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Items: 1 to 50 of 371

1.

The factor Xa inhibitor rivaroxaban reduces cardiac dysfunction in a mouse model of myocardial infarction.

Bode MF, Auriemma AC, Grover SP, Hisada Y, Rennie A, Bode WD, Vora R, Subramaniam S, Cooley B, Andrade-Gordon P, Antoniak S, Mackman N.

Thromb Res. 2018 May 17;167:128-134. doi: 10.1016/j.thromres.2018.05.015. [Epub ahead of print]

PMID:
29843086
2.

Response by Daugherty et al to Letter Regarding Article, "Consideration of Sex Differences in Design and Reporting of Experimental Arterial Pathology Studies: A Statement From the Arteriosclerosis, Thrombosis, and Vascular Biology Council".

Daugherty A, Lu HS, Hegele RA, Mackman N, Rader DJ, Schmidt AM, Weber C.

Arterioscler Thromb Vasc Biol. 2018 Jun;38(6):e101-e102. doi: 10.1161/ATVBAHA.118.310988. No abstract available.

PMID:
29793996
3.

Tissue factor and oxidative stress.

Mackman N, Antoniak S.

Blood. 2018 May 10;131(19):2094-2095. doi: 10.1182/blood-2018-02-833673. No abstract available.

PMID:
29748170
4.

Extracellular vesicles exposing tissue factor for the prediction of venous thromboembolism in patients with cancer: A prospective cohort study.

van Es N, Hisada Y, Di Nisio M, Cesarman G, Kleinjan A, Mahé I, Otten HM, Kamphuisen PW, Berckmans RJ, Büller HR, Mackman N, Nieuwland R.

Thromb Res. 2018 Jun;166:54-59. doi: 10.1016/j.thromres.2018.04.009. Epub 2018 Apr 10.

PMID:
29656167
5.

PAR2 (Protease-Activated Receptor 2) Deficiency Attenuates Atherosclerosis in Mice.

Jones SM, Mann A, Conrad K, Saum K, Hall DE, McKinney LM, Robbins N, Thompson J, Peairs AD, Camerer E, Rayner KJ, Tranter M, Mackman N, Owens AP 3rd.

Arterioscler Thromb Vasc Biol. 2018 Jun;38(6):1271-1282. doi: 10.1161/ATVBAHA.117.310082. Epub 2018 Mar 29.

PMID:
29599135
6.

Platelet Signaling Pathways and New Inhibitors.

Grover SP, Bergmeier W, Mackman N.

Arterioscler Thromb Vasc Biol. 2018 Apr;38(4):e28-e35. doi: 10.1161/ATVBAHA.118.310224. Review. No abstract available.

PMID:
29563117
7.

Comparison of microvesicle tissue factor activity in non-cancer severely ill patients and cancer patients.

Hisada Y, Thålin C, Lundström S, Wallén H, Mackman N.

Thromb Res. 2018 May;165:1-5. doi: 10.1016/j.thromres.2018.03.001. Epub 2018 Mar 7.

PMID:
29539580
8.

Correction: Enzymatic lipid oxidation by eosinophils propagates coagulation, hemostasis, and thrombotic disease.

Uderhardt S, Ackermann JA, Fillep T, Hammond VJ, Willeit J, Santer P, Mayr M, Biburger M, Miller M, Zellner KR, Stark K, Zarbock A, Rossaint J, Schubert I, Mielenz D, Dietel B, Raaz-Schrauder D, Ay C, Gremmel T, Thaler J, Heim C, Herrmann M, Collins PW, Schabbauer G, Mackman N, Voehringer D, Nadler JL, Lee JJ, Massberg S, Rauh M, Kiechl S, Schett G, O'Donnell VB, Krönke G.

J Exp Med. 2018 Mar 5;215(3):1003. doi: 10.1084/jem.2016107002142018c. Epub 2018 Feb 20. No abstract available.

9.

Dual Anticoagulant and Antiplatelet Therapy for Coronary Artery Disease and Peripheral Artery Disease Patients.

Mackman N, Spronk HMH, Stouffer GA, Ten Cate H.

Arterioscler Thromb Vasc Biol. 2018 Apr;38(4):726-732. doi: 10.1161/ATVBAHA.117.310048. Epub 2018 Feb 15. Review. No abstract available.

PMID:
29449336
10.

Tissue Factor: An Essential Mediator of Hemostasis and Trigger of Thrombosis.

Grover SP, Mackman N.

Arterioscler Thromb Vasc Biol. 2018 Apr;38(4):709-725. doi: 10.1161/ATVBAHA.117.309846. Epub 2018 Feb 8. Review.

