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Computer-aided diagnosis for World Health Organization-defined chest radiograph primary-endpoint pneumonia in children.

Mahomed N, van Ginneken B, Philipsen RHHM, Melendez J, Moore DP, Moodley H, Sewchuran T, Mathew D, Madhi SA.

Pediatr Radiol. 2020 Jan 13. doi: 10.1007/s00247-019-04593-0. [Epub ahead of print]


Immunogenicity and safety of different dosing schedules of trivalent inactivated influenza vaccine in pregnant women with HIV: a randomised controlled trial.

Nunes MC, Cutland CL, Moultrie A, Jones S, Ortiz JR, Neuzil KM, Klugman KP, Simões EAF, Weinberg A, Madhi SA; Maternal Flu Trial Team.

Lancet HIV. 2020 Jan 3. pii: S2352-3018(19)30322-4. doi: 10.1016/S2352-3018(19)30322-4. [Epub ahead of print]


Evaluation of the impact of HIV-1 infection and density of common nasopharyngeal bacterial colonizers in South African children immunized with 7-valent pneumococcal conjugate vaccine.

Olwagen CP, Adrian PV, Madhi SA.

Vaccine. 2019 Dec 21. pii: S0264-410X(19)31675-5. doi: 10.1016/j.vaccine.2019.12.033. [Epub ahead of print]


Rubella seroprevalence in pregnant women living with and without HIV in Soweto, South Africa.

Gieles NC, Mutsaerts EAML, Kwatra G, Bont L, Cutland CL, Jones S, Moultrie A, Madhi SA, Nunes MC.

Int J Infect Dis. 2019 Dec 19;91:255-260. doi: 10.1016/j.ijid.2019.12.018. [Epub ahead of print]


A mosaic tetracycline resistance gene tet(S/M) detected in an MDR pneumococcal CC230 lineage that underwent capsular switching in South Africa.

Lo SW, Gladstone RA, van Tonder AJ, Du Plessis M, Cornick JE, Hawkins PA, Madhi SA, Nzenze SA, Kandasamy R, Ravikumar KL, Elmdaghri N, Kwambana-Adams B, Almeida SCG, Skoczynska A, Egorova E, Titov L, Saha SK, Paragi M, Everett DB, Antonio M, Klugman KP, Li Y, Metcalf BJ, Beall B, McGee L, Breiman RF, Bentley SD, von Gottberg A; Global Pneumococcal Sequencing Consortium .

J Antimicrob Chemother. 2019 Dec 2. pii: dkz477. doi: 10.1093/jac/dkz477. [Epub ahead of print]


Measles seroprevalence in pregnant women in Soweto, South Africa: a nested cohort study.

Gieles NC, Mutsaerts EAML, Kwatra G, Bont L, Cutland CL, Jones S, Moultrie A, Madhi SA, Nunes MC.

Clin Microbiol Infect. 2019 Nov 13. pii: S1198-743X(19)30604-4. doi: 10.1016/j.cmi.2019.11.006. [Epub ahead of print]


Vaccinology in sub-Saharan Africa.

Moïsi J, Madhi SA, Rees H.

BMJ Glob Health. 2019 Sep 20;4(5):e001363. doi: 10.1136/bmjgh-2018-001363. eCollection 2019. Review.


Maternal and neonatal vitamin D status at birth in black South Africans.

Velaphi SC, Izu A, Madhi SA, Pettifor JM.

S Afr Med J. 2019 Sep 30;109(10):807-813. doi: 10.7196/SAMJ.2019.v109i10.13651.


Genomic differences among carriage and invasive nontypeable pneumococci circulating in South Africa.

Mohale T, Wolter N, Allam M, Nzenze SA, Madhi SA, du Plessis M, von Gottberg A.

Microb Genom. 2019 Oct;5(10). doi: 10.1099/mgen.0.000299. Epub 2019 Oct 11.


Clinical and Molecular Epidemiology of Invasive Group B Streptococcus Disease among Infants, China.

