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Effects of isoniazid resistance on TB treatment outcomes under programmatic conditions in a high-TB and -HIV setting: a prospective multicentre study-authors' response.

Nagu TJ, Aboud S, Matee MI, Maeurer MJ, Fawzi WW, Mugusi F.

J Antimicrob Chemother. 2018 Jun 1;73(6):1735. doi: 10.1093/jac/dky104. No abstract available.


Tuberculosis: progress and advances in development of new drugs, treatment regimens, and host-directed therapies.

Tiberi S, du Plessis N, Walzl G, Vjecha MJ, Rao M, Ntoumi F, Mfinanga S, Kapata N, Mwaba P, McHugh TD, Ippolito G, Migliori GB, Maeurer MJ, Zumla A.

Lancet Infect Dis. 2018 Jul;18(7):e183-e198. doi: 10.1016/S1473-3099(18)30110-5. Epub 2018 Mar 23. Review. Erratum in: Lancet Infect Dis. 2018 Apr 27;:.


Bioinformatory-assisted analysis of next-generation sequencing data for precision medicine in pancreatic cancer.

Malgerud L, Lindberg J, Wirta V, Gustafsson-Liljefors M, Karimi M, Moro CF, Stecker K, Picker A, Huelsewig C, Stein M, Bohnert R, Del Chiaro M, Haas SL, Heuchel RL, Permert J, Maeurer MJ, Brock S, Verbeke CS, Engstrand L, Jackson DB, Grönberg H, Löhr JM.

Mol Oncol. 2017 Oct;11(10):1413-1429. doi: 10.1002/1878-0261.12108. Epub 2017 Aug 8.


A Preliminary Report: Radical Surgery and Stem Cell Transplantation for the Treatment of Patients With Pancreatic Cancer.

Omazic B, Ayoglu B, Löhr M, Segersvärd R, Verbeke C, Magalhaes I, Potacova Z, Mattsson J, Terman A, Ghazi S, Albiin N, Kartalis N, Nilsson P, Poiret T, Zhenjiang L, Heuchel R, Schwenk JM, Permert J, Maeurer MJ, Ringden O.

J Immunother. 2017 Mar 23. doi: 10.1097/CJI.0000000000000164. [Epub ahead of print]


IL-7δ5 protein is expressed in human tissues and induces expression of the oxidized low density lipoprotein receptor 1 (OLR1) in CD14+ monocytes.

Rane L, Rahman S, Magalhaes I, Ambati A, Andersson J, Zumla A, Brighenti S, Maeurer MJ.

Int J Infect Dis. 2017 Jun;59:29-36. doi: 10.1016/j.ijid.2017.03.001. Epub 2017 Mar 6.


Tuberculosis associated mortality in a prospective cohort in Sub Saharan Africa: Association with HIV and antiretroviral therapy.

Nagu TJ, Aboud S, Mwiru R, Matee MI, Rao M, Fawzi WW, Zumla A, Maeurer MJ, Mugusi F.

Int J Infect Dis. 2017 Mar;56:39-44. doi: 10.1016/j.ijid.2017.01.023. Epub 2017 Feb 1. Review.


Effects of isoniazid resistance on TB treatment outcomes under programmatic conditions in a high-TB and -HIV setting: a prospective multicentre study.

Nagu TJ, Aboud S, Matee MI, Maeurer MJ, Fawzi WW, Mugusi F.

J Antimicrob Chemother. 2017 Mar 1;72(3):876-881. doi: 10.1093/jac/dkw503.


Expansion of Tumor-reactive T Cells From Patients With Pancreatic Cancer.

Meng Q, Liu Z, Rangelova E, Poiret T, Ambati A, Rane L, Xie S, Verbeke C, Dodoo E, Del Chiaro M, Löhr M, Segersvärd R, Maeurer MJ.

J Immunother. 2016 Feb-Mar;39(2):81-9. doi: 10.1097/CJI.0000000000000111.


Whole CMV proteome pattern recognition analysis after HSCT identifies unique epitope targets associated with the CMV status.

Pérez-Bercoff L, Valentini D, Gaseitsiwe S, Mahdavifar S, Schutkowski M, Poiret T, Pérez-Bercoff Å, Ljungman P, Maeurer MJ.

PLoS One. 2014 Apr 16;9(4):e89648. doi: 10.1371/journal.pone.0089648. eCollection 2014.


