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Items: 1 to 50 of 97

1.

Calcium Alters the Interfacial Organization of Hydrolyzed Lipids during Intestinal Digestion.

Torcello-Gómez A, Boudard C, Mackie AR.

Langmuir. 2018 Jun 26;34(25):7536-7544. doi: 10.1021/acs.langmuir.8b00841. Epub 2018 Jun 14.

PMID:
29870262
2.

Endothelial smoothened-dependent hedgehog signaling is not required for sonic hedgehog induced angiogenesis or ischemic tissue repair.

Gupta R, Mackie AR, Misener S, Liu L, Losordo DW, Kishore R.

Lab Invest. 2018 May;98(5):682-691. doi: 10.1038/s41374-018-0028-5. Epub 2018 Feb 16.

PMID:
29453401
3.

Microcalorimetry of the intestinal mucus: Hydrogen bonding and self-assembly of mucin.

Lousinian S, Mackie AR, Rigby NM, Panayiotou C, Ritzoulis C.

Int J Biol Macromol. 2018 Jun;112:555-560. doi: 10.1016/j.ijbiomac.2018.01.185. Epub 2018 Jan 31.

PMID:
29408005
4.

Can dynamic in vitro digestion systems mimic the physiological reality?

Dupont D, Alric M, Blanquet-Diot S, Bornhorst G, Cueva C, Deglaire A, Denis S, Ferrua M, Havenaar R, Lelieveld J, Mackie AR, Marzorati M, Menard O, Minekus M, Miralles B, Recio I, Van den Abbeele P.

Crit Rev Food Sci Nutr. 2018 Jan 23:1-17. doi: 10.1080/10408398.2017.1421900. [Epub ahead of print]

PMID:
29359955
5.

Downregulation of the Apelinergic Axis Accelerates Aging, whereas Its Systemic Restoration Improves the Mammalian Healthspan.

Rai R, Ghosh AK, Eren M, Mackie AR, Levine DC, Kim SY, Cedernaes J, Ramirez V, Procissi D, Smith LH, Woodruff TK, Bass J, Vaughan DE.

Cell Rep. 2017 Nov 7;21(6):1471-1480. doi: 10.1016/j.celrep.2017.10.057.

6.

Correlation between in vitro and in vivo data on food digestion. What can we predict with static in vitro digestion models?

Bohn T, Carriere F, Day L, Deglaire A, Egger L, Freitas D, Golding M, Le Feunteun S, Macierzanka A, Menard O, Miralles B, Moscovici A, Portmann R, Recio I, Rémond D, Santé-Lhoutelier V, Wooster TJ, Lesmes U, Mackie AR, Dupont D.

Crit Rev Food Sci Nutr. 2017 Jun 14:1-23. doi: 10.1080/10408398.2017.1315362. [Epub ahead of print]

PMID:
28613945
7.

Oatmeal particle size alters glycemic index but not as a function of gastric emptying rate.

Mackie AR, Bajka BH, Rigby NM, Wilde PJ, Alves-Pereira F, Mosleth EF, Rieder A, Kirkhus B, Salt LJ.

Am J Physiol Gastrointest Liver Physiol. 2017 Sep 1;313(3):G239-G246. doi: 10.1152/ajpgi.00005.2017. Epub 2017 Jun 1.

PMID:
28572083
8.

Innovative Methods and Applications in Mucoadhesion Research.

Mackie AR, Goycoolea FM, Menchicchi B, Caramella CM, Saporito F, Lee S, Stephansen K, Chronakis IS, Hiorth M, Adamczak M, Waldner M, Nielsen HM, Marcelloni L.

Macromol Biosci. 2017 Aug;17(8). doi: 10.1002/mabi.201600534. Epub 2017 Apr 5. Review.

PMID:
28378910
9.

Ligand binding to an Allergenic Lipid Transfer Protein Enhances Conformational Flexibility resulting in an Increase in Susceptibility to Gastroduodenal Proteolysis.

Abdullah SU, Alexeev Y, Johnson PE, Rigby NM, Mackie AR, Dhaliwal B, Mills EN.

Sci Rep. 2016 Jul 26;6:30279. doi: 10.1038/srep30279.

10.

Re-evaluation of the mechanisms of dietary fibre and implications for macronutrient bioaccessibility, digestion and postprandial metabolism.

Grundy MM, Edwards CH, Mackie AR, Gidley MJ, Butterworth PJ, Ellis PR.

Br J Nutr. 2016 Sep;116(5):816-33. doi: 10.1017/S0007114516002610. Epub 2016 Jul 7. Review.

