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Items: 35

1.

Cofactor-mediated amyloidogenesis.

Madine J.

Biosci Rep. 2019 Mar 6;39(3). pii: BSR20190327. doi: 10.1042/BSR20190327. Print 2019 Mar 29.

2.

Isolation and purification of recombinant immunoglobulin light chain variable domains from the periplasmic space of Escherichia coli.

Hand K, Wilkinson MC, Madine J.

PLoS One. 2018 Oct 22;13(10):e0206167. doi: 10.1371/journal.pone.0206167. eCollection 2018.

3.

Human cerebral collateral arteriole function in subjects with normal cognition, mild cognitive impairment, and dementia.

Migrino RQ, Truran S, Karamanova N, Serrano GE, Madrigal C, Davies HA, Madine J, Reaven P, Beach TG.

Am J Physiol Heart Circ Physiol. 2018 Aug 1;315(2):H284-H290. doi: 10.1152/ajpheart.00206.2018. Epub 2018 May 18.

PMID:
29775413
4.

Insights into the Origin of Distinct Medin Fibril Morphologies Induced by Incubation Conditions and Seeding.

Davies HA, Lee CF, Miller L, Liu LN, Madine J.

Int J Mol Sci. 2018 May 3;19(5). pii: E1357. doi: 10.3390/ijms19051357.

5.

Using an NMR metabolomics approach to investigate the pathogenicity of amyloid-beta and alpha-synuclein.

Phelan MM, Caamaño-Gutiérrez E, Gant MS, Grosman RX, Madine J.

Metabolomics. 2017;13(12):151. doi: 10.1007/s11306-017-1289-5. Epub 2017 Oct 29.

6.

Effect of amino acid mutations on the conformational dynamics of amyloidogenic immunoglobulin light-chains: A combined NMR and in silico study.

Mukherjee S, Pondaven SP, Hand K, Madine J, Jaroniec CP.

Sci Rep. 2017 Sep 4;7(1):10339. doi: 10.1038/s41598-017-10906-w.

7.

Amyloidogenic medin induces endothelial dysfunction and vascular inflammation through the receptor for advanced glycation endproducts.

Migrino RQ, Davies HA, Truran S, Karamanova N, Franco DA, Beach TG, Serrano GE, Truong D, Nikkhah M, Madine J.

Cardiovasc Res. 2017 Sep 1;113(11):1389-1402. doi: 10.1093/cvr/cvx135.

PMID:
28859297
8.
9.

Heparin and Methionine Oxidation Promote the Formation of Apolipoprotein A-I Amyloid Comprising α-Helical and β-Sheet Structures.

Townsend D, Hughes E, Hussain R, Siligardi G, Baldock S, Madine J, Middleton DA.

Biochemistry. 2017 Mar 21;56(11):1632-1644. doi: 10.1021/acs.biochem.6b01120. Epub 2017 Mar 13.

PMID:
27992182
10.

Nanoliposomes protect against human arteriole endothelial dysfunction induced by β-amyloid peptide.

Truran S, Weissig V, Madine J, Davies HA, Guzman-Villanueva D, Franco DA, Karamanova N, Burciu C, Serrano G, Beach TG, Migrino RQ.

J Cereb Blood Flow Metab. 2016 Feb;36(2):405-12. doi: 10.1177/0271678X15610134. Epub 2015 Oct 8.

11.

Oxidative Stress Alters the Morphology and Toxicity of Aortic Medial Amyloid.

Davies HA, Phelan MM, Wilkinson MC, Migrino RQ, Truran S, Franco DA, Liu LN, Longmore CJ, Madine J.

Biophys J. 2015 Dec 1;109(11):2363-70. doi: 10.1016/j.bpj.2015.10.034.

12.

1H, 15N and 13C assignment of the amyloidogenic protein medin using fast-pulsing NMR techniques.

Davies HA, Phelan MM, Madine J.

Biomol NMR Assign. 2016 Apr;10(1):75-7. doi: 10.1007/s12104-015-9641-z. Epub 2015 Sep 16.

13.

Comparisons with amyloid-β reveal an aspartate residue that stabilizes fibrils of the aortic amyloid peptide medin.

Davies HA, Madine J, Middleton DA.

J Biol Chem. 2015 Mar 20;290(12):7791-803. doi: 10.1074/jbc.M114.602177. Epub 2015 Jan 22.

14.

Heparin promotes the rapid fibrillization of a peptide with low intrinsic amyloidogenicity.

Madine J, Davies HA, Hughes E, Middleton DA.

Biochemistry. 2013 Dec 17;52(50):8984-92. doi: 10.1021/bi401231u. Epub 2013 Dec 6.

PMID:
24279288
15.

Insights into the molecular architecture of a peptide nanotube using FTIR and solid-state NMR spectroscopic measurements on an aligned sample.

Middleton DA, Madine J, Castelletto V, Hamley IW.

Angew Chem Int Ed Engl. 2013 Sep 27;52(40):10537-40. doi: 10.1002/anie.201301960. Epub 2013 Aug 16.

16.

Site-specific identification of an aβ fibril-heparin interaction site by using solid-state NMR spectroscopy.

Madine J, Pandya MJ, Hicks MR, Rodger A, Yates EA, Radford SE, Middleton DA.

Angew Chem Int Ed Engl. 2012 Dec 21;51(52):13140-3. doi: 10.1002/anie.201204459. Epub 2012 Nov 14.

17.

