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Lung clearance index and steroid response in pediatric severe asthma.

Irving S, Fleming L, Ahmad F, Biggart E, Bingham Y, Cook J, Hall P, Jamalzadeh A, Nagakumar P, Bossley C, Gupta A, Macleod K, Saglani S, Bush A.

Pediatr Pulmonol. 2020 Feb 6. doi: 10.1002/ppul.24675. [Epub ahead of print]


Pathogenic Potential of Hic1-Expressing Cardiac Stromal Progenitors.

Soliman H, Paylor B, Scott RW, Lemos DR, Chang C, Arostegui M, Low M, Lee C, Fiore D, Braghetta P, Pospichalova V, Barkauskas CE, Korinek V, Rampazzo A, MacLeod K, Underhill TM, Rossi FMV.

Cell Stem Cell. 2020 Feb 6;26(2):205-220.e8. doi: 10.1016/j.stem.2019.12.008. Epub 2020 Jan 23.


Somatic mitochondrial mutation discovery using ultra-deep sequencing of the mitochondrial genome reveals spatial tumor heterogeneity in head and neck squamous cell carcinoma.

Schubert AD, Channah Broner E, Agrawal N, London N, Pearson A, Gupta A, Wali N, Seiwert TY, Wheelan S, Lingen M, Macleod K, Allen H, Chatterjee A, Vassiliki S, Gaykalova D, Hoque MO, Sidransky D, Suresh K, Izumchenko E.

Cancer Lett. 2020 Feb 28;471:49-60. doi: 10.1016/j.canlet.2019.12.006. Epub 2019 Dec 10.


ROCK2 as a novel target for diabetic cardiomyopathy.

Soliman H, Nyamandi V, Hove-Madsen L, MacLeod KM.

Int J Cardiol. 2020 Jan 15;299:206. doi: 10.1016/j.ijcard.2019.10.017. No abstract available.


N-cadherin stabilises neural identity by dampening anti-neural signals.

Punovuori K, Migueles RP, Malaguti M, Blin G, Macleod KG, Carragher NO, Pieters T, van Roy F, Stemmler MP, Lowell S.

Development. 2019 Nov 8;146(21). pii: dev183269. doi: 10.1242/dev.183269.


Spike threshold adaptation diversifies neuronal operating modes in the auditory brain stem.

Lubejko ST, Fontaine B, Soueidan SE, MacLeod KM.

J Neurophysiol. 2019 Dec 1;122(6):2576-2590. doi: 10.1152/jn.00234.2019. Epub 2019 Oct 2.


Autophagy and cancer cell metabolism.

Anderson CM, Macleod KF.

Int Rev Cell Mol Biol. 2019;347:145-190. doi: 10.1016/bs.ircmb.2019.06.002. Epub 2019 Jul 9.


Oncogenic KRAS Induces NIX-Mediated Mitophagy to Promote Pancreatic Cancer.

Humpton TJ, Alagesan B, DeNicola GM, Lu D, Yordanov GN, Leonhardt CS, Yao MA, Alagesan P, Zaatari MN, Park Y, Skepper JN, Macleod KF, Perez-Mancera PA, Murphy MP, Evan GI, Vousden KH, Tuveson DA.

Cancer Discov. 2019 Sep;9(9):1268-1287. doi: 10.1158/2159-8290.CD-18-1409. Epub 2019 Jul 1.


Gestation alters the gut microbiota of an oviparous lizard.

Trevelline BK, MacLeod KJ, Langkilde T, Kohl KD.

FEMS Microbiol Ecol. 2019 Jul 1;95(7). pii: fiz086. doi: 10.1093/femsec/fiz086.


Mauritian Endemic Medicinal Plant Extracts Induce G2/M Phase Cell Cycle Arrest and Growth Inhibition of Oesophageal Squamous Cell Carcinoma in Vitro.

Rummun N, Hughes RE, Beesoo R, Li WW, Aldulaimi O, Macleod KG, Bahorun T, Carragher NO, Kagansky A, Neergheen-Bhujun VS.

