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Items: 1 to 50 of 106

1.

The sheep genome illuminates biology of the rumen and lipid metabolism.

Jiang Y, Xie M, Chen W, Talbot R, Maddox JF, Faraut T, Wu C, Muzny DM, Li Y, Zhang W, Stanton JA, Brauning R, Barris WC, Hourlier T, Aken BL, Searle SMJ, Adelson DL, Bian C, Cam GR, Chen Y, Cheng S, DeSilva U, Dixen K, Dong Y, Fan G, Franklin IR, Fu S, Guan R, Highland MA, Holder ME, Huang G, Ingham AB, Jhangiani SN, Kalra D, Kovar CL, Lee SL, Liu W, Liu X, Lu C, Lv T, Mathew T, McWilliam S, Menzies M, Pan S, Robelin D, Servin B, Townley D, Wang W, Wei B, White SN, Yang X, Ye C, Yue Y, Zeng P, Zhou Q, Hansen JB, Kristensen K, Gibbs RA, Flicek P, Warkup CC, Jones HE, Oddy VH, Nicholas FW, McEwan JC, Kijas J, Wang J, Worley KC, Archibald AL, Cockett N, Xu X, Wang W, Dalrymple BP.

Science. 2014 Jun 6;344(6188):1168-1173. doi: 10.1126/science.1252806.

2.

SNPs for parentage testing and traceability in globally diverse breeds of sheep.

Heaton MP, Leymaster KA, Kalbfleisch TS, Kijas JW, Clarke SM, McEwan J, Maddox JF, Basnayake V, Petrik DT, Simpson B, Smith TP, Chitko-McKown CG; International Sheep Genomics Consortium.

PLoS One. 2014 Apr 16;9(4):e94851. doi: 10.1371/journal.pone.0094851. eCollection 2014.

3.

The role of hypoxia-inducible factor-1α in acetaminophen hepatotoxicity.

Sparkenbaugh EM, Saini Y, Greenwood KK, LaPres JJ, Luyendyk JP, Copple BL, Maddox JF, Ganey PE, Roth RA.

J Pharmacol Exp Ther. 2011 Aug;338(2):492-502. doi: 10.1124/jpet.111.180521. Epub 2011 May 16.

4.

Comparison of TNFα to lipopolysaccharide as an inflammagen to characterize the idiosyncratic hepatotoxicity potential of drugs: Trovafloxacin as an example.

Liguori MJ, Ditewig AC, Maddox JF, Luyendyk JP, Lehman-McKeeman LD, Nelson DM, Bhaskaran VM, Waring JF, Ganey PE, Roth RA, Blomme EA.

Int J Mol Sci. 2010 Nov 18;11(11):4697-714. doi: 10.3390/ijms11114697.

5.

Genetic linkage map of a wild genome: genomic structure, recombination and sexual dimorphism in bighorn sheep.

Poissant J, Hogg JT, Davis CS, Miller JM, Maddox JF, Coltman DW.

BMC Genomics. 2010 Sep 28;11:524. doi: 10.1186/1471-2164-11-524.

6.

The sheep genome reference sequence: a work in progress.

International Sheep Genomics Consortium, Archibald AL, Cockett NE, Dalrymple BP, Faraut T, Kijas JW, Maddox JF, McEwan JC, Hutton Oddy V, Raadsma HW, Wade C, Wang J, Wang W, Xun X.

Anim Genet. 2010 Oct;41(5):449-53. doi: 10.1111/j.1365-2052.2010.02100.x. Review.

PMID:
20809919
7.

Acute exposure to ozone exacerbates acetaminophen-induced liver injury in mice.

Aibo DI, Birmingham NP, Lewandowski R, Maddox JF, Roth RA, Ganey PE, Wagner JG, Harkema JR.

Toxicol Sci. 2010 May;115(1):267-85. doi: 10.1093/toxsci/kfq034. Epub 2010 Feb 1.

8.

Molecular cytogenetics and gene mapping in sheep (Ovis aries, 2n = 54).

Goldammer T, Di Meo GP, Lühken G, Drögemüller C, Wu CH, Kijas J, Dalrymple BP, Nicholas FW, Maddox JF, Iannuzzi L, Cockett NE.

Cytogenet Genome Res. 2009;126(1-2):63-76. doi: 10.1159/000245907. Epub 2009 Dec 9.

PMID:
20016157
9.

Bacterial- and viral-induced inflammation increases sensitivity to acetaminophen hepatotoxicity.

Maddox JF, Amuzie CJ, Li M, Newport SW, Sparkenbaugh E, Cuff CF, Pestka JJ, Cantor GH, Roth RA, Ganey PE.

