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Items: 1 to 50 of 190

1.

Topographic modeling of early human osteoarthritis in sheep.

Oláh T, Reinhard J, Gao L, Haberkamp S, Goebel LKH, Cucchiarini M, Madry H.

Sci Transl Med. 2019 Sep 4;11(508). pii: eaax6775. doi: 10.1126/scitranslmed.aax6775.

PMID:
31484789
2.

Life is a journey.

Madry H.

J Exp Orthop. 2019 Jul 11;6(1):34. doi: 10.1186/s40634-019-0202-8. No abstract available.

3.

Therapeutic Effects of rAAV-Mediated Concomittant Gene Transfer and Overexpression of TGF-β and IGF-I on the Chondrogenesis of Human Bone-Marrow-Derived Mesenchymal Stem Cells.

Morscheid S, Rey-Rico A, Schmitt G, Madry H, Cucchiarini M, Venkatesan JK.

Int J Mol Sci. 2019 May 27;20(10). pii: E2591. doi: 10.3390/ijms20102591.

4.

An overview of thermal necrosis: present and future.

Mediouni M, Kucklick T, Poncet S, Madiouni R, Abouaomar A, Madry H, Cucchiarini M, Chopko B, Vaughan N, Arora M, Gökkuş K, Lozoya Lara M, Paiva Cedeño L, Volosnikov A, Hesmati M, Ho K.

Curr Med Res Opin. 2019 May 10:1-8. doi: 10.1080/03007995.2019.1603671. [Epub ahead of print]

PMID:
30943796
5.

Advances in modern osteotomies around the knee : Report on the Association of Sports Traumatology, Arthroscopy, Orthopaedic surgery, Rehabilitation (ASTAOR) Moscow International Osteotomy Congress 2017.

Gao L, Madry H, Chugaev DV, Denti M, Frolov A, Burtsev M, Magnitskaya N, Mukhanov V, Neyret P, Solomin LN, Sorokin E, Staubli AE, Stone KR, Vilenskiy V, Zayats V, Pape D, Korolev A.

J Exp Orthop. 2019 Feb 25;6(1):9. doi: 10.1186/s40634-019-0177-5. Review.

6.

[Future Aspects of Clinical Osteoarthritis Therapies in the Continuum of Translational Research].

Schrenker S, Gao L, Cucchiarini M, Madry H.

Z Orthop Unfall. 2019 Feb 6. doi: 10.1055/a-0806-8225. [Epub ahead of print] German.

PMID:
30727008
7.

Microfracture for cartilage repair in the knee: a systematic review of the contemporary literature.

Orth P, Gao L, Madry H.

Knee Surg Sports Traumatol Arthrosc. 2019 Jan 18. doi: 10.1007/s00167-019-05359-9. [Epub ahead of print]

PMID:
30659314
8.

Biomaterial-guided delivery of gene vectors for targeted articular cartilage repair.

Cucchiarini M, Madry H.

Nat Rev Rheumatol. 2019 Jan;15(1):18-29. doi: 10.1038/s41584-018-0125-2. Review.

PMID:
30514957
9.

Current trends in tendinopathy: consensus of the ESSKA basic science committee. Part II: treatment options.

Abat F, Alfredson H, Cucchiarini M, Madry H, Marmotti A, Mouton C, Oliveira JM, Pereira H, Peretti GM, Spang C, Stephen J, van Bergen CJA, de Girolamo L.

J Exp Orthop. 2018 Sep 24;5(1):38. doi: 10.1186/s40634-018-0145-5. Review.

10.

Asymptomatic focal calcium pyrophosphate crystal deposition within partially failed repair tissue after matrix-assisted autologous chondrocyte implantation.

Gao L, Oláh T, Cucchiarini M, Madry H.

Knee Surg Sports Traumatol Arthrosc. 2019 Jun;27(6):1939-1942. doi: 10.1007/s00167-018-5136-7. Epub 2018 Sep 10.

PMID:
30203199
11.

Improved Chondrogenic Differentiation of rAAV SOX9-Modified Human MSCs Seeded in Fibrin-Polyurethane Scaffolds in a Hydrodynamic Environment.

Venkatesan JK, Gardner O, Rey-Rico A, Eglin D, Alini M, Stoddart MJ, Cucchiarini M, Madry H.