Ji W, Liu H, Madhi SA, Cunnington M, Zhang Z, Dangor Z, Zhou H, Mu X, Jin Z, Wang A, Qin X, Gao C, Zhu Y, Feng X, She S, Yang S, Liu J, Lei J, Jiang L, Liu Z, Li G, Li Q, Deng Q, Gao K, Fang Y.

Emerg Infect Dis. 2019 Nov;25(11):2021-2030. doi: 10.3201/eid2511.181647.


Using Participatory Workshops to Assess Alignment or Tension in the Community for Minimally Invasive Tissue Sampling Prior to Start of Child Mortality Surveillance: Lessons From 5 Sites Across the CHAMPS Network.

Blevins J, O'Mara Sage E, Kone A, Maixenchs M, Raghunathan PL, Guilaze RA, Cossa S, Girma Z, Zegeye Y, Ackley C, Hussain F, Islam S, Myburgh N, Ngwenya N, Madhi SA, Otieno P, Ochola K, Munguambe K, Breiman RF.

Clin Infect Dis. 2019 Oct 9;69(Supplement_4):S280-S290. doi: 10.1093/cid/ciz563.


Mortality Surveillance Methods to Identify and Characterize Deaths in Child Health and Mortality Prevention Surveillance Network Sites.

Salzberg NT, Sivalogan K, Bassat Q, Taylor AW, Adedini S, El Arifeen S, Assefa N, Blau DM, Chawana R, Cain CJ, Cain KP, Caneer JP, Garel M, Gurley ES, Kaiser R, Kotloff KL, Mandomando I, Morris T, Nyamthimba Onyango P, Sazzad HMS, Scott JAG, Seale AC, Sitoe A, Sow SO, Tapia MD, Whitney EA, Worrell MC, Zielinski-Gutierrez E, Madhi SA, Raghunathan PL, Koplan JP, Breiman RF; Child Health and Mortality Prevention Surveillance (CHAMPS) Methods Consortium .

Clin Infect Dis. 2019 Oct 9;69(Supplement_4):S262-S273. doi: 10.1093/cid/ciz599.


Health and Demographic Surveillance Systems Within the Child Health and Mortality Prevention Surveillance Network.

Cunningham SA, Shaikh NI, Nhacolo A, Raghunathan PL, Kotloff K, Naser AM, Mengesha MM, Adedini SA, Misore T, Onuwchekwa UU, Worrell MC, El Arifeen S, Assefa N, Chowdhury AI, Kaiser R, Madhi SA, Mehta A, Obor D, Sacoor C, Sow SO, Tapia MD, Wilkinson AL, Breiman RF.

Clin Infect Dis. 2019 Oct 9;69(Supplement_4):S274-S279. doi: 10.1093/cid/ciz609.


Overview and Development of the Child Health and Mortality Prevention Surveillance Determination of Cause of Death (DeCoDe) Process and DeCoDe Diagnosis Standards.

Blau DM, Caneer JP, Philipsborn RP, Madhi SA, Bassat Q, Varo R, Mandomando I, Igunza KA, Kotloff KL, Tapia MD, Johnstone S, Chawana R, Rahman A, El Arifeen S, Onyango D, Kaiser R, Seale AC, Assefa N, Morris T, Raghunathan PL, Breiman RF.

Clin Infect Dis. 2019 Oct 9;69(Supplement_4):S333-S341. doi: 10.1093/cid/ciz572.


Unraveling Specific Causes of Neonatal Mortality Using Minimally Invasive Tissue Sampling: An Observational Study.

Madhi SA, Pathirana J, Baillie V, Izu A, Bassat Q, Blau DM, Breiman RF, Hale M, Mathunjwa A, Martines RB, Nakwa FL, Nzenze S, Ordi J, Raghunathan PL, Ritter JM, Solomon F, Velaphi S, Wadula J, Zaki SR, Chawana R.

Clin Infect Dis. 2019 Oct 9;69(Supplement_4):S351-S360. doi: 10.1093/cid/ciz574.


Potential of Minimally Invasive Tissue Sampling for Attributing Specific Causes of Childhood Deaths in South Africa: A Pilot, Epidemiological Study.

