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Items: 1 to 50 of 104

1.

Dissecting the Role of Thyrotropin in the DNA Damage Response in Human Thyrocytes after 131I, γ Radiation and H2O2.

Kyrilli A, Gacquer D, Detours V, Lefort A, Libert F, Twyffels L, Van Den Eeckhaute L, Strickaert A, Maenhaut C, De Deken X, Dumont JE, Miot F, Corvilain B.

J Clin Endocrinol Metab. 2020 Mar 1;105(3). pii: dgz185. doi: 10.1210/clinem/dgz185.

PMID:
31701151
2.

Class III PI3K Vps34 Controls Thyroid Hormone Production by Regulating Thyroglobulin Iodination, Lysosomal Proteolysis, and Tissue Homeostasis.

Grieco G, Wang T, Delcorte O, Spourquet C, Janssens V, Strickaert A, Gaide Chevronnay HP, Liao XH, Bilanges B, Refetoff S, Vanhaesebroeck B, Maenhaut C, Courtoy PJ, Pierreux CE.

Thyroid. 2020 Jan;30(1):133-146. doi: 10.1089/thy.2019.0182. Epub 2019 Dec 2.

PMID:
31650902
3.

Reprogramming of Energy Metabolism: Increased Expression and Roles of Pyruvate Carboxylase in Papillary Thyroid Cancer.

Strickaert A, Corbet C, Spinette SA, Craciun L, Dom G, Andry G, Larsimont D, Wattiez R, Dumont JE, Feron O, Maenhaut C.

Thyroid. 2019 Jun;29(6):845-857. doi: 10.1089/thy.2018.0435.

PMID:
30990120
4.

Thyroid follicular adenomas and carcinomas: molecular profiling provides evidence for a continuous evolution.

Dom G, Frank S, Floor S, Kehagias P, Libert F, Hoang C, Andry G, Spinette A, Craciun L, de Saint Aubin N, Tresallet C, Tissier F, Savagner F, Majjaj S, Gutierrez-Roelens I, Marbaix E, Dumont JE, Maenhaut C.

Oncotarget. 2017 Dec 8;9(12):10343-10359. doi: 10.18632/oncotarget.23130. eCollection 2018 Feb 13.

5.

Distinctive Desmoplastic 3D Morphology Associated With BRAFV600E in Papillary Thyroid Cancers.

Tarabichi M, Antoniou A, Le Pennec S, Gacquer D, de Saint Aubain N, Craciun L, Cielen T, Laios I, Larsimont D, Andry G, Dumont JE, Maenhaut C, Detours V.

J Clin Endocrinol Metab. 2018 Mar 1;103(3):1102-1111. doi: 10.1210/jc.2017-02279.

PMID:
29342254
6.

Cancer heterogeneity is not compatible with one unique cancer cell metabolic map.

Strickaert A, Saiselet M, Dom G, De Deken X, Dumont JE, Feron O, Sonveaux P, Maenhaut C.

Oncogene. 2017 May 11;36(19):2637-2642. doi: 10.1038/onc.2016.411. Epub 2016 Oct 31. Review.

7.

miRNA expression and function in thyroid carcinomas: a comparative and critical analysis and a model for other cancers.

Saiselet M, Pita JM, Augenlicht A, Dom G, Tarabichi M, Fimereli D, Dumont JE, Detours V, Maenhaut C.

Oncotarget. 2016 Aug 9;7(32):52475-52492. doi: 10.18632/oncotarget.9655. Review.

8.

ApolipoproteinL1 is expressed in papillary thyroid carcinomas.

Chidiac M, Fayyad-Kazan M, Daher J, Poelvoorde P, Bar I, Maenhaut C, Delrée P, Badran B, Vanhamme L.

Pathol Res Pract. 2016 Jul;212(7):631-5. doi: 10.1016/j.prp.2016.04.004. Epub 2016 Apr 24.

PMID:
27157405
9.