Int J Mol Sci. 2018 Sep 5;19(9). pii: E2635. doi: 10.3390/ijms19092635.

12.

Itaconic acid indicates cellular but not systemic immune system activation.

Meiser J, Kraemer L, Jaeger C, Madry H, Link A, Lepper PM, Hiller K, Schneider JG.

Oncotarget. 2018 Aug 14;9(63):32098-32107. doi: 10.18632/oncotarget.25956. eCollection 2018 Aug 14.

13.

Kongresszusammenfassung – AFOR 2018.

Schrenker S, Madry H.

Z Orthop Unfall. 2018 Aug;156(4):378-380. doi: 10.1055/a-0635-8824. Epub 2018 Aug 24. German. No abstract available.

PMID:
30142684
14.

[Correction: Significance of Matrix-augmented Bone Marrow Stimulation for Treatment of Cartilage Defects of the Knee: A Consensus Statement of the DGOU Working Group on Tissue Regeneration].

Niemeyer P, Becher C, Brucker PU, Buhs M, Fickert S, Gelse K, Günther D, Kaelin R, Kreuz P, Lützner J, Nehrer S, Madry H, Marlovits S, Mehl J, Ott H, Pietschmann M, Spahn G, Tischer T, Volz M, Walther M, Welsch G, Zellner J, Zinser W, Angele P.

Z Orthop Unfall. 2018 Aug 24. doi: 10.1055/a-0670-5638. [Epub ahead of print] German. No abstract available.

PMID:
30142636
15.

[Significance of Matrix-augmented Bone Marrow Stimulation for Treatment of Cartilage Defects of the Knee: A Consensus Statement of the DGOU Working Group on Tissue Regeneration].

Niemeyer P, Becher C, Brucker PU, Buhs M, Fickert S, Gelse K, Günther D, Kaelin R, Kreuz P, Lützner J, Nehrer S, Madry H, Marlovits S, Mehl J, Ott H, Pietschmann M, Spahn G, Tischer T, Volz M, Walther M, Welsch G, Zellner J, Zinser W, Angele P.

Z Orthop Unfall. 2018 Oct;156(5):513-532. doi: 10.1055/a-0591-6457. Epub 2018 Jun 18. Review. German.

PMID:
29913540
16.

Effects of TGF-β Overexpression via rAAV Gene Transfer on the Early Repair Processes in an Osteochondral Defect Model in Minipigs.

Cucchiarini M, Asen AK, Goebel L, Venkatesan JK, Schmitt G, Zurakowski D, Menger MD, Laschke MW, Madry H.

Am J Sports Med. 2018 Jul;46(8):1987-1996. doi: 10.1177/0363546518773709. Epub 2018 May 24.

PMID:
29792508
17.

[Correction: Debridement in Focal Cartilage Damage of the knee. Systematical review of the literature and recommendations of the working group "clinical tissue regeneration" of the German Society of Orthopaedics and Trauma (DGOU)].

Gelse K, Angele P, Behrens P, Bruckner PU, Fay J, Günther D, Kreuz P, Lützner J, Madry H, Müller PE, Niemeyer P, Pagenstert G, Tischer T, Walther M, Zinser W, Spahn G.

Z Orthop Unfall. 2018 May 17. doi: 10.1055/a-0630-6590. [Epub ahead of print] German. No abstract available.

PMID:
29772583
18.

Effective Remodelling of Human Osteoarthritic Cartilage by sox9 Gene Transfer and Overexpression upon Delivery of rAAV Vectors in Polymeric Micelles.

Rey-Rico A, Venkatesan JK, Schmitt G, Speicher-Mentges S, Madry H, Cucchiarini M.

Mol Pharm. 2018 Jul 2;15(7):2816-2826. doi: 10.1021/acs.molpharmaceut.8b00331. Epub 2018 May 24.

PMID:
29763553
19.

Subchondral drilling for articular cartilage repair: a systematic review of translational research.

Gao L, Goebel LKH, Orth P, Cucchiarini M, Madry H.

Dis Model Mech. 2018 Jun 19;11(6). pii: dmm034280. doi: 10.1242/dmm.034280. Review.

20.

