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Items: 9

1.

Towards a better prediction of peak concentration, volume of distribution and half-life after oral drug administration in man, using allometry.

Sinha VK, Vaarties K, De Buck SS, Fenu LA, Nijsen M, Gilissen RA, Sanderson W, Van Uytsel K, Hoeben E, Van Peer A, Mackie CE, Smit JW.

Clin Pharmacokinet. 2011 May;50(5):307-18. doi: 10.2165/11539250-000000000-00000.

PMID:
21456631
2.

Cardio-vascular safety beyond hERG: in silico modelling of a guinea pig right atrium assay.

Fenu LA, Teisman A, De Buck SS, Sinha VK, Gilissen RA, Nijsen MJ, Mackie CE, Sanderson WE.

J Comput Aided Mol Des. 2009 Dec;23(12):883-95. doi: 10.1007/s10822-009-9306-z. Epub 2009 Nov 5.

PMID:
19890608
3.

Predicting oral clearance in humans: how close can we get with allometry?

Sinha VK, De Buck SS, Fenu LA, Smit JW, Nijsen M, Gilissen RA, Van Peer A, Lavrijsen K, Mackie CE.

Clin Pharmacokinet. 2008;47(1):35-45.

PMID:
18076217
4.

Physiologically based approaches towards the prediction of pharmacokinetics: in vitro-in vivo extrapolation.

De Buck SS, Mackie CE.

Expert Opin Drug Metab Toxicol. 2007 Dec;3(6):865-78. Review.

PMID:
18028030
5.

Prediction of human pharmacokinetics using physiologically based modeling: a retrospective analysis of 26 clinically tested drugs.

De Buck SS, Sinha VK, Fenu LA, Nijsen MJ, Mackie CE, Gilissen RA.

Drug Metab Dispos. 2007 Oct;35(10):1766-80. Epub 2007 Jul 9.

PMID:
17620347
6.
7.

Radioimmunoassay for the measurement of S9788 in serum and microdialysis samples.

Mackie CE, English HE, Lelievre E, Gordon BH, GĂ©nissel P, Robinson BV.

J Pharm Biomed Anal. 1997 Apr;15(7):917-28.

PMID:
9160258
8.

The effect of blood transfusion on the incidence of deep vein thrombosis.

Gray DH, Mackie CE.

Aust N Z J Surg. 1983 Oct;53(5):439-43.

PMID:
6579954
9.

The detection of deep venous thrombosis by impedance plethysmography in hip surgery patients.

Gray DH, Mackie CE.

Aust N Z J Surg. 1982 Dec;52(6):569-72.

PMID:
6962725

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