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Items: 1 to 50 of 141

1.

The TNF-derived TIP peptide activates the epithelial sodium channel and ameliorates experimental nephrotoxic serum nephritis.

Madaio MP, Czikora I, Kvirkvelia N, McMenamin M, Yue Q, Liu T, Toque HA, Sridhar S, Covington K, Alaisami R, O'Connor PM, Caldwell RW, Chen JK, Clauss M, Brands MW, Eaton DC, Romero MJ, Lucas R.

Kidney Int. 2019 Jun;95(6):1359-1372. doi: 10.1016/j.kint.2018.12.022. Epub 2019 Mar 21.

PMID:
30905471
2.

Kidney-targeted inhibition of protein kinase C-α ameliorates nephrotoxic nephritis with restoration of mitochondrial dysfunction.

Kvirkvelia N, McMenamin M, Warren M, Jadeja RN, Kodeboyina SK, Sharma A, Zhi W, O'Connor PM, Raju R, Lucas R, Madaio MP.

Kidney Int. 2018 Aug;94(2):280-291. doi: 10.1016/j.kint.2018.01.032. Epub 2018 May 4.

3.

Attenuated Macrophage Infiltration in Glomeruli of Aged Mice Resulting in Ameliorated Kidney Injury in Nephrotoxic Serum Nephritis.

Kaneko Y, Cho T, Sato Y, Goto K, Yamamoto S, Goto S, Madaio MP, Narita I.

J Gerontol A Biol Sci Med Sci. 2018 Aug 10;73(9):1178-1186. doi: 10.1093/gerona/gly019.

PMID:
29415117
4.

Best Practices for Physician-Scientist Training Programs: Recommendations from the Alliance for Academic Internal Medicine.

Blanchard M, Burton MC, Geraci MW, Madaio MP, Marsh JD, Proweller A, Rockey DC, Salata RA, Tan W, Williams CS, Zaidi M, Todd RF 3rd.

Am J Med. 2018 May;131(5):578-584. doi: 10.1016/j.amjmed.2018.01.015. Epub 2018 Feb 2. No abstract available.

PMID:
29410155
5.

U.S. Physician-Scientist Workforce in the 21st Century: Recommendations to Attract and Sustain the Pipeline.

Salata RA, Geraci MW, Rockey DC, Blanchard M, Brown NJ, Cardinal LJ, Garcia M, Madaio MP, Marsh JD, Todd RF 3rd.

Acad Med. 2018 Apr;93(4):565-573. doi: 10.1097/ACM.0000000000001950.

6.

Leptin deficiency down-regulates IL-23 production in glomerular podocytes resulting in an attenuated immune response in nephrotoxic serum nephritis.

Goto K, Kaneko Y, Sato Y, Otsuka T, Yamamoto S, Goto S, Yamamoto K, Yamamoto T, Kawachi H, Madaio MP, Narita I.

Int Immunol. 2016 Apr;28(4):197-208. doi: 10.1093/intimm/dxv067. Epub 2015 Nov 13.

7.

Human anti-α3(IV)NC1 antibody drug conjugates target glomeruli to resolve nephritis.

Kvirkvelia N, McMenamin M, Gutierrez VI, Lasareishvili B, Madaio MP.

Am J Physiol Renal Physiol. 2015 Oct 15;309(8):F680-4. doi: 10.1152/ajprenal.00289.2015. Epub 2015 Aug 19.

8.

The amino acid sensor GCN2 inhibits inflammatory responses to apoptotic cells promoting tolerance and suppressing systemic autoimmunity.

Ravishankar B, Liu H, Shinde R, Chaudhary K, Xiao W, Bradley J, Koritzinsky M, Madaio MP, McGaha TL.

Proc Natl Acad Sci U S A. 2015 Aug 25;112(34):10774-9. doi: 10.1073/pnas.1504276112. Epub 2015 Aug 10.

9.

Amino acid metabolism inhibits antibody-driven kidney injury by inducing autophagy.

Chaudhary K, Shinde R, Liu H, Gnana-Prakasam JP, Veeranan-Karmegam R, Huang L, Ravishankar B, Bradley J, Kvirkvelia N, McMenamin M, Xiao W, Kleven D, Mellor AL, Madaio MP, McGaha TL.

J Immunol. 2015 Jun 15;194(12):5713-24. doi: 10.4049/jimmunol.1500277. Epub 2015 May 15.

10.

Lupus Nephritis: Animal Modeling of a Complex Disease Syndrome Pathology.

McGaha TL, Madaio MP.

