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Items: 30

1.

Human genetics and neuropathology suggest a link between miR-218 and amyotrophic lateral sclerosis pathophysiology.

Reichenstein I, Eitan C, Diaz-Garcia S, Haim G, Magen I, Siany A, Hoye ML, Rivkin N, Olender T, Toth B, Ravid R, Mandelbaum AD, Yanowski E, Liang J, Rymer JK, Levy R, Beck G, Ainbinder E, Farhan SMK, Lennox KA, Bode NM, Behlke MA, Möller T, Saxena S, Moreno CAM, Costaguta G, van Eijk KR, Phatnani H, Al-Chalabi A, Başak AN, van den Berg LH, Hardiman O, Landers JE, Mora JS, Morrison KE, Shaw PJ, Veldink JH, Pfaff SL, Yizhar O, Gross C, Brown RH Jr, Ravits JM, Harms MB, Miller TM, Hornstein E.

Sci Transl Med. 2019 Dec 18;11(523). pii: eaav5264. doi: 10.1126/scitranslmed.aav5264.

2.

Evaluation of methodologies for microRNA biomarker detection by next generation sequencing.

Coenen-Stass AML, Magen I, Brooks T, Ben-Dov IZ, Greensmith L, Hornstein E, Fratta P.

RNA Biol. 2018;15(8):1133-1145. doi: 10.1080/15476286.2018.1514236. Epub 2018 Sep 18.

3.

Chronic nicotine improves cognitive and social impairment in mice overexpressing wild type α-synuclein.

Subramaniam SR, Magen I, Bove N, Zhu C, Lemesre V, Dutta G, Elias CJ, Lester HA, Chesselet MF.

Neurobiol Dis. 2018 Sep;117:170-180. doi: 10.1016/j.nbd.2018.05.018. Epub 2018 Jun 1.

4.

2-Arachidonoylglycerol as a possible treatment for anorexia nervosa in animal model in mice.

Avraham Y, Paturski I, Magen I, Vorobiev L, Berry EM.

Brain Res. 2017 Sep 1;1670:185-190. doi: 10.1016/j.brainres.2017.06.003. Epub 2017 Jun 9.

PMID:
28606779
5.

A Molecular Tweezer Ameliorates Motor Deficits in Mice Overexpressing α-Synuclein.

Richter F, Subramaniam SR, Magen I, Lee P, Hayes J, Attar A, Zhu C, Franich NR, Bove N, De La Rosa K, Kwong J, Klärner FG, Schrader T, Chesselet MF, Bitan G.

Neurotherapeutics. 2017 Oct;14(4):1107-1119. doi: 10.1007/s13311-017-0544-9.

6.

ALS Along the Axons - Expression of Coding and Noncoding RNA Differs in Axons of ALS models.

Rotem N, Magen I, Ionescu A, Gershoni-Emek N, Altman T, Costa CJ, Gradus T, Pasmanik-Chor M, Willis DE, Ben-Dov IZ, Hornstein E, Perlson E.

Sci Rep. 2017 Mar 16;7:44500. doi: 10.1038/srep44500.

7.

Dysregulated miRNA biogenesis downstream of cellular stress and ALS-causing mutations: a new mechanism for ALS.

Emde A, Eitan C, Liou LL, Libby RT, Rivkin N, Magen I, Reichenstein I, Oppenheim H, Eilam R, Silvestroni A, Alajajian B, Ben-Dov IZ, Aebischer J, Savidor A, Levin Y, Sons R, Hammond SM, Ravits JM, Möller T, Hornstein E.

EMBO J. 2015 Nov 3;34(21):2633-51. doi: 10.15252/embj.201490493. Epub 2015 Sep 1.

8.

Activity-dependent neuroprotective protein (ADNP) exhibits striking sexual dichotomy impacting on autistic and Alzheimer's pathologies.

Malishkevich A, Amram N, Hacohen-Kleiman G, Magen I, Giladi E, Gozes I.

Transl Psychiatry. 2015 Feb 3;5:e501. doi: 10.1038/tp.2014.138.

9.

Social Cognition Impairments in Mice Overexpressing Alpha-Synuclein Under the Thy1 Promoter, a Model of Pre-manifest Parkinson's Disease.