11.

Sodium alginate decreases the permeability of intestinal mucus.

Mackie AR, Macierzanka A, Aarak K, Rigby NM, Parker R, Channell GA, Harding SE, Bajka BH.

Food Hydrocoll. 2016 Jan;52:749-755.

12.

Application of recent advances in hydrodynamic methods for characterising mucins in solution.

Almutairi FM, Cifre JG, Adams GG, Kök MS, Mackie AR, de la Torre JG, Harding SE.

Eur Biophys J. 2016 Jan;45(1):45-54. doi: 10.1007/s00249-015-1075-0. Epub 2015 Nov 23.

PMID:
26596272
13.

Enhanced Cardiac Regenerative Ability of Stem Cells After Ischemia-Reperfusion Injury: Role of Human CD34+ Cells Deficient in MicroRNA-377.

Joladarashi D, Garikipati VNS, Thandavarayan RA, Verma SK, Mackie AR, Khan M, Gumpert AM, Bhimaraj A, Youker KA, Uribe C, Suresh Babu S, Jeyabal P, Kishore R, Krishnamurthy P.

J Am Coll Cardiol. 2015 Nov 17;66(20):2214-2226. doi: 10.1016/j.jacc.2015.09.009.

14.

The role of plant cell wall encapsulation and porosity in regulating lipolysis during the digestion of almond seeds.

Grundy MM, Carrière F, Mackie AR, Gray DA, Butterworth PJ, Ellis PR.

Food Funct. 2016 Jan;7(1):69-78. doi: 10.1039/c5fo00758e.

PMID:
26503478
15.

The influence of small intestinal mucus structure on particle transport ex vivo.

Bajka BH, Rigby NM, Cross KL, Macierzanka A, Mackie AR.

Colloids Surf B Biointerfaces. 2015 Nov 1;135:73-80. doi: 10.1016/j.colsurfb.2015.07.038. Epub 2015 Jul 19.

PMID:
26241918
16.

Negative Regulation of miR-375 by Interleukin-10 Enhances Bone Marrow-Derived Progenitor Cell-Mediated Myocardial Repair and Function After Myocardial Infarction.

Garikipati VN, Krishnamurthy P, Verma SK, Khan M, Abramova T, Mackie AR, Qin G, Benedict C, Nickoloff E, Johnson J, Gao E, Losordo DW, Houser SR, Koch WJ, Kishore R.

Stem Cells. 2015 Dec;33(12):3519-29. doi: 10.1002/stem.2121. Epub 2015 Aug 25.

17.

Therapeutic manipulation of angiogenesis with miR-27b.

Veliceasa D, Biyashev D, Qin G, Misener S, Mackie AR, Kishore R, Volpert OV.

Vasc Cell. 2015 Jun 24;7:6. doi: 10.1186/s13221-015-0031-1. eCollection 2015.

18.

Cross-linking of sodium caseinate-structured emulsion with transglutaminase alters postprandial metabolic and appetite responses in healthy young individuals.

Juvonen KR, Macierzanka A, Lille ME, Laaksonen DE, Mykkänen HM, Niskanen LK, Pihlajamäki J, Mäkelä KA, Mills CE, Mackie AR, Malcolm P, Herzig KH, Poutanen KS, Karhunen LJ.

Br J Nutr. 2015 Aug 14;114(3):418-29. doi: 10.1017/S0007114515001737. Epub 2015 Jul 10.

PMID:
26159899
19.

Sirtuin-6 deficiency exacerbates diabetes-induced impairment of wound healing.

Thandavarayan RA, Garikipati VN, Joladarashi D, Suresh Babu S, Jeyabal P, Verma SK, Mackie AR, Khan M, Arumugam S, Watanabe K, Kishore R, Krishnamurthy P.

Exp Dermatol. 2015 Oct;24(10):773-8. doi: 10.1111/exd.12762. Epub 2015 Aug 18.

20.

Embryonic stem cell-derived exosomes promote endogenous repair mechanisms and enhance cardiac function following myocardial infarction.

Khan M, Nickoloff E, Abramova T, Johnson J, Verma SK, Krishnamurthy P, Mackie AR, Vaughan E, Garikipati VN, Benedict C, Ramirez V, Lambers E, Ito A, Gao E, Misener S, Luongo T, Elrod J, Qin G, Houser SR, Koch WJ, Kishore R.

Circ Res. 2015 Jun 19;117(1):52-64. doi: 10.1161/CIRCRESAHA.117.305990. Epub 2015 Apr 22.

