothelial Nitric Oxide (eNOS) Occurs through Different Membrane Domains in Endothelial Cells.

Tran J, Magenau A, Rodriguez M, Rentero C, Royo T, Enrich C, Thomas SR, Grewal T, Gaus K.

PLoS One. 2016 Mar 15;11(3):e0151556. doi: 10.1371/journal.pone.0151556. eCollection 2016.

8.

Intravital FRAP Imaging using an E-cadherin-GFP Mouse Reveals Disease- and Drug-Dependent Dynamic Regulation of Cell-Cell Junctions in Live Tissue.

Erami Z, Herrmann D, Warren SC, Nobis M, McGhee EJ, Lucas MC, Leung W, Reischmann N, Mrowinska A, Schwarz JP, Kadir S, Conway JRW, Vennin C, Karim SA, Campbell AD, Gallego-Ortega D, Magenau A, Murphy KJ, Ridgway RA, Law AM, Walters SN, Grey ST, Croucher DR, Zhang L, Herzog H, Hardeman EC, Gunning PW, Ormandy CJ, Evans TRJ, Strathdee D, Sansom OJ, Morton JP, Anderson KI, Timpson P.

Cell Rep. 2016 Jan 5;14(1):152-167. doi: 10.1016/j.celrep.2015.12.020. Epub 2015 Dec 24.

9.

ELF5 Drives Lung Metastasis in Luminal Breast Cancer through Recruitment of Gr1+ CD11b+ Myeloid-Derived Suppressor Cells.

Gallego-Ortega D, Ledger A, Roden DL, Law AM, Magenau A, Kikhtyak Z, Cho C, Allerdice SL, Lee HJ, Valdes-Mora F, Herrmann D, Salomon R, Young AI, Lee BY, Sergio CM, Kaplan W, Piggin C, Conway JR, Rabinovich B, Millar EK, Oakes SR, Chtanova T, Swarbrick A, Naylor MJ, O'Toole S, Green AR, Timpson P, Gee JM, Ellis IO, Clark SJ, Ormandy CJ.

PLoS Biol. 2015 Dec 30;13(12):e1002330. doi: 10.1371/journal.pbio.1002330. eCollection 2015 Dec.

10.

A Negative Regulatory Mechanism Involving 14-3-3ζ Limits Signaling Downstream of ROCK to Regulate Tissue Stiffness in Epidermal Homeostasis.

Kular J, Scheer KG, Pyne NT, Allam AH, Pollard AN, Magenau A, Wright RL, Kolesnikoff N, Moretti PA, Wullkopf L, Stomski FC, Cowin AJ, Woodcock JM, Grimbaldeston MA, Pitson SM, Timpson P, Ramshaw HS, Lopez AF, Samuel MS.

Dev Cell. 2015 Dec 21;35(6):759-74. doi: 10.1016/j.devcel.2015.11.026.

11.

Genetically targeted fluorogenic macromolecules for subcellular imaging and cellular perturbation.

Magenau AJ, Saurabh S, Andreko SK, Telmer CA, Schmidt BF, Waggoner AS, Bruchez MP.

Biomaterials. 2015 Oct;66:1-8. doi: 10.1016/j.biomaterials.2015.07.002. Epub 2015 Jul 2.

12.

High mammographic density is associated with an increase in stromal collagen and immune cells within the mammary epithelium.

Huo CW, Chew G, Hill P, Huang D, Ingman W, Hodson L, Brown KA, Magenau A, Allam AH, McGhee E, Timpson P, Henderson MA, Thompson EW, Britt K.

Breast Cancer Res. 2015 Jun 4;17:79. doi: 10.1186/s13058-015-0592-1.

13.

Discreet and distinct clustering of five model membrane proteins revealed by single molecule localization microscopy.

Magenau A, Owen DM, Yamamoto Y, Tran J, Kwiatek JM, Parton RG, Gaus K.

Mol Membr Biol. 2015;32(1):11-8. doi: 10.3109/09687688.2014.990997. Epub 2015 Jan 14.

PMID:
25586872
14.

Monitoring the dynamics of Src activity in response to anti-invasive dasatinib treatment at a subcellular level using dual intravital imaging.

Nobis M, McGhee EJ, Herrmann D, Magenau A, Morton JP, Anderson KI, Timpson P.

Cell Adh Migr. 2014;8(5):478-86. doi: 10.4161/19336918.2014.970004.

15.

Evidence for annexin A6-dependent plasma membrane remodelling of lipid domains.

Alvarez-Guaita A, Vilà de Muga S, Owen DM, Williamson D, Magenau A, García-Melero A, Reverter M, Hoque M, Cairns R, Cornely R, Tebar F, Grewal T, Gaus K, Ayala-Sanmartín J, Enrich C, Rentero C.

Br J Pharmacol. 2015 Apr;172(7):1677-90. doi: 10.1111/bph.13022. Epub 2015 Jan 20.

16.

3D super-resolution imaging by localization microscopy.