Chawana R, Baillie V, Izu A, Solomon F, Bassat Q, Blau DM, Breiman RF, Hale M, Houpt ER, Lala SG, Martines RB, Mathunjwa A, Nzenze S, Pathirana J, Petersen KL, Raghunathan PL, Ritter JM, Wadula J, Zaki SR, Madhi SA.

Clin Infect Dis. 2019 Oct 9;69(Supplement_4):S361-S373. doi: 10.1093/cid/ciz550.


Illuminating Child Mortality: Discovering Why Children Die.

Raghunathan PL, Madhi SA, Breiman RF.

Clin Infect Dis. 2019 Oct 9;69(Supplement_4):S257-S259. doi: 10.1093/cid/ciz562.


Investigating the Feasibility of Child Mortality Surveillance With Postmortem Tissue Sampling: Generating Constructs and Variables to Strengthen Validity and Reliability in Qualitative Research.

O'Mara Sage E, Munguambe KR, Blevins J, Guilaze R, Kosia B, Maixenchs M, Bassat Q, Mandomando I, Kaiser R, Kone A, Jambai A, Myburgh ND, Ngwenya N, Madhi SA, Degefa K, Ackley C, Breiman RF, Raghunathan PL.

Clin Infect Dis. 2019 Oct 9;69(Supplement_4):S291-S301. doi: 10.1093/cid/ciz564.


An Observational Pilot Study Evaluating the Utility of Minimally Invasive Tissue Sampling to Determine the Cause of Stillbirths in South African Women.

Madhi SA, Pathirana J, Baillie V, Cutland C, Adam Y, Izu A, Bassat Q, Blau DM, Breiman RF, Hale M, Johnstone S, Martines RB, Mathunjwa A, Nzenze S, Ordi J, Raghunathan PL, Ritter JM, Solomon F, Wadula J, Zaki SR, Chawana R.

Clin Infect Dis. 2019 Oct 9;69(Supplement_4):S342-S350. doi: 10.1093/cid/ciz573.


Influenza and tuberculosis co-infection: A systematic review.

Walaza S, Cohen C, Tempia S, Moyes J, Nguweneza A, Madhi SA, McMorrow M, Cohen AL.

Influenza Other Respir Viruses. 2020 Jan;14(1):77-91. doi: 10.1111/irv.12670. Epub 2019 Sep 30.


Hemagglutinin-stalk antibody responses following trivalent inactivated influenza vaccine immunization of pregnant women and association with protection from influenza virus illness.

Dhar N, Kwatra G, Nunes MC, Cutland C, Izu A, Nachbagauer R, Krammer F, Madhi SA.

Clin Infect Dis. 2019 Sep 27. pii: ciz927. doi: 10.1093/cid/ciz927. [Epub ahead of print]


Placental Transfer of Respiratory Syncytial Virus Antibody Among HIV-Exposed, Uninfected Infants.

Patel SM, Jallow S, Boiditswe S, Madhi SA, Feemster KA, Steenhoff AP, Arscott-Mills T, Muthoga C, Ajibola G, Shapiro R, Shah SS, Cunningham CK, Kelly MS.

J Pediatric Infect Dis Soc. 2019 Sep 24. pii: piz056. doi: 10.1093/jpids/piz056. [Epub ahead of print]


The ferroportin Q248H mutation protects from anemia, but not malaria or bacteremia.

Muriuki JM, Mentzer AJ, Band G, Gilchrist JJ, Carstensen T, Lule SA, Goheen MM, Joof F, Kimita W, Mogire R, Cutland CL, Diarra A, Rautanen A, Pomilla C, Gurdasani D, Rockett K, Mturi N, Ndungu FM, Scott JAG, Sirima SB, Morovat A, Prentice AM, Madhi SA, Webb EL, Elliott AM, Bejon P, Sandhu MS, Hill AVS, Kwiatkowski DP, Williams TN, Cerami C, Atkinson SH.

Sci Adv. 2019 Sep 4;5(9):eaaw0109. doi: 10.1126/sciadv.aaw0109. eCollection 2019 Sep.


Trivalent influenza vaccination randomized control trial of pregnant women and adverse fetal outcomes.