21.

Hydrodynamic characterisation of chitosan and its interaction with two polyanions: DNA and xanthan.

Almutairi FM, Erten T, Adams GG, Hayes M, McLoughlin P, Kök MŞ, Mackie AR, Rowe AJ, Harding SE.

Carbohydr Polym. 2015 May 20;122:359-66. doi: 10.1016/j.carbpol.2014.09.090. Epub 2014 Oct 14.

PMID:
25817680
22.

The EuroPrevall outpatient clinic study on food allergy: background and methodology.

Fernández-Rivas M, Barreales L, Mackie AR, Fritsche P, Vázquez-Cortés S, Jedrzejczak-Czechowicz M, Kowalski ML, Clausen M, Gislason D, Sinaniotis A, Kompoti E, Le TM, Knulst AC, Purohit A, de Blay F, Kralimarkova T, Popov T, Asero R, Belohlavkova S, Seneviratne SL, Dubakiene R, Lidholm J, Hoffmann-Sommergruber K, Burney P, Crevel R, Brill M, Fernández-Pérez C, Vieths S, Clare Mills EN, van Ree R, Ballmer-Weber BK.

Allergy. 2015 May;70(5):576-84. doi: 10.1111/all.12585. Epub 2015 Feb 23.

PMID:
25640688
23.

How much is too much? Threshold dose distributions for 5 food allergens.

Ballmer-Weber BK, Fernandez-Rivas M, Beyer K, Defernez M, Sperrin M, Mackie AR, Salt LJ, Hourihane JO, Asero R, Belohlavkova S, Kowalski M, de Blay F, Papadopoulos NG, Clausen M, Knulst AC, Roberts G, Popov T, Sprikkelman AB, Dubakiene R, Vieths S, van Ree R, Crevel R, Mills EN.

J Allergy Clin Immunol. 2015 Apr;135(4):964-71. doi: 10.1016/j.jaci.2014.10.047. Epub 2015 Jan 12.

PMID:
25589011
24.

Transport of particles in intestinal mucus under simulated infant and adult physiological conditions: impact of mucus structure and extracellular DNA.

Macierzanka A, Mackie AR, Bajka BH, Rigby NM, Nau F, Dupont D.

PLoS One. 2014 Apr 22;9(4):e95274. doi: 10.1371/journal.pone.0095274. eCollection 2014.

25.

Specificity of infant digestive conditions: some clues for developing relevant in vitro models.

Bourlieu C, Ménard O, Bouzerzour K, Mandalari G, Macierzanka A, Mackie AR, Dupont D.

Crit Rev Food Sci Nutr. 2014;54(11):1427-57. doi: 10.1080/10408398.2011.640757.

PMID:
24580539
26.

Differential protein kinase C-dependent modulation of Kv7.4 and Kv7.5 subunits of vascular Kv7 channels.

Brueggemann LI, Mackie AR, Cribbs LL, Freda J, Tripathi A, Majetschak M, Byron KL.

J Biol Chem. 2014 Jan 24;289(4):2099-111. doi: 10.1074/jbc.M113.527820. Epub 2013 Dec 2.

27.

A multi-laboratory evaluation of a clinically-validated incurred quality control material for analysis of allergens in food.

Johnson PE, Rigby NM, Dainty JR, Mackie AR, Immer UU, Rogers A, Titchener P, Shoji M, Ryan A, Mata L, Brown H, Holzhauser T, Dumont V, Wykes JA, Walker M, Griffin J, White J, Taylor G, Popping B, Crevel R, Miguel S, Lutter P, Gaskin F, Koerner TB, Clarke D, Sherlock R, Flanagan A, Chan CH, Mills EN.

Food Chem. 2014 Apr 1;148:30-6. doi: 10.1016/j.foodchem.2013.09.115. Epub 2013 Sep 29.

28.

The impact of meal composition on the release of fatty acids from salmon during in vitro gastrointestinal digestion.

Aarak KE, Rigby NM, Kirkhus B, Salt LJ, Sahlstrøm S, Bengtsson GB, Vegarud GE, Mackie AR.

Food Funct. 2013 Dec;4(12):1819-26. doi: 10.1039/c3fo60346f. Epub 2013 Oct 24.

PMID:
24158460
29.

Alcohol consumption negates estrogen-mediated myocardial repair in ovariectomized mice by inhibiting endothelial progenitor cell mobilization and function.