Magenau A, Gaus K.

Methods Mol Biol. 2015;1232:123-36. doi: 10.1007/978-1-4939-1752-5_11.

PMID:
25331133
17.

Biointerfaces on indium-tin oxide prepared from organophosphonic acid self-assembled monolayers.

Chockalingam M, Magenau A, Parker SG, Parviz M, Vivekchand SR, Gaus K, Gooding JJ.

Langmuir. 2014 Jul 22;30(28):8509-15. doi: 10.1021/la501774b. Epub 2014 Jul 8.

PMID:
24960524
18.

Three-dimensional cancer models mimic cell-matrix interactions in the tumour microenvironment.

Herrmann D, Conway JR, Vennin C, Magenau A, Hughes WE, Morton JP, Timpson P.

Carcinogenesis. 2014 Aug;35(8):1671-9. doi: 10.1093/carcin/bgu108. Epub 2014 Jun 5. Review.

PMID:
24903340
19.

Antibody modified porous silicon microparticles for the selective capture of cells.

Guan B, Magenau A, Ciampi S, Gaus K, Reece PJ, Gooding JJ.

Bioconjug Chem. 2014 Jul 16;25(7):1282-9. doi: 10.1021/bc500144u. Epub 2014 Jun 10.

PMID:
24892699
20.

Versatile "click chemistry" approach to functionalizing silicon quantum dots: applications toward fluorescent cellular imaging.

Cheng X, Lowe SB, Ciampi S, Magenau A, Gaus K, Reece PJ, Gooding JJ.

Langmuir. 2014 May 13;30(18):5209-16. doi: 10.1021/la500945f. Epub 2014 Apr 28.

PMID:
24716818
21.

Single-molecule analysis reveals self assembly and nanoscale segregation of two distinct cavin subcomplexes on caveolae.

Gambin Y, Ariotti N, McMahon KA, Bastiani M, Sierecki E, Kovtun O, Polinkovsky ME, Magenau A, Jung W, Okano S, Zhou Y, Leneva N, Mureev S, Johnston W, Gaus K, Hancock JF, Collins BM, Alexandrov K, Parton RG.

Elife. 2013 Jan 1;3:e01434. doi: 10.7554/eLife.01434.

22.

Quantitative analysis of three-dimensional fluorescence localization microscopy data.

Owen DM, Williamson DJ, Boelen L, Magenau A, Rossy J, Gaus K.

Biophys J. 2013 Jul 16;105(2):L05-7. doi: 10.1016/j.bpj.2013.05.063.

23.

Creating adhesive and soluble gradients for imaging cell migration with fluorescence microscopy.

Ngalim SH, Magenau A, Zhu Y, Tønnesen L, Fairjones Z, Gooding JJ, Böcking T, Gaus K.

J Vis Exp. 2013 Apr 4;(74). doi: 10.3791/50310.

24.

Sub-resolution lipid domains exist in the plasma membrane and regulate protein diffusion and distribution.

Owen DM, Williamson DJ, Magenau A, Gaus K.

Nat Commun. 2012;3:1256. doi: 10.1038/ncomms2273.

PMID:
23212385
25.

Super-resolution imaging by localization microscopy.

Owen DM, Magenau A, Williamson DJ, Gaus K.

Methods Mol Biol. 2013;950:81-93. doi: 10.1007/978-1-62703-137-0_6.

PMID:
23086871
26.

Preparation of cationic nanogels for nucleic acid delivery.

Averick SE, Paredes E, Irastorza A, Shrivats AR, Srinivasan A, Siegwart DJ, Magenau AJ, Cho HY, Hsu E, Averick AA, Kim J, Liu S, Hollinger JO, Das SR, Matyjaszewski K.

Biomacromolecules. 2012 Nov 12;13(11):3445-9. doi: 10.1021/bm301166s. Epub 2012 Oct 2.

PMID:
22967138
27.

Using an electrical potential to reversibly switch surfaces between two states for dynamically controlling cell adhesion.

Ng CC, Magenau A, Ngalim SH, Ciampi S, Chockalingham M, Harper JB, Gaus K, Gooding JJ.

Angew Chem Int Ed Engl. 2012 Jul 27;51(31):7706-10. doi: 10.1002/anie.201202118. Epub 2012 Jun 22.

PMID:
22730419
28.

The lipid raft hypothesis revisited--new insights on raft composition and function from super-resolution fluorescence microscopy.

Owen DM, Magenau A, Williamson D, Gaus K.

Bioessays. 2012 Sep;34(9):739-47. doi: 10.1002/bies.201200044. Epub 2012 Jun 14. Review.

PMID:
22696155
29.

Optical techniques for imaging membrane domains in live cells (live-cell palm of protein clustering).

Owen DM, Williamson D, Magenau A, Gaus K.

Methods Enzymol. 2012;504:221-35. doi: 10.1016/B978-0-12-391857-4.00011-2. Review.

PMID:
22264537
30.

