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MCL1 is Required for Maintenance of Intestinal Homeostasis and Prevention of Carcinogenesis in Mice.

Healy ME, Boege Y, Hodder MC, Böhm F, Malehmir M, Scherr AL, Jetzer J, Chan LK, Parrotta R, Jacob K, Clerbaux LA, Kreutzer S, Campbell A, Gilchrist E, Gilroy K, Rodewald AK, Honcharova-Biletska H, Schimmer R, Vélez K, Büeler S, Cammareri P, Kalna G, Wenning AS, McCoy KD, Gomez de Agüero M, Schulze-Bergkamen H, Klose C, Unger K, Macpherson AJ, Moor AE, Köhler B, Sansom OJ, Heikenwalder M, Weber A.

Gastroenterology. 2020 Mar 13. pii: S0016-5085(20)30338-3. doi: 10.1053/j.gastro.2020.03.017. [Epub ahead of print]


Association of Immigrant and Refugee Status With Risk Factors for Exposure to Violent Assault Among Youths and Young Adults in Canada.

Saunders NR, Guan J, Macpherson A, Lu H, Guttmann A.

JAMA Netw Open. 2020 Mar 2;3(3):e200375. doi: 10.1001/jamanetworkopen.2020.0375.


TACAN Is an Ion Channel Involved in Sensing Mechanical Pain.

Beaulieu-Laroche L, Christin M, Donoghue A, Agosti F, Yousefpour N, Petitjean H, Davidova A, Stanton C, Khan U, Dietz C, Faure E, Fatima T, MacPherson A, Mouchbahani-Constance S, Bisson DG, Haglund L, Ouellet JA, Stone LS, Samson J, Smith MJ, Ask K, Ribeiro-da-Silva A, Blunck R, Poole K, Bourinet E, Sharif-Naeini R.

Cell. 2020 Mar 5;180(5):956-967.e17. doi: 10.1016/j.cell.2020.01.033. Epub 2020 Feb 20.


"Who is the right patient?" Insights into decisions to transfer pediatric trauma patients.

Candy S, Schuurman N, MacPherson A, Schoon R, Rondeau K, Yanchar NL.

J Pediatr Surg. 2020 Jan 31. pii: S0022-3468(20)30087-7. doi: 10.1016/j.jpedsurg.2020.01.048. [Epub ahead of print]


Neuronal programming by microbiota regulates intestinal physiology.

Obata Y, Castaño Á, Boeing S, Bon-Frauches AC, Fung C, Fallesen T, de Agüero MG, Yilmaz B, Lopes R, Huseynova A, Horswell S, Maradana MR, Boesmans W, Vanden Berghe P, Murray AJ, Stockinger B, Macpherson AJ, Pachnis V.

Nature. 2020 Feb;578(7794):284-289. doi: 10.1038/s41586-020-1975-8. Epub 2020 Feb 5.


White Matter Integrity and Its Relationship to Cognitive-Motor Integration in Females with and without Post-Concussion Syndrome.

Hurtubise JM, Gorbet DJ, Hynes LM, Macpherson AK, Sergio LE.

J Neurotrauma. 2020 Mar 18. doi: 10.1089/neu.2019.6765. [Epub ahead of print]


Implementing a junior high school-based programme to reduce sports injuries through neuromuscular training (iSPRINT): a cluster randomised controlled trial (RCT).

Emery CA, van den Berg C, Richmond SA, Palacios-Derflingher L, McKay CD, Doyle-Baker PK, McKinlay M, Toomey CM, Nettel-Aguirre A, Verhagen E, Belton K, Macpherson A, Hagel BE.

Br J Sports Med. 2019 Dec 10. pii: bjsports-2019-101117. doi: 10.1136/bjsports-2019-101117. [Epub ahead of print]


Risks and benefits of unapproved disease-modifying treatments for neurodegenerative disease.

Feustel AC, MacPherson A, Fergusson DA, Kieburtz K, Kimmelman J.

Neurology. 2020 Jan 7;94(1):e1-e14. doi: 10.1212/WNL.0000000000008699. Epub 2019 Dec 2.


Anti-commensal Ig-from enormous diversity to clear function.