Drug Discov Today Dis Models. 2014 Spring;11:13-18.

11.

T cell-independent B cell activation induces immunosuppressive sialylated IgG antibodies.

Hess C, Winkler A, Lorenz AK, Holecska V, Blanchard V, Eiglmeier S, Schoen AL, Bitterling J, Stoehr AD, Petzold D, Schommartz T, Mertes MM, Schoen CT, Tiburzy B, Herrmann A, Köhl J, Manz RA, Madaio MP, Berger M, Wardemann H, Ehlers M.

J Clin Invest. 2013 Sep;123(9):3788-96. doi: 10.1172/JCI65938. Epub 2013 Aug 27.

12.

HRES-1/Rab4-mediated depletion of Drp1 impairs mitochondrial homeostasis and represents a target for treatment in SLE.

Caza TN, Fernandez DR, Talaber G, Oaks Z, Haas M, Madaio MP, Lai ZW, Miklossy G, Singh RR, Chudakov DM, Malorni W, Middleton F, Banki K, Perl A.

Ann Rheum Dis. 2014 Oct;73(10):1888-97. doi: 10.1136/annrheumdis-2013-203794. Epub 2013 Jul 29.

13.

A human monoclonal antibody against the collagen type IV α3NC1 domain is a non-invasive optical biomarker for glomerular diseases.

Chaudhary K, Kleven DT, McGaha TL, Madaio MP.

Kidney Int. 2013 Aug;84(2):403-8. doi: 10.1038/ki.2013.99. Epub 2013 Mar 20.

14.

Prostaglandin E2 promotes cellular recovery from established nephrotoxic serum nephritis in mice, prosurvival, and regenerative effects on glomerular cells.

Kvirkvelia N, McMenamin M, Chaudhary K, Bartoli M, Madaio MP.

Am J Physiol Renal Physiol. 2013 Mar 1;304(5):F463-70. doi: 10.1152/ajprenal.00575.2012. Epub 2013 Jan 2.

15.

Absence of CD59 exacerbates systemic autoimmunity in MRL/lpr mice.

Miwa T, Zhou L, Maldonado MA, Madaio MP, Eisenberg RA, Song WC.

J Immunol. 2012 Dec 1;189(11):5434-41. doi: 10.4049/jimmunol.1201621. Epub 2012 Oct 29.

16.

The relevance of antigen binding to the pathogenicity of lupus autoantibodies.

Madaio MP.

Kidney Int. 2012 Jul;82(2):125-7. doi: 10.1038/ki.2012.159.

17.

Anti-tumor necrosis factor α treatment of interferon-α-induced murine lupus nephritis reduces the renal macrophage response but does not alter glomerular immune complex formation.

Bethunaickan R, Sahu R, Liu Z, Tang YT, Huang W, Edegbe O, Tao H, Ramanujam M, Madaio MP, Davidson A.

Arthritis Rheum. 2012 Oct;64(10):3399-408. doi: 10.1002/art.34553.

18.

Heterologous protein incites abnormal plasma cell accumulation and autoimmunity in MRL-MpJ mice.

McGaha TL, Ma Z, Ravishankar B, Gabunia K, McMenamin M, Madaio MP.

Autoimmunity. 2012 Jun;45(4):279-89. doi: 10.3109/08916934.2012.654864. Epub 2012 Feb 23.

PMID:
22283427
19.

IFN-α confers resistance of systemic lupus erythematosus nephritis to therapy in NZB/W F1 mice.

Liu Z, Bethunaickan R, Huang W, Ramanujam M, Madaio MP, Davidson A.

J Immunol. 2011 Aug 1;187(3):1506-13. doi: 10.4049/jimmunol.1004142. Epub 2011 Jun 24.

20.

Interferon-α accelerates murine systemic lupus erythematosus in a T cell-dependent manner.

Liu Z, Bethunaickan R, Huang W, Lodhi U, Solano I, Madaio MP, Davidson A.

Arthritis Rheum. 2011 Jan;63(1):219-29. doi: 10.1002/art.30087.

21.

Biomarkers in lupus nephritis.

Manoharan A, Madaio MP.

Rheum Dis Clin North Am. 2010 Feb;36(1):131-43, ix. doi: 10.1016/j.rdc.2009.12.009.

PMID:
20202595
22.

Selective blockade of BAFF for the prevention and treatment of systemic lupus erythematosus nephritis in NZM2410 mice.

Ramanujam M, Bethunaickan R, Huang W, Tao H, Madaio MP, Davidson A.

