Sort by
Items per page

Send to

Choose Destination

Search results

Items: 19


Zebrafish as a Model for Obesity and Diabetes.

Zang L, Maddison LA, Chen W.

Front Cell Dev Biol. 2018 Aug 20;6:91. doi: 10.3389/fcell.2018.00091. eCollection 2018. Review.


Modeling Pancreatic Endocrine Cell Adaptation and Diabetes in the Zebrafish.

Maddison LA, Chen W.

Front Endocrinol (Lausanne). 2017 Jan 26;8:9. doi: 10.3389/fendo.2017.00009. eCollection 2017. Review.


Multiplex conditional mutagenesis in zebrafish using the CRISPR/Cas system.

Yin L, Maddison LA, Chen W.

Methods Cell Biol. 2016;135:3-17. doi: 10.1016/bs.mcb.2016.04.018. Epub 2016 May 30.


Multiplex Conditional Mutagenesis Using Transgenic Expression of Cas9 and sgRNAs.

Yin L, Maddison LA, Li M, Kara N, LaFave MC, Varshney GK, Burgess SM, Patton JG, Chen W.

Genetics. 2015 Jun;200(2):431-41. doi: 10.1534/genetics.115.176917. Epub 2015 Apr 8.


Skeletal muscle insulin resistance in zebrafish induces alterations in β-cell number and glucose tolerance in an age- and diet-dependent manner.

Maddison LA, Joest KE, Kammeyer RM, Chen W.

Am J Physiol Endocrinol Metab. 2015 Apr 15;308(8):E662-9. doi: 10.1152/ajpendo.00441.2014. Epub 2015 Feb 10.


Overnutrition induces β-cell differentiation through prolonged activation of β-cells in zebrafish larvae.

Li M, Maddison LA, Page-McCaw P, Chen W.

Am J Physiol Endocrinol Metab. 2014 Apr 1;306(7):E799-807. doi: 10.1152/ajpendo.00686.2013. Epub 2014 Jan 28.


Conditional gene-trap mutagenesis in zebrafish.

Maddison LA, Li M, Chen W.

Methods Mol Biol. 2014;1101:393-411. doi: 10.1007/978-1-62703-721-1_19.


Targeted overexpression of CKI-insensitive cyclin-dependent kinase 4 increases functional β-cell number through enhanced self-replication in zebrafish.

Li M, Maddison LA, Crees Z, Chen W.

Zebrafish. 2013 Jun;10(2):170-6. doi: 10.1089/zeb.2012.0816. Epub 2013 Apr 1.


Conditional control of gene function by an invertible gene trap in zebrafish.

Ni TT, Lu J, Zhu M, Maddison LA, Boyd KL, Huskey L, Ju B, Hesselson D, Zhong TP, Page-McCaw PS, Stainier DY, Chen W.

Proc Natl Acad Sci U S A. 2012 Sep 18;109(38):15389-94. Epub 2012 Aug 20.


Nutrient excess stimulates β-cell neogenesis in zebrafish.

Maddison LA, Chen W.

Diabetes. 2012 Oct;61(10):2517-24. Epub 2012 Jun 20.


Generating conditional mutations in zebrafish using gene-trap mutagenesis.

Maddison LA, Lu J, Chen W.

Methods Cell Biol. 2011;104:1-22. doi: 10.1016/B978-0-12-374814-0.00001-X.


PhiC31 integrase induces efficient site-specific excision in zebrafish.

Lu J, Maddison LA, Chen W.

Transgenic Res. 2011 Feb;20(1):183-9. doi: 10.1007/s11248-010-9394-5. Epub 2010 Jun 17.


A gain-of-function screen in zebrafish identifies a guanylate cyclase with a role in neuronal degeneration.

Maddison LA, Lu J, Victoroff T, Scott E, Baier H, Chen W.

Mol Genet Genomics. 2009 May;281(5):551-63. doi: 10.1007/s00438-009-0428-8. Epub 2009 Feb 17.


Conditional deletion of Rb causes early stage prostate cancer.

Maddison LA, Sutherland BW, Barrios RJ, Greenberg NM.

Cancer Res. 2004 Sep 1;64(17):6018-25.


Prostate-specific expression of p53(R172L) differentially regulates p21, Bax, and mdm2 to inhibit prostate cancer progression and prolong survival.

Hernandez I, Maddison LA, Wei Y, DeMayo F, Petras T, Li B, Gingrich JR, Rosen JM, Greenberg NM.

Mol Cancer Res. 2003 Dec;1(14):1036-47.


Pathobiology of autochthonous prostate cancer in a pre-clinical transgenic mouse model.

Kaplan-Lefko PJ, Chen TM, Ittmann MM, Barrios RJ, Ayala GE, Huss WJ, Maddison LA, Foster BA, Greenberg NM.

Prostate. 2003 May 15;55(3):219-37.


Autochthonous mouse models for prostate cancer: past, present and future.

Huss WJ, Maddison LA, Greenberg NM.

Semin Cancer Biol. 2001 Jun;11(3):245-60. Review.


Prostate specific expression of Cre recombinase in transgenic mice.

Maddison LA, Nahm H, DeMayo F, Greenberg NM.

Genesis. 2000 Feb;26(2):154-6. No abstract available.


Supplemental Content

Loading ...
Support Center