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Items: 1 to 50 of 309

1.

Altered Hippocampal Epigenetic Regulation Underlying Reduced Cognitive Development in Response to Early Life Environmental Insults.

Schachtschneider KM, Welge ME, Auvil LS, Chaki S, Rund LA, Madsen O, Elmore MRP, Johnson RW, Groenen MAM, Schook LB.

Genes (Basel). 2020 Feb 4;11(2). pii: E162. doi: 10.3390/genes11020162.

2.

Impact of genotype, body weight and sex on the prenatal muscle transcriptome of Iberian pigs.

García-Contreras C, Madsen O, Groenen MAM, López-García A, Vázquez-Gómez M, Astiz S, Núñez Y, Benítez R, Fernández A, Isabel B, Rey AI, González-Bulnes A, Óvilo C.

PLoS One. 2020 Jan 28;15(1):e0227861. doi: 10.1371/journal.pone.0227861. eCollection 2020.

3.

Scoring magnetic resonance imaging (MRI) inflammation and structural lesions in sacroiliac joints of patients with axial spondyloarthritis: assessment of all MRI slices of the cartilaginous compartment versus standardized six or five slices.

Krabbe S, Kröber G, Pedersen SJ, Østergaard M, Møller JM, Sørensen IJ, Jensen B, Madsen OR, Klarlund M, Weber U.

Scand J Rheumatol. 2019 Dec 17:1-10. doi: 10.1080/03009742.2019.1675184. [Epub ahead of print]

PMID:
31847676
4.

High versus standard magnetic resonance image resolution of the cervical spine in patients with axial spondyloarthritis.

Krabbe S, Østergaard M, Sørensen IJ, Møller J, Jensen B, Madsen OR, Pedersen SJ.

Acta Radiol. 2019 Sep 3:284185119872689. doi: 10.1177/0284185119872689. [Epub ahead of print] No abstract available.

PMID:
31480852
5.

Genomic analysis on pygmy hog reveals extensive interbreeding during wild boar expansion.

Liu L, Bosse M, Megens HJ, Frantz LAF, Lee YL, Irving-Pease EK, Narayan G, Groenen MAM, Madsen O.

Nat Commun. 2019 Apr 30;10(1):1992. doi: 10.1038/s41467-019-10017-2.

6.

Whole-body Magnetic Resonance Imaging Inflammation in Peripheral Joints and Entheses in Axial Spondyloarthritis: Distribution and Changes during Adalimumab Treatment.

Krabbe S, Eshed I, Sørensen IJ, Jensen B, Møller JM, Balding L, Madsen OR, Pedersen SJ, Østergaard M.

J Rheumatol. 2020 Jan;47(1):50-58. doi: 10.3899/jrheum.181159. Epub 2019 Apr 1.

PMID:
30936290
7.

Effect of Magnetic Resonance Imaging vs Conventional Treat-to-Target Strategies on Disease Activity Remission and Radiographic Progression in Rheumatoid Arthritis: The IMAGINE-RA Randomized Clinical Trial.

Møller-Bisgaard S, Hørslev-Petersen K, Ejbjerg B, Hetland ML, Ørnbjerg LM, Glinatsi D, Møller J, Boesen M, Christensen R, Stengaard-Pedersen K, Madsen OR, Jensen B, Villadsen JA, Hauge EM, Bennett P, Hendricks O, Asmussen K, Kowalski M, Lindegaard H, Nielsen SM, Bliddal H, Krogh NS, Ellingsen T, Nielsen AH, Balding L, Jurik AG, Thomsen HS, Østergaard M.

JAMA. 2019 Feb 5;321(5):461-472. doi: 10.1001/jama.2018.21362.

8.

FRAX 10-yr Fracture Risk in Rheumatoid Arthritis-Assessments With and Without Bone Mineral Density May Lead to Very Different Results in the Individual Patient.

Elde KD, Madsen OR.

J Clin Densitom. 2019 Jan - Mar;22(1):31-38. doi: 10.1016/j.jocd.2018.10.007. Epub 2018 Oct 31.

PMID:
30497868
9.

Structural progression rate decreases over time on serial radiography and magnetic resonance imaging of sacroiliac joints and spine in a five-year follow-up study of patients with ankylosing spondylitis treated with tumour necrosis factor inhibitor.

Pedersen SJ, Weber U, Said-Nahal R, Sørensen IJ, Loft AG, Kollerup G, Juul L, Frandsen PB, Thamsborg G, Madsen OR, Møller J, Balding L, Jurik AG, Østergaard M.

