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Items: 1 to 50 of 68

1.

Antigenic cartography of immune responses to Plasmodium falciparum erythrocyte membrane protein 1 (PfEMP1).

Tuju J, Mackinnon MJ, Abdi AI, Karanja H, Musyoki JN, Warimwe GM, Gitau EN, Marsh K, Bull PC, Urban BC.

PLoS Pathog. 2019 Jul 1;15(7):e1007870. doi: 10.1371/journal.ppat.1007870. eCollection 2019 Jul. Erratum in: PLoS Pathog. 2019 Aug 15;15(8):e1008018.

2.

Adaptation of Plasmodium falciparum to its transmission environment.

Rono MK, Nyonda MA, Simam JJ, Ngoi JM, Mok S, Kortok MM, Abdullah AS, Elfaki MM, Waitumbi JN, El-Hassan IM, Marsh K, Bozdech Z, Mackinnon MJ.

Nat Ecol Evol. 2018 Feb;2(2):377-387. doi: 10.1038/s41559-017-0419-9. Epub 2017 Dec 18.

PMID:
29255304
3.

Environmental Correlation Analysis for Genes Associated with Protection against Malaria.

Mackinnon MJ, Ndila C, Uyoga S, Macharia A, Snow RW, Band G, Rautanen A, Rockett KA, Kwiatkowski DP, Williams TN.

Mol Biol Evol. 2016 May;33(5):1188-204. doi: 10.1093/molbev/msw004. Epub 2016 Jan 6.

4.

New antigens for a multicomponent blood-stage malaria vaccine.

Osier FH, Mackinnon MJ, Crosnier C, Fegan G, Kamuyu G, Wanaguru M, Ogada E, McDade B, Rayner JC, Wright GJ, Marsh K.

Sci Transl Med. 2014 Jul 30;6(247):247ra102. doi: 10.1126/scitranslmed.3008705.

5.

The role of immunity in mosquito-induced attenuation of malaria virulence.

Mackinnon MJ.

Malar J. 2014 Jan 21;13:25. doi: 10.1186/1475-2875-13-25.

6.

Mosquito transmission, growth phenotypes and the virulence of malaria parasites.

Pollitt LC, Mackinnon MJ, Mideo N, Read AF.

Malar J. 2013 Dec 6;12:440. doi: 10.1186/1475-2875-12-440.

7.

Rational deployment of antimalarial drugs in Africa: should first-line combination drugs be reserved for paediatric malaria cases?

Sutherland CJ, Babiker H, Mackinnon MJ, Ranford-Cartwright L, El Sayed BB.

Parasitology. 2011 Oct;138(12):1459-68. doi: 10.1017/S0031182011001144. Epub 2011 Aug 3.

8.

Artemisinin resistance in Plasmodium falciparum is associated with an altered temporal pattern of transcription.

Mok S, Imwong M, Mackinnon MJ, Sim J, Ramadoss R, Yi P, Mayxay M, Chotivanich K, Liong KY, Russell B, Socheat D, Newton PN, Day NP, White NJ, Preiser PR, Nosten F, Dondorp AM, Bozdech Z.

BMC Genomics. 2011 Aug 3;12:391. doi: 10.1186/1471-2164-12-391.

9.

Establishing the extent of malaria transmission and challenges facing pre-elimination in the Republic of Djibouti.

Noor AM, Mohamed MB, Mugyenyi CK, Osman MA, Guessod HH, Kabaria CW, Ahmed IA, Nyonda M, Cook J, Drakeley CJ, Mackinnon MJ, Snow RW.

BMC Infect Dis. 2011 May 11;11:121. doi: 10.1186/1471-2334-11-121.

10.

Review for the generalist: The antinuclear antibody test in children - When to use it and what to do with a positive titer.

Malleson PN, Mackinnon MJ, Sailer-Hoeck M, Spencer CH.

Pediatr Rheumatol Online J. 2010 Oct 20;8:27. doi: 10.1186/1546-0096-8-27.

11.

The selection landscape of malaria parasites.

Mackinnon MJ, Marsh K.

Science. 2010 May 14;328(5980):866-71. doi: 10.1126/science.1185410. Review.

PMID:
20466925
12.

Comparative transcriptional and genomic analysis of Plasmodium falciparum field isolates.

Mackinnon MJ, Li J, Mok S, Kortok MM, Marsh K, Preiser PR, Bozdech Z.

PLoS Pathog. 2009 Oct;5(10):e1000644. doi: 10.1371/journal.ppat.1000644. Epub 2009 Oct 30.

13.

Analysis of immunity to febrile malaria in children that distinguishes immunity from lack of exposure.

Bejon P, Warimwe G, Mackintosh CL, Mackinnon MJ, Kinyanjui SM, Musyoki JN, Bull PC, Marsh K.

Infect Immun. 2009 May;77(5):1917-23. doi: 10.1128/IAI.01358-08. Epub 2009 Feb 17. Erratum in: Infect Immun. 2011 Apr;79(4):1804.

14.

Virulence evolution in response to vaccination: the case of malaria.

