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Items: 22


T Cell Receptor-induced Nuclear Factor κB (NF-κB) Signaling and Transcriptional Activation Are Regulated by STIM1- and Orai1-mediated Calcium Entry.

Liu X, Berry CT, Ruthel G, Madara JJ, MacGillivray K, Gray CM, Madge LA, McCorkell KA, Beiting DP, Hershberg U, May MJ, Freedman BD.

J Biol Chem. 2016 Apr 15;291(16):8440-52. doi: 10.1074/jbc.M115.713008. Epub 2016 Jan 29.


The NFκB paradox: RelB induces and inhibits gene expression.

Madge LA, May MJ.

Cell Cycle. 2011 Jan 1;10(1):6-7. Epub 2011 Jan 1. Review. No abstract available.


Classical NF-kappaB activation negatively regulates noncanonical NF-kappaB-dependent CXCL12 expression.

Madge LA, May MJ.

J Biol Chem. 2010 Dec 3;285(49):38069-77. doi: 10.1074/jbc.M110.147207. Epub 2010 Oct 5.


Cutting edge: association with I kappa B kinase beta regulates the subcellular localization of Homer3.

Yatherajam G, Banerjee PP, McCorkell KA, Solt LA, Hanson EP, Madge LA, Kang S, Worley PF, Orange JS, May MJ.

J Immunol. 2010 Sep 1;185(5):2665-9. doi: 10.4049/jimmunol.0903488. Epub 2010 Aug 6.


NEMO-binding domains of both IKKalpha and IKKbeta regulate IkappaB kinase complex assembly and classical NF-kappaB activation.

Solt LA, Madge LA, May MJ.

J Biol Chem. 2009 Oct 2;284(40):27596-608. doi: 10.1074/jbc.M109.047563. Epub 2009 Aug 7.


Inhibiting proinflammatory NF-kappaB signaling using cell-penetrating NEMO binding domain peptides.

Madge LA, May MJ.

Methods Mol Biol. 2009;512:209-32. doi: 10.1007/978-1-60327-530-9_11.


Hypomorphic nuclear factor-kappaB essential modulator mutation database and reconstitution system identifies phenotypic and immunologic diversity.

Hanson EP, Monaco-Shawver L, Solt LA, Madge LA, Banerjee PP, May MJ, Orange JS.

J Allergy Clin Immunol. 2008 Dec;122(6):1169-1177.e16. doi: 10.1016/j.jaci.2008.08.018. Epub 2008 Oct 11.


NKp30 ligation induces rapid activation of the canonical NF-kappaB pathway in NK cells.

Pandey R, DeStephan CM, Madge LA, May MJ, Orange JS.

J Immunol. 2007 Dec 1;179(11):7385-96.


Interleukin-1-induced NF-kappaB activation is NEMO-dependent but does not require IKKbeta.

Solt LA, Madge LA, Orange JS, May MJ.

J Biol Chem. 2007 Mar 23;282(12):8724-33. Epub 2007 Jan 23.


Effects of antisense oligonucleotide-mediated depletion of tumor necrosis factor (TNF) receptor 1-associated death domain protein on TNF-induced gene expression.

Siwkowski AM, Madge LA, Koo S, McMillan EL, Monia BP, Pober JS, Baker BF.

Mol Pharmacol. 2004 Sep;66(3):572-9.


A novel ubiquitin-like domain in IkappaB kinase beta is required for functional activity of the kinase.

May MJ, Larsen SE, Shim JH, Madge LA, Ghosh S.

J Biol Chem. 2004 Oct 29;279(44):45528-39. Epub 2004 Aug 19.


Inhibition of phosphatidylinositol 3-kinase sensitizes vascular endothelial cells to cytokine-initiated cathepsin-dependent apoptosis.

Madge LA, Li JH, Choi J, Pober JS.

J Biol Chem. 2003 Jun 6;278(23):21295-306. Epub 2003 Mar 27.


TNF signaling in vascular endothelial cells.

Madge LA, Pober JS.

Exp Mol Pathol. 2001 Jun;70(3):317-25. Review.


Caveolin-1 associates with TRAF2 to form a complex that is recruited to tumor necrosis factor receptors.

Feng X, Gaeta ML, Madge LA, Yang JH, Bradley JR, Pober JS.

J Biol Chem. 2001 Mar 16;276(11):8341-9. Epub 2000 Dec 8.


Selective inhibition of NF-kappaB activation by a peptide that blocks the interaction of NEMO with the IkappaB kinase complex.

May MJ, D'Acquisto F, Madge LA, Glöckner J, Pober JS, Ghosh S.

Science. 2000 Sep 1;289(5484):1550-4.


Biological action of leptin as an angiogenic factor.

Sierra-Honigmann MR, Nath AK, Murakami C, García-Cardeña G, Papapetropoulos A, Sessa WC, Madge LA, Schechner JS, Schwabb MB, Polverini PJ, Flores-Riveros JR.

Science. 1998 Sep 11;281(5383):1683-6.

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