Autologous mesenchymal stromal cell infusion as adjunct treatment in patients with multidrug and extensively drug-resistant tuberculosis: an open-label phase 1 safety trial.

Skrahin A, Ahmed RK, Ferrara G, Rane L, Poiret T, Isaikina Y, Skrahina A, Zumla A, Maeurer MJ.

Lancet Respir Med. 2014 Feb;2(2):108-22. doi: 10.1016/S2213-2600(13)70234-0. Epub 2014 Jan 9.


Systems level immune response analysis and personalized medicine.

Brodin P, Valentini D, Uhlin M, Mattsson J, Zumla A, Maeurer MJ.

Expert Rev Clin Immunol. 2013 Apr;9(4):307-17. doi: 10.1586/eci.13.9. Review.


Pattern recognition and cellular immune responses to novel Mycobacterium tuberculosis-antigens in individuals from Belarus.

Ahmed RK, Rohava Z, Balaji KN, Hoffner SE, Gaines H, Magalhaes I, Zumla A, Skrahina A, Maeurer MJ.

BMC Infect Dis. 2012 Feb 15;12:41. doi: 10.1186/1471-2334-12-41.


Increased (6 exon) interleukin-7 production after M. tuberculosis infection and soluble interleukin-7 receptor expression in lung tissue.

Rane L, Rahman S, Magalhaes I, Ahmed R, Spångberg M, Kondova I, Verreck F, Andersson J, Brighenti S, Maeurer MJ.

Genes Immun. 2011 Oct;12(7):513-22. doi: 10.1038/gene.2011.29. Epub 2011 Jun 16.


Decreased IL-7 signaling in T cells from patients with PTLD after allogeneic HSCT.

Omar H, Ahmed R, Rane L, Björklund A, Gustafsson-Jernberg A, Ljungman P, Maeurer MJ.

J Immunother. 2011 May;34(4):390-6. doi: 10.1097/CJI.0b013e318215e31b.


High content cellular immune profiling reveals differences between rhesus monkeys and men.

Magalhaes I, Vudattu NK, Ahmed RK, Kühlmann-Berenzon S, Ngo Y, Sizemore DR, Wehlin L, Weichold F, Andersson J, Skeiky YA, Sadoff J, Gaines H, Thorstensson R, Spångberg M, Maeurer MJ.

Immunology. 2010 Sep;131(1):128-40. doi: 10.1111/j.1365-2567.2010.03284.x. Epub 2010 May 10.


Alternative splicing of interleukin-7 (IL-7) and interleukin-7 receptor alpha (IL-7Ralpha) in peripheral blood from patients with multiple sclerosis (MS).

Rane L, Vudattu N, Bourcier K, Graniar E, Hillert J, Seyfert V, Maeurer MJ.

J Neuroimmunol. 2010 May;222(1-2):82-6. doi: 10.1016/j.jneuroim.2010.02.014. Epub 2010 Mar 11.


Extensive major histocompatibility complex class I binding promiscuity for Mycobacterium tuberculosis TB10.4 peptides and immune dominance of human leucocyte antigen (HLA)-B*0702 and HLA-B*0801 alleles in TB10.4 CD8 T-cell responses.

Axelsson-Robertson R, Weichold F, Sizemore D, Wulf M, Skeiky YA, Sadoff J, Maeurer MJ.

Immunology. 2010 Apr;129(4):496-505. doi: 10.1111/j.1365-2567.2009.03201.x. Epub 2009 Nov 25.


Interleukin-7 (IL-7) and IL-7 splice variants affect differentiation of human neural progenitor cells.

Moors M, Vudattu NK, Abel J, Krämer U, Rane L, Ulfig N, Ceccatelli S, Seyfert-Margolies V, Fritsche E, Maeurer MJ.

Genes Immun. 2010 Jan;11(1):11-20. doi: 10.1038/gene.2009.77. Epub 2009 Oct 22.


Increased numbers of IL-7 receptor molecules on CD4+CD25-CD107a+ T-cells in patients with autoimmune diseases affecting the central nervous system.

Vudattu NK, Kuhlmann-Berenzon S, Khademi M, Seyfert V, Olsson T, Maeurer MJ.

PLoS One. 2009 Aug 6;4(8):e6534. doi: 10.1371/journal.pone.0006534.


T-cell epitope mapping.

Ahmed RK, Maeurer MJ.