Chondrogenic Differentiation Processes in Human Bone-Marrow Aspirates Seeded in Three-Dimensional-Woven Poly(ɛ-Caprolactone) Scaffolds Enhanced by Recombinant Adeno-Associated Virus-Mediated SOX9 Gene Transfer.

Venkatesan JK, Moutos FT, Rey-Rico A, Estes BT, Frisch J, Schmitt G, Madry H, Guilak F, Cucchiarini M.

Hum Gene Ther. 2018 Nov;29(11):1277-1286. doi: 10.1089/hum.2017.165. Epub 2018 Jun 11.

PMID:
29717624
21.

Sustained spatiotemporal release of TGF-β1 confers enhanced very early chondrogenic differentiation during osteochondral repair in specific topographic patterns.

Asen AK, Goebel L, Rey-Rico A, Sohier J, Zurakowski D, Cucchiarini M, Madry H.

FASEB J. 2018 Oct;32(10):5298-5311. doi: 10.1096/fj.201800105R. Epub 2018 Apr 24.

PMID:
29688810
22.

[Debridement in Focal Cartilage Damage of the knee. Systematical review of the literature and recommendations of the working group "clinical tissue regeneration" of the German Society of Orthopaedics and Trauma (DGOU)].

Gelse K, Angele P, Behrens P, Brucker PU, Fay J, Günther D, Kreuz P, Lützner J, Madry H, Müller PE, Niemeyer P, Pagenstert G, Tischer T, Walther M, Zinser W, Spahn G.

Z Orthop Unfall. 2018 Aug;156(4):423-435. doi: 10.1055/s-0044-101470. Epub 2018 Mar 9. Review. German.

PMID:
29523016
23.

Reliable landmarks for precise topographical analyses of pathological structural changes of the ovine tibial plateau in 2-D and 3-D subspaces.

Oláh T, Reinhard J, Gao L, Goebel LKH, Madry H.

Sci Rep. 2018 Jan 8;8(1):75. doi: 10.1038/s41598-017-18426-3.

24.

Autologous Matrix-Induced Chondrogenesis: A Systematic Review of the Clinical Evidence.

Gao L, Orth P, Cucchiarini M, Madry H.

Am J Sports Med. 2019 Jan;47(1):222-231. doi: 10.1177/0363546517740575. Epub 2017 Nov 21.

PMID:
29161138
25.

rAAV-mediated overexpression of TGF-β via vector delivery in polymeric micelles stimulates the biological and reparative activities of human articular chondrocytes in vitro and in a human osteochondral defect model.

Rey-Rico A, Venkatesan JK, Schmitt G, Concheiro A, Madry H, Alvarez-Lorenzo C, Cucchiarini M.

Int J Nanomedicine. 2017 Sep 19;12:6985-6996. doi: 10.2147/IJN.S144579. eCollection 2017.

26.

A review of translational medicine. The future paradigm: how can we connect the orthopedic dots better?

Mediouni M, R Schlatterer D, Madry H, Cucchiarini M, Rai B.

Curr Med Res Opin. 2018 Jul;34(7):1217-1229. doi: 10.1080/03007995.2017.1385450. Epub 2017 Nov 1.

PMID:
28952378
27.

Erratum zu: Die Meniskusläsion – ein präarthrotischer Zustand des Kniegelenks.

Goebel L, Reinhard J, Madry H.

Orthopade. 2017 Oct;46(10):854. doi: 10.1007/s00132-017-3476-5. German. No abstract available.

PMID:
28936595
28.

[Biologic Reconstruction of Full Sized Cartilage Defects of the Hip: A Guideline from the DGOU Group "Clinical Tissue Regeneration" and the Hip Committee of the AGA].

Fickert S, Aurich M, Albrecht D, Angele P, Büchler L, Dienst M, Erggelet C, Fritz J, Gebhart C, Gollwitzer H, Kindler M, Lampert C, Madry H, Möckel G, Niemeyer P, Schröder J, Sobau C, Spahn G, Zinser W, Landgraeber S.

Z Orthop Unfall. 2017 Dec;155(6):670-682. doi: 10.1055/s-0043-116218. Epub 2017 Sep 15. Review. German.

PMID:
28915523
29.

[Meniscal lesion. A pre-osteoarthritic condition of the knee joint].