Scand J Rheumatol. 2019 May;48(3):185-197. doi: 10.1080/03009742.2018.1506822. Epub 2018 Nov 13.

PMID:
30422733
10.

Balancing selection on a recessive lethal deletion with pleiotropic effects on two neighboring genes in the porcine genome.

Derks MFL, Lopes MS, Bosse M, Madsen O, Dibbits B, Harlizius B, Groenen MAM, Megens HJ.

PLoS Genet. 2018 Sep 19;14(9):e1007661. doi: 10.1371/journal.pgen.1007661. eCollection 2018 Sep.

11.

Evolutionary analysis of the carnitine- and choline acyltransferases suggests distinct evolution of CPT2 versus CPT1 and related variants.

van der Hoek MD, Madsen O, Keijer J, van der Leij FR.

Biochim Biophys Acta Mol Cell Biol Lipids. 2018 Aug;1863(8):909-918. doi: 10.1016/j.bbalip.2018.05.001. Epub 2018 May 4.

PMID:
29730527
12.

A nutritional intervention program improves the nutritional status of geriatric patients at nutritional risk-a randomized controlled trial.

Terp R, Jacobsen KO, Kannegaard P, Larsen AM, Madsen OR, Noiesen E.

Clin Rehabil. 2018 Jul;32(7):930-941. doi: 10.1177/0269215518765912. Epub 2018 Apr 2.

PMID:
29606025
13.

Inflammatory and structural changes in vertebral bodies and posterior elements of the spine in axial spondyloarthritis: construct validity, responsiveness and discriminatory ability of the anatomy-based CANDEN scoring system in a randomised placebo-controlled trial.

Krabbe S, Sørensen IJ, Jensen B, Møller JM, Balding L, Madsen OR, Lambert RGW, Maksymowych WP, Pedersen SJ, Østergaard M.

RMD Open. 2018 Mar 16;4(1):e000624. doi: 10.1136/rmdopen-2017-000624. eCollection 2018.

14.

Whole-body Magnetic Resonance Imaging in Axial Spondyloarthritis: Reduction of Sacroiliac, Spinal, and Entheseal Inflammation in a Placebo-controlled Trial of Adalimumab.

Krabbe S, Østergaard M, Eshed I, Sørensen IJ, Jensen B, Møller JM, Balding L, Madsen OR, Asmussen K, Eng G, Jørgensen NR, Pedersen SJ.

J Rheumatol. 2018 May;45(5):621-629. doi: 10.3899/jrheum.170408. Epub 2018 Feb 15.

PMID:
29449506
15.

The EndoC-βH1 cell line is a valid model of human beta cells and applicable for screenings to identify novel drug target candidates.

Tsonkova VG, Sand FW, Wolf XA, Grunnet LG, Kirstine Ringgaard A, Ingvorsen C, Winkel L, Kalisz M, Dalgaard K, Bruun C, Fels JJ, Helgstrand C, Hastrup S, Öberg FK, Vernet E, Sandrini MPB, Shaw AC, Jessen C, Grønborg M, Hald J, Willenbrock H, Madsen D, Wernersson R, Hansson L, Jensen JN, Plesner A, Alanentalo T, Petersen MBK, Grapin-Botton A, Honoré C, Ahnfelt-Rønne J, Hecksher-Sørensen J, Ravassard P, Madsen OD, Rescan C, Frogne T.

Mol Metab. 2018 Feb;8:144-157. doi: 10.1016/j.molmet.2017.12.007. Epub 2017 Dec 19.

17.

Gene networks for total number born in pigs across divergent environments.

Verardo LL, Lopes MS, Mathur P, Madsen O, Silva FF, Groenen MAM, Knol EF, Lopes PS, Guimarães SEF.

Mamm Genome. 2017 Oct;28(9-10):426-435. doi: 10.1007/s00335-017-9696-5. Epub 2017 Jun 2.

PMID:
28577119
18.

Oncopig Soft-Tissue Sarcomas Recapitulate Key Transcriptional Features of Human Sarcomas.

Schachtschneider KM, Liu Y, Mäkeläinen S, Madsen O, Rund LA, Groenen MAM, Schook LB.

Sci Rep. 2017 Jun 1;7(1):2624. doi: 10.1038/s41598-017-02912-9.

19.

[Rheumatoid arthritis and hand surgery].