PMID:
29437578
11.

Androgen receptor dampens tissue factor expression via nuclear factor-κB and early growth response protein 1.

Hoesel B, Mussbacher M, Dikorman B, Salzmann M, Assinger A, Hell L, Thaler J, Basílio J, Moser B, Resch U, Paar H, Mackman N, Schmid JA.

J Thromb Haemost. 2018 Apr;16(4):749-758. doi: 10.1111/jth.13971. Epub 2018 Mar 13.

PMID:
29427323
12.

Distinct Pathogenesis of Pancreatic Cancer Microvesicle-Associated Venous Thrombosis Identifies New Antithrombotic Targets In Vivo.

Stark K, Schubert I, Joshi U, Kilani B, Hoseinpour P, Thakur M, Grünauer P, Pfeiler S, Schmidergall T, Stockhausen S, Bäumer M, Chandraratne S, von Brühl ML, Lorenz M, Coletti R, Reese S, Laitinen I, Wörmann SM, Algül H, Bruns CJ, Ware J, Mackman N, Engelmann B, Massberg S.

Arterioscler Thromb Vasc Biol. 2018 Apr;38(4):772-786. doi: 10.1161/ATVBAHA.117.310262. Epub 2018 Feb 1.

PMID:
29419408
13.

Atherothrombosis and Thromboembolism: Position Paper from the Second Maastricht Consensus Conference on Thrombosis.

Spronk HMH, Padro T, Siland JE, Prochaska JH, Winters J, van der Wal AC, Posthuma JJ, Lowe G, d'Alessandro E, Wenzel P, Coenen DM, Reitsma PH, Ruf W, van Gorp RH, Koenen RR, Vajen T, Alshaikh NA, Wolberg AS, Macrae FL, Asquith N, Heemskerk J, Heinzmann A, Moorlag M, Mackman N, van der Meijden P, Meijers JCM, Heestermans M, Renné T, Dólleman S, Chayouâ W, Ariëns RAS, Baaten CC, Nagy M, Kuliopulos A, Posma JJ, Harrison P, Vries MJ, Crijns HJGM, Dudink EAMP, Buller HR, Henskens YMC, Själander A, Zwaveling S, Erküner O, Eikelboom JW, Gulpen A, Peeters FECM, Douxfils J, Olie RH, Baglin T, Leader A, Schotten U, Scaf B, van Beusekom HMM, Mosnier LO, van der Vorm L, Declerck P, Visser M, Dippel DWJ, Strijbis VJ, Pertiwi K, Ten Cate-Hoek AJ, Ten Cate H.

Thromb Haemost. 2018 Feb;118(2):229-250. doi: 10.1160/TH17-07-0492. Epub 2018 Jan 29.

PMID:
29378352
14.

Association of D-dimer with Plaque Characteristics and Plasma Biomarkers of Oxidation-Specific Epitopes in Stable Subjects with Coronary Artery Disease.

Kothari H, Nguyen AT, Yang X, Hisada Y, Tsimikas S, Mackman N, Taylor A, McNamara CA.

J Cardiovasc Transl Res. 2018 Jun;11(3):221-229. doi: 10.1007/s12265-018-9790-4. Epub 2018 Jan 17.

PMID:
29344841
15.

Mouse models of cancer-associated thrombosis.

Hisada Y, Mackman N.

Thromb Res. 2018 Apr;164 Suppl 1:S48-S53. doi: 10.1016/j.thromres.2017.12.018. Epub 2017 Dec 29.

16.

Caspase Inhibition Reduces Hepatic Tissue Factor-Driven Coagulation In Vitro and In Vivo.

Kopec AK, Spada AP, Contreras PC, Mackman N, Luyendyk JP.

Toxicol Sci. 2018 Apr 1;162(2):396-405. doi: 10.1093/toxsci/kfx268.

PMID:
29228388
17.

Human pancreatic tumors grown in mice release tissue factor-positive microvesicles that increase venous clot size.

Hisada Y, Ay C, Auriemma AC, Cooley BC, Mackman N.

J Thromb Haemost. 2017 Nov;15(11):2208-2217. doi: 10.1111/jth.13809. Epub 2017 Sep 20.

PMID:
28834179
18.

Cancer-associated pathways and biomarkers of venous thrombosis.

Hisada Y, Mackman N.

Blood. 2017 Sep 28;130(13):1499-1506. doi: 10.1182/blood-2017-03-743211. Epub 2017 Aug 14. Review.

PMID:
28807983
19.

Thrombin promotes diet-induced obesity through fibrin-driven inflammation.

