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Items: 1 to 50 of 54

1.

Exploiting Correlations between Protein Abundance and the Functional Status of saeRS and sarA To Identify Virulence Factors of Potential Importance in the Pathogenesis of Staphylococcus aureus Osteomyelitis.

Ramirez AM, Byrum SD, Beenken KE, Washam C, Edmondson RD, Mackintosh SG, Spencer HJ, Tackett AJ, Smeltzer MS.

ACS Infect Dis. 2019 Nov 26. doi: 10.1021/acsinfecdis.9b00291. [Epub ahead of print]

PMID:
31722523
2.

Identification of Serum Biomarkers to Distinguish Hazardous and Benign Aminotransferase Elevations.

Vazquez JH, Clemens MM, Allard FD, Yee EU, Kennon-McGill S, Mackintosh SG, Jaeschke H, Hambuchen MD, McGill MR.

Toxicol Sci. 2019 Oct 25. pii: kfz222. doi: 10.1093/toxsci/kfz222. [Epub ahead of print]

PMID:
31651977
3.

PHF19 promotes multiple myeloma tumorigenicity through PRC2 activation and broad H3K27me3 domain formation.

Ren Z, Ahn JH, Liu H, Tsai YH, Bhanu NV, Koss B, Allison DF, Ma A, Storey AJ, Wang P, Mackintosh SG, Edmondson RD, Groen RWJ, Martens AC, Garcia BA, Tackett AJ, Jin J, Cai L, Zheng D, Wang GG.

Blood. 2019 Oct 3;134(14):1176-1189. doi: 10.1182/blood.2019000578. Epub 2019 Aug 5.

PMID:
31383640
4.

Musashi interaction with poly(A)-binding protein is required for activation of target mRNA translation.

Cragle CE, MacNicol MC, Byrum SD, Hardy LL, Mackintosh SG, Richardson WA, Gray NK, Childs GV, Tackett AJ, MacNicol AM.

J Biol Chem. 2019 Jul 12;294(28):10969-10986. doi: 10.1074/jbc.RA119.007220. Epub 2019 May 31.

PMID:
31152063
5.

Metabolic reprogramming toward oxidative phosphorylation identifies a therapeutic target for mantle cell lymphoma.

Zhang L, Yao Y, Zhang S, Liu Y, Guo H, Ahmed M, Bell T, Zhang H, Han G, Lorence E, Badillo M, Zhou S, Sun Y, Di Francesco ME, Feng N, Haun R, Lan R, Mackintosh SG, Mao X, Song X, Zhang J, Pham LV, Lorenzi PL, Marszalek J, Heffernan T, Draetta G, Jones P, Futreal A, Nomie K, Wang L, Wang M.

Sci Transl Med. 2019 May 8;11(491). pii: eaau1167. doi: 10.1126/scitranslmed.aau1167.

PMID:
31068440
6.

Local and Relayed Effects of Deep Brain Stimulation of the Pedunculopontine Nucleus.

Garcia-Rill E, Tackett AJ, Byrum SD, Lan RS, Mackintosh SG, Hyde JR, Bisagno V, Urbano FJ.

Brain Sci. 2019 Mar 18;9(3). pii: E64. doi: 10.3390/brainsci9030064. Review.

7.

DEAD-box RNA helicases Dbp2, Ded1 and Mss116 bind to G-quadruplex nucleic acids and destabilize G-quadruplex RNA.

Gao J, Byrd AK, Zybailov BL, Marecki JC, Guderyon MJ, Edwards AD, Chib S, West KL, Waldrip ZJ, Mackintosh SG, Gao Z, Putnam AA, Jankowsky E, Raney KD.

Chem Commun (Camb). 2019 Apr 11;55(31):4467-4470. doi: 10.1039/c8cc10091h.

PMID:
30855040
8.

Proteomic characterization of the arsenic response locus in S. cerevisiae.

West KL, Byrum SD, Mackintosh SG, Edmondson RD, Taverna SD, Tackett AJ.

Epigenetics. 2019 Feb;14(2):130-145. doi: 10.1080/15592294.2019.1580110. Epub 2019 Mar 1.

PMID:
30739529
9.

Metaproteomics reveals potential mechanisms by which dietary resistant starch supplementation attenuates chronic kidney disease progression in rats.