Simões EAF, Nunes MC, Carosone-Link P, Madimabe R, Ortiz JR, Neuzil KM, Klugman KP, Cutland CL, Madhi SA; Matflu Team.

Vaccine. 2019 Aug 23;37(36):5397-5403. doi: 10.1016/j.vaccine.2019.07.024. Epub 2019 Jul 19.


Vaccines for maternal immunization against Group B Streptococcus disease: WHO perspectives on case ascertainment and case definitions.

Seale AC, Baker CJ, Berkley JA, Madhi SA, Ordi J, Saha SK, Schrag SJ, Sobanjo-Ter Meulen A, Vekemans J.

Vaccine. 2019 Aug 14;37(35):4877-4885. doi: 10.1016/j.vaccine.2019.07.012. Epub 2019 Jul 11. Review.


Global patterns in monthly activity of influenza virus, respiratory syncytial virus, parainfluenza virus, and metapneumovirus: a systematic analysis.

Li Y, Reeves RM, Wang X, Bassat Q, Brooks WA, Cohen C, Moore DP, Nunes M, Rath B, Campbell H, Nair H; RSV Global Epidemiology Network; RESCEU investigators.

Lancet Glob Health. 2019 Aug;7(8):e1031-e1045. doi: 10.1016/S2214-109X(19)30264-5.


Immunogenicity and Safety of an Early Measles Vaccination Schedule at 6 and 12 Months of Age in Human Immunodeficiency Virus (HIV)-Unexposed and HIV-Exposed, Uninfected South African Children.

Mutsaerts EAML, Nunes MC, Bhikha S, Ikulinda BT, Boyce W, Jose L, Koen A, Moultrie A, Cutland CL, Grobbee DE, Klipstein-Grobusch K, Madhi SA.

J Infect Dis. 2019 Sep 26;220(9):1529-1538. doi: 10.1093/infdis/jiz348.


Molecular Subtyping of Human Rhinovirus in Children from Three Sub-Saharan African Countries.

Baillie VL, Moore DP, Mathunjwa A, Morailane P, Simões EAF, Madhi SA.

J Clin Microbiol. 2019 Aug 26;57(9). pii: e00723-19. doi: 10.1128/JCM.00723-19. Print 2019 Sep.


Causes of severe pneumonia requiring hospital admission in children without HIV infection from Africa and Asia: the PERCH multi-country case-control study.

Pneumonia Etiology Research for Child Health (PERCH) Study Group.

Lancet. 2019 Aug 31;394(10200):757-779. doi: 10.1016/S0140-6736(19)30721-4. Epub 2019 Jun 27. Erratum in: Lancet. 2019 Aug 31;394(10200):736.


Efficacy and effectiveness of ten-valent versus 13-valent pneumococcal conjugate vaccines - Authors' reply.

Goldblatt D, Madhi SA.

Lancet Infect Dis. 2019 Jul;19(7):693-694. doi: 10.1016/S1473-3099(19)30286-5. No abstract available.


Pneumococcal lineages associated with serotype replacement and antibiotic resistance in childhood invasive pneumococcal disease in the post-PCV13 era: an international whole-genome sequencing study.

Lo SW, Gladstone RA, van Tonder AJ, Lees JA, du Plessis M, Benisty R, Givon-Lavi N, Hawkins PA, Cornick JE, Kwambana-Adams B, Law PY, Ho PL, Antonio M, Everett DB, Dagan R, von Gottberg A, Klugman KP, McGee L, Breiman RF, Bentley SD; Global Pneumococcal Sequencing Consortium.

Lancet Infect Dis. 2019 Jul;19(7):759-769. doi: 10.1016/S1473-3099(19)30297-X. Epub 2019 Jun 10.


Immunogenicity of a combined schedule of trivalent oral and inactivated polio vaccines in South African infants.

Moonsamy S, Suchard MS, Madhi SA.

Expert Rev Vaccines. 2019 Jul;18(7):751-754. doi: 10.1080/14760584.2019.1627878. Epub 2019 Jun 13.


Safety and Immunogenicity of Measles Vaccination in HIV-Infected and HIV-Exposed Uninfected Children: A Systematic Review and Meta-Analysis.