Acta Naturae. 2019 Jan-Mar;11(1):81-90.


Simulation in surgical training: Prospective cohort study of access, attitudes and experiences of surgical trainees in the UK and Ireland.

Nicholas R, Humm G, MacLeod KE, Bathla S, Horgan A, Nally DM, Glasbey J, Clements JM, Fleming C, Mohan HM.

Int J Surg. 2019 Jul;67:94-100. doi: 10.1016/j.ijsu.2019.04.004. Epub 2019 Apr 14.


Maternal corticosterone increases thermal sensitivity of heart rate in lizard embryos.

Owen DAS, Sheriff MJ, Heppner JJ, Gerke H, Ensminger DC, MacLeod KJ, Langkilde T.

Biol Lett. 2019 Jan 31;15(1):20180718. doi: 10.1098/rsbl.2018.0718.


Glucocorticoids do not influence a secondary sexual trait or its behavioral expression in eastern fence lizards.

MacLeod KJ, McCormick GL, Langkilde T.

Sci Rep. 2019 Mar 26;9(1):5229. doi: 10.1038/s41598-019-41596-1.


Changes in cellular Ca2+ and Na+ regulation during the progression towards heart failure in the guinea pig.

Ke HY, Yang HY, Francis AJ, Collins TP, Surendran H, Alvarez-Laviada A, Firth JM, MacLeod KT.

J Physiol. 2019 Feb 27. doi: 10.1113/JP277038. [Epub ahead of print]


ROCK2 promotes ryanodine receptor phosphorylation and arrhythmic calcium release in diabetic cardiomyocytes.

Soliman H, Nyamandi V, Garcia-Patino M, Zhang PC, Lin E, Jia ZP, Tibbits GF, Hove-Madsen L, MacLeod KM.

Int J Cardiol. 2019 Apr 15;281:90-98. doi: 10.1016/j.ijcard.2019.01.075. Epub 2019 Jan 24.


Health Impact Assessment of Transportation Projects and Policies: Living Up to Aims of Advancing Population Health and Health Equity?

Cole BL, MacLeod KE, Spriggs R.

Annu Rev Public Health. 2019 Apr 1;40:305-318. doi: 10.1146/annurev-publhealth-040617-013836. Epub 2019 Jan 2.


Autophagy, cancer stem cells and drug resistance.

Smith AG, Macleod KF.

J Pathol. 2019 Apr;247(5):708-718. doi: 10.1002/path.5222. Epub 2019 Feb 4. Review.


Understanding influenza vaccination rates and reasons for refusal in caregivers and household contacts of cancer patients.

Price SA, Podczervinski S, MacLeod K, Helbert L, Pergam SA.

Am J Infect Control. 2019 Apr;47(4):468-470. doi: 10.1016/j.ajic.2018.10.010. Epub 2018 Dec 4.


Reversal of proliferation deficits caused by chromosome 16p13.11 microduplication through targeting NFκB signaling: an integrated study of patient-derived neuronal precursor cells, cerebral organoids and in vivo brain imaging.

Johnstone M, Vasistha NA, Barbu MC, Dando O, Burr K, Christopher E, Glen S, Robert C, Fetit R, Macleod KG, Livesey MR, Clair DS, Blackwood DHR, Millar K, Carragher NO, Hardingham GE, Wyllie DJA, Johnstone EC, Whalley HC, McIntosh AM, Lawrie SM, Chandran S.

Mol Psychiatry. 2019 Feb;24(2):294-311. doi: 10.1038/s41380-018-0292-1. Epub 2018 Nov 6.


Molecular reductions in glucokinase activity increase counter-regulatory responses to hypoglycemia in mice and humans with diabetes.

Chakera AJ, Hurst PS, Spyer G, Ogunnowo-Bada EO, Marsh WJ, Riches CH, Yueh CY, Markkula SP, Dalley JW, Cox RD, Macdonald IA, Amiel SA, MacLeod KM, Heisler LK, Hattersley AT, Evans ML.