Zybailov BL, Glazko GV, Rahmatallah Y, Andreyev DS, McElroy T, Karaduta O, Byrum SD, Orr L, Tackett AJ, Mackintosh SG, Edmondson RD, Kieffer DA, Martin RJ, Adams SH, Vaziri ND, Arthur JM.

PLoS One. 2019 Jan 30;14(1):e0199274. doi: 10.1371/journal.pone.0199274. eCollection 2019.

10.

Loss of E-Cadherin Inhibits CD103 Antitumor Activity and Reduces Checkpoint Blockade Responsiveness in Melanoma.

Shields BD, Koss B, Taylor EM, Storey AJ, West KL, Byrum SD, Mackintosh SG, Edmondson R, Mahmoud F, Shalin SC, Tackett AJ.

Cancer Res. 2019 Mar 15;79(6):1113-1123. doi: 10.1158/0008-5472.CAN-18-1722. Epub 2019 Jan 23.

PMID:
30674537
11.

Label-Free Proteomic Approach to Characterize Protease-Dependent and -Independent Effects of sarA Inactivation on the Staphylococcus aureus Exoproteome.

Byrum SD, Loughran AJ, Beenken KE, Orr LM, Storey AJ, Mackintosh SG, Edmondson RD, Tackett AJ, Smeltzer MS.

J Proteome Res. 2018 Oct 5;17(10):3384-3395. doi: 10.1021/acs.jproteome.8b00288. Epub 2018 Sep 27.

12.

Oxidation resistance 1 is a novel senolytic target.

Zhang X, Zhang S, Liu X, Wang Y, Chang J, Zhang X, Mackintosh SG, Tackett AJ, He Y, Lv D, Laberge RM, Campisi J, Wang J, Zheng G, Zhou D.

Aging Cell. 2018 Aug;17(4):e12780. doi: 10.1111/acel.12780. Epub 2018 May 15.

13.

Vulvar squamous cell carcinoma aggressiveness is associated with differential expression of collagen and STAT1.

Holthoff ER, Byrum SD, Mackintosh SG, Kelly T, Tackett AJ, Quick CM, Post SR.

Clin Proteomics. 2017 Dec 6;14:40. doi: 10.1186/s12014-017-9175-8. eCollection 2017.

14.

Indicators of responsiveness to immune checkpoint inhibitors.

Shields BD, Mahmoud F, Taylor EM, Byrum SD, Sengupta D, Koss B, Baldini G, Ransom S, Cline K, Mackintosh SG, Edmondson RD, Shalin S, Tackett AJ.

Sci Rep. 2017 Apr 11;7(1):807. doi: 10.1038/s41598-017-01000-2.

15.

Time- and radiation-dose dependent changes in the plasma proteome after total body irradiation of non-human primates: Implications for biomarker selection.

Byrum SD, Burdine MS, Orr L, Mackintosh SG, Authier S, Pouliot M, Hauer-Jensen M, Tackett AJ.

PLoS One. 2017 Mar 28;12(3):e0174771. doi: 10.1371/journal.pone.0174771. eCollection 2017.

16.

KDM5 lysine demethylases are involved in maintenance of 3'UTR length.

Blair LP, Liu Z, Labitigan RL, Wu L, Zheng D, Xia Z, Pearson EL, Nazeer FI, Cao J, Lang SM, Rines RJ, Mackintosh SG, Moore CL, Li W, Tian B, Tackett AJ, Yan Q.

Sci Adv. 2016 Nov 18;2(11):e1501662. doi: 10.1126/sciadv.1501662. eCollection 2016 Nov.

17.

1,3-Butadiene-induced mitochondrial dysfunction is correlated with mitochondrial CYP2E1 activity in Collaborative Cross mice.

Hartman JH, Miller GP, Caro AA, Byrum SD, Orr LM, Mackintosh SG, Tackett AJ, MacMillan-Crow LA, Hallberg LM, Ameredes BT, Boysen G.

Toxicology. 2017 Mar 1;378:114-124. doi: 10.1016/j.tox.2017.01.005. Epub 2017 Jan 9.

18.

Proteins that accumulate with age in human skeletal-muscle aggregates contribute to declines in muscle mass and function in Caenorhabditis elegans.

Ayyadevara S, Balasubramaniam M, Suri P, Mackintosh SG, Tackett AJ, Sullivan DH, Shmookler Reis RJ, Dennis RA.

