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Items: 1 to 50 of 181

1.

Etiology and Pathogenesis of Diabetes Mellitus in Children and Adolescents.

Yau M, Maclaren NK, Sperling M.

In: Feingold KR, Anawalt B, Boyce A, Chrousos G, Dungan K, Grossman A, Hershman JM, Kaltsas G, Koch C, Kopp P, Korbonits M, McLachlan R, Morley JE, New M, Perreault L, Purnell J, Rebar R, Singer F, Trence DL, Vinik A, Wilson DP, editors. Endotext [Internet]. South Dartmouth (MA): MDText.com, Inc.; 2000-.
2018 Feb 13.

2.

Etiology and Pathogenesis of Diabetes Mellitus IN Children.

Ergun-Longmire B, Maclaren NK.

In: Feingold KR, Anawalt B, Boyce A, Chrousos G, Dungan K, Grossman A, Hershman JM, Kaltsas G, Koch C, Kopp P, Korbonits M, McLachlan R, Morley JE, New M, Perreault L, Purnell J, Rebar R, Singer F, Trence DL, Vinik A, Wilson DP, editors. Endotext [Internet]. South Dartmouth (MA): MDText.com, Inc.; 2000-.
2013 Dec 9.

3.

Whole-exome sequencing identifies novel LEPR mutations in individuals with severe early onset obesity.

Gill R, Cheung YH, Shen Y, Lanzano P, Mirza NM, Ten S, Maclaren NK, Motaghedi R, Han JC, Yanovski JA, Leibel RL, Chung WK.

Obesity (Silver Spring). 2014 Feb;22(2):576-84. doi: 10.1002/oby.20492. Epub 2013 Oct 15.

4.

Basal insulin requirements on continuous subcutaneous insulin infusion during the first 12 months after diagnosis of type 1 diabetes mellitus.

Ramchandani N, Ellis MK, Jain S, Bhandari S, Anhalt H, Maclaren NK, Ten S.

J Diabetes Sci Technol. 2010 May 1;4(3):610-4.

5.

Large islets, beta-cell proliferation, and a glucokinase mutation.

Kassem S, Bhandari S, Rodríguez-Bada P, Motaghedi R, Heyman M, García-Gimeno MA, Cobo-Vuilleumier N, Sanz P, Maclaren NK, Rahier J, Glaser B, Cuesta-Muñoz AL.

N Engl J Med. 2010 Apr 8;362(14):1348-50. doi: 10.1056/NEJMc0909845. No abstract available. Erratum in: N Engl J Med. 2010 Nov 25;363(22):2178.

6.

Interferon autoantibodies associated with AIRE deficiency decrease the expression of IFN-stimulated genes.

Kisand K, Link M, Wolff AS, Meager A, Tserel L, Org T, Murumägi A, Uibo R, Willcox N, Trebusak Podkrajsek K, Battelino T, Lobell A, Kämpe O, Lima K, Meloni A, Ergun-Longmire B, Maclaren NK, Perheentupa J, Krohn KJ, Scott HS, Husebye ES, Peterson P.

Blood. 2008 Oct 1;112(7):2657-66. doi: 10.1182/blood-2008-03-144634. Epub 2008 Jul 7.

7.

Childhood obesity and insulin resistance.

Maclaren NK, Gujral S, Ten S, Motagheti R.

Cell Biochem Biophys. 2007;48(2-3):73-8.

PMID:
17709876
8.

Insulin-like growth factor binding protein-1 to screen for insulin resistance in children.

Motaghedi R, Gujral S, Sinha S, Sison C, Ten S, Maclaren NK.

Diabetes Technol Ther. 2007 Feb;9(1):43-51.

PMID:
17316097
9.

Insulin pump therapy from the time of diagnosis of type 1 diabetes.

Ramchandani N, Ten S, Anhalt H, Sinha S, Ching J, Finkelstein A, Maclaren NK.

Diabetes Technol Ther. 2006 Dec;8(6):663-70.

PMID:
17109598
10.

Oral insulin therapy to prevent progression of immune-mediated (type 1) diabetes.

