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Items: 14


The Drug Repurposing Hub: a next-generation drug library and information resource.

Corsello SM, Bittker JA, Liu Z, Gould J, McCarren P, Hirschman JE, Johnston SE, Vrcic A, Wong B, Khan M, Asiedu J, Narayan R, Mader CC, Subramanian A, Golub TR.

Nat Med. 2017 Apr 7;23(4):405-408. doi: 10.1038/nm.4306. No abstract available.


Phosphorylated cortactin recruits Vav2 guanine nucleotide exchange factor to activate Rac3 and promote invadopodial function in invasive breast cancer cells.

Rosenberg BJ, Gil-Henn H, Mader CC, Halo T, Yin T, Condeelis J, Machida K, Wu YI, Koleske AJ.

Mol Biol Cell. 2017 May 15;28(10):1347-1360. doi: 10.1091/mbc.E16-12-0885. Epub 2017 Mar 29.


Immunomodulatory spherical nucleic acids.

Radovic-Moreno AF, Chernyak N, Mader CC, Nallagatla S, Kang RS, Hao L, Walker DA, Halo TL, Merkel TJ, Rische CH, Anantatmula S, Burkhart M, Mirkin CA, Gryaznov SM.

Proc Natl Acad Sci U S A. 2015 Mar 31;112(13):3892-7. doi: 10.1073/pnas.1502850112. Epub 2015 Mar 16.


Two amino acid residues confer different binding affinities of Abelson family kinase SRC homology 2 domains for phosphorylated cortactin.

Gifford SM, Liu W, Mader CC, Halo TL, Machida K, Boggon TJ, Koleske AJ.

J Biol Chem. 2014 Jul 11;289(28):19704-13. doi: 10.1074/jbc.M114.556480. Epub 2014 Jun 2.


Scanning probe-enabled nanocombinatorics define the relationship between fibronectin feature size and stem cell fate.

Giam LR, Massich MD, Hao L, Shin Wong L, Mader CC, Mirkin CA.

Proc Natl Acad Sci U S A. 2012 Mar 20;109(12):4377-82. doi: 10.1073/pnas.1201086109. Epub 2012 Mar 5.


Cortactin phosphorylation regulates cell invasion through a pH-dependent pathway.

Magalhaes MA, Larson DR, Mader CC, Bravo-Cordero JJ, Gil-Henn H, Oser M, Chen X, Koleske AJ, Condeelis J.

J Cell Biol. 2011 Nov 28;195(5):903-20. doi: 10.1083/jcb.201103045. Epub 2011 Nov 21.


Amphiastral mitotic spindle assembly in vertebrate cells lacking centrosomes.

Hornick JE, Mader CC, Tribble EK, Bagne CC, Vaughan KT, Shaw SL, Hinchcliffe EH.

Curr Biol. 2011 Apr 12;21(7):598-605. doi: 10.1016/j.cub.2011.02.049.


The vacuolar-ATPase modulates matrix metalloproteinase isoforms in human pancreatic cancer.

Chung C, Mader CC, Schmitz JC, Atladottir J, Fitchev P, Cornwell ML, Koleske AJ, Crawford SE, Gorelick F.

Lab Invest. 2011 May;91(5):732-43. doi: 10.1038/labinvest.2011.8. Epub 2011 Feb 21.


An EGFR-Src-Arg-cortactin pathway mediates functional maturation of invadopodia and breast cancer cell invasion.

Mader CC, Oser M, Magalhaes MA, Bravo-Cordero JJ, Condeelis J, Koleske AJ, Gil-Henn H.

Cancer Res. 2011 Mar 1;71(5):1730-41. doi: 10.1158/0008-5472.CAN-10-1432. Epub 2011 Jan 21.


Specific tyrosine phosphorylation sites on cortactin regulate Nck1-dependent actin polymerization in invadopodia.

Oser M, Mader CC, Gil-Henn H, Magalhaes M, Bravo-Cordero JJ, Koleske AJ, Condeelis J.

J Cell Sci. 2010 Nov 1;123(Pt 21):3662-73. doi: 10.1242/jcs.068163.


Cortactin regulates cofilin and N-WASp activities to control the stages of invadopodium assembly and maturation.

Oser M, Yamaguchi H, Mader CC, Bravo-Cordero JJ, Arias M, Chen X, Desmarais V, van Rheenen J, Koleske AJ, Condeelis J.

J Cell Biol. 2009 Aug 24;186(4):571-87. doi: 10.1083/jcb.200812176.


Arg interacts with cortactin to promote adhesion-dependent cell edge protrusion.

Lapetina S, Mader CC, Machida K, Mayer BJ, Koleske AJ.

J Cell Biol. 2009 May 4;185(3):503-19. doi: 10.1083/jcb.200809085.


The Deuterator: software for the determination of backbone amide deuterium levels from H/D exchange MS data.

Pascal BD, Chalmers MJ, Busby SA, Mader CC, Southern MR, Tsinoremas NF, Griffin PR.

BMC Bioinformatics. 2007 May 16;8:156.


An integrated in silico gene mapping strategy in inbred mice.

Cervino AC, Darvasi A, Fallahi M, Mader CC, Tsinoremas NF.

Genetics. 2007 Jan;175(1):321-33. Epub 2006 Oct 8.

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