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Items: 1 to 50 of 77

1.

Vitamin D and Its Synthetic Analogs.

Maestro MA, Molnár F, Carlberg C.

J Med Chem. 2019 Aug 8;62(15):6854-6875. doi: 10.1021/acs.jmedchem.9b00208. Epub 2019 Apr 2.

2.

Synthesis of 28,28,28-trideutero-25-hydroxydihydrotachysterol2.

Sigüeiro R, Loureiro J, González-Berdullas P, Mouriño A, Maestro MA.

J Steroid Biochem Mol Biol. 2019 Jan;185:248-250. doi: 10.1016/j.jsbmb.2018.09.014. Epub 2018 Sep 19.

PMID:
30244048
3.

Total synthesis of 1α,25-dihydroxyvitamin D3 analogs modified at the side chain and D-ring.

López-Pérez B, Maestro MA, Mouriño A.

Org Biomol Chem. 2018 Jun 20;16(24):4563-4569. doi: 10.1039/c8ob01002a.

PMID:
29881848
4.

Aromatic-Based Design of Highly Active and Noncalcemic Vitamin D Receptor Agonists.

Gogoi P, Seoane S, Sigüeiro R, Guiberteau T, Maestro MA, Pérez-Fernández R, Rochel N, Mouriño A.

J Med Chem. 2018 Jun 14;61(11):4928-4937. doi: 10.1021/acs.jmedchem.8b00337. Epub 2018 May 22.

PMID:
29733645
5.

Synthesis of Side-Chain Locked Analogs of 1α,25-Dihydroxyvitamin D3 Bearing a C17 Methyl Group.

Sigüeiro R, Maestro MA, Mouriño A.

Org Lett. 2018 May 4;20(9):2641-2644. doi: 10.1021/acs.orglett.8b00849. Epub 2018 Apr 13.

PMID:
29652161
6.

Stereoselective Palladium-Catalyzed Approach to Vitamin D3 Derivatives in Protic Medium.

Carballa D, Sigüeiro R, Rodríguez-Docampo Z, Zacconi F, Maestro MA, Mouriño A.

Chemistry. 2018 Mar 2;24(13):3314-3320. doi: 10.1002/chem.201705656. Epub 2018 Feb 6.

PMID:
29239492
7.

Stereoselective synthesis of 25S,26-dihydroxyvitamin D3.

Sigüeiro R, González-Berdullas P, Loureiro J, Mouriño A, Maestro MA.

J Steroid Biochem Mol Biol. 2018 Mar;177:247-249. doi: 10.1016/j.jsbmb.2017.07.016. Epub 2017 Jul 18.

PMID:
28732680
8.

Total synthesis of 1α,25-dihydroxyvitamin D3 (calcitriol) through a Si-assisted allylic substitution.

López-Pérez B, Maestro MA, Mouriño A.

Chem Commun (Camb). 2017 Jul 18;53(58):8144-8147. doi: 10.1039/c7cc04690a.

PMID:
28678281
9.

Vitamin D receptor 2016: novel ligands and structural insights.

Maestro MA, Molnár F, Mouriño A, Carlberg C.

Expert Opin Ther Pat. 2016 Nov;26(11):1291-1306. Epub 2016 Aug 12. Review.

PMID:
27454349
10.

A new approach to 19-nor-A-ring phosphine oxide for the convergent synthesis of 19-nor-calcitriol.

Sigüeiro R, Otero R, González-Berdullas P, Loureiro J, Mouriño A, Maestro MA.

J Steroid Biochem Mol Biol. 2017 Oct;173:86-88. doi: 10.1016/j.jsbmb.2016.08.008. Epub 2016 Aug 31.

PMID:
27592138
11.

Carborane-based design of a potent vitamin D receptor agonist.

Otero R, Seoane S, Sigüeiro R, Belorusova AY, Maestro MA, Pérez-Fernández R, Rochel N, Mouriño A.