Gene signature of the post-Chernobyl papillary thyroid cancer.

Handkiewicz-Junak D, Swierniak M, Rusinek D, Oczko-Wojciechowska M, Dom G, Maenhaut C, Unger K, Detours V, Bogdanova T, Thomas G, Likhtarov I, Jaksik R, Kowalska M, Chmielik E, Jarzab M, Swierniak A, Jarzab B.

Eur J Nucl Med Mol Imaging. 2016 Jul;43(7):1267-77. doi: 10.1007/s00259-015-3303-3. Epub 2016 Jan 26.

10.

New global analysis of the microRNA transcriptome of primary tumors and lymph node metastases of papillary thyroid cancer.

Saiselet M, Gacquer D, Spinette A, Craciun L, Decaussin-Petrucci M, Andry G, Detours V, Maenhaut C.

BMC Genomics. 2015 Oct 21;16:828. doi: 10.1186/s12864-015-2082-3.

11.

Revisiting the transcriptional analysis of primary tumours and associated nodal metastases with enhanced biological and statistical controls: application to thyroid cancer.

Tarabichi M, Saiselet M, Trésallet C, Hoang C, Larsimont D, Andry G, Maenhaut C, Detours V.

Br J Cancer. 2015 May 12;112(10):1665-74. doi: 10.1038/bjc.2014.665.

12.

microRNA expression in autonomous thyroid adenomas: Correlation with mRNA regulation.

Floor SL, Trésallet C, Hébrant A, Desbuleux A, Libert F, Hoang C, Capello M, Andry G, van Staveren WC, Maenhaut C.

Mol Cell Endocrinol. 2015 Aug 15;411:1-10. doi: 10.1016/j.mce.2015.04.001. Epub 2015 Apr 23.

PMID:
25916957
13.

Ontogeny, Anatomy, Metabolism and Physiology of the Thyroid.

Maenhaut C, Christophe D, Vassart G, Dumont J, Roger PP, Opitz R.

In: Feingold KR, Anawalt B, Boyce A, Chrousos G, Dungan K, Grossman A, Hershman JM, Kaltsas G, Koch C, Kopp P, Korbonits M, McLachlan R, Morley JE, New M, Perreault L, Purnell J, Rebar R, Singer F, Trence DL, Vinik A, Wilson DP, editors. Endotext [Internet]. South Dartmouth (MA): MDText.com, Inc.; 2000-.
2015 Jul 15.

14.

Intratumor heterogeneity and clonal evolution in an aggressive papillary thyroid cancer and matched metastases.

Le Pennec S, Konopka T, Gacquer D, Fimereli D, Tarabichi M, Tomás G, Savagner F, Decaussin-Petrucci M, Trésallet C, Andry G, Larsimont D, Detours V, Maenhaut C.

Endocr Relat Cancer. 2015 Apr;22(2):205-16. doi: 10.1530/ERC-14-0351. Epub 2015 Feb 17.

PMID:
25691441
15.

MiRNA expression may account for chronic but not for acute regulation of mRNA expression in human thyroid tumor models.

Floor SL, Hebrant A, Pita JM, Saiselet M, Trésallet C, Libert F, Andry G, Dumont JE, van Staveren WC, Maenhaut C.

PLoS One. 2014 Nov 6;9(11):e111581. doi: 10.1371/journal.pone.0111581. eCollection 2014.

16.

miRNA expression in anaplastic thyroid carcinomas.

Hébrant A, Floor S, Saiselet M, Antoniou A, Desbuleux A, Snyers B, La C, de Saint Aubain N, Leteurtre E, Andry G, Maenhaut C.

PLoS One. 2014 Aug 25;9(8):e103871. doi: 10.1371/journal.pone.0103871. eCollection 2014.

17.

Cancer stem cells, a fuzzy evolving concept: a cell population or a cell property?

Antoniou A, Hébrant A, Dom G, Dumont JE, Maenhaut C.