Methods Mol Biol. 2009;524:427-38. doi: 10.1007/978-1-59745-450-6_31.


Identification of MHC class II binding peptides: microarray and soluble MHC class II molecules.

Gaseitsiwe S, Maeurer MJ.

Methods Mol Biol. 2009;524:417-26. doi: 10.1007/978-1-59745-450-6_30.


Expression analysis and functional activity of interleukin-7 splice variants.

Vudattu NK, Magalhaes I, Hoehn H, Pan D, Maeurer MJ.

Genes Immun. 2009 Mar;10(2):132-40. doi: 10.1038/gene.2008.90. Epub 2008 Dec 18.


Pattern recognition in pulmonary tuberculosis defined by high content peptide microarray chip analysis representing 61 proteins from M. tuberculosis.

Gaseitsiwe S, Valentini D, Mahdavifar S, Magalhaes I, Hoft DF, Zerweck J, Schutkowski M, Andersson J, Reilly M, Maeurer MJ.

PLoS One. 2008;3(12):e3840. doi: 10.1371/journal.pone.0003840. Epub 2008 Dec 9.


Tumor antigen-specific T-cells are Present in the CD8alphaalpha+ T-cell effector-memory pool.

Magalhaes I, Vudattu NK, Jäger E, Maeurer MJ.

J Immunother. 2008 Nov-Dec;31(9):840-8. doi: 10.1097/CJI.0b013e31818883a1.


Reduced numbers of IL-7 receptor (CD127) expressing immune cells and IL-7-signaling defects in peripheral blood from patients with breast cancer.

Vudattu NK, Magalhaes I, Schmidt M, Seyfert-Margolis V, Maeurer MJ.

Int J Cancer. 2007 Oct 1;121(7):1512-9.


Impact of MHC class I alleles on the M. tuberculosis antigen-specific CD8+ T-cell response in patients with pulmonary tuberculosis.

Weichold FF, Mueller S, Kortsik C, Hitzler WE, Wulf MJ, Hone DM, Sadoff JC, Maeurer MJ.

Genes Immun. 2007 Jun;8(4):334-43. Epub 2007 Apr 12.


DRB1*0401-restricted human T cell clone specific for the major proinsulin73-90 epitope expresses a down-regulatory T helper 2 phenotype.

Durinovic-Belló I, Rosinger S, Olson JA, Congia M, Ahmad RC, Rickert M, Hampl J, Kalbacher H, Drijfhout JW, Mellins ED, Al Dahouk S, Kamradt T, Maeurer MJ, Nhan C, Roep BO, Boehm BO, Polychronakos C, Nepom GT, Karges W, McDevitt HO, Sønderstrup G.

Proc Natl Acad Sci U S A. 2006 Aug 1;103(31):11683-8. Epub 2006 Jul 25.


Differential MHC class II component expression in HPV-positive cervical cancer cells: implication for immune surveillance.

Zehbe I, Höhn H, Pilch H, Neukirch C, Freitag K, Maeurer MJ.

Int J Cancer. 2005 Dec 10;117(5):807-15.


Diagnosing Helicobacter pylori in vivo by confocal laser endoscopy.

Kiesslich R, Goetz M, Burg J, Stolte M, Siegel E, Maeurer MJ, Thomas S, Strand D, Galle PR, Neurath MF.

Gastroenterology. 2005 Jun;128(7):2119-23.


Highly focused T cell responses in latent human pulmonary Mycobacterium tuberculosis infection.

Tully G, Kortsik C, Höhn H, Zehbe I, Hitzler WE, Neukirch C, Freitag K, Kayser K, Maeurer MJ.

J Immunol. 2005 Feb 15;174(4):2174-84.


Naturally processed and HLA-B8-presented HPV16 E7 epitope recognized by T cells from patients with cervical cancer.

Oerke S, Höhn H, Zehbe I, Pilch H, Schicketanz KH, Hitzler WE, Neukirch C, Freitag K, Maeurer MJ.

Int J Cancer. 2005 May 1;114(5):766-78.


Human papillomavirus type 16 E7 peptide-directed CD8+ T cells from patients with cervical cancer are cross-reactive with the coronavirus NS2 protein.

Nilges K, Höhn H, Pilch H, Neukirch C, Freitag K, Talbot PJ, Maeurer MJ.

J Virol. 2003 May;77(9):5464-74.


Suboptimal activation of CD8(+) T cells by melanoma-derived altered peptide ligands: role of Melan-A/MART-1 optimized analogues.