Chem Sci. 2016 Feb 1;7(2):1033-1037. doi: 10.1039/c5sc03084f. Epub 2015 Oct 27.

12.

Stereoselective synthesis of 1β,25-Dihydroxyvitamin D3 and its 26,27-hexadeuterated derivative.

Loureiro J, Maestro MA, Mouriño A, Sigüeiro R.

J Steroid Biochem Mol Biol. 2016 Nov;164:56-58. doi: 10.1016/j.jsbmb.2015.09.007. Epub 2015 Sep 9.

PMID:
26363188
13.

TEAD and YAP regulate the enhancer network of human embryonic pancreatic progenitors.

Cebola I, Rodríguez-Seguí SA, Cho CH, Bessa J, Rovira M, Luengo M, Chhatriwala M, Berry A, Ponsa-Cobas J, Maestro MA, Jennings RE, Pasquali L, Morán I, Castro N, Hanley NA, Gomez-Skarmeta JL, Vallier L, Ferrer J.

Nat Cell Biol. 2015 May;17(5):615-626. doi: 10.1038/ncb3160. Epub 2015 Apr 27.

14.

Quantitative analytical method to evaluate the metabolism of vitamin D.

Mena-Bravo A, Ferreiro-Vera C, Priego-Capote F, Maestro MA, Mouriño A, Quesada-Gómez JM, Luque de Castro MD.

Clin Chim Acta. 2015 Mar 10;442:6-12. doi: 10.1016/j.cca.2014.12.039. Epub 2015 Jan 7.

PMID:
25575651
15.

Impact of cosmetic result on selection of surgical treatment in patients with localized prostate cancer.

Rojo MA, Martinez-Salamanca JI, Maestro MA, Galarza IS, Rodriguez JC.

JSLS. 2014 Oct-Dec;18(4). pii: e2014.00024. doi: 10.4293/JSLS.2014.00024.

16.

Ins1(Cre) knock-in mice for beta cell-specific gene recombination.

Thorens B, Tarussio D, Maestro MA, Rovira M, Heikkilä E, Ferrer J.

Diabetologia. 2015 Mar;58(3):558-65. doi: 10.1007/s00125-014-3468-5. Epub 2014 Dec 11.

17.

The biliary epithelium gives rise to liver progenitor cells.

Rodrigo-Torres D, Affò S, Coll M, Morales-Ibanez O, Millán C, Blaya D, Alvarez-Guaita A, Rentero C, Lozano JJ, Maestro MA, Solar M, Arroyo V, Caballería J, van Grunsven LA, Enrich C, Ginès P, Bataller R, Sancho-Bru P.

Hepatology. 2014 Oct;60(4):1367-77. doi: 10.1002/hep.27078. Epub 2014 Aug 21.

18.

Pancreatic islet enhancer clusters enriched in type 2 diabetes risk-associated variants.

Pasquali L, Gaulton KJ, Rodríguez-Seguí SA, Mularoni L, Miguel-Escalada I, Akerman İ, Tena JJ, Morán I, Gómez-Marín C, van de Bunt M, Ponsa-Cobas J, Castro N, Nammo T, Cebola I, García-Hurtado J, Maestro MA, Pattou F, Piemonti L, Berney T, Gloyn AL, Ravassard P, Skarmeta JLG, Müller F, McCarthy MI, Ferrer J.

Nat Genet. 2014 Feb;46(2):136-143. doi: 10.1038/ng.2870. Epub 2014 Jan 12.

19.

Synthesis of nonadeuterated 1α,25-dihydroxyvitamin D2.

Sigüeiro R, Álvarez A, Otero R, López-Pérez B, Carballa D, Regueira T, González-Berdullas P, Seoane S, Pérez-Fernández R, Mouriño A, Maestro MA.

J Steroid Biochem Mol Biol. 2014 Oct;144 Pt A:204-6. doi: 10.1016/j.jsbmb.2013.10.025. Epub 2013 Nov 1. Review.