Arthritis Rheum. 2010 May;62(5):1457-68. doi: 10.1002/art.27368.

23.
24.

Poly(ADP-ribose) polymerase-1 regulates the progression of autoimmune nephritis in males by inducing necrotic cell death and modulating inflammation.

Jog NR, Dinnall JA, Gallucci S, Madaio MP, Caricchio R.

J Immunol. 2009 Jun 1;182(11):7297-306. doi: 10.4049/jimmunol.0803565.

25.

Interferon-alpha treatment of female (NZW x BXSB)F(1) mice mimics some but not all features associated with the Yaa mutation.

Ramanujam M, Kahn P, Huang W, Tao H, Madaio MP, Factor SM, Davidson A.

Arthritis Rheum. 2009 Apr;60(4):1096-101. doi: 10.1002/art.24414.

26.

Prevention of murine antiphospholipid syndrome by BAFF blockade.

Kahn P, Ramanujam M, Bethunaickan R, Huang W, Tao H, Madaio MP, Factor SM, Davidson A.

Arthritis Rheum. 2008 Sep;58(9):2824-34. doi: 10.1002/art.23764.

27.

Systemic lupus international collaborating clinics renal activity/response exercise: development of a renal activity score and renal response index.

Petri M, Kasitanon N, Lee SS, Link K, Magder L, Bae SC, Hanly JG, Isenberg DA, Nived O, Sturfelt G, van Vollenhoven R, Wallace DJ, Alarcón GS, Adu D, Avila-Casado C, Bernatsky SR, Bruce IN, Clarke AE, Contreras G, Fine DM, Gladman DD, Gordon C, Kalunian KC, Madaio MP, Rovin BH, Sanchez-Guerrero J, Steinsson K, Aranow C, Balow JE, Buyon JP, Ginzler EM, Khamashta MA, Urowitz MB, Dooley MA, Merrill JT, Ramsey-Goldman R, Font J, Tumlin J, Stoll T, Zoma A; Systemic Lupus International Collaborating Clinics.

Arthritis Rheum. 2008 Jun;58(6):1784-8. doi: 10.1002/art.23456. Erratum in: Arthritis Rheum. 2008 Sep;58(9):2823.

28.

Systemic lupus international collaborating clinics renal activity/response exercise: comparison of agreement in rating renal response.

Petri M, Kasitanon N, Singh S, Link K, Magder L, Bae SC, Hanly JG, Nived O, Sturfelt G, van Vollenhoven R, Wallace DJ, Alarcón GS, Adu D, Avila-Casado C, Bernatsky SR, Bruce IN, Clarke AE, Contreras G, Fine DM, Gladman DD, Gordon C, Kalunian KC, Madaio MP, Rovin BH, Sanchez-Guerrero J, Steinsson K, Aranow C, Balow JE, Buyon JP, Ginzler EM, Khamashta MA, Urowitz MB, Dooley MA, Merrill JT, Ramsey-Goldman R, Font J, Tumlin J, Stoll T, Zoma A; Systemic Lupus International Collaborating Clinics.

Arthritis Rheum. 2008 Jun;58(6):1789-95. doi: 10.1002/art.23802.

29.

Activated renal macrophages are markers of disease onset and disease remission in lupus nephritis.

Schiffer L, Bethunaickan R, Ramanujam M, Huang W, Schiffer M, Tao H, Madaio MP, Bottinger EP, Davidson A.

J Immunol. 2008 Feb 1;180(3):1938-47. Erratum in: J Immunol. 2008 Mar 1;180(5):3613. Madaio, Michael M [corrected to Madaio, Michael P].

30.

Idiopathic IgA nephropathy: pathogenesis, histopathology, and therapeutic options.

Tumlin JA, Madaio MP, Hennigar R.

Clin J Am Soc Nephrol. 2007 Sep;2(5):1054-61. Epub 2007 Aug 16. Review.

31.

Modulation of autoimmunity by TLR9 in the chronic graft-vs-host model of systemic lupus erythematosus.

Ma Z, Chen F, Madaio MP, Cohen PL, Eisenberg RA.

J Immunol. 2006 Nov 15;177(10):7444-50.

32.

DAF/Crry double deficiency in mice exacerbates nephrotoxic serum-induced proteinuria despite markedly reduced systemic complement activity.

Miwa T, Zhou L, Tudoran R, Lambris JD, Madaio MP, Nangaku M, Molina H, Song WC.

Mol Immunol. 2007 Jan;44(1-3):139-46. Epub 2006 Aug 2.

PMID:
16887189
33.