Goebel L, Reinhard J, Madry H.

Orthopade. 2017 Oct;46(10):822-830. doi: 10.1007/s00132-017-3462-y. Review. German. Erratum in: Orthopade. 2017 Oct;46(10 ):854.

PMID:
28852795
30.

Effects of solid acellular type-I/III collagen biomaterials on in vitro and in vivo chondrogenesis of mesenchymal stem cells.

Gao L, Orth P, Cucchiarini M, Madry H.

Expert Rev Med Devices. 2017 Sep;14(9):717-732. doi: 10.1080/17434440.2017.1368386.

PMID:
28817971
31.

IGF-1 Gene Transfer to Human Synovial MSCs Promotes Their Chondrogenic Differentiation Potential without Induction of the Hypertrophic Phenotype.

Ikeda Y, Sakaue M, Chijimatsu R, Hart DA, Otsubo H, Shimomura K, Madry H, Suzuki T, Yoshikawa H, Yamashita T, Nakamura N.

Stem Cells Int. 2017;2017:5804147. doi: 10.1155/2017/5804147. Epub 2017 Jun 27.

32.

Impact of mechanical stimulation on the chondrogenic processes in human bone marrow aspirates modified to overexpress sox9 via rAAV vectors.

Venkatesan JK, Frisch J, Rey-Rico A, Schmitt G, Madry H, Cucchiarini M.

J Exp Orthop. 2017 Dec;4(1):22. doi: 10.1186/s40634-017-0097-1. Epub 2017 Jun 21.

33.

Bone Marrow Aspirate Concentrate-Enhanced Marrow Stimulation of Chondral Defects.

Madry H, Gao L, Eichler H, Orth P, Cucchiarini M.

Stem Cells Int. 2017;2017:1609685. doi: 10.1155/2017/1609685. Epub 2017 May 14. Review.

34.

Current trends in tendinopathy: consensus of the ESSKA basic science committee. Part I: biology, biomechanics, anatomy and an exercise-based approach.

Abat F, Alfredson H, Cucchiarini M, Madry H, Marmotti A, Mouton C, Oliveira JM, Pereira H, Peretti GM, Romero-Rodriguez D, Spang C, Stephen J, van Bergen CJA, de Girolamo L.

J Exp Orthop. 2017 Dec;4(1):18. doi: 10.1186/s40634-017-0092-6. Epub 2017 May 30. Review.

35.

Supramolecular polypseudorotaxane gels for controlled delivery of rAAV vectors in human mesenchymal stem cells for regenerative medicine.

Rey-Rico A, Babicz H, Madry H, Concheiro A, Alvarez-Lorenzo C, Cucchiarini M.

Int J Pharm. 2017 Oct 15;531(2):492-503. doi: 10.1016/j.ijpharm.2017.05.050. Epub 2017 May 25.

PMID:
28552768
36.

Peripheral blood aspirates overexpressing IGF-I via rAAV gene transfer undergo enhanced chondrogenic differentiation processes.

Frisch J, Orth P, Rey-Rico A, Venkatesan JK, Schmitt G, Madry H, Kohn D, Cucchiarini M.

J Cell Mol Med. 2017 Nov;21(11):2748-2758. doi: 10.1111/jcmm.13190. Epub 2017 May 3.

37.

A retinaculum-sparing surgical approach preserves porcine stifle joint cartilage in an experimental animal model of cartilage repair.

Bonadio MB, Friedman JM, Sennett ML, Mauck RL, Dodge GR, Madry H.

J Exp Orthop. 2017 Dec;4(1):11. doi: 10.1186/s40634-017-0083-7. Epub 2017 Apr 17.

38.

Comparison of Fixation Techniques of 3D-Woven Poly(ϵ-Caprolactone) Scaffolds for Cartilage Repair in a Weightbearing Porcine Large Animal Model.

Friedman JM, Sennett ML, Bonadio MB, Orji KO, Neuwirth AL, Keah N, Carey JL, Moutos FT, Estes BT, Guilak F, Madry H, Mauck RL, Dodge GR.

Cartilage. 2018 Oct;9(4):428-437. doi: 10.1177/1947603517700953. Epub 2017 Apr 11.

39.