PMID:
24189543
20.

Base-dependent stereodivergent intramolecular aza-Michael reaction: asymmetric synthesis of 1,3-disubstituted isoindolines.

Fustero S, Herrera L, Lázaro R, Rodríguez E, Maestro MA, Mateu N, Barrio P.

Chemistry. 2013 Aug 26;19(35):11776-85. doi: 10.1002/chem.201301591. Epub 2013 Jul 12.

PMID:
23852920
21.

An efficient synthesis of 1α,25-dihydroxy-20-epi-vitamin D3.

Fraga R, López-Pérez B, Sokolowska K, Guini A, Regueira T, Díaz S, Mouriño A, Maestro MA.

J Steroid Biochem Mol Biol. 2013 Jul;136:14-6. doi: 10.1016/j.jsbmb.2013.01.010. Epub 2013 Feb 6. Review.

PMID:
23396126
22.

Gold-catalyzed intramolecular hydroamination of o-alkynylbenzyl carbamates: a route to chiral fluorinated isoindoline and isoquinoline derivatives.

Fustero S, Ibáñez I, Barrio P, Maestro MA, Catalán S.

Org Lett. 2013 Feb 15;15(4):832-5. doi: 10.1021/ol3035142. Epub 2013 Jan 29.

PMID:
23360473
23.

Gold catalyzed stereoselective tandem hydroamination-formal aza-Diels-Alder reaction of propargylic amino esters.

Fustero S, Bello P, Miró J, Sánchez-Roselló M, Maestro MA, González J, del Pozo C.

Chem Commun (Camb). 2013 Feb 14;49(13):1336-8. doi: 10.1039/c2cc37796a. Epub 2013 Jan 10.

PMID:
23303342
24.

Ring1b bookmarks genes in pancreatic embryonic progenitors for repression in adult β cells.

van Arensbergen J, García-Hurtado J, Maestro MA, Correa-Tapia M, Rutter GA, Vidal M, Ferrer J.

Genes Dev. 2013 Jan 1;27(1):52-63. doi: 10.1101/gad.206094.112. Epub 2012 Dec 27.

25.

Radical urethrectomy with bladder preservation and continent catheterizable stoma (Yang-Monti tecnique).

Maestro MA, Martinez-Piñeiro L, Gonzalez ER.

Indian J Urol. 2012 Jan;28(1):107-10. doi: 10.4103/0970-1591.94971.

26.

Penile metastasis of rectal carcinoma. Case report and bibliographic review.

Maestro MA, Martínez-Piñeiro L, Moreno SS, Rodríguez JD, Quevedo AL.

Arch Esp Urol. 2011 Dec;64(10):981-4. English, Spanish.

PMID:
22228896
27.

Intramolecular Michael reaction of tert-butylsulfinyl ketimines: asymmetric synthesis of 3-substituted indanones.

Fustero S, Rodríguez E, Herrera L, Asensio A, Maestro MA, Barrio P.

Org Lett. 2011 Dec 16;13(24):6564-7. doi: 10.1021/ol2028948. Epub 2011 Nov 23.

PMID:
22111789
28.

Synthesis and characterization of metallodendritic palladium-biscarbene complexes derived from 1,1'-methylenebis(1,2,4-triazole).

Hornillos V, Guerra J, de Cózar A, Prieto P, Merino S, Maestro MA, Díez-Barra E, Tejeda J.

Dalton Trans. 2011 Apr 28;40(16):4095-103. doi: 10.1039/c0dt01535k. Epub 2011 Mar 7.

PMID:
21384005
29.

Hnf1α (MODY3) regulates β-cell-enriched MafA transcription factor expression.

Hunter CS, Maestro MA, Raum JC, Guo M, Thompson FH 3rd, Ferrer J, Stein R.

Mol Endocrinol. 2011 Feb;25(2):339-47. doi: 10.1210/me.2010-0362. Epub 2010 Dec 30.

30.