Mackinnon MJ, Gandon S, Read AF.

Vaccine. 2008 Jul 18;26 Suppl 3:C42-52. Review.

15.

Breadth and magnitude of antibody responses to multiple Plasmodium falciparum merozoite antigens are associated with protection from clinical malaria.

Osier FH, Fegan G, Polley SD, Murungi L, Verra F, Tetteh KK, Lowe B, Mwangi T, Bull PC, Thomas AW, Cavanagh DR, McBride JS, Lanar DE, Mackinnon MJ, Conway DJ, Marsh K.

Infect Immun. 2008 May;76(5):2240-8. doi: 10.1128/IAI.01585-07. Epub 2008 Mar 3.

16.

Differential antibody responses to Plasmodium falciparum merozoite proteins in Malawian children with severe malaria.

Dobaño C, Rogerson SJ, Mackinnon MJ, Cavanagh DR, Taylor TE, Molyneux ME, McBride JS.

J Infect Dis. 2008 Mar 1;197(5):766-74. doi: 10.1086/527490.

PMID:
18260767
17.

Low multiplication rates of African Plasmodium falciparum isolates and lack of association of multiplication rate and red blood cell selectivity with malaria virulence.

Deans AM, Lyke KE, Thera MA, Plowe CV, Koné A, Doumbo OK, Kai O, Marsh K, Mackinnon MJ, Raza A, Rowe JA.

Am J Trop Med Hyg. 2006 Apr;74(4):554-63.

18.

Drug resistance-virulence relationship in Plasmodium falciparum causing severe malaria in an area of seasonal and unstable transmission.

Giha HA, Elbashir MI, A-Elbasit IE, A-Elgadir TM, ElGhazali GE, Mackinnon MJ, Babiker HA.

Acta Trop. 2006 Feb;97(2):181-7. Epub 2005 Dec 5.

PMID:
16336938
19.

Heritability of malaria in Africa.

Mackinnon MJ, Mwangi TW, Snow RW, Marsh K, Williams TN.

PLoS Med. 2005 Dec;2(12):e340. Epub 2005 Nov 8.

20.

Increased density but not prevalence of gametocytes following drug treatment of Plasmodium falciparum.

Ali E, Mackinnon MJ, Abdel-Muhsin AM, Ahmed S, Walliker D, Babiker HA.

Trans R Soc Trop Med Hyg. 2006 Feb;100(2):176-83. Epub 2005 Oct 27.

PMID:
16257026
21.

Drug resistance models for malaria.

Mackinnon MJ.

Acta Trop. 2005 Jun;94(3):207-17. Review.

PMID:
15894181
22.

Drug resistance in malaria: its population biology and implications for control.

Babiker HA, Mackinnon MJ.

Acta Trop. 2005 Jun;94(3):161-2. Epub 2005 Apr 26. No abstract available.

PMID:
15862285
23.

The effects of mosquito transmission and population bottlenecking on virulence, multiplication rate and rosetting in rodent malaria.

Mackinnon MJ, Bell A, Read AF.

Int J Parasitol. 2005 Feb;35(2):145-53. Epub 2005 Jan 7.

PMID:
15710435
24.

Genetic complexity of Plasmodium falciparum in two ethnic groups of Burkina Faso with marked differences in susceptibility to malaria.

Paganotti GM, Babiker HA, Modiano D, Sirima BS, Verra F, Konaté A, Ouedraogo AL, Diarra A, Mackinnon MJ, Coluzzi M, Walliker D.

Am J Trop Med Hyg. 2004 Aug;71(2):173-8.

PMID:
15306706
25.

Virulence in malaria: an evolutionary viewpoint.

Mackinnon MJ, Read AF.

Philos Trans R Soc Lond B Biol Sci. 2004 Jun 29;359(1446):965-86. Review.

26.

Immunity promotes virulence evolution in a malaria model.

Mackinnon MJ, Read AF.

PLoS Biol. 2004 Sep;2(9):E230. Epub 2004 Jun 22.

27.

Evolution of drug-resistance genes in Plasmodium falciparum in an area of seasonal malaria transmission in Eastern Sudan.

Abdel-Muhsin AM, Mackinnon MJ, Ali E, Nassir el-KA, Suleiman S, Ahmed S, Walliker D, Babiker HA.

J Infect Dis. 2004 Apr 1;189(7):1239-44. Epub 2004 Mar 16.

PMID:
15031793
28.

Mosquito mortality and the evolution of malaria virulence.

Ferguson HM, Mackinnon MJ, Chan BH, Read AF.

Evolution. 2003 Dec;57(12):2792-804.

PMID:
14761058
29.

A human complement receptor 1 polymorphism that reduces Plasmodium falciparum rosetting confers protection against severe malaria.

Cockburn IA, Mackinnon MJ, O'Donnell A, Allen SJ, Moulds JM, Baisor M, Bockarie M, Reeder JC, Rowe JA.

Proc Natl Acad Sci U S A. 2004 Jan 6;101(1):272-7. Epub 2003 Dec 23.

30.