Rollenske T, Macpherson AJ.

Mucosal Immunol. 2020 Jan;13(1):1-2. doi: 10.1038/s41385-019-0223-8. Epub 2019 Nov 12. No abstract available.


Escherichia coli limits Salmonella Typhimurium infections after diet shifts and fat-mediated microbiota perturbation in mice.

Wotzka SY, Kreuzer M, Maier L, Arnoldini M, Nguyen BD, Brachmann AO, Berthold DL, Zünd M, Hausmann A, Bakkeren E, Hoces D, Gül E, Beutler M, Dolowschiak T, Zimmermann M, Fuhrer T, Moor K, Sauer U, Typas A, Piel J, Diard M, Macpherson AJ, Stecher B, Sunagawa S, Slack E, Hardt WD.

Nat Microbiol. 2019 Dec;4(12):2164-2174. doi: 10.1038/s41564-019-0568-5. Epub 2019 Oct 7.


Does disallowing body checking in non-elite 13- to 14-year-old ice hockey leagues reduce rates of injury and concussion? A cohort study in two Canadian provinces.

Emery C, Palacios-Derflingher L, Black AM, Eliason P, Krolikowski M, Spencer N, Kozak S, Schneider KJ, Babul S, Mrazik M, Lebrun CM, Goulet C, Macpherson A, Hagel BE.

Br J Sports Med. 2020 Apr;54(7):414-420. doi: 10.1136/bjsports-2019-101092. Epub 2019 Sep 6.


4-Methylumbelliferone Inhibits Cancer Stem Cell Activation and Overcomes Chemoresistance in Ovarian Cancer.

Lokman NA, Price ZK, Hawkins EK, Macpherson AM, Oehler MK, Ricciardelli C.

Cancers (Basel). 2019 Aug 15;11(8). pii: E1187. doi: 10.3390/cancers11081187.


Societal determinants of violent death: The extent to which social, economic, and structural characteristics explain differences in violence across Australia, Canada, and the United States.

Wilkins NJ, Zhang X, Mack KA, Clapperton AJ, Macpherson A, Sleet D, Kresnow-Sedacca MJ, Ballesteros MF, Newton D, Murdoch J, Mackay JM, Berecki-Gisolf J, Marr A, Armstead T, McClure R.

SSM Popul Health. 2019 Jul 8;8:100431. doi: 10.1016/j.ssmph.2019.100431. eCollection 2019 Aug.


Vegetarian or gluten-free diets in patients with inflammatory bowel disease are associated with lower psychological well-being and a different gut microbiota, but no beneficial effects on the course of the disease.

Schreiner P, Yilmaz B, Rossel JB, Franc Y, Misselwitz B, Scharl M, Zeitz J, Frei P, Greuter T, Vavricka SR, Pittet V, Siebenhüner A, Juillerat P, von Känel R, Macpherson AJ, Rogler G, Biedermann L; Swiss IBD Cohort Study Group.

United European Gastroenterol J. 2019 Jul;7(6):767-781. doi: 10.1177/2050640619841249. Epub 2019 Mar 27.


On-Ice Measures of External Load in Relation to Match Outcome in Elite Female Ice Hockey.

Douglas A, Johnston K, Baker J, Rotondi MA, Jamnik VK, Macpherson AK.

Sports (Basel). 2019 Jul 16;7(7). pii: E173. doi: 10.3390/sports7070173.


Impact of applying different resting blood pressure cut-points to clear for maximal exercise.

Yee EB, Macpherson A, Gledhill N, Gledhill S, Jamnik V.

Work. 2019;63(4):635-642. doi: 10.3233/WOR-192952.


Ethical development of stem-cell-based interventions.

MacPherson A, Kimmelman J.

Nat Med. 2019 Jul;25(7):1037-1044. doi: 10.1038/s41591-019-0511-6. Epub 2019 Jul 3. Review.


Cognition Predicts Mobility Change in Lower Extremity Amputees Between Discharge From Rehabilitation and 4-Month Follow-up: A Prospective Cohort Study.

Hunter SW, Bobos P, Frengopoulos C, Macpherson A, Viana R, Payne MW.