Mol Metab. 2018 Nov;17:17-27. doi: 10.1016/j.molmet.2018.08.001. Epub 2018 Aug 13.


Raising awareness of sensory impairment among community nurses: a brief intervention in a remote island setting.

Smith A, Shepherd A, Macaden L, Macleod KL.

Rural Remote Health. 2018 Aug;18(3):4548. doi: 10.22605/RRH4548. Epub 2018 Aug 21.


Capillary and Venous Blood Glucose Accuracy in Blood Glucose Meters Versus Reference Standards: The Impact of Study Design on Accuracy Evaluations.

Macleod K, Katz LB, Cameron H.

J Diabetes Sci Technol. 2019 May;13(3):546-552. doi: 10.1177/1932296818790228. Epub 2018 Aug 7.


Maternal stress alters the phenotype of the mother, her eggs and her offspring in a wild-caught lizard.

Ensminger DC, Langkilde T, Owen DAS, MacLeod KJ, Sheriff MJ.

J Anim Ecol. 2018 Nov;87(6):1685-1697. doi: 10.1111/1365-2656.12891. Epub 2018 Aug 30.


In ovo microbial communities: a potential mechanism for the initial acquisition of gut microbiota among oviparous birds and lizards.

Trevelline BK, MacLeod KJ, Knutie SA, Langkilde T, Kohl KD.

Biol Lett. 2018 Jul;14(7). pii: 20180225. doi: 10.1098/rsbl.2018.0225.


Survival and reproductive costs of repeated acute glucocorticoid elevations in a captive, wild animal.

MacLeod KJ, Sheriff MJ, Ensminger DC, Owen DAS, Langkilde T.

Gen Comp Endocrinol. 2018 Nov 1;268:1-6. doi: 10.1016/j.ygcen.2018.07.006. Epub 2018 Aug 16.


Influence of school environments on childhood obesity in California.

Ortega Hinojosa AM, MacLeod KE, Balmes J, Jerrett M.

Environ Res. 2018 Oct;166:100-107. doi: 10.1016/j.envres.2018.04.022. Epub 2018 Jun 6.


High-Frequency Fe-H Vibrations in a Bridging Hydride Complex Characterized by NRVS and DFT.

Pelmenschikov V, Gee LB, Wang H, MacLeod KC, McWilliams SF, Skubi KL, Cramer SP, Holland PL.

Angew Chem Int Ed Engl. 2018 Jul 20;57(30):9367-9371. doi: 10.1002/anie.201804601. Epub 2018 Jun 25.


Postimpact earliest Paleogene warming shown by fish debris oxygen isotopes (El Kef, Tunisia).

MacLeod KG, Quinton PC, Sepúlveda J, Negra MH.

Science. 2018 Jun 29;360(6396):1467-1469. doi: 10.1126/science.aap8525. Epub 2018 May 24.


Cardiopulmonary Demand of 16-kg Kettlebell Snatches in Simulated Girevoy Sport.

Chan M, MacInnis MJ, Koch S, MacLeod KE, Lohse KR, Gallo ME, Sheel AW, Koehle MS.

J Strength Cond Res. 2018 May 17. doi: 10.1519/JSC.0000000000002588. [Epub ahead of print]


Developing an index of dose of exposure to early childhood obesity community interventions.

Wang MC, Crespi CM, Jiang LH, Nobari T, Roper-Fingerhut H, Rauzon S, Robles B, Blocklin M, Davoudi M, Kuo T, MacLeod KE, Seto E, Whaley S, Prelip M.

Prev Med. 2018 Jun;111:135-141. doi: 10.1016/j.ypmed.2018.02.036. Epub 2018 Mar 6.


Dia1-dependent adhesions are required by epithelial tissues to initiate invasion.

Fessenden TB, Beckham Y, Perez-Neut M, Ramirez-San Juan G, Chourasia AH, Macleod KF, Oakes PW, Gardel ML.

J Cell Biol. 2018 Apr 2;217(4):1485-1502. doi: 10.1083/jcb.201703145. Epub 2018 Feb 5.