Mackie AR, Krishnamurthy P, Verma SK, Thorne T, Ramirez V, Qin G, Abramova T, Hamada H, Losordo DW, Kishore R.

J Biol Chem. 2013 Jun 21;288(25):18022-34. doi: 10.1074/jbc.M113.468009. Epub 2013 May 3.

30.

Specific food structures supress appetite through reduced gastric emptying rate.

Mackie AR, Rafiee H, Malcolm P, Salt L, van Aken G.

Am J Physiol Gastrointest Liver Physiol. 2013 Jun 1;304(11):G1038-43. doi: 10.1152/ajpgi.00060.2013. Epub 2013 Apr 11.

31.

Bone marrow progenitor cell therapy-mediated paracrine regulation of cardiac miRNA-155 modulates fibrotic response in diabetic hearts.

Kishore R, Verma SK, Mackie AR, Vaughan EE, Abramova TV, Aiko I, Krishnamurthy P.

PLoS One. 2013;8(4):e60161. doi: 10.1371/journal.pone.0060161. Epub 2013 Apr 1.

32.

Stability of sunflower 2S albumins and LTP to physiologically relevant in vitro gastrointestinal digestion.

Berecz B, Clare Mills EN, Parádi I, Láng F, Tamás L, Shewry PR, Mackie AR.

Food Chem. 2013 Jun 15;138(4):2374-81. doi: 10.1016/j.foodchem.2012.12.034. Epub 2012 Dec 31.

PMID:
23497898
33.

The effect of gel structure on the kinetics of simulated gastrointestinal digestion of bovine β-lactoglobulin.

Macierzanka A, Böttger F, Lansonneur L, Groizard R, Jean AS, Rigby NM, Cross K, Wellner N, Mackie AR.

Food Chem. 2012 Oct 15;134(4):2156-63. doi: 10.1016/j.foodchem.2012.04.018. Epub 2012 Apr 13.

PMID:
23442669
34.

Enzymatically structured emulsions in simulated gastrointestinal environment: impact on interfacial proteolysis and diffusion in intestinal mucus.

Macierzanka A, Böttger F, Rigby NM, Lille M, Poutanen K, Mills EN, Mackie AR.

Langmuir. 2012 Dec 18;28(50):17349-62. doi: 10.1021/la302194q. Epub 2012 Dec 4.

PMID:
23171215
35.

Effect of calcium ions on in vitro pellicle formation from parotid and whole saliva.

Ash A, Ridout MJ, Parker R, Mackie AR, Burnett GR, Wilde PJ.

Colloids Surf B Biointerfaces. 2013 Feb 1;102:546-53. doi: 10.1016/j.colsurfb.2012.08.048. Epub 2012 Sep 7.

PMID:
23104024
36.

Lamellar structures of MUC2-rich mucin: a potential role in governing the barrier and lubricating functions of intestinal mucus.

Round AN, Rigby NM, Garcia de la Torre A, Macierzanka A, Mills EN, Mackie AR.

Biomacromolecules. 2012 Oct 8;13(10):3253-61. doi: 10.1021/bm301024x. Epub 2012 Sep 27.

PMID:
22978827
37.

Enhanced angiogenic and cardiomyocyte differentiation capacity of epigenetically reprogrammed mouse and human endothelial progenitor cells augments their efficacy for ischemic myocardial repair.

Thal MA, Krishnamurthy P, Mackie AR, Hoxha E, Lambers E, Verma S, Ramirez V, Qin G, Losordo DW, Kishore R.

Circ Res. 2012 Jul 6;111(2):180-90. doi: 10.1161/CIRCRESAHA.112.270462. Epub 2012 May 15.

38.

Sonic hedgehog-modified human CD34+ cells preserve cardiac function after acute myocardial infarction.

Mackie AR, Klyachko E, Thorne T, Schultz KM, Millay M, Ito A, Kamide CE, Liu T, Gupta R, Sahoo S, Misener S, Kishore R, Losordo DW.

Circ Res. 2012 Jul 20;111(3):312-21. doi: 10.1161/CIRCRESAHA.112.266015. Epub 2012 May 10.

39.

CD34-positive stem cells: in the treatment of heart and vascular disease in human beings.

Mackie AR, Losordo DW.

Tex Heart Inst J. 2011;38(5):474-85. Review.

40.

Development of a standardized low-dose double-blind placebo-controlled challenge vehicle for the EuroPrevall project.