Mutsaerts EAML, Nunes MC, van Rijswijk MN, Klipstein-Grobusch K, Grobbee DE, Madhi SA.

EClinicalMedicine. 2018 Jul 2;1:28-42. doi: 10.1016/j.eclinm.2018.06.002. eCollection 2018 Jul.


Putative novel cps loci in a large global collection of pneumococci.

van Tonder AJ, Gladstone RA, Lo SW, Nahm MH, du Plessis M, Cornick J, Kwambana-Adams B, Madhi SA, Hawkins PA, Benisty R, Dagan R, Everett D, Antonio M, Klugman KP, von Gottberg A, Breiman RF, McGee L, Bentley SD, The Global Pneumococcal Sequencing Consortium.

Microb Genom. 2019 Jul;5(7). doi: 10.1099/mgen.0.000274. Epub 2019 Jun 11.


Optimal timing of influenza vaccine during pregnancy: A systematic review and meta-analysis.

Cuningham W, Geard N, Fielding JE, Braat S, Madhi SA, Nunes MC, Christian LM, Lin SY, Lee CN, Yamaguchi K, Bisgaard H, Chawes B, Chao AS, Blanchard-Rohner G, Schlaudecker EP, Fisher BM, McVernon J, Moss R.

Influenza Other Respir Viruses. 2019 Sep;13(5):438-452. doi: 10.1111/irv.12649. Epub 2019 Jun 5. Review.


Epidemiology of invasive bacterial infections in pneumococcal conjugate vaccine-vaccinated and -unvaccinated children under 5 years of age in Soweto, South Africa: a cohort study from a high-HIV burden setting.

Johnstone SL, Moore DP, Klugman KP, Madhi SA, Groome MJ.

Paediatr Int Child Health. 2019 Jun 3:1-8. doi: 10.1080/20469047.2019.1623572. [Epub ahead of print]


South Africa's first national vaccination coverage survey since 1994.

Burnett RJ, Dlamini NR, Meyer JC, Mutevedzi P, Kibuuka DK, Mphahlele MJ, Madhi SA.

S Afr Med J. 2019 Apr 29;109(5):12611. doi: 10.7196/SAMJ.2019.v109i5.14020. No abstract available.


Evaluation of intussusception after oral monovalent rotavirus vaccination in South Africa.

Groome MJ, Tate JE, Arnold M, Chitnis M, Cox S, de Vos C, Kirsten M, le Grange SM, Loveland J, Machaea S, Maharaj A, Andrews N, Madhi SA, Parashar UD.

Clin Infect Dis. 2019 May 24. pii: ciz431. doi: 10.1093/cid/ciz431. [Epub ahead of print]


The predictive performance of a pneumonia severity score in HIV-negative children presenting to hospital in seven low and middle-income countries.

Gallagher KE, Knoll MD, Prosperi C, Baggett HC, Brooks WA, Feiken DR, Hammitt LL, Howie SRC, Kotloff KL, Levine OS, Madhi SA, Murdoch DR, O'Brien KL, Thea DM, Awori JO, Baillie VL, Ebruke BE, Goswami D, Kamau A, Maloney SA, Moore DP, Mwananyanda L, Olutunde EO, Seidenberg P, Sissoko S, Sylla M, Thamthitiwat S, Zaman K, Scott JAG; PERCH Study Group.

Clin Infect Dis. 2019 May 6. pii: ciz350. doi: 10.1093/cid/ciz350. [Epub ahead of print]


The association between breastmilk group B Streptococcal capsular antibody levels and late-onset disease in young infants.

Dangor Z, Khan M, Kwatra G, Izu A, Nakwa F, Ramdin T, Fredericks J, Lala SG, Madhi SA.

Clin Infect Dis. 2019 May 6. pii: ciz360. doi: 10.1093/cid/ciz360. [Epub ahead of print]


Influenza epidemiology and influenza vaccine effectiveness during the 2016-2017 season in the Global Influenza Hospital Surveillance Network (GIHSN).