Mer-mediated eosinophil efferocytosis regulates resolution of allergic airway inflammation.

Felton JM, Lucas CD, Dorward DA, Duffin R, Kipari T, Vermeren S, Robb CT, MacLeod KG, Serrels B, Schwarze J, Haslett C, Dransfield I, Rossi AG.

J Allergy Clin Immunol. 2018 Dec;142(6):1884-1893.e6. doi: 10.1016/j.jaci.2018.01.029. Epub 2018 Feb 8.


Active and dynamic mitochondrial S-depalmitoylation revealed by targeted fluorescent probes.

Kathayat RS, Cao Y, Elvira PD, Sandoz PA, Zaballa ME, Springer MZ, Drake LE, Macleod KF, van der Goot FG, Dickinson BC.

Nat Commun. 2018 Jan 23;9(1):334. doi: 10.1038/s41467-017-02655-1.


Functions of autophagy in the tumor microenvironment and cancer metastasis.

Mowers EE, Sharifi MN, Macleod KF.

FEBS J. 2018 May;285(10):1751-1766. doi: 10.1111/febs.14388. Epub 2018 Feb 1. Review.


Supine posture changes lung volumes and increases ventilation heterogeneity in cystic fibrosis.

Smith LJ, Macleod KA, Collier GJ, Horn FC, Sheridan H, Aldag I, Taylor CJ, Cunningham S, Wild JM, Horsley A.

PLoS One. 2017 Nov 27;12(11):e0188275. doi: 10.1371/journal.pone.0188275. eCollection 2017.


TRPA1-FGFR2 binding event is a regulatory oncogenic driver modulated by miRNA-142-3p.

Berrout J, Kyriakopoulou E, Moparthi L, Hogea AS, Berrout L, Ivan C, Lorger M, Boyle J, Peers C, Muench S, Gomez JE, Hu X, Hurst C, Hall T, Umamaheswaran S, Wesley L, Gagea M, Shires M, Manfield I, Knowles MA, Davies S, Suhling K, Gonzalez YT, Carragher N, Macleod K, Abbott NJ, Calin GA, Gamper N, Zygmunt PM, Timsah Z.

Nat Commun. 2017 Oct 16;8(1):947. doi: 10.1038/s41467-017-00983-w.


Hierarchical statistical techniques are necessary to draw reliable conclusions from analysis of isolated cardiomyocyte studies.

Sikkel MB, Francis DP, Howard J, Gordon F, Rowlands C, Peters NS, Lyon AR, Harding SE, MacLeod KT.

Cardiovasc Res. 2017 Dec 1;113(14):1743-1752. doi: 10.1093/cvr/cvx151.


mTOR and HDAC Inhibitors Converge on the TXNIP/Thioredoxin Pathway to Cause Catastrophic Oxidative Stress and Regression of RAS-Driven Tumors.

Malone CF, Emerson C, Ingraham R, Barbosa W, Guerra S, Yoon H, Liu LL, Michor F, Haigis M, Macleod KF, Maertens O, Cichowski K.

Cancer Discov. 2017 Dec;7(12):1450-1463. doi: 10.1158/2159-8290.CD-17-0177. Epub 2017 Sep 29.


Integrating Ecological and Evolutionary Context in the Study of Maternal Stress.

Sheriff MJ, Bell A, Boonstra R, Dantzer B, Lavergne SG, McGhee KE, MacLeod KJ, Winandy L, Zimmer C, Love OP.

Integr Comp Biol. 2017 Sep 1;57(3):437-449. doi: 10.1093/icb/icx105.


Autophagy gene ATG7 regulates ultraviolet radiation-induced inflammation and skin tumorigenesis.

Qiang L, Sample A, Shea CR, Soltani K, Macleod KF, He YY.

Autophagy. 2017;13(12):2086-2103. doi: 10.1080/15548627.2017.1380757.


Correction to "Density Functional Calculations for Prediction of 57Fe Mossbauer Isomer Shifts and Quadrupole Splittings in β-Diketiminate Complexes".