Quantitative imaging of membrane lipid order in cells and organisms.

Owen DM, Rentero C, Magenau A, Abu-Siniyeh A, Gaus K.

Nat Protoc. 2011 Dec 8;7(1):24-35. doi: 10.1038/nprot.2011.419.

PMID:
22157973
31.

Controlled aqueous atom transfer radical polymerization with electrochemical generation of the active catalyst.

Bortolamei N, Isse AA, Magenau AJ, Gennaro A, Matyjaszewski K.

Angew Chem Int Ed Engl. 2011 Nov 25;50(48):11391-4. doi: 10.1002/anie.201105317. Epub 2011 Sep 16. No abstract available.

PMID:
21922623
32.

Phagocytosis of IgG-coated polystyrene beads by macrophages induces and requires high membrane order.

Magenau A, Benzing C, Proschogo N, Don AS, Hejazi L, Karunakaran D, Jessup W, Gaus K.

Traffic. 2011 Dec;12(12):1730-43. doi: 10.1111/j.1600-0854.2011.01272.x. Epub 2011 Sep 21.

33.

Spacing of integrin ligands influences signal transduction in endothelial cells.

Le Saux G, Magenau A, Gunaratnam K, Kilian KA, Böcking T, Gooding JJ, Gaus K.

Biophys J. 2011 Aug 17;101(4):764-73. doi: 10.1016/j.bpj.2011.06.064.

34.

The relative importance of topography and RGD ligand density for endothelial cell adhesion.

Le Saux G, Magenau A, Böcking T, Gaus K, Gooding JJ.

PLoS One. 2011;6(7):e21869. doi: 10.1371/journal.pone.0021869. Epub 2011 Jul 11.

35.

Pre-existing clusters of the adaptor Lat do not participate in early T cell signaling events.

Williamson DJ, Owen DM, Rossy J, Magenau A, Wehrmann M, Gooding JJ, Gaus K.

Nat Immunol. 2011 Jun 5;12(7):655-62. doi: 10.1038/ni.2049.

PMID:
21642986
36.

Electrochemically mediated atom transfer radical polymerization.

Magenau AJ, Strandwitz NC, Gennaro A, Matyjaszewski K.

Science. 2011 Apr 1;332(6025):81-4. doi: 10.1126/science.1202357.

37.

Mesoporous silicon photonic crystal microparticles: towards single-cell optical biosensors.

Guan B, Magenau A, Kilian KA, Ciampi S, Gaus K, Reece PJ, Gooding JJ.

Faraday Discuss. 2011;149:301-17; discussion 333-56.

PMID:
21413188
38.

Imaging membrane lipid order in whole, living vertebrate organisms.

Owen DM, Magenau A, Majumdar A, Gaus K.

Biophys J. 2010 Jul 7;99(1):L7-9. doi: 10.1016/j.bpj.2010.04.022.

39.

How do cells make decisions: engineering micro- and nanoenvironments for cell migration.

Ngalim SH, Magenau A, Le Saux G, Gooding JJ, Gaus K.

J Oncol. 2010;2010:363106. doi: 10.1155/2010/363106. Epub 2010 Jun 23.

40.

α- and β-crystallins modulate the head group order of human lens membranes during aging.

Zhu X, Gaus K, Lu Y, Magenau A, Truscott RJ, Mitchell TW.

Invest Ophthalmol Vis Sci. 2010 Oct;51(10):5162-7. doi: 10.1167/iovs.09-4947. Epub 2010 May 19.

41.

PALM imaging and cluster analysis of protein heterogeneity at the cell surface.

Owen DM, Rentero C, Rossy J, Magenau A, Williamson D, Rodriguez M, Gaus K.

J Biophotonics. 2010 Jul;3(7):446-54. doi: 10.1002/jbio.200900089.

PMID:
20148419
42.

Flotillins are involved in the polarization of primitive and mature hematopoietic cells.

Rajendran L, Beckmann J, Magenau A, Boneberg EM, Gaus K, Viola A, Giebel B, Illges H.

PLoS One. 2009 Dec 22;4(12):e8290. doi: 10.1371/journal.pone.0008290.

43.

Smart tissue culture: in situ monitoring of the activity of protease enzymes secreted from live cells using nanostructured photonic crystals.

Kilian KA, Lai LM, Magenau A, Cartland S, Böcking T, Di Girolamo N, Gal M, Gaus K, Gooding JJ.

Nano Lett. 2009 May;9(5):2021-5. doi: 10.1021/nl900283j.

PMID:
19382766
44.

Endothelial cells are protected against phagocyte-transmitted Chlamydophila pneumoniae infections by laminar shear stress Gueinzius: Shear stress protects from C. pneumoniae infection.

Gueinzius K, Magenau A, Erath S, Wittke V, Urbich C, Ferrando-May E, Dimmeler S, Hermann C.

Atherosclerosis. 2008 Jun;198(2):256-63. Epub 2007 Dec 4.

PMID:
18054938

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