Baselga-Moreno V, Trushakova S, McNeil S, Sominina A, Nunes MC, Draganescu A, Unal S, Koul P, Kyncl J, Zhang T, Kuatbayeva A, Ben-Salah A, Burtseva E, Puig-Barberà J, Díez-Domingo J; Global Influenza Hospital Surveillance Network (GIHSN).

BMC Public Health. 2019 May 2;19(1):487. doi: 10.1186/s12889-019-6713-5.


The role of immune correlates of protection on the pathway to licensure, policy decision and use of group B Streptococcus vaccines for maternal immunization: considerations from World Health Organization consultations.

Vekemans J, Crofts J, Baker CJ, Goldblatt D, Heath PT, Madhi SA, Le Doare K, Andrews N, Pollard AJ, Saha SK, Schrag SJ, Smith PG, Kaslow DC.

Vaccine. 2019 May 27;37(24):3190-3198. doi: 10.1016/j.vaccine.2019.04.039. Epub 2019 Apr 25. Review.


International genomic definition of pneumococcal lineages, to contextualise disease, antibiotic resistance and vaccine impact.

Gladstone RA, Lo SW, Lees JA, Croucher NJ, van Tonder AJ, Corander J, Page AJ, Marttinen P, Bentley LJ, Ochoa TJ, Ho PL, du Plessis M, Cornick JE, Kwambana-Adams B, Benisty R, Nzenze SA, Madhi SA, Hawkins PA, Everett DB, Antonio M, Dagan R, Klugman KP, von Gottberg A, McGee L, Breiman RF, Bentley SD; Global Pneumococcal Sequencing Consortium.

EBioMedicine. 2019 May;43:338-346. doi: 10.1016/j.ebiom.2019.04.021. Epub 2019 Apr 16.


Effect of HIV-exposure and timing of anti-retroviral treatment on immunogenicity of trivalent live-attenuated polio vaccine in infants.

Moonsamy S, Suchard M, Madhi SA.

PLoS One. 2019 Apr 19;14(4):e0215079. doi: 10.1371/journal.pone.0215079. eCollection 2019.


The duopoly of ten-valent and 13-valent pneumococcal conjugate vaccines: do they differ?

Madhi SA, Goldblatt D.

Lancet Infect Dis. 2019 May;19(5):453-454. doi: 10.1016/S1473-3099(18)30785-0. Epub 2019 Apr 8. No abstract available.


HIV-Exposed Uninfected Infants Have Increased Regulatory T Cells That Correlate With Decreased T Cell Function.

Jalbert E, Williamson KM, Kroehl ME, Johnson MJ, Cutland C, Madhi SA, Nunes MC, Weinberg A.

Front Immunol. 2019 Mar 26;10:595. doi: 10.3389/fimmu.2019.00595. eCollection 2019.


Surveillance for incidence and etiology of early-onset neonatal sepsis in Soweto, South Africa.

Velaphi SC, Westercamp M, Moleleki M, Pondo T, Dangor Z, Wolter N, von Gottberg A, Shang N, Demirjian A, Winchell JM, Diaz MH, Nakwa F, Okudo G, Wadula J, Cutland C, Schrag SJ, Madhi SA.

PLoS One. 2019 Apr 10;14(4):e0214077. doi: 10.1371/journal.pone.0214077. eCollection 2019.


The Impact of Human Immunodeficiency Virus Exposure on Respiratory Syncytial Virus-associated Severe Respiratory Illness in South African Infants, 2011-2016.

McMorrow ML, Tempia S, Walaza S, Treurnicht FK, Moyes J, Cohen AL, Pretorius M, Hellferscee O, Wolter N, von Gottberg A, Nguweneza A, McAnerney JM, Naby F, Mekgoe O, Venter M, Madhi SA, Cohen C.

Clin Infect Dis. 2019 Nov 27;69(12):2208-2211. doi: 10.1093/cid/ciz288.


HLA*LA-HLA typing from linearly projected graph alignments.

Dilthey AT, Mentzer AJ, Carapito R, Cutland C, Cereb N, Madhi SA, Rhie A, Koren S, Bahram S, McVean G, Phillippy AM.

Bioinformatics. 2019 Nov 1;35(21):4394-4396. doi: 10.1093/bioinformatics/btz235.

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