Early loss of subchondral bone following microfracture is counteracted by bone marrow aspirate in a translational model of osteochondral repair.

Gao L, Orth P, Müller-Brandt K, Goebel LK, Cucchiarini M, Madry H.

Sci Rep. 2017 Mar 27;7:45189. doi: 10.1038/srep45189.

40.

Effects of combined rAAV-mediated TGF-β and sox9 gene transfer and overexpression on the metabolic and chondrogenic activities in human bone marrow aspirates.

Tao K, Rey-Rico A, Frisch J, Venkatesan JK, Schmitt G, Madry H, Lin J, Cucchiarini M.

J Exp Orthop. 2017 Dec;4(1):4. doi: 10.1186/s40634-017-0077-5. Epub 2017 Feb 7.

41.

Genetic Modification of Human Peripheral Blood Aspirates Using Recombinant Adeno-Associated Viral Vectors for Articular Cartilage Repair with a Focus on Chondrogenic Transforming Growth Factor-β Gene Delivery.

Frisch J, Orth P, Venkatesan JK, Rey-Rico A, Schmitt G, Kohn D, Madry H, Cucchiarini M.

Stem Cells Transl Med. 2017 Jan;6(1):249-260. doi: 10.5966/sctm.2016-0149. Epub 2016 Aug 29.

42.

Hydrogels for precision meniscus tissue engineering: a comprehensive review.

Rey-Rico A, Cucchiarini M, Madry H.

Connect Tissue Res. 2017 May - Jul;58(3-4):317-328. doi: 10.1080/03008207.2016.1276576. Epub 2017 Jan 4. Review.

PMID:
28051883
43.

Macroscopic cartilage repair scoring of defect fill, integration and total points correlate with corresponding items in histological scoring systems - a study in adult sheep.

Goebel L, Orth P, Cucchiarini M, Pape D, Madry H.

Osteoarthritis Cartilage. 2017 Apr;25(4):581-588. doi: 10.1016/j.joca.2016.10.014. Epub 2016 Oct 24.

44.

Hydrogel-Based Controlled Delivery Systems for Articular Cartilage Repair.

Rey-Rico A, Madry H, Cucchiarini M.

Biomed Res Int. 2016;2016:1215263. doi: 10.1155/2016/1215263. Epub 2016 Aug 23.

45.

A novel algorithm for a precise analysis of subchondral bone alterations.

Gao L, Orth P, Goebel LK, Cucchiarini M, Madry H.

Sci Rep. 2016 Sep 6;6:32982. doi: 10.1038/srep32982.

46.

Effects of rAAV-mediated FGF-2 gene transfer and overexpression upon the chondrogenic differentiation processes in human bone marrow aspirates.

Frisch J, Venkatesan JK, Rey-Rico A, Zawada AM, Schmitt G, Madry H, Cucchiarini M.

J Exp Orthop. 2016 Dec;3(1):16. doi: 10.1186/s40634-016-0052-6. Epub 2016 Jul 29.

47.

Biological Reconstruction of the Osteochondral Unit After Failed Focal Resurfacing of a Chondral Defect in the Knee.

Goebel L, Kohn D, Madry H.

Am J Sports Med. 2016 Nov;44(11):2911-2916. Epub 2016 Jul 13. No abstract available.

PMID:
27411359
48.

PEO-PPO-PEO Carriers for rAAV-Mediated Transduction of Human Articular Chondrocytes in Vitro and in a Human Osteochondral Defect Model.

Rey-Rico A, Frisch J, Venkatesan JK, Schmitt G, Rial-Hermida I, Taboada P, Concheiro A, Madry H, Alvarez-Lorenzo C, Cucchiarini M.

ACS Appl Mater Interfaces. 2016 Aug 17;8(32):20600-13. doi: 10.1021/acsami.6b06509. Epub 2016 Aug 3.

PMID:
27404480
49.
50.

Surgical anatomy of medial open-wedge high tibial osteotomy: crucial steps and pitfalls.

Madry H, Goebel L, Hoffmann A, Dück K, Gerich T, Seil R, Tschernig T, Pape D.

Knee Surg Sports Traumatol Arthrosc. 2017 Dec;25(12):3661-3669. doi: 10.1007/s00167-016-4181-3. Epub 2016 May 28.

PMID:
27236541

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