Rodent malaria parasites suffer from the presence of conspecific clones in three-clone Plasmodium chabaudi infections.

De Roode JC, Read AF, Chan BH, Mackinnon MJ.

Parasitology. 2003 Nov;127(Pt 5):411-8.

PMID:
14653530
31.

Virulence in rodent malaria: host genotype by parasite genotype interactions.

Mackinnon MJ, Gaffney DJ, Read AF.

Infect Genet Evol. 2002 Jul;1(4):287-96.

PMID:
12798007
32.

Local differentiation in Plasmodium falciparum drug resistance genes in Sudan.

Abdel-Muhsin AA, Mackinnon MJ, Awadalla P, Ali E, Suleiman S, Ahmed S, Walliker D, Babiker HA.

Parasitology. 2003 May;126(Pt 5):391-400.

PMID:
12793642
33.
34.

Plasmodium chabaudi: rosetting in a rodent malaria model.

Mackinnon MJ, Walker PR, Rowe JA.

Exp Parasitol. 2002 Jun-Jul;101(2-3):121-8. Erratum in: Exp Parasitol. 2002 Oct;102(2):121.

PMID:
12427466
35.

Imperfect vaccines and the evolution of pathogen virulence.

Gandon S, Mackinnon MJ, Nee S, Read AF.

Nature. 2001 Dec 13;414(6865):751-6.

PMID:
11742400
36.

Antimalarial drugs clear resistant parasites from partially immune hosts.

Cravo P, Culleton R, Hunt P, Walliker D, Mackinnon MJ.

Antimicrob Agents Chemother. 2001 Oct;45(10):2897-901.

37.

Novel Plasmodium falciparum clones and rising clone multiplicities are associated with the increase in malaria morbidity in Ghanaian children during the transition into the high transmission season.

Ofosu-Okyere A, Mackinnon MJ, Sowa MP, Koram KA, Nkrumah F, Osei YD, Hill WG, Wilson MD, Arnot DE.

Parasitology. 2001 Aug;123(Pt 2):113-23.

PMID:
11510676
38.

Quantifying genetic and nongenetic contributions to malarial infection in a Sri Lankan population.

Mackinnon MJ, Gunawardena DM, Rajakaruna J, Weerasingha S, Mendis KN, Carter R.

Proc Natl Acad Sci U S A. 2000 Nov 7;97(23):12661-6.

39.

Population dynamics of Plasmodium falciparum in an unstable malaria area of eastern Sudan.

Babiker HA, Abdel-Muhsin AA, Hamad A, Mackinnon MJ, Hill WG, Walliker D.

Parasitology. 2000 Feb;120 ( Pt 2):105-11.

PMID:
10726272
40.

GENETIC RELATIONSHIPS BETWEEN PARASITE VIRULENCE AND TRANSMISSION IN THE RODENT MALARIA PLASMODIUM CHABAUDI.

Mackinnon MJ, Read AF.

Evolution. 1999 Jun;53(3):689-703. doi: 10.1111/j.1558-5646.1999.tb05364.x.

PMID:
28565637
41.

Selection for high and low virulence in the malaria parasite Plasmodium chabaudi.

Mackinnon MJ, Read AF.

Proc Biol Sci. 1999 Apr 7;266(1420):741-8.

42.

The emergence of drug-resistant malaria.

Hastings IM, Mackinnon MJ.

Parasitology. 1998 Nov;117 ( Pt 5):411-7.

PMID:
9836305
43.

The evolution of multiple drug resistance in malaria parasites.

Mackinnon MJ, Hastings IM.

Trans R Soc Trop Med Hyg. 1998 Mar-Apr;92(2):188-95. Review.

PMID:
9764331
44.

VIRULENCE OF MIXED-CLONE AND SINGLE-CLONE INFECTIONS OF THE RODENT MALARIA PLASMODIUM CHABAUDI.

Taylor LH, Mackinnon MJ, Read AF.

Evolution. 1998 Apr;52(2):583-591. doi: 10.1111/j.1558-5646.1998.tb01656.x.

PMID:
28568339
45.

Usefulness of antinuclear antibody testing to screen for rheumatic diseases.

Malleson PN, Sailer M, Mackinnon MJ.

Arch Dis Child. 1997 Oct;77(4):299-304.

46.

Survival probability of drug resistant mutants in malaria parasites.

Mackinnon MJ.

Proc Biol Sci. 1997 Jan 22;264(1378):53-9. Erratum in: Proc R Soc Lond B Biol Sci 1997 Dec 22;264(1389):1849.

47.

Use of deterministic sampling for exploring likelihoods in linkage analysis for quantitative traits.

Mackinnon MJ, van der Beek S, Kinghorn BP.

Theor Appl Genet. 1996 Jan;92(1):130-9. doi: 10.1007/BF00222963.

PMID:
24166128
50.

Autoantibodies in chronic arthritis of childhood: relations with each other and with histocompatibility antigens.

Malleson PN, Fung MY, Petty RE, Mackinnon MJ, Schroeder ML.

Ann Rheum Dis. 1992 Dec;51(12):1301-6.

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