Pathology and protection in nephrotoxic nephritis is determined by selective engagement of specific Fc receptors.

Kaneko Y, Nimmerjahn F, Madaio MP, Ravetch JV.

J Exp Med. 2006 Mar 20;203(3):789-97. Epub 2006 Mar 6.

34.

Simvastatin protection against acute immune-mediated glomerulonephritis in mice.

Christensen M, Su AW, Snyder RW, Greco A, Lipschutz JH, Madaio MP.

Kidney Int. 2006 Feb;69(3):457-63.

35.

The mitochondrial and kidney disease phenotypes of kd/kd mice under germfree conditions.

Hallman TM, Peng M, Meade R, Hancock WW, Madaio MP, Gasser DL.

J Autoimmun. 2006 Feb;26(1):1-6. Epub 2005 Dec 6.

36.

Glomerular and tubular epithelial defects in kd/kd mice lead to progressive renal failure.

Madaio MP, Ahima RS, Meade R, Rader DJ, Mendoza A, Peng M, Tomaszewski JE, Hancock WW, Gasser DL.

Am J Nephrol. 2005 Nov-Dec;25(6):604-10. Epub 2005 Nov 9.

37.

The kd/kd mouse is a model of collapsing glomerulopathy.

Barisoni L, Madaio MP, Eraso M, Gasser DL, Nelson PJ.

J Am Soc Nephrol. 2005 Oct;16(10):2847-51. Epub 2005 Aug 24.

38.

Diagnosis and treatment of nephrotic syndrome.

Verma SP, Madaio MP.

Expert Opin Investig Drugs. 1999 Jun;8(6):787-96.

PMID:
15992131
39.
40.

Pathogenic autoantibodies in lupus nephritis.

Waldman M, Madaio MP.

Lupus. 2005;14(1):19-24. Review.

PMID:
15732283
41.

Mechanism of action of transmembrane activator and calcium modulator ligand interactor-Ig in murine systemic lupus erythematosus.

Ramanujam M, Wang X, Huang W, Schiffer L, Grimaldi C, Akkerman A, Diamond B, Madaio MP, Davidson A.

J Immunol. 2004 Sep 1;173(5):3524-34.

42.

Mutant prenyltransferase-like mitochondrial protein (PLMP) and mitochondrial abnormalities in kd/kd mice.

Peng M, Jarett L, Meade R, Madaio MP, Hancock WW, George AL Jr, Neilson EG, Gasser DL.

Kidney Int. 2004 Jul;66(1):20-8.

43.
44.

Recent advances in the pathogenesis of lupus nephritis: autoantibodies and B cells.

Su W, Madaio MP.

Semin Nephrol. 2003 Nov;23(6):564-8. Review.

PMID:
14631564
45.

Lifespan is prolonged in autoimmune-prone (NZB/NZW) F1 mice fed a diet supplemented with indole-3-carbinol.

Auborn KJ, Qi M, Yan XJ, Teichberg S, Chen D, Madaio MP, Chiorazzi N.

J Nutr. 2003 Nov;133(11):3610-3.

PMID:
14608082
46.

Role of the H-2 haplotype in Fas-intact lupus-prone MRL mice: association with autoantibodies but not renal disease.

Kong PL, Zhu T, Madaio MP, Craft J.

Arthritis Rheum. 2003 Oct;48(10):2992-5. No abstract available.

47.

Cutting Edge: Multiple autoimmune pathways in kd/kd mice.

Hancock WW, Tsai TL, Madaio MP, Gasser DL.

J Immunol. 2003 Sep 15;171(6):2778-81.

48.

Short term administration of costimulatory blockade and cyclophosphamide induces remission of systemic lupus erythematosus nephritis in NZB/W F1 mice by a mechanism downstream of renal immune complex deposition.

Schiffer L, Sinha J, Wang X, Huang W, von Gersdorff G, Schiffer M, Madaio MP, Davidson A.

J Immunol. 2003 Jul 1;171(1):489-97. Erratum in: J Immunol. 2003 Aug 1;171(3):1610. Von Gonsdorff Gero [corrected to von Gersdorff Gero].

49.

The role of antibodies and B cells in the pathogenesis of lupus nephritis.

Shlomchik MJ, Madaio MP.

Springer Semin Immunopathol. 2003 May;24(4):363-75. Review.

PMID:
12778333
50.

Lupus autoantibodies 101: one size does not fit all; however, specificity influences pathogenicity.

Madaio MP.

Clin Exp Immunol. 2003 Mar;131(3):396-7. No abstract available.

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