Cochrane SA, Salt LJ, Wantling E, Rogers A, Coutts J, Ballmer-Weber BK, Fritsche P, Fernández-Rivas M, Reig I, Knulst A, Le TM, Asero R, Beyer K, Golding M, Crevel R, Clare Mills EN, Mackie AR.

Allergy. 2012 Jan;67(1):107-13. doi: 10.1111/j.1398-9995.2011.02715.x. Epub 2011 Sep 19.

PMID:
22092081
41.

Boiling peanut Ara h 1 results in the formation of aggregates with reduced allergenicity.

Blanc F, Vissers YM, Adel-Patient K, Rigby NM, Mackie AR, Gunning AP, Wellner NK, Skov PS, Przybylski-Nicaise L, Ballmer-Weber B, Zuidmeer-Jongejan L, Szépfalusi Z, Ruinemans-Koerts J, Jansen AP, Bernard H, Wal JM, Savelkoul HF, Wichers HJ, Mills EN.

Mol Nutr Food Res. 2011 Dec;55(12):1887-94. doi: 10.1002/mnfr.201100251. Epub 2011 Nov 16.

PMID:
22086730
42.

Effect of heating and glycation on the allergenicity of 2S albumins (Ara h 2/6) from peanut.

Vissers YM, Blanc F, Skov PS, Johnson PE, Rigby NM, Przybylski-Nicaise L, Bernard H, Wal JM, Ballmer-Weber B, Zuidmeer-Jongejan L, Szépfalusi Z, Ruinemans-Koerts J, Jansen AP, Savelkoul HF, Wichers HJ, Mackie AR, Mills CE, Adel-Patient K.

PLoS One. 2011;6(8):e23998. doi: 10.1371/journal.pone.0023998. Epub 2011 Aug 25.

43.

Responsiveness of the major birch allergen Bet v 1 scaffold to the gastric environment: impact on structure and allergenic activity.

Sancho AI, Wangorsch A, Jensen BM, Watson A, Alexeev Y, Johnson PE, Mackie AR, Neubauer A, Reese G, Ballmer-Weber B, Hoffmann-Sommergruber K, Skov PS, Vieths S, Mills EN.

Mol Nutr Food Res. 2011 Nov;55(11):1690-9. doi: 10.1002/mnfr.201100025. Epub 2011 Jul 19.

PMID:
21770047
44.

High-pressure treatment reduces the immunoreactivity of the major allergens in apple and celeriac.

Husband FA, Aldick T, Van der Plancken I, Grauwet T, Hendrickx M, Skypala I, Mackie AR.

Mol Nutr Food Res. 2011 Jul;55(7):1087-95. doi: 10.1002/mnfr.201000566. Epub 2011 Apr 26.

PMID:
21520489
45.

Diclofenac distinguishes among homomeric and heteromeric potassium channels composed of KCNQ4 and KCNQ5 subunits.

Brueggemann LI, Mackie AR, Martin JL, Cribbs LL, Byron KL.

Mol Pharmacol. 2011 Jan;79(1):10-23. doi: 10.1124/mol.110.067496. Epub 2010 Sep 28.

47.

High pressure, thermal and pulsed electric-field-induced structural changes in selected food allergens.

Johnson PE, Van der Plancken I, Balasa A, Husband FA, Grauwet T, Hendrickx M, Knorr D, Mills EN, Mackie AR.

Mol Nutr Food Res. 2010 Dec;54(12):1701-10. doi: 10.1002/mnfr.201000006.

PMID:
20568235
48.

Food processing increases casein resistance to simulated infant digestion.

Dupont D, Mandalari G, Mollé D, Jardin J, Rolet-Répécaud O, Duboz G, Léonil J, Mills CE, Mackie AR.

Mol Nutr Food Res. 2010 Nov;54(11):1677-89. doi: 10.1002/mnfr.200900582.

PMID:
20521278
49.

Structural stability and surface activity of sunflower 2S albumins and nonspecific lipid transfer protein.

Berecz B, Mills EN, Tamás L, Láng F, Shewry PR, Mackie AR.

J Agric Food Chem. 2010 May 26;58(10):6490-7. doi: 10.1021/jf100554d.

PMID:
20429585
50.

The structural characteristics of nonspecific lipid transfer proteins explain their resistance to gastroduodenal proteolysis.

Wijesinha-Bettoni R, Alexeev Y, Johnson P, Marsh J, Sancho AI, Abdullah SU, Mackie AR, Shewry PR, Smith LJ, Mills EN.

Biochemistry. 2010 Mar 16;49(10):2130-9. doi: 10.1021/bi901939z.

PMID:
20121231

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