Peretz AS, Madsen OR, Brogren E, Dahlin L, Søe NH.

Ugeskr Laeger. 2017 Mar 13;179(11). pii: V09160677. Review. Danish.

PMID:
28330532
20.

The Importance of Endophenotypes to Evaluate the Relationship between Genotype and External Phenotype.

Te Pas MF, Madsen O, Calus MP, Smits MA.

Int J Mol Sci. 2017 Feb 22;18(2). pii: E472. doi: 10.3390/ijms18020472. Review.

21.

Pancreatic α-cell hyperplasia and hyperglucagonemia due to a glucagon receptor splice mutation.

Larger E, Wewer Albrechtsen NJ, Hansen LH, Gelling RW, Capeau J, Deacon CF, Madsen OD, Yakushiji F, De Meyts P, Holst JJ, Nishimura E.

Endocrinol Diabetes Metab Case Rep. 2016;2016. pii: 16-0081. Epub 2016 Nov 21.

22.

Long-Term GABA Administration Induces Alpha Cell-Mediated Beta-like Cell Neogenesis.

Ben-Othman N, Vieira A, Courtney M, Record F, Gjernes E, Avolio F, Hadzic B, Druelle N, Napolitano T, Navarro-Sanz S, Silvano S, Al-Hasani K, Pfeifer A, Lacas-Gervais S, Leuckx G, Marroquí L, Thévenet J, Madsen OD, Eizirik DL, Heimberg H, Kerr-Conte J, Pattou F, Mansouri A, Collombat P.

Cell. 2017 Jan 12;168(1-2):73-85.e11. doi: 10.1016/j.cell.2016.11.002. Epub 2016 Dec 1.

23.

Social norms as solutions.

Nyborg K, Anderies JM, Dannenberg A, Lindahl T, Schill C, Schlüter M, Adger WN, Arrow KJ, Barrett S, Carpenter S, Chapin FS 3rd, Crépin AS, Daily G, Ehrlich P, Folke C, Jager W, Kautsky N, Levin SA, Madsen OJ, Polasky S, Scheffer M, Walker B, Weber EU, Wilen J, Xepapadeas A, de Zeeuw A.

Science. 2016 Oct 7;354(6308):42-43. No abstract available.

PMID:
27846488
24.

Impact of neonatal iron deficiency on hippocampal DNA methylation and gene transcription in a porcine biomedical model of cognitive development.

Schachtschneider KM, Liu Y, Rund LA, Madsen O, Johnson RW, Groenen MA, Schook LB.

BMC Genomics. 2016 Nov 3;17(1):856.

25.

Investigation of a multi-biomarker disease activity score in rheumatoid arthritis by comparison with magnetic resonance imaging, computed tomography, ultrasonography, and radiography parameters of inflammation and damage.

Krabbe S, Bolce R, Brahe CH, Døhn UM, Ejbjerg BJ, Hetland ML, Sasso EH, Chernoff D, Hansen MS, Knudsen LS, Hansen A, Madsen OR, Hasselquist M, Møller J, Østergaard M.

Scand J Rheumatol. 2017 Sep;46(5):353-358. doi: 10.1080/03009742.2016.1211315. Epub 2016 Sep 28.

PMID:
27682742
26.

Revisiting the immunocytochemical detection of Neurogenin 3 expression in mouse and man.

Honoré C, Rescan C, Hald J, McGrath PS, Petersen MB, Hansson M, Klein T, Østergaard S, Wells JM, Madsen OD.

Diabetes Obes Metab. 2016 Sep;18 Suppl 1:10-22. doi: 10.1111/dom.12718. Review.

PMID:
27615127
27.
28.

Stability of clinical outcome measures in rheumatoid arthritis patients with stable disease defined on the basis of the EULAR response criteria.

Madsen OR.

Clin Rheumatol. 2016 Oct;35(10):2403-9. doi: 10.1007/s10067-016-3322-x. Epub 2016 Jun 9.

PMID:
27283868
29.

A tree of geese: A phylogenomic perspective on the evolutionary history of True Geese.

Ottenburghs J, Megens HJ, Kraus RHS, Madsen O, van Hooft P, van Wieren SE, Crooijmans RPMA, Ydenberg RC, Groenen MAM, Prins HHT.

Mol Phylogenet Evol. 2016 Aug;101:303-313. doi: 10.1016/j.ympev.2016.05.021. Epub 2016 May 24.

PMID:
27233434
30.

