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Items: 5


Aberrant Epidermal Growth Factor Receptor RNA Splice Products Are Among the Most Frequent Somatic Alterations in Clear Cell Renal Cell Carcinoma and Are Associated with a Poor Response to Immunotherapy.

Zaman S, Hajiran A, Coba GA, Robinson T, Madanayake TW, Segarra DT, Chobrutskiy BI, Boyle TA, Zhou JM, Kim Y, Mulé JJ, Teer JK, Manley BJ.

Eur Urol Focus. 2019 Dec 31. pii: S2405-4569(19)30379-7. doi: 10.1016/j.euf.2019.12.001. [Epub ahead of print]


Aptamer-guided upconversion nanoplatform for targeted drug delivery and near-infrared light-triggered photodynamic therapy.

Lin HC, Li WT, Madanayake TW, Tao C, Niu Q, Yan SQ, Gao BA, Ping Z.

J Biomater Appl. 2020 Jan;34(6):875-888. doi: 10.1177/0885328219882152. Epub 2019 Oct 17. No abstract available.


HMGB1 binds to the KRAS promoter G-quadruplex: a new player in oncogene transcriptional regulation?

Amato J, Madanayake TW, Iaccarino N, Novellino E, Randazzo A, Hurley LH, Pagano B.

Chem Commun (Camb). 2018 Aug 21;54(68):9442-9445. doi: 10.1039/c8cc03614d.


A transcriptomic approach to elucidate the physiological significance of human cytochrome P450 2S1 in bronchial epithelial cells.

Madanayake TW, Lindquist IE, Devitt NP, Mudge J, Rowland AM.

BMC Genomics. 2013 Nov 26;14:833. doi: 10.1186/1471-2164-14-833.


Cytochrome P450 2S1 depletion enhances cell proliferation and migration in bronchial epithelial cells, in part, through modulation of prostaglandin E(2) synthesis.

Madanayake TW, Fidler TP, Fresquez TM, Bajaj N, Rowland AM.

Drug Metab Dispos. 2012 Nov;40(11):2119-25. doi: 10.1124/dmd.112.046466. Epub 2012 Aug 3.

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