Fibrils and nanotubes assembled from a modified amyloid-β peptide fragment differ in the packing of the same β-sheet building blocks.

Madine J, Davies HA, Shaw C, Hamley IW, Middleton DA.

Chem Commun (Camb). 2012 Mar 21;48(24):2976-8. doi: 10.1039/c2cc17118j. Epub 2012 Feb 13.

PMID:
22328992
18.

Solid-state NMR reveals differences in the packing arrangements of peptide aggregates derived from the aortic amyloid polypeptide medin.

Davies HA, Madine J, Middleton DA.

J Pept Sci. 2012 Jan;18(1):65-72. doi: 10.1002/psc.1418. Epub 2011 Nov 21.

PMID:
22102261
19.

Measurement of multiple torsional angles from one-dimensional solid-state NMR spectra: application to the conformational analysis of a ligand in its biological receptor site.

Edwards R, Madine J, Fielding L, Middleton DA.

Phys Chem Chem Phys. 2010 Nov 14;12(42):13999-4008. doi: 10.1039/c0cp00326c. Epub 2010 Sep 28.

PMID:
20877838
20.

Comparison of aggregation enhancement and inhibition as strategies for reducing the cytotoxicity of the aortic amyloid polypeptide medin.

Madine J, Middleton DA.

Eur Biophys J. 2010 Aug;39(9):1281-8. doi: 10.1007/s00249-010-0581-3. Epub 2010 Feb 17.

PMID:
20162269
21.

Inhibitors of protein aggregation and toxicity.

Amijee H, Madine J, Middleton DA, Doig AJ.

Biochem Soc Trans. 2009 Aug;37(Pt 4):692-6. doi: 10.1042/BST0370692. Review.

PMID:
19614577
22.

Evaluation of beta-alanine- and GABA-substituted peptides as inhibitors of disease-linked protein aggregation.

Madine J, Wang X, Brown DR, Middleton DA.

Chembiochem. 2009 Aug 17;10(12):1982-7. doi: 10.1002/cbic.200900219. No abstract available.

PMID:
19591188
23.

Exploiting a (13)C-labelled heparin analogue for in situ solid-state NMR investigations of peptide-glycan interactions within amyloid fibrils.

Madine J, Clayton JC, Yates EA, Middleton DA.

Org Biomol Chem. 2009 Jun 7;7(11):2414-20. doi: 10.1039/b820808e. Epub 2009 Mar 31.

PMID:
19462052
24.

Cross-beta spine architecture of fibrils formed by the amyloidogenic segment NFGSVQFV of medin from solid-state NMR and X-ray fiber diffraction measurements.

Madine J, Copland A, Serpell LC, Middleton DA.

Biochemistry. 2009 Apr 14;48(14):3089-99. doi: 10.1021/bi802164e.

PMID:
19196164
25.

The effects of alpha-synuclein on phospholipid vesicle integrity: a study using 31P NMR and electron microscopy.

Madine J, Hughes E, Doig AJ, Middleton DA.

Mol Membr Biol. 2008 Sep;25(6-7):518-27. doi: 10.1080/09687680802467977.

PMID:
18949627
26.

Structural insights into the polymorphism of amyloid-like fibrils formed by region 20-29 of amylin revealed by solid-state NMR and X-ray fiber diffraction.

Madine J, Jack E, Stockley PG, Radford SE, Serpell LC, Middleton DA.

J Am Chem Soc. 2008 Nov 12;130(45):14990-5001. doi: 10.1021/ja802483d. Epub 2008 Oct 21.

PMID:
18937465
27.

Design of an N-methylated peptide inhibitor of alpha-synuclein aggregation guided by solid-state NMR.

Madine J, Doig AJ, Middleton DA.

J Am Chem Soc. 2008 Jun 25;130(25):7873-81. doi: 10.1021/ja075356q. Epub 2008 May 30.

28.
29.

An NMR strategy for obtaining multiple conformational constraints for 15N-13C spin-pair labelled organic solids.

Madine J, Middleton DA.

Phys Chem Chem Phys. 2006 Nov 28;8(44):5223-8. Epub 2006 Oct 10.

PMID:
17203146
30.

A study of the regional effects of alpha-synuclein on the organization and stability of phospholipid bilayers.

Madine J, Doig AJ, Middleton DA.

Biochemistry. 2006 May 9;45(18):5783-92.

PMID:
16669622
31.

Studies of the aggregation of an amyloidogenic alpha-synuclein peptide fragment.

Madine J, Doig AJ, Kitmitto A, Middleton DA.

Biochem Soc Trans. 2005 Nov;33(Pt 5):1113-5.

PMID:
16246058
32.

The aggregation and membrane-binding properties of an alpha-synuclein peptide fragment.

Madine J, Doig AJ, Middleton DA.

Biochem Soc Trans. 2004 Dec;32(Pt 6):1127-9.

PMID:
15506987
34.

Cyclization/hydrosilylation of functionalized 1,6-diynes catalyzed by cationic platinum complexes containing bidentate nitrogen ligands.

Wang X, Chakrapani H, Madine JW, Keyerleber MA, Widenhoefer RA.

J Org Chem. 2002 May 3;67(9):2778-88.

PMID:
11975528
35.

Cyclization/hydrosilylation of functionalized diynes catalyzed by a cationic platinum phenanthroline complex.

Madine JW, Wang X, Widenhoefer RA.

Org Lett. 2001 Feb 8;3(3):385-8. Erratum in: Org Lett 2001 May 17;3(10):1591.

PMID:
11428020

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