Arch Phys Med Rehabil. 2019 Nov;100(11):2129-2135. doi: 10.1016/j.apmr.2019.05.030. Epub 2019 Jun 25.


The built environment and active transportation safety in children and youth: a study protocol.

Hagel BE, Macpherson A, Howard A, Fuselli P, Cloutier MS, Winters M, Richmond SA, Rothman L, Belton K, Buliung R, Emery CA, Faulkner G, Kennedy J, Ma T, Macarthur C, McCormack GR, Morrow G, Nettel-Aguirre A, Owens L, Pike I, Russell K, Torres J, Voaklander D, Embree T, Hubka T.

BMC Public Health. 2019 Jun 11;19(1):728. doi: 10.1186/s12889-019-7024-6.


Cannabis use as a risk factor for causing motor vehicle crashes: a prospective study.

Brubacher JR, Chan H, Erdelyi S, Macdonald S, Asbridge M, Mann RE, Eppler J, Lund A, MacPherson A, Martz W, Schreiber WE, Brant R, Purssell RA.

Addiction. 2019 Sep;114(9):1616-1626. doi: 10.1111/add.14663. Epub 2019 Jul 3.


Factors associated with the timing of the first prenatal ultrasound in Canada.

Abdullah P, Landy CK, McCague H, Macpherson A, Tamim H.

BMC Pregnancy Childbirth. 2019 May 10;19(1):164. doi: 10.1186/s12884-019-2309-4.


Endoscopic rescue therapy of a distally perforated, retroperitoneal stent after EUS-guided pancreaticogastrostomy.

Maubach J, Christen S, Macpherson AJ, Worni M.

VideoGIE. 2019 Mar 4;4(4):169-171. doi: 10.1016/j.vgie.2019.01.002. eCollection 2019 Apr. No abstract available.


Reality Check! Perceptions of MTV's Jersey Shore and 16 and Pregnant/Teen Mom and Dating Violence Attitudes and Experiences.

Rodenhizer KAE, Siller L, MacPherson AR, Edwards KM.

J Interpers Violence. 2019 Apr 25:886260519844776. doi: 10.1177/0886260519844776. [Epub ahead of print]


Recent trends in child and youth emergency department visits because of pedestrian motor vehicle collisions by socioeconomic status in Ontario, Canada.

Rothman L, Macarthur C, Wilton A, Howard AW, Macpherson AK.

Inj Prev. 2019 Dec;25(6):570-573. doi: 10.1136/injuryprev-2018-043090. Epub 2019 Apr 11.


Spatial distribution of roadway environment features related to child pedestrian safety by census tract income in Toronto, Canada.

Rothman L, Cloutier MS, Manaugh K, Howard AW, Macpherson AK, Macarthur C.

Inj Prev. 2019 Apr 1. pii: injuryprev-2018-043125. doi: 10.1136/injuryprev-2018-043125. [Epub ahead of print]


Transcriptome analyses of ovarian stroma: tunica albuginea, interstitium and theca interna.

Hummitzsch K, Hatzirodos N, Macpherson AM, Schwartz J, Rodgers RJ, Irving-Rodgers HF.

Reproduction. 2019 Jun;157(6):545-565. doi: 10.1530/REP-18-0323.


Sport experience is correlated with complex motor skill recovery in youth following concussion.

Dalecki M, Gorbet DJ, Macpherson A, Sergio LE.

Eur J Sport Sci. 2019 Oct;19(9):1257-1266. doi: 10.1080/17461391.2019.1584249. Epub 2019 Mar 17.


On-Ice Physical Demands of World-Class Women's Ice Hockey: From Training to Competition.

Douglas A, Rotondi MA, Baker J, Jamnik VK, Macpherson AK.

Int J Sports Physiol Perform. 2019 Sep 2:1227-1232. doi: 10.1123/ijspp.2018-0571. [Epub ahead of print]


Publisher Correction: Microbial network disturbances in relapsing refractory Crohn's disease.

Yilmaz B, Juillerat P, Øyås O, Ramon C, Bravo FD, Franc Y, Fournier N, Michetti P, Mueller C, Geuking M, Pittet VEH, Maillard MH, Rogler G; Swiss IBD Cohort Investigators, Wiest R, Stelling J, Macpherson AJ.