J Toxicol Environ Health A. 2010;73(1):58-73. doi: 10.1080/15287390903249057.

PMID:
19953420
10.

GammadeltaTCR+ cells of the pregnant ovine uterus express variable T cell receptors and contain granulysin.

Fox A, Maddox JF, de Veer MJ, Meeusen EN.

J Reprod Immunol. 2010 Jan;84(1):52-6. doi: 10.1016/j.jri.2009.10.003. Epub 2009 Nov 30.

PMID:
19948360
11.

Cytogenetic anchoring of radiation hybrid and virtual maps of sheep chromosome X and comparison of X chromosomes in sheep, cattle, and human.

Goldammer T, Brunner RM, Rebl A, Wu CH, Nomura K, Hadfield T, Maddox JF, Cockett NE.

Chromosome Res. 2009;17(4):497-506. doi: 10.1007/s10577-009-9047-9. Epub 2009 Jul 3.

PMID:
19575301
12.

A radiation hybrid comparative map of ovine chromosome 1 aligned to the virtual sheep genome.

Wu CH, Jin W, Nomura K, Goldammer T, Hadfield T, Dalrymple BP, McWilliam S, Maddox JF, Cockett NE.

Anim Genet. 2009 Aug;40(4):435-55. doi: 10.1111/j.1365-2052.2009.01857.x. Epub 2009 Apr 7.

PMID:
19397521
13.

Genetic mapping of quantitative trait loci for resistance to Haemonchus contortus in sheep.

Marshall K, Maddox JF, Lee SH, Zhang Y, Kahn L, Graser HU, Gondro C, Walkden-Brown SW, van der Werf JH.

Anim Genet. 2009 Jun;40(3):262-72. doi: 10.1111/j.1365-2052.2008.01836.x. Epub 2009 Mar 5.

PMID:
19291139
14.

A genome wide survey of SNP variation reveals the genetic structure of sheep breeds.

Kijas JW, Townley D, Dalrymple BP, Heaton MP, Maddox JF, McGrath A, Wilson P, Ingersoll RG, McCulloch R, McWilliam S, Tang D, McEwan J, Cockett N, Oddy VH, Nicholas FW, Raadsma H; International Sheep Genomics Consortium.

PLoS One. 2009;4(3):e4668. doi: 10.1371/journal.pone.0004668. Epub 2009 Mar 3.

15.

A high-resolution comparative radiation hybrid map of ovine chromosomal regions that are homologous to human chromosome 6 (HSA6).

Wu CH, Nomura K, Goldammer T, Hadfield T, Dalrymple BP, McWilliam S, Maddox JF, Womack JE, Cockett NE.

Anim Genet. 2008 Oct;39(5):459-67. doi: 10.1111/j.1365-2052.2008.01751.x. Epub 2008 Jun 28.

PMID:
18565162
16.

Using comparative genomics to reorder the human genome sequence into a virtual sheep genome.

Dalrymple BP, Kirkness EF, Nefedov M, McWilliam S, Ratnakumar A, Barris W, Zhao S, Shetty J, Maddox JF, O'Grady M, Nicholas F, Crawford AM, Smith T, de Jong PJ, McEwan J, Oddy VH, Cockett NE; International Sheep Genomics Consortium.

Genome Biol. 2007;8(7):R152.

17.

Role of the coagulation system in acetaminophen-induced hepatotoxicity in mice.

Ganey PE, Luyendyk JP, Newport SW, Eagle TM, Maddox JF, Mackman N, Roth RA.

Hepatology. 2007 Oct;46(4):1177-86.

PMID:
17654741
18.

A radiation hybrid map of sheep chromosome 23 based on ovine BAC-end sequences.

Tetens J, Goldammer T, Maddox JF, Cockett NE, Leeb T, Drögemüller C.

Anim Genet. 2007 Apr;38(2):132-40. Epub 2007 Feb 27.

PMID:
17326803
19.

Modest inflammation enhances diclofenac hepatotoxicity in rats: role of neutrophils and bacterial translocation.

Deng X, Stachlewitz RF, Liguori MJ, Blomme EA, Waring JF, Luyendyk JP, Maddox JF, Ganey PE, Roth RA.

J Pharmacol Exp Ther. 2006 Dec;319(3):1191-9. Epub 2006 Sep 21.

PMID:
16990511
20.

Globally dispersed Y chromosomal haplotypes in wild and domestic sheep.

Meadows JR, Hanotte O, Drögemüller C, Calvo J, Godfrey R, Coltman D, Maddox JF, Marzanov N, Kantanen J, Kijas JW.

Anim Genet. 2006 Oct;37(5):444-53.

PMID:
16978172
21.