Cell Cycle. 2013 Dec 15;12(24):3743-8. doi: 10.4161/cc.27305. Epub 2013 Nov 22. Review.

18.

Systems biology of cancer: entropy, disorder, and selection-driven evolution to independence, invasion and "swarm intelligence".

Tarabichi M, Antoniou A, Saiselet M, Pita JM, Andry G, Dumont JE, Detours V, Maenhaut C.

Cancer Metastasis Rev. 2013 Dec;32(3-4):403-21. doi: 10.1007/s10555-013-9431-y. Review.

19.

5-aza-2'-deoxycytidine has minor effects on differentiation in human thyroid cancer cell lines, but modulates genes that are involved in adaptation in vitro.

Dom G, Galdo VC, Tarabichi M, Tomás G, Hébrant A, Andry G, De Martelar V, Libert F, Leteurtre E, Dumont JE, Maenhaut C, van Staveren WC.

Thyroid. 2013 Mar;23(3):317-28. doi: 10.1089/thy.2012.0388.

20.

Thyroid cancer cell lines: an overview.

Saiselet M, Floor S, Tarabichi M, Dom G, Hébrant A, van Staveren WC, Maenhaut C.

Front Endocrinol (Lausanne). 2012 Nov 16;3:133. doi: 10.3389/fendo.2012.00133. eCollection 2012.

21.

mRNA expression in papillary and anaplastic thyroid carcinoma: molecular anatomy of a killing switch.

Hébrant A, Dom G, Dewaele M, Andry G, Trésallet C, Leteurtre E, Dumont JE, Maenhaut C.

PLoS One. 2012;7(10):e37807. doi: 10.1371/journal.pone.0037807. Epub 2012 Oct 24.

22.

A gene expression signature distinguishes normal tissues of sporadic and radiation-induced papillary thyroid carcinomas.

Dom G, Tarabichi M, Unger K, Thomas G, Oczko-Wojciechowska M, Bogdanova T, Jarzab B, Dumont JE, Detours V, Maenhaut C.

Br J Cancer. 2012 Sep 4;107(6):994-1000. doi: 10.1038/bjc.2012.302. Epub 2012 Jul 24.

23.

Hallmarks of cancer: of all cancer cells, all the time?

Floor SL, Dumont JE, Maenhaut C, Raspe E.

Trends Mol Med. 2012 Sep;18(9):509-15. doi: 10.1016/j.molmed.2012.06.005. Epub 2012 Jul 13.

PMID:
22795735
24.

A general method to derive robust organ-specific gene expression-based differentiation indices: application to thyroid cancer diagnostic.

Tomás G, Tarabichi M, Gacquer D, Hébrant A, Dom G, Dumont JE, Keutgen X, Fahey TJ 3rd, Maenhaut C, Detours V.

Oncogene. 2012 Oct 11;31(41):4490-8. doi: 10.1038/onc.2011.626. Epub 2012 Jan 23.

PMID:
22266856
25.

Role of Epac and protein kinase A in thyrotropin-induced gene expression in primary thyrocytes.

van Staveren WC, Beeckman S, Tomás G, Dom G, Hébrant A, Delys L, Vliem MJ, Trésallet C, Andry G, Franc B, Libert F, Dumont JE, Maenhaut C.

Exp Cell Res. 2012 Mar 10;318(5):444-52. doi: 10.1016/j.yexcr.2011.12.022. Epub 2012 Jan 4.

PMID:
22240166
26.

Cancer cells in epithelial-to-mesenchymal transition and tumor-propagating-cancer stem cells: distinct, overlapping or same populations.

Floor S, van Staveren WC, Larsimont D, Dumont JE, Maenhaut C.

Oncogene. 2011 Nov 17;30(46):4609-21. doi: 10.1038/onc.2011.184. Epub 2011 Jun 6. Review.

PMID:
21643013
27.

Gene expression profiles for radiation-induced thyroid cancer.

Maenhaut C, Detours V, Dom G, Handkiewicz-Junak D, Oczko-Wojciechowska M, Jarzab B.