Ergun-Longmire B, Marker J, Zeidler A, Rapaport R, Raskin P, Bode B, Schatz D, Vargas A, Rogers D, Schwartz S, Malone J, Krischer J, Maclaren NK.

Ann N Y Acad Sci. 2004 Dec;1029:260-77.

PMID:
15681764
11.

Multiple autoantibodies as predictors of Type 1 diabetes in a general population.

Maclaren NK, Lan MS, Schatz D, Malone J, Notkins AL, Krischer J.

Diabetologia. 2003 Jun;46(6):873-4. Epub 2003 Jun 11. No abstract available.

PMID:
12802500
12.

NKT cells and type-1 diabetes and the "hygiene hypothesis" to explain the rising incidence rates.

Kukreja A, Maclaren NK.

Diabetes Technol Ther. 2002;4(3):323-33. Review.

PMID:
12165171
13.

Guidelines and recommendations for laboratory analysis in the diagnosis and management of diabetes mellitus.

Sacks DB, Bruns DE, Goldstein DE, Maclaren NK, McDonald JM, Parrott M.

Clin Chem. 2002 Mar;48(3):436-72.

14.

HLA-DR3 and DR4 and their relation to the incidence and progression of diabetic retinopathy.

Wong TY, Cruickshank KJ, Klein R, Klein BE, Moss SE, Palta M, Riley WJ, Maclaren NK, Vadheim CM, Rotter JI.

Ophthalmology. 2002 Feb;109(2):275-81.

PMID:
11825808
15.

Diabetes vaccines: a future to be realized.

Lin-Su K, Kukreja A, Maclaren NK.

Diabetes Technol Ther. 2001 Fall;3(3):451-61. Review.

PMID:
11762523
16.

Medical care from childhood to adulthood in type 1 and type 2 diabetes.

Costi G, Ten S, Maclaren NK.

J Endocrinol Invest. 2001 Oct;24(9):692-707. Review.

PMID:
11716156
17.

Autoantibodies and human leucocyte antigen class II in first-degree family members of Mexican-American type 1 diabetic patients.

Zeidler A, Raffel LJ, Costin G, Shaw SJ, Buchanan TA, Noble J, Rotter JI, Palmer J, Krischer JP, Wait C, Maclaren NK.

J Clin Endocrinol Metab. 2001 Oct;86(10):4957-62.

PMID:
11600569
18.

Islet cell autoimmunity in youth onset diabetes mellitus in Northern India.

Goswami R, Kochupillai N, Gupta N, Kukreja A, Lan M, Maclaren NK.

Diabetes Res Clin Pract. 2001 Jul;53(1):47-54.

PMID:
11378213
19.
20.

The human leukocyte antigen HLA DRB3*020/DQA1*0501 haplotype is associated with Graves' disease in African Americans.

Chen QY, Nadell D, Zhang XY, Kukreja A, Huang YJ, Wise J, Svec F, Richards R, Friday KE, Vargas A, Gomez R, Chalew S, Lan MS, Tomer Y, Maclaren NK.

J Clin Endocrinol Metab. 2000 Apr;85(4):1545-9.

PMID:
10770195
21.

Autoimmunity and diabetes.

Kukreja A, Maclaren NK.

J Clin Endocrinol Metab. 1999 Dec;84(12):4371-8. Review.

PMID:
10599690
22.

HLA-DRB1*08, DRB1*03/DRB3*0101, and DRB3*0202 are susceptibility genes for Graves' disease in North American Caucasians, whereas DRB1*07 is protective.

Chen QY, Huang W, She JX, Baxter F, Volpe R, Maclaren NK.

J Clin Endocrinol Metab. 1999 Sep;84(9):3182-6.

PMID:
10487684
23.

Retroviruses and autoimmune endocrine diseases.

Coutant R, MacLaren NK.

Ann Med Interne (Paris). 1999 Apr;150(3):235-44. Review. No abstract available.

PMID:
10445095
24.

Cryptic epitope and autoimmunity.

Lan MS, Maclaren NK.

Diabetes Metab Rev. 1998 Dec;14(4):333-4. No abstract available.