Nat Med. 2019 Apr;25(4):701. doi: 10.1038/s41591-019-0411-9.


Epithelial endoplasmic reticulum stress orchestrates a protective IgA response.

Grootjans J, Krupka N, Hosomi S, Matute JD, Hanley T, Saveljeva S, Gensollen T, Heijmans J, Li H, Limenitakis JP, Ganal-Vonarburg SC, Suo S, Luoma AM, Shimodaira Y, Duan J, Shih DQ, Conner ME, Glickman JN, Fuhler GM, Palm NW, de Zoete MR, van der Woude CJ, Yuan GC, Wucherpfennig KW, Targan SR, Rosenstiel P, Flavell RA, McCoy KD, Macpherson AJ, Kaser A, Blumberg RS.

Science. 2019 Mar 1;363(6430):993-998. doi: 10.1126/science.aat7186.


Cohort Profile Update: The Swiss Inflammatory Bowel Disease Cohort Study (SIBDCS).

Pittet V, Michetti P, Mueller C, Braegger CP, von Känel R, Schoepfer A, Macpherson AJ, Rogler G; Swiss IBD Cohort Study Group.

Int J Epidemiol. 2019 Apr 1;48(2):385-386f. doi: 10.1093/ije/dyy298. No abstract available.


Microbial network disturbances in relapsing refractory Crohn's disease.

Yilmaz B, Juillerat P, Øyås O, Ramon C, Bravo FD, Franc Y, Fournier N, Michetti P, Mueller C, Geuking M, Pittet VEH, Maillard MH, Rogler G; Swiss IBD Cohort Investigators, Wiest R, Stelling J, Macpherson AJ.

Nat Med. 2019 Feb;25(2):323-336. doi: 10.1038/s41591-018-0308-z. Epub 2019 Jan 21. Erratum in: Nat Med. 2019 Apr;25(4):701.


Childhood road traffic injuries in Canada - a provincial comparison of transport injury rates over time.

Fridman L, Fraser-Thomas JL, Pike I, Macpherson AK.

BMC Public Health. 2018 Dec 6;18(1):1348. doi: 10.1186/s12889-018-6269-9.


EUS-guided hepaticojejunostomy with transjejunal per-oral cholangioscopy and electrohydraulic lithotripsy in a patient with complicated choledocholithiasis after Roux-en-Y gastric bypass.

Maubach J, Gruber M, Nett P, Macpherson AJ, Worni M.

VideoGIE. 2018 Aug 26;3(11):351-353. doi: 10.1016/j.vgie.2018.07.017. eCollection 2018 Nov. No abstract available.


Patient safety: Never say never.

Pemberton MN, Macpherson A.

Br Dent J. 2018 Oct 26;225(8):685. doi: 10.1038/sj.bdj.2018.938. No abstract available.


Endoscopic intra-abdominal rescue therapy of a dislodged EUS-guided hepaticogastrostomy stent.

Maubach J, Christen S, Macpherson AJ, Worni M.

VideoGIE. 2018 Sep 5;3(10):308-310. doi: 10.1016/j.vgie.2018.07.015. eCollection 2018 Oct. No abstract available.


Antibodies Set Boundaries Limiting Microbial Metabolite Penetration and the Resultant Mammalian Host Response.

Uchimura Y, Fuhrer T, Li H, Lawson MA, Zimmermann M, Yilmaz B, Zindel J, Ronchi F, Sorribas M, Hapfelmeier S, Ganal-Vonarburg SC, Gomez de Agüero M, McCoy KD, Sauer U, Macpherson AJ.

Immunity. 2018 Sep 18;49(3):545-559.e5. doi: 10.1016/j.immuni.2018.08.004. Epub 2018 Sep 4.


Functional Gut Microbiota Remodeling Contributes to the Caloric Restriction-Induced Metabolic Improvements.

Fabbiano S, Suárez-Zamorano N, Chevalier C, Lazarević V, Kieser S, Rigo D, Leo S, Veyrat-Durebex C, Gaïa N, Maresca M, Merkler D, Gomez de Agüero M, Macpherson A, Schrenzel J, Trajkovski M.