Clin Oncol (R Coll Radiol). 2011 May;23(4):282-8. doi: 10.1016/j.clon.2011.01.509. Epub 2011 Mar 15. Review.

PMID:
21411301
28.

Genetic hyperthyroidism: hyperthyroidism due to activating TSHR mutations.

Hébrant A, van Staveren WC, Maenhaut C, Dumont JE, Leclère J.

Eur J Endocrinol. 2011 Jan;164(1):1-9. doi: 10.1530/EJE-10-0775. Epub 2010 Oct 6. Review.

PMID:
20926595
29.

Signal transduction in the human thyrocyte and its perversion in thyroid tumors.

Roger PP, van Staveren WC, Coulonval K, Dumont JE, Maenhaut C.

Mol Cell Endocrinol. 2010 May 28;321(1):3-19. doi: 10.1016/j.mce.2009.11.015. Epub 2009 Dec 3. Review.

PMID:
19962425
30.

Cancer stem cells: a reality, a myth, a fuzzy concept or a misnomer? An analysis.

Maenhaut C, Dumont JE, Roger PP, van Staveren WC.

Carcinogenesis. 2010 Feb;31(2):149-58. doi: 10.1093/carcin/bgp259. Epub 2009 Oct 25. Review.

PMID:
19858069
31.

Thyroid gene expression in familial nonautoimmune hyperthyroidism shows common characteristics with hyperfunctioning autonomous adenomas.

Hébrant A, Van Sande J, Roger PP, Patey M, Klein M, Bournaud C, Savagner F, Leclère J, Dumont JE, van Staveren WC, Maenhaut C.

J Clin Endocrinol Metab. 2009 Jul;94(7):2602-9. doi: 10.1210/jc.2008-2191. Epub 2009 Apr 21.

PMID:
19383781
32.

Human cancer cell lines: Experimental models for cancer cells in situ? For cancer stem cells?

van Staveren WC, Solís DY, Hébrant A, Detours V, Dumont JE, Maenhaut C.

Biochim Biophys Acta. 2009 Apr;1795(2):92-103. doi: 10.1016/j.bbcan.2008.12.004. Epub 2009 Jan 8. Review.

PMID:
19167460
33.

Gene expression profiles of post-Chernobyl thyroid cancers.

Detours V, Versteyhe S, Dumont JE, Maenhaut C.

Curr Opin Endocrinol Diabetes Obes. 2008 Oct;15(5):440-5. doi: 10.1097/MED.0b013e32830eb874. Review.

PMID:
18769217
34.

Human thyroid tumor cell lines derived from different tumor types present a common dedifferentiated phenotype.

van Staveren WC, Solís DW, Delys L, Duprez L, Andry G, Franc B, Thomas G, Libert F, Dumont JE, Detours V, Maenhaut C.

Cancer Res. 2007 Sep 1;67(17):8113-20.

35.

Genome-wide gene expression profiling suggests distinct radiation susceptibilities in sporadic and post-Chernobyl papillary thyroid cancers.

Detours V, Delys L, Libert F, Weiss Solís D, Bogdanova T, Dumont JE, Franc B, Thomas G, Maenhaut C.

Br J Cancer. 2007 Sep 17;97(6):818-25. Epub 2007 Aug 21.

36.

Long-term EGF/serum-treated human thyrocytes mimic papillary thyroid carcinomas with regard to gene expression.

Hébrant A, van Staveren WC, Delys L, Solís DW, Bogdanova T, Andry G, Roger P, Dumont JE, Libert F, Maenhaut C.

Exp Cell Res. 2007 Sep 10;313(15):3276-84. Epub 2007 Jul 4. Erratum in: Exp Cell Res. 2007 Nov 15;313(19):4082.

PMID:
17689531
37.

Roles of hydrogen peroxide in thyroid physiology and disease.