Gene and transposable element methylation in great tit (Parus major) brain and blood.

Derks MF, Schachtschneider KM, Madsen O, Schijlen E, Verhoeven KJ, van Oers K.

BMC Genomics. 2016 May 4;17:332. doi: 10.1186/s12864-016-2653-y.

31.

After genome-wide association studies: Gene networks elucidating candidate genes divergences for number of teats across two pig populations.

Verardo LL, Lopes MS, Wijga S, Madsen O, Silva FF, Groenen MA, Knol EF, Lopes PS, Guimarães SE.

J Anim Sci. 2016 Apr;94(4):1446-58. doi: 10.2527/jas.2015-9917.

PMID:
27136004
32.

The Use of Genomics in Conservation Management of the Endangered Visayan Warty Pig (Sus cebifrons).

Nuijten RJ, Bosse M, Crooijmans RP, Madsen O, Schaftenaar W, Ryder OA, Groenen MA, Megens HJ.

Int J Genomics. 2016;2016:5613862. doi: 10.1155/2016/5613862. Epub 2016 Mar 16.

33.

Risk of virus-associated cancer in female arthritis patients treated with biological DMARDs-a cohort study.

Cordtz R, Mellemkjær L, Glintborg B, Hetland ML, Madsen OR, Jensen Hansen IM, Dreyer L.

Rheumatology (Oxford). 2016 Jun;55(6):1017-22. doi: 10.1093/rheumatology/kew012. Epub 2016 Feb 24.

PMID:
26912584
34.

Establishment of age- and sex-adjusted reference data for hand bone mass and investigation of hand bone loss in patients with rheumatoid arthritis treated in clinical practice: an observational study from the DANBIO registry and the Copenhagen Osteoarthritis Study.

Ørnbjerg LM, Østergaard M, Jensen T, Hyldstrup L, Bach-Mortensen P, Bøyesen P, Thormann A, Tarp U, Bøhme WP, Lindegaard H, Poulsen UE, Schlemmer A, Graudal N, Rødgaard A, Espesen J, Kollerup GB, Glintborg B, Madsen OR, Jensen DV, Hetland ML.

Arthritis Res Ther. 2016 Feb 24;18:53. doi: 10.1186/s13075-016-0952-y.

35.

Xenotropic retrovirus Bxv1 in human pancreatic β cell lines.

Kirkegaard JS, Ravassard P, Ingvarsen S, Diedisheim M, Bricout-Neveu E, Grønborg M, Frogne T, Scharfmann R, Madsen OD, Rescan C, Albagli O.

J Clin Invest. 2016 Mar 1;126(3):1109-13. doi: 10.1172/JCI83573. Epub 2016 Feb 22.

36.

Revealing new candidate genes for reproductive traits in pigs: combining Bayesian GWAS and functional pathways.

Verardo LL, Silva FF, Lopes MS, Madsen O, Bastiaansen JW, Knol EF, Kelly M, Varona L, Lopes PS, Guimarães SE.

Genet Sel Evol. 2016 Feb 1;48:9. doi: 10.1186/s12711-016-0189-x.

37.

Evolutionary signals of selection on cognition from the great tit genome and methylome.

Laine VN, Gossmann TI, Schachtschneider KM, Garroway CJ, Madsen O, Verhoeven KJ, de Jager V, Megens HJ, Warren WC, Minx P, Crooijmans RP, Corcoran P; Great Tit HapMap Consortium, Sheldon BC, Slate J, Zeng K, van Oers K, Visser ME, Groenen MA.

Nat Commun. 2016 Jan 25;7:10474. doi: 10.1038/ncomms10474.

38.

Artificial selection on introduced Asian haplotypes shaped the genetic architecture in European commercial pigs.

Bosse M, Lopes MS, Madsen O, Megens HJ, Crooijmans RP, Frantz LA, Harlizius B, Bastiaansen JW, Groenen MA.

Proc Biol Sci. 2015 Dec 22;282(1821):20152019. doi: 10.1098/rspb.2015.2019.

39.

Research Resource: A Dual Proteomic Approach Identifies Regulated Islet Proteins During β-Cell Mass Expansion In Vivo.

Horn S, Kirkegaard JS, Hoelper S, Seymour PA, Rescan C, Nielsen JH, Madsen OD, Jensen JN, Krüger M, Grønborg M, Ahnfelt-Rønne J.