Aging (Albany NY). 2016 Dec 15;8(12):3486-3497. doi: 10.18632/aging.101141.

19.

PLEKHM1/DEF8/RAB7 complex regulates lysosome positioning and bone homeostasis.

Fujiwara T, Ye S, Castro-Gomes T, Winchell CG, Andrews NW, Voth DE, Varughese KI, Mackintosh SG, Feng Y, Pavlos N, Nakamura T, Manolagas SC, Zhao H.

JCI Insight. 2016 Oct 20;1(17):e86330. doi: 10.1172/jci.insight.86330.

20.

Mitotic arrest-induced phosphorylation of Mcl-1 revisited using two-dimensional gel electrophoresis and phosphoproteomics: nine phosphorylation sites identified.

Chu R, Alford SE, Hart K, Kothari A, Mackintosh SG, Kovak MR, Chambers TC.

Oncotarget. 2016 Nov 29;7(48):78958-78970. doi: 10.18632/oncotarget.12586.

21.

Proteins that mediate protein aggregation and cytotoxicity distinguish Alzheimer's hippocampus from normal controls.

Ayyadevara S, Balasubramaniam M, Parcon PA, Barger SW, Griffin WS, Alla R, Tackett AJ, Mackintosh SG, Petricoin E, Zhou W, Shmookler Reis RJ.

Aging Cell. 2016 Oct;15(5):924-39. doi: 10.1111/acel.12501. Epub 2016 Jul 23.

22.

PIP3-binding proteins promote age-dependent protein aggregation and limit survival in C. elegans.

Ayyadevara S, Balasubramaniam M, Johnson J, Alla R, Mackintosh SG, Shmookler Reis RJ.

Oncotarget. 2016 Aug 2;7(31):48870-48886. doi: 10.18632/oncotarget.10549.

23.

Evidence That G-quadruplex DNA Accumulates in the Cytoplasm and Participates in Stress Granule Assembly in Response to Oxidative Stress.

Byrd AK, Zybailov BL, Maddukuri L, Gao J, Marecki JC, Jaiswal M, Bell MR, Griffin WC, Reed MR, Chib S, Mackintosh SG, MacNicol AM, Baldini G, Eoff RL, Raney KD.

J Biol Chem. 2016 Aug 19;291(34):18041-57. doi: 10.1074/jbc.M116.718478. Epub 2016 Jul 1.

24.

ATXN7L3 and ENY2 Coordinate Activity of Multiple H2B Deubiquitinases Important for Cellular Proliferation and Tumor Growth.

Atanassov BS, Mohan RD, Lan X, Kuang X, Lu Y, Lin K, McIvor E, Li W, Zhang Y, Florens L, Byrum SD, Mackintosh SG, Calhoun-Davis T, Koutelou E, Wang L, Tang DG, Tackett AJ, Washburn MP, Workman JL, Dent SY.

Mol Cell. 2016 May 19;62(4):558-71. doi: 10.1016/j.molcel.2016.03.030. Epub 2016 Apr 28.

25.

Sc65-Null Mice Provide Evidence for a Novel Endoplasmic Reticulum Complex Regulating Collagen Lysyl Hydroxylation.

Heard ME, Besio R, Weis M, Rai J, Hudson DM, Dimori M, Zimmerman SM, Kamykowski JA, Hogue WR, Swain FL, Burdine MS, Mackintosh SG, Tackett AJ, Suva LJ, Eyre DR, Morello R.

PLoS Genet. 2016 Apr 27;12(4):e1006002. doi: 10.1371/journal.pgen.1006002. eCollection 2016 Apr.

26.

DNA methylation on N(6)-adenine in mammalian embryonic stem cells.

Wu TP, Wang T, Seetin MG, Lai Y, Zhu S, Lin K, Liu Y, Byrum SD, Mackintosh SG, Zhong M, Tackett A, Wang G, Hon LS, Fang G, Swenberg JA, Xiao AZ.

Nature. 2016 Apr 21;532(7599):329-33. doi: 10.1038/nature17640. Epub 2016 Mar 30.

27.

Human papillomavirus type 16 viral load is decreased following a therapeutic vaccination.

Coleman HN, Greenfield WW, Stratton SL, Vaughn R, Kieber A, Moerman-Herzog AM, Spencer HJ, Hitt WC, Quick CM, Hutchins LF, Mackintosh SG, Edmondson RD, Erickson SW, Nakagawa M.