PMID:
10096004
25.

Association of diabetes mellitus and chronic hepatitis C virus infection.

Mason AL, Lau JY, Hoang N, Qian K, Alexander GJ, Xu L, Guo L, Jacob S, Regenstein FG, Zimmerman R, Everhart JE, Wasserfall C, Maclaren NK, Perrillo RP.

Hepatology. 1999 Feb;29(2):328-33.

PMID:
9918906
26.

HERV-K10s and immune-mediated (type 1) diabetes.

Lan MS, Mason A, Coutant R, Chen QY, Vargas A, Rao J, Gomez R, Chalew S, Garry R, Maclaren NK.

Cell. 1998 Oct 2;95(1):14-6; discussion 16. No abstract available.

27.

The gene responsible for autoimmune polyglandular syndrome type 1 maps to chromosome 21q22.3 in US patients.

Chen QY, Lan MS, She JX, Maclaren NK.

J Autoimmun. 1998 Apr;11(2):177-83.

PMID:
9650097
28.

The relationship between humoral and cellular immunity to IA-2 in IDDM.

Ellis TM, Schatz DA, Ottendorfer EW, Lan MS, Wasserfall C, Salisbury PJ, She JX, Notkins AL, Maclaren NK, Atkinson MA.

Diabetes. 1998 Apr;47(4):566-9.

PMID:
9568688
29.

Family cell lines available for research--an endangered resource?

Lernmark A, Eisenbarth G, Ducat L, Erlich HA, Faustman D, Maclaren NK, Ott J, Permutt MA, She JX, Todd J.

Am J Hum Genet. 1997 Sep;61(3):778-9. No abstract available.

30.

Insulin-dependent diabetes mellitus (IDDM) is associated with CTLA4 polymorphisms in multiple ethnic groups.

Marron MP, Raffel LJ, Garchon HJ, Jacob CO, Serrano-Rios M, Martinez Larrad MT, Teng WP, Park Y, Zhang ZX, Goldstein DR, Tao YW, Beaurain G, Bach JF, Huang HS, Luo DF, Zeidler A, Rotter JI, Yang MC, Modilevsky T, Maclaren NK, She JX.

Hum Mol Genet. 1997 Aug;6(8):1275-82.

PMID:
9259273
31.

Autoantigens in insulin-dependent diabetes mellitus: molecular cloning and characterization of human IA-2 beta.

Li Q, Borovitskaya AE, DeSilva MG, Wasserfall C, Maclaren NK, Notkins AL, Lan MS.

Proc Assoc Am Physicians. 1997 Jul;109(4):429-39.

PMID:
9220540
32.

Immunization therapies in the prevention of diabetes.

Ramiya VK, Lan MS, Wasserfall CH, Notkins AL, Maclaren NK.

J Autoimmun. 1997 Jun;10(3):287-92.

PMID:
9218756
33.
34.

Effect of oral and intravenous insulin and glutamic acid decarboxylase in NOD mice.

Ramiya VK, Shang XZ, Wasserfall CH, Maclaren NK.

Autoimmunity. 1997;26(3):139-51.

PMID:
9550282
35.

Insulin in diabetes prevention.

Ramiya VK, Maclaren NK.

Horm Res. 1997;48 Suppl 4:67-70.

PMID:
9350452
36.

Pharmacokinetics of aminoguanidine administration and effects on the diabetes frequency in nonobese diabetic mice.

Bowman MA, Simell OG, Peck AB, Cornelius J, Luchetta R, Look Z, Maclaren NK, Atkinson MA.

J Pharmacol Exp Ther. 1996 Nov;279(2):790-4.

PMID:
8930185
37.

IA-2 and IA-2 beta are major autoantigens in IDDM and the precursors of the 40 kDa and 37 kDa tryptic fragments.

Notkins AL, Lu J, Li Q, VanderVegt FP, Wasserfall C, Maclaren NK, Lan MS.

J Autoimmun. 1996 Oct;9(5):677-82.

PMID:
8933284
38.