Cell Metab. 2018 Dec 4;28(6):907-921.e7. doi: 10.1016/j.cmet.2018.08.005. Epub 2018 Aug 30.


The effects of male harm vary with female quality and environmental complexity in Drosophila melanogaster.

MacPherson A, Yun L, Barrera TS, Agrawal AF, Rundle HD.

Biol Lett. 2018 Aug;14(8). pii: 20180443. doi: 10.1098/rsbl.2018.0443.


EUS-guided pancreaticogastrostomy and transgastric per-oral pancreatoscopy with electrohydraulic lithotripsy in a patient with chronic hereditary pancreatitis and several intraductal stones.

Maubach J, Macpherson AJ, Gloor B, Worni M.

VideoGIE. 2018 Jun 18;3(8):238-240. doi: 10.1016/j.vgie.2018.05.003. eCollection 2018 Aug. No abstract available.


Checkpoint for gut microbes after birth.

Macpherson AJ, Ganal-Vonarburg SC.

Nature. 2018 Aug;560(7719):436-438. doi: 10.1038/d41586-018-05861-z. No abstract available.


LAG3+ Regulatory T Cells Restrain Interleukin-23-Producing CX3CR1+ Gut-Resident Macrophages during Group 3 Innate Lymphoid Cell-Driven Colitis.

Bauché D, Joyce-Shaikh B, Jain R, Grein J, Ku KS, Blumenschein WM, Ganal-Vonarburg SC, Wilson DC, McClanahan TK, Malefyt RW, Macpherson AJ, Annamalai L, Yearley JH, Cua DJ.

Immunity. 2018 Aug 21;49(2):342-352.e5. doi: 10.1016/j.immuni.2018.07.007. Epub 2018 Aug 7.


D-lactic Acidosis: Successful Suppression of D-lactate-Producing Lactobacillus by Probiotics.

Yilmaz B, Schibli S, Macpherson AJ, Sokollik C.

Pediatrics. 2018 Sep;142(3). pii: e20180337. doi: 10.1542/peds.2018-0337. Epub 2018 Aug 8.


An interprovincial comparison of unintentional childhood injury rates in Canada for the period 2006-2012.

Fridman L, Fraser-Thomas J, Pike I, Macpherson AK.

Can J Public Health. 2018 Aug;109(4):573-580. doi: 10.17269/s41997-018-0112-z. Epub 2018 Aug 2.


What are the risk factors for injuries and injury prevention strategies for skiers and snowboarders in terrain parks and half-pipes? A systematic review.

Audet O, Hagel BE, Nettel-Aguirre A, Mitra T, Emery CA, Macpherson A, Lavoie MD, Goulet C.

Br J Sports Med. 2019 Jan;53(1):19-24. doi: 10.1136/bjsports-2018-099166. Epub 2018 Aug 2.


IgA-about the unexpected.

Macpherson AJ, Ganal-Vonarburg SC.

J Exp Med. 2018 Aug 6;215(8):1965-1966. doi: 10.1084/jem.20181153. Epub 2018 Jul 25.


E-cigarettes: A new hazard for children and adolescents.

Richmond SA, Pike I, Maguire JL, Macpherson A.

Paediatr Child Health. 2018 Jul;23(4):255-259. doi: 10.1093/pch/pxx204. Epub 2018 Mar 1.


The rational design of affinity-attenuated OmCI for the purification of complement C5.

Macpherson A, Liu X, Dedi N, Kennedy J, Carrington B, Durrant O, Heywood S, van den Elsen J, Lawson ADG.

J Biol Chem. 2018 Sep 7;293(36):14112-14121. doi: 10.1074/jbc.RA118.004043. Epub 2018 Jul 20.


Logarithmic scales in ecological data presentation may cause misinterpretation.

Menge DNL, MacPherson AC, Bytnerowicz TA, Quebbeman AW, Schwartz NB, Taylor BN, Wolf AA.

Nat Ecol Evol. 2018 Sep;2(9):1393-1402. doi: 10.1038/s41559-018-0610-7. Epub 2018 Jul 16.


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