Mol Endocrinol. 2016 Jan;30(1):133-43. doi: 10.1210/me.2015-1208. Epub 2015 Dec 9.

40.

Adult porcine genome-wide DNA methylation patterns support pigs as a biomedical model.

Schachtschneider KM, Madsen O, Park C, Rund LA, Groenen MA, Schook LB.

BMC Genomics. 2015 Oct 5;16:743. doi: 10.1186/s12864-015-1938-x.

41.

Autocrine Action of IGF2 Regulates Adult β-Cell Mass and Function.

Modi H, Jacovetti C, Tarussio D, Metref S, Madsen OD, Zhang FP, Rantakari P, Poutanen M, Nef S, Gorman T, Regazzi R, Thorens B.

Diabetes. 2015 Dec;64(12):4148-57. doi: 10.2337/db14-1735. Epub 2015 Sep 17.

42.

Evidence of long-term gene flow and selection during domestication from analyses of Eurasian wild and domestic pig genomes.

Frantz LA, Schraiber JG, Madsen O, Megens HJ, Cagan A, Bosse M, Paudel Y, Crooijmans RP, Larson G, Groenen MA.

Nat Genet. 2015 Oct;47(10):1141-8. doi: 10.1038/ng.3394. Epub 2015 Aug 31.

PMID:
26323058
43.

Discordance of Global Assessments by Patient and Physician Is Higher in Female than in Male Patients Regardless of the Physician's Sex: Data on Patients with Rheumatoid Arthritis, Axial Spondyloarthritis, and Psoriatic Arthritis from the DANBIO Registry.

Lindström Egholm C, Krogh NS, Pincus T, Dreyer L, Ellingsen T, Glintborg B, Kowalski MR, Lorenzen T, Madsen OR, Nordin H, Rasmussen C, Hetland ML.

J Rheumatol. 2015 Oct;42(10):1781-5. doi: 10.3899/jrheum.150007. Epub 2015 Aug 1.

PMID:
26233511
44.

Analysis artefacts of the INS-IGF2 fusion transcript.

Wernersson R, Frogne T, Rescan C, Hansson L, Bruun C, Grønborg M, Jensen JN, Madsen OD.

BMC Mol Biol. 2015 Jul 29;16:13. doi: 10.1186/s12867-015-0042-8.

45.

Using genome-wide measures of coancestry to maintain diversity and fitness in endangered and domestic pig populations.

Bosse M, Megens HJ, Madsen O, Crooijmans RP, Ryder OA, Austerlitz F, Groenen MA, de Cara MA.

Genome Res. 2015 Jul;25(7):970-81. doi: 10.1101/gr.187039.114. Epub 2015 Jun 10.

46.

Interplay between patient global assessment, pain, and fatigue and influence of other clinical disease activity measures in patients with active rheumatoid arthritis.

Egsmose EL, Madsen OR.

Clin Rheumatol. 2015 Jul;34(7):1187-94. doi: 10.1007/s10067-015-2968-0. Epub 2015 May 19.

PMID:
25986917
47.

Copy number variation in the speciation of pigs: a possible prominent role for olfactory receptors.

Paudel Y, Madsen O, Megens HJ, Frantz LA, Bosse M, Crooijmans RP, Groenen MA.

BMC Genomics. 2015 Apr 22;16:330. doi: 10.1186/s12864-015-1449-9.

48.

Evolution of Tibetan wild boars.

Frantz LA, Madsen O, Megens HJ, Schraiber JG, Paudel Y, Bosse M, Crooijmans RP, Larson G, Groenen MA.

Nat Genet. 2015 Mar;47(3):188-9. doi: 10.1038/ng.3197. No abstract available.

49.

Hybrid origin of European commercial pigs examined by an in-depth haplotype analysis on chromosome 1.

Bosse M, Madsen O, Megens HJ, Frantz LA, Paudel Y, Crooijmans RP, Groenen MA.

Front Genet. 2015 Jan 5;5:442. doi: 10.3389/fgene.2014.00442. eCollection 2014.

50.

Influence of field strength, coil type and image resolution on assessment of synovitis by unenhanced MRI--a comparison with contrast-enhanced MRI.

Eshed I, Krabbe S, Østergaard M, Bøyesen P, Møller JM, Therkildsen F, Madsen OR, Axelsen M, Pedersen SJ.

Eur Radiol. 2015 Apr;25(4):1059-67. doi: 10.1007/s00330-014-3470-9. Epub 2014 Dec 24.

PMID:
25537977

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