Cancer Immunol Immunother. 2016 May;65(5):563-73. doi: 10.1007/s00262-016-1821-x. Epub 2016 Mar 15.

28.

Age- and Hypertension-Associated Protein Aggregates in Mouse Heart Have Similar Proteomic Profiles.

Ayyadevara S, Mercanti F, Wang X, Mackintosh SG, Tackett AJ, Prayaga SV, Romeo F, Shmookler Reis RJ, Mehta JL.

Hypertension. 2016 May;67(5):1006-13. doi: 10.1161/HYPERTENSIONAHA.115.06849. Epub 2016 Mar 14.

29.

A Quantitative Proteomic Analysis of Urine from Gamma-Irradiated Non-Human Primates.

Byrum SD, Burdine MS, Orr L, Moreland L, Mackintosh SG, Authier S, Pouliot M, Hauer-Jensen M, Tackett AJ.

J Proteomics Bioinform. 2016;9(Suppl 10). pii: 005. Epub 2015 Dec 28.

30.

Quantitative Histone Mass Spectrometry Identifies Elevated Histone H3 Lysine 27 (Lys27) Trimethylation in Melanoma.

Sengupta D, Byrum SD, Avaritt NL, Davis L, Shields B, Mahmoud F, Reynolds M, Orr LM, Mackintosh SG, Shalin SC, Tackett AJ.

Mol Cell Proteomics. 2016 Mar;15(3):765-75. doi: 10.1074/mcp.M115.053363. Epub 2015 Nov 30.

31.

Identification of Viral and Host Proteins That Interact with Murine Gammaherpesvirus 68 Latency-Associated Nuclear Antigen during Lytic Replication: a Role for Hsc70 in Viral Replication.

Salinas E, Byrum SD, Moreland LE, Mackintosh SG, Tackett AJ, Forrest JC.

J Virol. 2015 Nov 18;90(3):1397-413. doi: 10.1128/JVI.02022-15. Print 2016 Feb 1.

32.

Bioorthogonal labeling cell-surface proteins expressed in pancreatic cancer cells to identify potential diagnostic/therapeutic biomarkers.

Haun RS, Quick CM, Siegel ER, Raju I, Mackintosh SG, Tackett AJ.

Cancer Biol Ther. 2015;16(10):1557-65. doi: 10.1080/15384047.2015.1071740. Epub 2015 Jul 15.

33.

Yeast transcription co-activator Sub1 and its human homolog PC4 preferentially bind to G-quadruplex DNA.

Gao J, Zybailov BL, Byrd AK, Griffin WC, Chib S, Mackintosh SG, Tackett AJ, Raney KD.

Chem Commun (Camb). 2015 Apr 28;51(33):7242-4. doi: 10.1039/c5cc00742a.

34.

CD109 Overexpression in Pancreatic Cancer Identified by Cell-Surface Glycoprotein Capture.

Haun RS, Fan CY, Mackintosh SG, Zhao H, Tackett AJ.

J Proteomics Bioinform. 2014;Suppl 10:S10003.

35.

Glycomic analysis of membrane glycoproteins with bisecting glycosylation from ovarian cancer tissues reveals novel structures and functions.

Allam H, Aoki K, Benigno BB, McDonald JF, Mackintosh SG, Tiemeyer M, Abbott KL.

J Proteome Res. 2015 Jan 2;14(1):434-46. doi: 10.1021/pr501174p. Epub 2014 Dec 9.

36.

A Proteomic Study of Human Merkel Cell Carcinoma.

Shao Q, Byrum SD, Moreland LE, Mackintosh SG, Kannan A, Lin Z, Morgan M, Stack BC Jr, Cornelius LA, Tackett AJ, Gao L.

J Proteomics Bioinform. 2013 Nov 25;6:275-282.

37.

Methylation of histone H3K23 blocks DNA damage in pericentric heterochromatin during meiosis.

Papazyan R, Voronina E, Chapman JR, Luperchio TR, Gilbert TM, Meier E, Mackintosh SG, Shabanowitz J, Tackett AJ, Reddy KL, Coyne RS, Hunt DF, Liu Y, Taverna SD.

Elife. 2014 Aug 26;3:e02996. doi: 10.7554/eLife.02996.