Magen I, Torres ER, Dinh D, Chung A, Masliah E, Chesselet MF.

J Parkinsons Dis. 2015;5(3):669-680. doi: 10.3233/JPD-140503.

10.

Intranasal NAP (davunetide) decreases tau hyperphosphorylation and moderately improves behavioral deficits in mice overexpressing α-synuclein.

Magen I, Ostritsky R, Richter F, Zhu C, Fleming SM, Lemesre V, Stewart AJ, Morimoto BH, Gozes I, Chesselet MF.

Pharmacol Res Perspect. 2014 Oct;2(5):e00065. doi: 10.1002/prp2.65. Epub 2014 Aug 6.

11.

Oligonucleotide-based therapy for neurodegenerative diseases.

Magen I, Hornstein E.

Brain Res. 2014 Oct 10;1584:116-28. doi: 10.1016/j.brainres.2014.04.005. Epub 2014 Apr 12. Review.

PMID:
24727531
12.

Davunetide: Peptide therapeutic in neurological disorders.

Magen I, Gozes I.

Curr Med Chem. 2014;21(23):2591-8. Review.

PMID:
24533805
13.

Microtubule-stabilizing peptides and small molecules protecting axonal transport and brain function: focus on davunetide (NAP).

Magen I, Gozes I.

Neuropeptides. 2013 Dec;47(6):489-95. doi: 10.1016/j.npep.2013.10.011. Epub 2013 Oct 24. Review.

PMID:
24210139
14.

Mice overexpressing wild-type human alpha-synuclein display alterations in colonic myenteric ganglia and defecation.

Wang L, Magen I, Yuan PQ, Subramaniam SR, Richter F, Chesselet MF, Taché Y.

Neurogastroenterol Motil. 2012 Sep;24(9):e425-36. doi: 10.1111/j.1365-2982.2012.01974.x. Epub 2012 Jul 11.

15.

Cognitive deficits in a mouse model of pre-manifest Parkinson's disease.

Magen I, Fleming SM, Zhu C, Garcia EC, Cardiff KM, Dinh D, De La Rosa K, Sanchez M, Torres ER, Masliah E, Jentsch JD, Chesselet MF.

Eur J Neurosci. 2012 Mar;35(6):870-82. doi: 10.1111/j.1460-9568.2012.08012.x. Epub 2012 Feb 22.

16.

A progressive mouse model of Parkinson's disease: the Thy1-aSyn ("Line 61") mice.

Chesselet MF, Richter F, Zhu C, Magen I, Watson MB, Subramaniam SR.

Neurotherapeutics. 2012 Apr;9(2):297-314. doi: 10.1007/s13311-012-0104-2. Review.

17.

Elevated tonic extracellular dopamine concentration and altered dopamine modulation of synaptic activity precede dopamine loss in the striatum of mice overexpressing human α-synuclein.

Lam HA, Wu N, Cely I, Kelly RL, Hean S, Richter F, Magen I, Cepeda C, Ackerson LC, Walwyn W, Masliah E, Chesselet MF, Levine MS, Maidment NT.

J Neurosci Res. 2011 Jul;89(7):1091-102. doi: 10.1002/jnr.22611. Epub 2011 Apr 12.

18.

Mouse models of cognitive deficits due to alpha-synuclein pathology.

Magen I, Chesselet MF.

J Parkinsons Dis. 2011;1(3):217-27. doi: 10.3233/JPD-2011-11043. Review.

PMID:
23939303
19.

Cannabidiol improves brain and liver function in a fulminant hepatic failure-induced model of hepatic encephalopathy in mice.

Avraham Y, Grigoriadis N, Poutahidis T, Vorobiev L, Magen I, Ilan Y, Mechoulam R, Berry E.

Br J Pharmacol. 2011 Apr;162(7):1650-8. doi: 10.1111/j.1476-5381.2010.01179.x.

20.

Fish oil promotes survival and protects against cognitive decline in severely undernourished mice by normalizing satiety signals.

Avraham Y, Saidian M, Burston JJ, Mevorach R, Vorobiev L, Magen I, Kunkes E, Borges B, Lichtman AH, Berry EM.