Derepression of Polycomb targets during pancreatic organogenesis allows insulin-producing beta-cells to adopt a neural gene activity program.

van Arensbergen J, García-Hurtado J, Moran I, Maestro MA, Xu X, Van de Casteele M, Skoudy AL, Palassini M, Heimberg H, Ferrer J.

Genome Res. 2010 Jun;20(6):722-32. doi: 10.1101/gr.101709.109. Epub 2010 Apr 15.

31.

Recessive mutations in the INS gene result in neonatal diabetes through reduced insulin biosynthesis.

Garin I, Edghill EL, Akerman I, Rubio-Cabezas O, Rica I, Locke JM, Maestro MA, Alshaikh A, Bundak R, del Castillo G, Deeb A, Deiss D, Fernandez JM, Godbole K, Hussain K, O'Connell M, Klupa T, Kolouskova S, Mohsin F, Perlman K, Sumnik Z, Rial JM, Ugarte E, Vasanthi T; Neonatal Diabetes International Group, Johnstone K, Flanagan SE, Martínez R, Castaño C, Patch AM, Fernández-Rebollo E, Raile K, Morgan N, Harries LW, Castaño L, Ellard S, Ferrer J, Perez de Nanclares G, Hattersley AT.

Proc Natl Acad Sci U S A. 2010 Feb 16;107(7):3105-10. doi: 10.1073/pnas.0910533107. Epub 2010 Jan 28.

32.

Pancreatic exocrine duct cells give rise to insulin-producing beta cells during embryogenesis but not after birth.

Solar M, Cardalda C, Houbracken I, Martín M, Maestro MA, De Medts N, Xu X, Grau V, Heimberg H, Bouwens L, Ferrer J.

Dev Cell. 2009 Dec;17(6):849-60. doi: 10.1016/j.devcel.2009.11.003.

33.

X-ray diffraction, solution structure, and computational studies on derivatives of (3-sec-butyl-2,3-dihydro-1H-isoquinolin-4-ylidene)acetic acid: compounds with activity as calpain inhibitors.

Alonso M, Chicharro R, Miranda C, Arán VJ, Maestro MA, Herradón B.

J Org Chem. 2010 Jan 15;75(2):342-52. doi: 10.1021/jo902091u.

PMID:
20014819
34.

Laparoscopic transperitoneal radical prostatectomy in renal transplant recipients: a review of the literature.

Maestro MA, Gómez AT, Alonso Y Gregorio S, Ledo JC, de la Peña Barthel J, Martínez-Piñeiro L.

BJU Int. 2010 Mar;105(6):844-8. doi: 10.1111/j.1464-410X.2009.08911.x. Epub 2009 Oct 5. Review.

35.

Conjugate addition of nitroalkanes to an acrylate equivalent. Stereocontrol at C-alpha of the nitro group through double catalytic activation.

García JM, Maestro MA, Oiarbide M, Odriozola JM, Razkin J, Palomo C.

Org Lett. 2009 Sep 3;11(17):3826-9. doi: 10.1021/ol901351k.

PMID:
19663464
36.

Hnf1alpha (MODY3) controls tissue-specific transcriptional programs and exerts opposed effects on cell growth in pancreatic islets and liver.

Servitja JM, Pignatelli M, Maestro MA, Cardalda C, Boj SF, Lozano J, Blanco E, Lafuente A, McCarthy MI, Sumoy L, Guigó R, Ferrer J.

Mol Cell Biol. 2009 Jun;29(11):2945-59. doi: 10.1128/MCB.01389-08. Epub 2009 Mar 16.

37.

Structure, magnetic properties and nuclease activity of pyridine-2-carbaldehyde thiosemicarbazonecopper(II) complexes.

Gómez-Saiz P, Gil-García R, Maestro MA, Pizarro JL, Arriortua MI, Lezama L, Rojo T, González-Alvarez M, Borrás J, García-Tojal J.