Kopec AK, Abrahams SR, Thornton S, Palumbo JS, Mullins ES, Divanovic S, Weiler H, Owens AP 3rd, Mackman N, Goss A, van Ryn J, Luyendyk JP, Flick MJ.

J Clin Invest. 2017 Aug 1;127(8):3152-3166. doi: 10.1172/JCI92744. Epub 2017 Jul 24.

20.

A monocyte-TNF-endothelial activation axis in sickle transgenic mice: Therapeutic benefit from TNF blockade.

Solovey A, Somani A, Belcher JD, Milbauer L, Vincent L, Pawlinski R, Nath KA, Kelm RJ Jr, Mackman N, O'Sullivan MG, Gupta K, Vercellotti GM, Hebbel RP.

Am J Hematol. 2017 Nov;92(11):1119-1130. doi: 10.1002/ajh.24856. Epub 2017 Jul 29.

21.

Factor XI-deficient mice exhibit increased bleeding after injury to the saphenous vein.

Ay C, Hisada Y, Cooley BC, Mackman N.

J Thromb Haemost. 2017 Sep;15(9):1829-1833. doi: 10.1111/jth.13766. Epub 2017 Aug 5.

PMID:
28677246
22.

Enzymatic lipid oxidation by eosinophils propagates coagulation, hemostasis, and thrombotic disease.

Uderhardt S, Ackermann JA, Fillep T, Hammond VJ, Willeit J, Santer P, Mayr M, Biburger M, Miller M, Zellner KR, Stark K, Zarbock A, Rossaint J, Schubert I, Mielenz D, Dietel B, Raaz-Schrauder D, Ay C, Gremmel T, Thaler J, Heim C, Herrmann M, Collins PW, Schabbauer G, Mackman N, Voehringer D, Nadler JL, Lee JJ, Massberg S, Rauh M, Kiechl S, Schett G, O'Donnell VB, Krönke G.

J Exp Med. 2017 Jul 3;214(7):2121-2138. doi: 10.1084/jem.20161070. Epub 2017 May 31. Erratum in: J Exp Med. 2018 Feb 20;:.

23.

Myeloid but not epithelial tissue factor exerts protective anti-inflammatory effects in acid aspiration-induced acute lung injury.

Kral-Pointner JB, Schrottmaier WC, Horvath V, Datler H, Hell L, Ay C, Niederreiter B, Jilma B, Schmid JA, Assinger A, Mackman N, Knapp S, Schabbauer G.

J Thromb Haemost. 2017 Aug;15(8):1625-1639. doi: 10.1111/jth.13737. Epub 2017 Jun 20.

24.

Evaluation of venous thrombosis and tissue factor in epithelial ovarian cancer.

Cohen JG, Prendergast E, Geddings JE, Walts AE, Agadjanian H, Hisada Y, Karlan BY, Mackman N, Walsh CS.

Gynecol Oncol. 2017 Jul;146(1):146-152. doi: 10.1016/j.ygyno.2017.04.021. Epub 2017 May 10.

PMID:
28501328
25.

Methodological Guidelines to Study Extracellular Vesicles.

Coumans FAW, Brisson AR, Buzas EI, Dignat-George F, Drees EEE, El-Andaloussi S, Emanueli C, Gasecka A, Hendrix A, Hill AF, Lacroix R, Lee Y, van Leeuwen TG, Mackman N, Mäger I, Nolan JP, van der Pol E, Pegtel DM, Sahoo S, Siljander PRM, Sturk G, de Wever O, Nieuwland R.

Circ Res. 2017 May 12;120(10):1632-1648. doi: 10.1161/CIRCRESAHA.117.309417. Review.

26.

Detection of tissue factor-positive extracellular vesicles by laser scanning confocal microscopy.

Hisada Y, Auriemma AC, Alexander W, Ay C, Mackman N.

Thromb Res. 2017 Feb;150:65-72. doi: 10.1016/j.thromres.2016.12.021. Epub 2016 Dec 23.

PMID:
28043041
27.

Tissue Factor: Catch Me If You Can!

Ay C, Mackman N.

J Clin Oncol. 2017 Apr 1;35(10):1128-1130. doi: 10.1200/JCO.2016.70.6788. Epub 2016 Dec 28. No abstract available.

PMID:
28029321
28.

Anticoagulation increases alveolar hemorrhage in mice infected with influenza A.

Tatsumi K, Antoniak S, Subramaniam S, Gondouin B, Neidich SD, Beck MA, Mickelson J, Monroe DM 3rd, Bastarache JA, Mackman N.