Modeling inflammation-drug interactions in vitro: a rat Kupffer cell-hepatocyte coculture system.

Tukov FF, Maddox JF, Amacher DE, Bobrowski WF, Roth RA, Ganey PE.

Toxicol In Vitro. 2006 Dec;20(8):1488-99. Epub 2006 May 11.

PMID:
16782301
22.

Unique gene expression and hepatocellular injury in the lipopolysaccharide-ranitidine drug idiosyncrasy rat model: comparison with famotidine.

Luyendyk JP, Lehman-McKeeman LD, Nelson DM, Bhaskaran VM, Reilly TP, Car BD, Cantor GH, Maddox JF, Ganey PE, Roth RA.

Toxicol Sci. 2006 Apr;90(2):569-85. Epub 2006 Jan 16.

PMID:
16415329
23.

Coagulation-dependent gene expression and liver injury in rats given lipopolysaccharide with ranitidine but not with famotidine.

Luyendyk JP, Lehman-McKeeman LD, Nelson DM, Bhaskaran VM, Reilly TP, Car BD, Cantor GH, Deng X, Maddox JF, Ganey PE, Roth RA.

J Pharmacol Exp Ther. 2006 May;317(2):635-43. Epub 2006 Jan 9.

PMID:
16401727
24.

Microarray analysis of lipopolysaccharide potentiation of trovafloxacin-induced liver injury in rats suggests a role for proinflammatory chemokines and neutrophils.

Waring JF, Liguori MJ, Luyendyk JP, Maddox JF, Ganey PE, Stachlewitz RF, North C, Blomme EA, Roth RA.

J Pharmacol Exp Ther. 2006 Mar;316(3):1080-7. Epub 2005 Nov 18.

PMID:
16299187
25.

Metabonomic evaluation of idiosyncrasy-like liver injury in rats cotreated with ranitidine and lipopolysaccharide.

Maddox JF, Luyendyk JP, Cosma GN, Breau AP, Bible RH Jr, Harrigan GG, Goodacre R, Ganey PE, Cantor GH, Cockerell GL, Roth RA.

Toxicol Appl Pharmacol. 2006 Apr 1;212(1):35-44. Epub 2005 Jul 27.

PMID:
16051291
26.

Coagulation-mediated hypoxia and neutrophil-dependent hepatic injury in rats given lipopolysaccharide and ranitidine.

Luyendyk JP, Shaw PJ, Green CD, Maddox JF, Ganey PE, Roth RA.

J Pharmacol Exp Ther. 2005 Sep;314(3):1023-31. Epub 2005 Jun 2.

PMID:
15933155
27.
28.

Role of hepatic fibrin in idiosyncrasy-like liver injury from lipopolysaccharide-ranitidine coexposure in rats.

Luyendyk JP, Maddox JF, Green CD, Ganey PE, Roth RA.

Hepatology. 2004 Dec;40(6):1342-51.

PMID:
15565632
29.

Adverse hepatic drug reactions: inflammatory episodes as consequence and contributor.

Ganey PE, Luyendyk JP, Maddox JF, Roth RA.

Chem Biol Interact. 2004 Nov 1;150(1):35-51. Review.

PMID:
15522260
30.

Gene expression analysis points to hemostasis in livers of rats cotreated with lipopolysaccharide and ranitidine.

Luyendyk JP, Mattes WB, Burgoon LD, Zacharewski TR, Maddox JF, Cosma GN, Ganey PE, Roth RA.

Toxicol Sci. 2004 Jul;80(1):203-13. Epub 2004 Apr 14.

PMID:
15084757
31.

Systematic screening of sheep skin cDNA libraries for microsatellite sequences.

DeSilva U, Franklin IR, Maddox JF, van Hest B, Adelson DL.

Cytogenet Genome Res. 2003;102(1-4):79-84.

PMID:
14970683
32.

Application of high-throughput Fourier-transform infrared spectroscopy in toxicology studies: contribution to a study on the development of an animal model for idiosyncratic toxicity.

Harrigan GG, LaPlante RH, Cosma GN, Cockerell G, Goodacre R, Maddox JF, Luyendyk JP, Ganey PE, Roth RA.

Toxicol Lett. 2004 Feb 2;146(3):197-205.

PMID:
14687757
33.

15-deoxy prostaglandin J2 enhances allyl alcohol-induced toxicity in rat hepatocytes.

Maddox JF, Domzalski AC, Roth RA, Ganey PE.

Toxicol Sci. 2004 Feb;77(2):290-8. Epub 2003 Dec 2.

PMID:
14657518
34.

Modes of cell death in rat liver after monocrotaline exposure.

Copple BL, Rondelli CM, Maddox JF, Hoglen NC, Ganey PE, Roth RA.