J Inorg Biochem. 2008 Oct;102(10):1910-20. doi: 10.1016/j.jinorgbio.2008.06.015. Epub 2008 Jul 1.

PMID:
18692903
38.

Targeted deficiency of the transcriptional activator Hnf1alpha alters subnuclear positioning of its genomic targets.

Luco RF, Maestro MA, Sadoni N, Zink D, Ferrer J.

PLoS Genet. 2008 May 23;4(5):e1000079. doi: 10.1371/journal.pgen.1000079.

39.

Influence of the suture in the propagation of tears in calf pericardium employed in the construction of cardiac bioprostheses.

Garcia Paez JM, Claramunt R, Millan I, Valdes M, Arriaga Y, Cordon A, Maestro MA, Rocha A, Refusta S, Ros A, Alvarez L, Jorge-Herrero E.

J Appl Biomater Biomech. 2008 Jan-Apr;6(1):55-62.

PMID:
20740447
40.

Synthesis of highly condensed polycyclic carbohydrates by reaction of a spirocyclic enamino sulfonate derived from d-xylofuranose with bifunctional reagents.

Cordeiro A, Jimeno ML, Maestro MA, Camarasa MJ, Quesada E, San-Félix A.

J Org Chem. 2007 Dec 7;72(25):9713-21. Epub 2007 Nov 14.

PMID:
17999530
41.

Distinct roles of HNF1beta, HNF1alpha, and HNF4alpha in regulating pancreas development, beta-cell function and growth.

Maestro MA, Cardalda C, Boj SF, Luco RF, Servitja JM, Ferrer J.

Endocr Dev. 2007;12:33-45. doi: 10.1159/000109603. Review.

PMID:
17923767
42.

Self-assembly of ligands designed for the building of a new type of [2 x 2] metallic grid. anion encapsulation and diffusion NMR spectroscopy.

Manzano BR, Jalón FA, Ortiz IM, Soriano ML, Torre FG, Elguero J, Maestro MA, Mereiter K, Claridge TD.

Inorg Chem. 2008 Jan 21;47(2):413-28. Epub 2007 Oct 2.

PMID:
17910436
43.
45.

Determination of the force necessary for the propagation of tears in ostrich and calf pericardium.

García Páez JM, Carrera A, Jorge E, Millán I, Cordón A, Maestro MA, Rocha A, Morales S, Castillo-Olivares JL.

J Biomed Mater Res B Appl Biomater. 2006 Nov;79(2):229-35.

PMID:
16637030
46.

The transcription factor hepatocyte nuclear factor-6 controls the development of pancreatic ducts in the mouse.

Pierreux CE, Poll AV, Kemp CR, Clotman F, Maestro MA, Cordi S, Ferrer J, Leyns L, Rousseau GG, Lemaigre FP.

Gastroenterology. 2006 Feb;130(2):532-41.

PMID:
16472605
47.
48.

Phosphine-substrate recognition through the C-H...O hydrogen bond: application to the asymmetric Pauson-Khand reaction.

Solà J, Riera A, Verdaguer X, Maestro MA.

J Am Chem Soc. 2005 Oct 5;127(39):13629-33. Erratum in: J Am Chem Soc. 2006 Oct 11;128(40):13312.

PMID:
16190728
49.

Oxazoline-mediated interannular cyclopalladation of ferrocene: chiral palladium(II) catalysts for the enantioselective Aza-Claisen rearrangement.

Moyano A, Rosol M, Moreno RM, López C, Maestro MA.

Angew Chem Int Ed Engl. 2005 Mar 11;44(12):1865-9. No abstract available.

PMID:
15723433
50.

Resistance and stability of a new method for bonding biological materials using sutures and biological adhesives.

Paéz JM, Sanmartín AC, Herrero EJ, Millan I, Cordon A, Rocha A, Maestro MA, Téllez G, Castillo-Olivares JL.

J Biomater Appl. 2005 Jan;19(3):215-36.

PMID:
15613381

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