Physiol Rep. 2016 Dec;4(24). pii: e13071. doi: 10.14814/phy2.13071.

29.

Erratum to "A combined deficiency of tissue factor and PAR-4 is associated with fatal pulmonary hemorrhage in mice" [Thromb. Res. 146 (2016) 46-50].

Bode MF, Mackman N.

Thromb Res. 2017 Jan;149:95. doi: 10.1016/j.thromres.2016.11.005. Epub 2016 Nov 24. No abstract available.

30.

Protease-Activated Receptor 1 Contributes to Angiotensin II-Induced Cardiovascular Remodeling and Inflammation.

Antoniak S, Cardenas JC, Buczek LJ, Church FC, Mackman N, Pawlinski R.

Cardiology. 2017;136(4):258-268. doi: 10.1159/000452269. Epub 2016 Nov 24.

31.

Protease-Activated Receptor 1 Enhances Poly I:C Induction of the Antiviral Response in Macrophages and Mice.

Antoniak S, Tatsumi K, Bode M, Vanja S, Williams JC, Mackman N.

J Innate Immun. 2017;9(2):181-192. doi: 10.1159/000450853. Epub 2016 Nov 8.

32.

Letter to Editor response: Endothelial cell tissue factor and coagulation.

Antoniak S, Mackman N.

Trends Cardiovasc Med. 2017 Feb;27(2):157. doi: 10.1016/j.tcm.2016.09.012. Epub 2016 Oct 5. No abstract available.

PMID:
27769630
33.

Corrigendum to "Measurement of microparticle tissue factor activity in clinical samples: A summary of two tissue factor-dependent FXa generation assays" [Thromb. Res. 139 (2016) 90-97].

Hisada Y, Alexander W, Kasthuri R, Voorhees P, Mobarrez F, Taylor A, McNamara C, Wallen H, MarcoWitkowski, Key NS, Rauch U, Mackman N.

Thromb Res. 2016 Nov;147:63. doi: 10.1016/j.thromres.2016.09.009. Epub 2016 Sep 24. No abstract available.

PMID:
27676256
34.

Corrigendum to 'Microvesicle-associated tissue factor procoagulant activity for the preoperative diagnosis of ovarian cancer", [Thromb. Res. 141 (2016) 39-48].

Claussen C, Rausch AV, Lezius S, Amirkhosravi A, Davila M, Francis JL, Hisada YM, Mackman N, Bokemeyer C, Schmalfeldt B, Mahner S, Langer F.

Thromb Res. 2016 Oct;146:135. doi: 10.1016/j.thromres.2016.09.008. Epub 2016 Sep 16. No abstract available.

PMID:
27640329
35.

A combined deficiency of tissue factor and PAR-4 is associated with fatal pulmonary hemorrhage in mice.

Bode MF, Mackman N.

Thromb Res. 2016 Oct;146:46-50. doi: 10.1016/j.thromres.2016.08.023. Epub 2016 Aug 22. Erratum in: Thromb Res. 2017 Jan;149:95.

36.

Thrombosis in Cancer: Research Priorities Identified by a National Cancer Institute/National Heart, Lung, and Blood Institute Strategic Working Group.

Key NS, Khorana AA, Mackman N, McCarty OJ, White GC, Francis CW, McCrae KR, Palumbo JS, Raskob GE, Chan AT, Sood AK.

Cancer Res. 2016 Jul 1;76(13):3671-5. doi: 10.1158/0008-5472.CAN-15-3100. Epub 2016 Jun 20.

37.

Protective and detrimental effects of neuroectodermal cell-derived tissue factor in mouse models of stroke.

Wang S, Reeves B, Sparkenbaugh EM, Russell J, Soltys Z, Zhang H, Faber JE, Key NS, Kirchhofer D, Granger DN, Mackman N, Pawlinski R.

JCI Insight. 2016 Jul 21;1(11). pii: e86663.

38.

Complying With the National Institutes of Health Guidelines and Principles for Rigor and Reproducibility: Refutations.

Daugherty A, Hegele RA, Mackman N, Rader DJ, Schmidt AM, Weber C.

Arterioscler Thromb Vasc Biol. 2016 Jul;36(7):1303-4. doi: 10.1161/ATVBAHA.116.307906. No abstract available.

39.

Mouse models of venous thrombosis are not equal.

Mackman N.

Blood. 2016 May 26;127(21):2510-1. doi: 10.1182/blood-2016-03-704270. No abstract available.

40.

Hemodynamics associated with atrial fibrillation directly alters thrombotic potential of endothelial cells.