Carrabba MG, Castelli C, Maeurer MJ, Squarcina P, Cova A, Pilla L, Renkvist N, Parmiani G, Rivoltini L.

Cancer Res. 2003 Apr 1;63(7):1560-7.


No association between Helicobacter pylori genotypes and antibiotic resistance phenotypes within families.

Zschausch HC, Han SR, Meyer HG, Maeurer MJ.

Helicobacter. 2002 Dec;7(6):364-6.


The T-cell response in patients with cancer.

Castelli C, Maeurer MJ.

Adv Cancer Res. 2002;86:149-93. Review. No abstract available.


Longitudinal analysis of the T-cell receptor (TCR)-VA and -VB repertoire in CD8+ T cells from individuals immunized with recombinant hepatitis B surface antigen.

Höhn H, Neukirch C, Freitag K, Necker A, Hitzler W, Seliger B, Maeurer MJ.

Clin Exp Immunol. 2002 Aug;129(2):309-17.


Regulation of CD1d expression by murine tumor cells: escape from immunosurveillance or alternate target molecules?

Fiedler T, Walter W, Reichert TE, Maeurer MJ.

Int J Cancer. 2002 Mar 20;98(3):389-97.


Peptide-specific CD8+ T-cell evolution in vivo: response to peptide vaccination with Melan-A/MART-1.

Jäger E, Höhn H, Necker A, Förster R, Karbach J, Freitag K, Neukirch C, Castelli C, Salter RD, Knuth A, Maeurer MJ.

Int J Cancer. 2002 Mar 20;98(3):376-88.


Impact of antigen presentation on TCR modulation and cytokine release: implications for detection and sorting of antigen-specific CD8+ T cells using HLA-A2 wild-type or HLA-A2 mutant tetrameric complexes.

Jäger E, Salter R, Castelli C, Höhn H, Freitag K, Karbach J, Neukirch C, Necker A, Knuth A, Maeurer MJ.

J Immunol. 2002 Mar 15;168(6):2766-72.


Antigen-driven T-cell selection in patients with cervical cancer as evidenced by T-cell receptor analysis and recognition of autologous tumor.

Pilch H, Höhn H, Neukirch C, Freitag K, Knapstein PG, Tanner B, Maeurer MJ.

Clin Diagn Lab Immunol. 2002 Mar;9(2):267-78.


Improved assessment of T-cell receptor (TCR) VB repertoire in clinical specimens: combination of TCR-CDR3 spectratyping with flow cytometry-based TCR VB frequency analysis.

Pilch H, Höhn H, Freitag K, Neukirch C, Necker A, Haddad P, Tanner B, Knapstein PG, Maeurer MJ.

Clin Diagn Lab Immunol. 2002 Mar;9(2):257-66.


The ability of variant peptides to reverse the nonresponsiveness of T lymphocytes to the wild-type sequence p53(264-272) epitope.

Hoffmann TK, Loftus DJ, Nakano K, Maeurer MJ, Chikamatsu K, Appella E, Whiteside TL, DeLeo AB.

J Immunol. 2002 Feb 1;168(3):1338-47.


Improved detection of melanoma antigen-specific T cells expressing low or high levels of CD8 by HLA-A2 tetramers presenting a Melan-A/Mart-1 peptide analogue.

Maeurer MJ, Necker A, Salter RD, Castelli C, Höhn H, Karbach J, Freitag K, Neukirch C, Knuth A, Jäger E.

Int J Cancer. 2002 Jan 1;97(1):64-71.


Reduced T-cell receptor CD3zeta-chain protein and sustained CD3epsilon expression at the site of mycobacterial infection.

Seitzer U, Kayser K, Höhn H, Entzian P, Wacker HH, Ploetz S, Flad HD, Gerdes J, Maeurer MJ.

Immunology. 2001 Nov;104(3):269-77.


Deficient expression of components of the MHC class I antigen processing machinery in human cervical carcinoma.

Ritz U, Momburg F, Pilch H, Huber C, Maeurer MJ, Seliger B.

Int J Oncol. 2001 Dec;19(6):1211-20.


Segregation of effector mechanisms in a tumour-specific CD8+ T-cell clone correlates with CD30 expression.

Sun Y, Song M, Maeurer MJ, Schadendorf D.

Scand J Immunol. 2001 Sep;54(3):314-20.

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