No linkage or association of telomeric and centromeric T-cell receptor beta-chain markers with susceptibility to type 1 insulin-dependent diabetes in HLA-DR4 multiplex families.

McDermott MF, Schmidt-Wolf G, Sinha AA, Koo M, Porter MA, Briant L, Cambon-Thomsen A, Maclaren NK, Fiske D, Bertera S, Trucco M, Amos CI, McDevitt HO, Kastner DL.

Eur J Immunogenet. 1996 Oct;23(5):361-70.

PMID:
8909943
39.

Immunotherapies in diabetes.

Ramiya VK, Maclaren NK.

Trends Endocrinol Metab. 1996 Sep;7(7):252-7.

PMID:
18406756
40.

Prediabetic markers in children with stress hyperglycemia.

Bhisitkul DM, Vinik AI, Morrow AL, She JX, Shults J, Powers AC, Maclaren NK.

Arch Pediatr Adolesc Med. 1996 Sep;150(9):936-41.

PMID:
8790124
41.

Cow's milk and insulin-dependent diabetes mellitus. Innocent until proven guilty.

Schatz DA, Maclaren NK.

JAMA. 1996 Aug 28;276(8):647-8. No abstract available.

PMID:
8773639
42.

Quantitative thresholds of MHC class II I-E expressed on hemopoietically derived antigen-presenting cells in transgenic NOD/Lt mice determine level of diabetes resistance and indicate mechanism of protection.

Hanson MS, Cetkovic-Cvrlje M, Ramiya VK, Atkinson MA, Maclaren NK, Singh B, Elliott JF, Serreze DV, Leiter EH.

J Immunol. 1996 Aug 1;157(3):1279-87.

PMID:
8757636
43.

Although DR3-DQB1*0201 may be associated with multiple component diseases of the autoimmune polyglandular syndromes, the human leukocyte antigen DR4-DQB1*0302 haplotype is implicated only in beta-cell autoimmunity.

Huang W, Connor E, Rosa TD, Muir A, Schatz D, Silverstein J, Crockett S, She JX, Maclaren NK.

J Clin Endocrinol Metab. 1996 Jul;81(7):2559-63.

PMID:
8675578
44.

IA-2, a transmembrane protein of the protein tyrosine phosphatase family, is a major autoantigen in insulin-dependent diabetes mellitus.

Lan MS, Wasserfall C, Maclaren NK, Notkins AL.

Proc Natl Acad Sci U S A. 1996 Jun 25;93(13):6367-70.

45.

Antigen based therapies to prevent diabetes in NOD mice.

Ramiya VK, Shang XZ, Pharis PG, Wasserfall CH, Stabler TV, Muir AB, Schatz DA, Maclaren NK.

J Autoimmun. 1996 Jun;9(3):349-56.

PMID:
8816970
46.

The nature of autoantigens targeted in autoimmune endocrine diseases.

Song YH, Li Y, Maclaren NK.

Immunol Today. 1996 May;17(5):232-38. Review.

PMID:
8991385
47.

Confirmation of three susceptibility genes to insulin-dependent diabetes mellitus: IDDM4, IDDM5 and IDDM8.

Luo DF, Buzzetti R, Rotter JI, Maclaren NK, Raffel LJ, Nisticò L, Giovannini C, Pozzilli P, Thomson G, She JX.

Hum Mol Genet. 1996 May;5(5):693-8.

PMID:
8733139
48.

Identification of a second transmembrane protein tyrosine phosphatase, IA-2beta, as an autoantigen in insulin-dependent diabetes mellitus: precursor of the 37-kDa tryptic fragment.

Lu J, Li Q, Xie H, Chen ZJ, Borovitskaya AE, Maclaren NK, Notkins AL, Lan MS.

Proc Natl Acad Sci U S A. 1996 Mar 19;93(6):2307-11.

49.
50.

Paternally transmitted IDDM2 influences diabetes susceptibility despite biallelic expression of the insulin gene in human pancreas.

Bui MM, Luo DF, She JY, Maclaren NK, Muir A, Thomson G, She JX.

J Autoimmun. 1996 Feb;9(1):97-103.

PMID:
8845059

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