McWilliams SF, Brennan-Wydra E, MacLeod KC, Holland PL.

ACS Omega. 2017 Sep 20;2(9):5973. doi: 10.1021/acsomega.7b01252. eCollection 2017 Sep 30.


Age- and strain-related aberrant Ca2+ release is associated with sudden cardiac death in the ACTC E99K mouse model of hypertrophic cardiomyopathy.

Rowlands CT, Owen T, Lawal S, Cao S, Pandey SS, Yang HY, Song W, Wilkinson R, Alvarez-Laviada A, Gehmlich K, Marston SB, MacLeod KT.

Am J Physiol Heart Circ Physiol. 2017 Dec 1;313(6):H1213-H1226. doi: 10.1152/ajpheart.00244.2017. Epub 2017 Sep 8.


Reverse Phase Protein Arrays and Drug Discovery.

Macleod KG, Serrels B, Carragher NO.

Methods Mol Biol. 2017;1647:153-169. doi: 10.1007/978-1-4939-7201-2_10.


Epidemiology of open fractures in sport: One centre's 15-year retrospective study.

Wood AM, Robertson GAJ, MacLeod K, Porter A, Court-Brown CM.

World J Orthop. 2017 Jul 18;8(7):545-552. doi: 10.5312/wjo.v8.i7.545. eCollection 2017 Jul 18.


Effect of ovariectomy on intracellular Ca2+ regulation in guinea pig cardiomyocytes.

Yang HY, Firth JM, Francis AJ, Alvarez-Laviada A, MacLeod KT.

Am J Physiol Heart Circ Physiol. 2017 Nov 1;313(5):H1031-H1043. doi: 10.1152/ajpheart.00249.2017. Epub 2017 Aug 4.


Density Functional Calculations for Prediction of 57Fe Mössbauer Isomer Shifts and Quadrupole Splittings in β-Diketiminate Complexes.

McWilliams SF, Brennan-Wydra E, MacLeod KC, Holland PL.

ACS Omega. 2017 Jun 30;2(6):2594-2606. doi: 10.1021/acsomega.7b00595. Epub 2017 Jun 12. Erratum in: ACS Omega. 2017 Sep 20;2(9):5973.


Extremity injuries sustained by the UK military in the Iraq and Afghanistan conflicts: 2003-2014.

Chandler H, MacLeod K, Penn-Barwell JG; Severe Lower Extremity Combat Trauma (SeLECT) Study Group.

Injury. 2017 Jul;48(7):1439-1443. doi: 10.1016/j.injury.2017.05.022. Epub 2017 May 17.


Erratum: High speed sCMOS-based oblique plane microscopy applied to the study of calcium dynamics in cardiac myocytes: [J. Biophotonics 9, No. 3, 311-323 (2016)].

Sikkel MB, Kumar S, Maioli V, Rowlands C, Gordon F, Harding SE, Lyon AR, MacLeod KT, Dunsby C.

J Biophotonics. 2017 May;10(5):744-745. doi: 10.1002/jbio.201700062. Epub 2017 May 3.


Genome-wide fitness analyses of the foodborne pathogen Campylobacter jejuni in in vitro and in vivo models.

de Vries SP, Gupta S, Baig A, Wright E, Wedley A, Jensen AN, Lora LL, Humphrey S, Skovgård H, Macleod K, Pont E, Wolanska DP, L'Heureux J, Mobegi FM, Smith DGE, Everest P, Zomer A, Williams N, Wigley P, Humphrey T, Maskell DJ, Grant AJ.

Sci Rep. 2017 Apr 28;7(1):1251. doi: 10.1038/s41598-017-01133-4.


Expanding perspectives on the significance of mitophagy in cancer.

Drake LE, Springer MZ, Poole LP, Kim CJ, Macleod KF.

Semin Cancer Biol. 2017 Dec;47:110-124. doi: 10.1016/j.semcancer.2017.04.008. Epub 2017 Apr 24. Review.

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