38.

A CRISPR-based approach for proteomic analysis of a single genomic locus.

Waldrip ZJ, Byrum SD, Storey AJ, Gao J, Byrd AK, Mackintosh SG, Wahls WP, Taverna SD, Raney KD, Tackett AJ.

Epigenetics. 2014 Sep;9(9):1207-11. doi: 10.4161/epi.29919. Epub 2014 Jul 18.

39.

The bromodomain of Gcn5 regulates site specificity of lysine acetylation on histone H3.

Cieniewicz AM, Moreland L, Ringel AE, Mackintosh SG, Raman A, Gilbert TM, Wolberger C, Tackett AJ, Taverna SD.

Mol Cell Proteomics. 2014 Nov;13(11):2896-910. doi: 10.1074/mcp.M114.038174. Epub 2014 Aug 8.

40.

Quantitative Proteomics Identifies Activation of Hallmark Pathways of Cancer in Patient Melanoma.

Byrum SD, Larson SK, Avaritt NL, Moreland LE, Mackintosh SG, Cheung WL, Tackett AJ.

J Proteomics Bioinform. 2013 Mar 1;6(3):43-50.

41.

A quantitative proteomic analysis of FFPE melanoma.

Byrum S, Avaritt NL, Mackintosh SG, Munkberg JM, Badgwell BD, Cheung WL, Tackett AJ.

J Cutan Pathol. 2011 Nov;38(11):933-6. doi: 10.1111/j.1600-0560.2011.01761.x. Epub 2011 Aug 23. No abstract available.

42.

Analysis of Histone Exchange during Chromatin Purification.

Byrum S, Mackintosh SG, Edmondson RD, Cheung WL, Taverna SD, Tackett AJ.

J Integr OMICS. 2011 Feb 1;1(1):61-65.

43.

Investigation of translocation, DNA unwinding, and protein displacement by NS3h, the helicase domain from the hepatitis C virus helicase.

Matlock DL, Yeruva L, Byrd AK, Mackintosh SG, Langston C, Brown C, Cameron CE, Fischer CJ, Raney KD.

Biochemistry. 2010 Mar 16;49(10):2097-109. doi: 10.1021/bi901977k.

44.

Mapping the local protein interactome of the NuA3 histone acetyltransferase.

Smart SK, Mackintosh SG, Edmondson RD, Taverna SD, Tackett AJ.

Protein Sci. 2009 Sep;18(9):1987-97. doi: 10.1002/pro.212.

45.

NS3 helicase from the hepatitis C virus can function as a monomer or oligomer depending on enzyme and substrate concentrations.

Jennings TA, Mackintosh SG, Harrison MK, Sikora D, Sikora B, Dave B, Tackett AJ, Cameron CE, Raney KD.

J Biol Chem. 2009 Feb 20;284(8):4806-14. doi: 10.1074/jbc.M805540200. Epub 2008 Dec 16.

46.

DNA unwinding and protein displacement by superfamily 1 and superfamily 2 helicases.

Mackintosh SG, Raney KD.

Nucleic Acids Res. 2006;34(15):4154-9. Epub 2006 Aug 25. Review.

47.

Structural and biological identification of residues on the surface of NS3 helicase required for optimal replication of the hepatitis C virus.

Mackintosh SG, Lu JZ, Jordan JB, Harrison MK, Sikora B, Sharma SD, Cameron CE, Raney KD, Sakon J.

J Biol Chem. 2006 Feb 10;281(6):3528-35. Epub 2005 Nov 22.

48.

Characterization of Staphylococcus aureus SarA binding sites.

Sterba KM, Mackintosh SG, Blevins JS, Hurlburt BK, Smeltzer MS.

J Bacteriol. 2003 Aug;185(15):4410-7.

49.

A single amino acid is critical for the expression of B-cell epitopes on the helicase domain of the pestivirus NS3 protein.

Brown LM, Papa RA, Frost MJ, Mackintosh SG, Gu X, Dixon RJ, Shannon AD.

Virus Res. 2002 Mar 20;84(1-2):111-24.

PMID:
11900844
50.

Mutational analysis of the NH2-terminal arms of the trp repressor indicates a multifunctional domain.

Mackintosh SG, McDermott PF, Hurlburt BK.

Mol Microbiol. 1998 Mar;27(6):1119-27.

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