Simmers MB, Cole BK, Ogletree ML, Chen Z, Xu Y, Kong LJ, Mackman N, Blackman BR, Wamhoff BR.

Thromb Res. 2016 Jul;143:34-9. doi: 10.1016/j.thromres.2016.04.022. Epub 2016 Apr 27.

PMID:
27179130
41.

OC-04 - Tissue factor positive microvesicles activate platelets in vitro and in vivo and enhance thrombosis in mice.

Hisada Y, Geddings JE, Boulaftali Y, Getz TM, Whelihan M, Fuentes R, Dee R, Cooley BC, Key NS, Wolberg AS, Bergmeier W, Mackman N.

Thromb Res. 2016 Apr;140 Suppl 1:S169-70. doi: 10.1016/S0049-3848(16)30121-9. Epub 2016 Apr 8.

PMID:
27161676
42.

Animal Models of Thrombosis From Zebrafish to Nonhuman Primates: Use in the Elucidation of New Pathologic Pathways and the Development of Antithrombotic Drugs.

Jagadeeswaran P, Cooley BC, Gross PL, Mackman N.

Circ Res. 2016 Apr 29;118(9):1363-79. doi: 10.1161/CIRCRESAHA.115.306823. Review.

43.

CalDAG-GEFI Deficiency Reduces Atherosclerotic Lesion Development in Mice.

Boulaftali Y, Owens AP 3rd, Beale A, Piatt R, Casari C, Lee RH, Conley PB, Paul DS, Mackman N, Bergmeier W.

Arterioscler Thromb Vasc Biol. 2016 May;36(5):792-9. doi: 10.1161/ATVBAHA.115.306347. Epub 2016 Mar 17.

44.

Microvesicle-associated tissue factor procoagulant activity for the preoperative diagnosis of ovarian cancer.

Claussen C, Rausch AV, Lezius S, Amirkhosravi A, Davila M, Francis JL, Hisada YM, Mackman N, Bokemeyer C, Schmalfeldt B, Mahner S, Langer F.

Thromb Res. 2016 May;141:39-48. doi: 10.1016/j.thromres.2016.03.002. Epub 2016 Mar 2. Erratum in: Thromb Res. 2016 Oct;146:135.

PMID:
26967531
45.

Antibody-based targeting of alternatively spliced tissue factor: a new approach to impede the primary growth and spread of pancreatic ductal adenocarcinoma.

Unruh D, Ünlü B, Lewis CS, Qi X, Chu Z, Sturm R, Keil R, Ahmad SA, Sovershaev T, Adam M, Van Dreden P, Woodhams BJ, Ramchandani D, Weber GF, Rak JW, Wolberg AS, Mackman N, Versteeg HH, Bogdanov VY.

Oncotarget. 2016 May 3;7(18):25264-75. doi: 10.18632/oncotarget.7955.

46.

Tissue factor deficiency increases alveolar hemorrhage and death in influenza A virus-infected mice.

Antoniak S, Tatsumi K, Hisada Y, Milner JJ, Neidich SD, Shaver CM, Pawlinski R, Beck MA, Bastarache JA, Mackman N.

J Thromb Haemost. 2016 Jun;14(6):1238-48. doi: 10.1111/jth.13307. Epub 2016 Apr 5. Erratum in: J Thromb Haemost. 2016 Dec;14 (12 ):2565.

47.

Myeloid tissue factor does not modulate lung inflammation or permeability during experimental acute lung injury.

Shaver CM, Grove BS, Clune JK, Mackman N, Ware LB, Bastarache JA.

Sci Rep. 2016 Feb 29;6:22249. doi: 10.1038/srep22249.

48.

Measurement of microparticle tissue factor activity in clinical samples: A summary of two tissue factor-dependent FXa generation assays.

Hisada Y, Alexander W, Kasthuri R, Voorhees P, Mobarrez F, Taylor A, McNamara C, Wallen H, Witkowski M, Key NS, Rauch U, Mackman N.

Thromb Res. 2016 Mar;139:90-7. doi: 10.1016/j.thromres.2016.01.011. Epub 2016 Jan 18. Review.

PMID:
26916302
49.

The Clot Thickens in Atherosclerosis.

Mackman N.

Arterioscler Thromb Vasc Biol. 2016 Mar;36(3):425-6. doi: 10.1161/ATVBAHA.116.307094. No abstract available.

50.

Is leukocyte tissue factor the key to venous thrombosis in antiphospholipid syndrome?

Mackman N, Roubey RA.

J Thromb Haemost. 2016 May;14(5):1008-10. doi: 10.1111/jth.13296. Epub 2016 Mar 21. No abstract available.

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