Toxicol Sci. 2004 Jan;77(1):172-82. Epub 2003 Nov 4.

PMID:
14600277
35.

Inflammation and drug idiosyncrasy--is there a connection?

Roth RA, Luyendyk JP, Maddox JF, Ganey PE.

J Pharmacol Exp Ther. 2003 Oct;307(1):1-8. Epub 2003 Sep 3.

PMID:
12954806
36.

Ranitidine treatment during a modest inflammatory response precipitates idiosyncrasy-like liver injury in rats.

Luyendyk JP, Maddox JF, Cosma GN, Ganey PE, Cockerell GL, Roth RA.

J Pharmacol Exp Ther. 2003 Oct;307(1):9-16. Epub 2003 Jul 31.

PMID:
12893837
37.

Allyl alcohol activation of protein kinase C delta leads to cytotoxicity of rat hepatocytes.

Maddox JF, Roth RA, Ganey PE.

Chem Res Toxicol. 2003 May;16(5):609-15.

PMID:
12755590
38.

Ovine T-cell receptor gamma genes contain polymorphic microsatellites.

Diez-Tascón C, Maddox JF, Dodds KG, Crawford AM.

Anim Genet. 2002 Dec;33(6):468-70. No abstract available.

PMID:
12464026
39.

A genome scan for quantitative trait loci affecting resistance to Trichostrongylus colubriformis in sheep.

Beh KJ, Hulme DJ, Callaghan MJ, Leish Z, Lenane I, Windon RG, Maddox JF.

Anim Genet. 2002 Apr;33(2):97-106.

PMID:
12047222
41.
42.

The Sheep Gene Map.

Broad TE, Hill DF, Maddox JF, Montgomery GW, Nicholas FW.

ILAR J. 1998;39(2-3):160-170. No abstract available.

PMID:
11528074
43.

An enhanced linkage map of the sheep genome comprising more than 1000 loci.

Maddox JF, Davies KP, Crawford AM, Hulme DJ, Vaiman D, Cribiu EP, Freking BA, Beh KJ, Cockett NE, Kang N, Riffkin CD, Drinkwater R, Moore SS, Dodds KG, Lumsden JM, van Stijn TC, Phua SH, Adelson DL, Burkin HR, Broom JE, Buitkamp J, Cambridge L, Cushwa WT, Gerard E, Galloway SM, Harrison B, Hawken RJ, Hiendleder S, Henry HM, Medrano JF, Paterson KA, Schibler L, Stone RT, van Hest B.

Genome Res. 2001 Jul;11(7):1275-89.

44.

Increased 15-HPETE production decreases prostacyclin synthase activity during oxidant stress in aortic endothelial cells.

Weaver JA, Maddox JF, Cao YZ, Mullarky IK, Sordillo LM.

Free Radic Biol Med. 2001 Feb 1;30(3):299-308.

PMID:
11165876
45.

Linkage and physical mapping of the sheep perforin (PRF1) gene to OAR 25.

Maddox JF, Andrews AE, Gill CA, Bottema CD.

Anim Genet. 2000 Jun;31(3):231-2. No abstract available.

PMID:
10895320
46.

Dinucleotide repeat polymorphism at the ovine McMA7, McMA10, McMA13, McMA16, McMA17, McMA27, McMA29, McMA42, McMA47 and McMA49 loci.

Beh KJ, Riffkin CD, Davies KP, di Ienno KL, Maddox JF.

Anim Genet. 2000 Jun;31(3):228-9. No abstract available.

PMID:
10895317
47.

Dinucleotide repeat polymorphism at the ovine McMA1, McMA2, McMA5, McMA8, McMA9, McMA11, McMA14, McMA20, McMA24, McMA26 loci.

Maddox JF, Riffkin CD, Beh KJ.

Anim Genet. 2000 Apr;31(2):148-9. No abstract available.

PMID:
10782226
48.

Linkage mapping of goat ChirUCO, LSCV and SR-CRSP microsatellites in sheep.

Maddox JF, Schibler L, Cribiu EP, Kang N, Davies KP, Vaiman D.

Anim Genet. 2000 Apr;31(2):145. No abstract available. Erratum in: Anim Genet 2000 Aug;31(4):292-3.

PMID:
10782222
49.

Chromosomal assignments and polymorphism information content in sheep for 12 cattle microsatellites.

Maddox JF.

Anim Genet. 2000 Apr;31(2):144-5. No abstract available.

PMID:
10782221
50.

Single strand conformational polymorphisms in the second exons of the ovine DMB, DYA and DYB genes.

Maddox JF.

Anim Genet. 1999 Oct;30(5):382-3. No abstract available.

PMID:
10582285

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