J Nutr Biochem. 2011 Aug;22(8):766-76. doi: 10.1016/j.jnutbio.2010.07.001. Epub 2010 Dec 15.

21.

Genetic mouse models of Parkinson's disease The state of the art.

Magen I, Chesselet MF.

Prog Brain Res. 2010;184:53-87. doi: 10.1016/S0079-6123(10)84004-X. Review.

PMID:
20887870
22.

Leptin reduces infarct size in association with enhanced expression of CB2, TRPV1, SIRT-1 and leptin receptor.

Avraham Y, Davidi N, Porat M, Chernoguz D, Magen I, Vorobeiv L, Berry EM, Leker RR.

Curr Neurovasc Res. 2010 May;7(2):136-43.

PMID:
20374198
23.

Cannabidiol ameliorates cognitive and motor impairments in bile-duct ligated mice via 5-HT1A receptor activation.

Magen I, Avraham Y, Ackerman Z, Vorobiev L, Mechoulam R, Berry EM.

Br J Pharmacol. 2010 Feb;159(4):950-7. doi: 10.1111/j.1476-5381.2009.00589.x. Epub 2010 Jan 29.

24.

Capsaicin affects brain function in a model of hepatic encephalopathy associated with fulminant hepatic failure in mice.

Avraham Y, Grigoriadis NC, Magen I, Poutahidis T, Vorobiav L, Zolotarev O, Ilan Y, Mechoulam R, Berry EM.

Br J Pharmacol. 2009 Oct;158(3):896-906. doi: 10.1111/j.1476-5381.2009.00368.x. Epub 2009 Sep 18.

25.

Cannabidiol ameliorates cognitive and motor impairments in mice with bile duct ligation.

Magen I, Avraham Y, Ackerman Z, Vorobiev L, Mechoulam R, Berry EM.

J Hepatol. 2009 Sep;51(3):528-34. doi: 10.1016/j.jhep.2009.04.021. Epub 2009 May 27.

PMID:
19596476
26.

Cannabinoids and capsaicin improve liver function following thioacetamide-induced acute injury in mice.

Avraham Y, Zolotarev O, Grigoriadis NC, Poutahidis T, Magen I, Vorobiav L, Zimmer A, Ilan Y, Mechoulam R, Berry EM.

Am J Gastroenterol. 2008 Dec;103(12):3047-56. doi: 10.1111/j.1572-0241.2008.02155.x. Erratum in: Am J Gastroenterol. 2009 Mar;104(3):801. Pautahidis, Theofilos [corrected to Poutahidis, Theofilos].

PMID:
19086956
27.

Endocannabinoids in liver disease and hepatic encephalopathy.

Magen I, Avraham Y, Berry E, Mechoulam R.

Curr Pharm Des. 2008;14(23):2362-9. Review.

PMID:
18781986
28.

2-Arachidonoylglycerol, an endogenous cannabinoid receptor agonist, in various rat tissues during the evolution of experimental cholestatic liver disease.

Avraham Y, Magen I, Zolotarev O, Vorobiav L, Nachmias A, Pappo O, Ilan Y, Berry EM, Ackerman Z.

Prostaglandins Leukot Essent Fatty Acids. 2008 Jul-Aug;79(1-2):35-40. doi: 10.1016/j.plefa.2008.07.003. Epub 2008 Sep 3.

PMID:
18771906
29.

Nutritional status, cognition, and survival: a new role for leptin and AMP kinase.

Dagon Y, Avraham Y, Magen I, Gertler A, Ben-Hur T, Berry EM.

J Biol Chem. 2005 Dec 23;280(51):42142-8. Epub 2005 Oct 3.

30.

Endocannabinoids affect neurological and cognitive function in thioacetamide-induced hepatic encephalopathy in mice.

Avraham Y, Israeli E, Gabbay E, Okun A, Zolotarev O, Silberman I, Ganzburg V, Dagon Y, Magen I, Vorobia L, Pappo O, Mechoulam R, Ilan Y, Berry EM.

Neurobiol Dis. 2006 Jan;21(1):237-45. Epub 2005 Aug 15.

PMID:
16102970

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