Song Y, Driessens N, Costa M, De Deken X, Detours V, Corvilain B, Maenhaut C, Miot F, Van Sande J, Many MC, Dumont JE.

J Clin Endocrinol Metab. 2007 Oct;92(10):3764-73. Epub 2007 Jul 31. Review.

PMID:
17666482
38.

Gene expression and the biological phenotype of papillary thyroid carcinomas.

Delys L, Detours V, Franc B, Thomas G, Bogdanova T, Tronko M, Libert F, Dumont JE, Maenhaut C.

Oncogene. 2007 Dec 13;26(57):7894-903. Epub 2007 Jul 9.

PMID:
17621275
39.

Cyclic adenosine 3',5'-monophosphate (cAMP)-dependent protein kinases, but not exchange proteins directly activated by cAMP (Epac), mediate thyrotropin/cAMP-dependent regulation of thyroid cells.

Dremier S, Milenkovic M, Blancquaert S, Dumont JE, Døskeland SO, Maenhaut C, Roger PP.

Endocrinology. 2007 Oct;148(10):4612-22. Epub 2007 Jun 21.

PMID:
17584967
40.

Negative feedbacks in normal cell growth and their suppression in tumorigenesis.

van Staveren WC, Detours V, Dumont JE, Maenhaut C.

Cell Cycle. 2006 Mar;5(6):571-2. Epub 2006 Mar 15. Review. No abstract available.

PMID:
16582620
41.

Gene expression in human thyrocytes and autonomous adenomas reveals suppression of negative feedbacks in tumorigenesis.

van Staveren WC, Solís DW, Delys L, Venet D, Cappello M, Andry G, Dumont JE, Libert F, Detours V, Maenhaut C.

Proc Natl Acad Sci U S A. 2006 Jan 10;103(2):413-8. Epub 2005 Dec 28.

42.

Identification of differentially expressed genes in thyrotropin stimulated dog thyroid cells by the cDNA-AFLP technique.

Vandeput F, Zabeau M, Maenhaut C.

Mol Cell Endocrinol. 2005 Nov 24;243(1-2):58-65. Epub 2005 Oct 11.

PMID:
16225984
43.
44.

[Gene expression profiling in human thyroid tumors].

Maenhaut C.

Bull Mem Acad R Med Belg. 2004;159(10-12):533-9; discussion 539-40. French.

PMID:
16035626
45.

Gene expression in thyroid autonomous adenomas provides insight into their physiopathology.

Wattel S, Mircescu H, Venet D, Burniat A, Franc B, Frank S, Andry G, Van Sande J, Rocmans P, Dumont JE, Detours V, Maenhaut C.

Oncogene. 2005 Oct 20;24(46):6902-16.

PMID:
16027733
46.

Absence of a specific radiation signature in post-Chernobyl thyroid cancers.

Detours V, Wattel S, Venet D, Hutsebaut N, Bogdanova T, Tronko MD, Dumont JE, Franc B, Thomas G, Maenhaut C.

Br J Cancer. 2005 Apr 25;92(8):1545-52.

47.

Normal thyroid structure and function in rhophilin 2-deficient mice.

Behrends J, Clément S, Pajak B, Pohl V, Maenhaut C, Dumont JE, Schurmans S.

Mol Cell Biol. 2005 Apr;25(7):2846-52.

48.

[Signal cascade involved in proliferation and differentiation of normal and neoplastic thyroid cells].

Maenhaut C.

Bull Mem Acad R Med Belg. 2004;159(5-6):389-95. French.

PMID:
15693549
49.

Search for new cyclic AMP-binding proteins.

Dremier S, Kopperud R, Doskeland SO, Dumont JE, Maenhaut C.

FEBS Lett. 2003 Jul 3;546(1):103-7. Review.

50.

Integration and cross-validation of high-throughput gene expression data: comparing heterogeneous data sets.

Detours V, Dumont JE, Bersini H, Maenhaut C.

FEBS Lett. 2003 Jul 3;546(1):98-102. Review.

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