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Items: 1 to 50 of 72

1.

Exploration of long-acting implant formulations of hepatitis B drug entecavir.

Henry SJ, Barrett SE, Forster SP, Teller RS, Yang Z, Li L, Mackey MA, Doto GJ, Ruth MP, Tsuchiya T, Klein LJ, Gindy ME.

Eur J Pharm Sci. 2019 Aug 1;136:104958. doi: 10.1016/j.ejps.2019.104958. Epub 2019 Jun 15.

PMID:
31212018
2.

Extended-Duration MK-8591-Eluting Implant as a Candidate for HIV Treatment and Prevention.

Barrett SE, Teller RS, Forster SP, Li L, Mackey MA, Skomski D, Yang Z, Fillgrove KL, Doto GJ, Wood SL, Lebron J, Grobler JA, Sanchez RI, Liu Z, Lu B, Niu T, Sun L, Gindy ME.

Antimicrob Agents Chemother. 2018 Sep 24;62(10). pii: e01058-18. doi: 10.1128/AAC.01058-18. Print 2018 Oct.

3.

Mixed Reality Meets Pharmaceutical Development.

Forrest WP, Mackey MA, Shah VM, Hassell KM, Shah P, Wylie JL, Gopinath J, Balderhaar H, Li L, Wuelfing WP, Helmy R.

J Pharm Sci. 2017 Dec;106(12):3438-3441. doi: 10.1016/j.xphs.2017.08.020. Epub 2017 Sep 1.

PMID:
28870539
4.

Efficacy, long-term toxicity, and mechanistic studies of gold nanorods photothermal therapy of cancer in xenograft mice.

Ali MR, Rahman MA, Wu Y, Han T, Peng X, Mackey MA, Wang D, Shin HJ, Chen ZG, Xiao H, Wu R, Tang Y, Shin DM, El-Sayed MA.

Proc Natl Acad Sci U S A. 2017 Apr 11;114(15):E3110-E3118. doi: 10.1073/pnas.1619302114. Epub 2017 Mar 29.

5.

In vitro investigations of gold nanocages: Toxicological profile in human keratinocyte cell line.

Saira F, Mackey MA, Qureshi R, Mahmoud MA.

Food Chem Toxicol. 2016 Nov;97:89-95. doi: 10.1016/j.fct.2016.08.014. Epub 2016 Aug 12.

PMID:
27523290
6.

Biological Targeting of Plasmonic Nanoparticles Improves Cellular Imaging via the Enhanced Scattering in the Aggregates Formed.

Aioub M, Kang B, Mackey MA, El-Sayed MA.

J Phys Chem Lett. 2014 Aug 7;5(15):2555-2561. Epub 2014 Jul 5.

7.

The optical, photothermal, and facile surface chemical properties of gold and silver nanoparticles in biodiagnostics, therapy, and drug delivery.

Austin LA, Mackey MA, Dreaden EC, El-Sayed MA.

Arch Toxicol. 2014 Jul;88(7):1391-417. doi: 10.1007/s00204-014-1245-3. Epub 2014 Jun 4. Review.

8.

The most effective gold nanorod size for plasmonic photothermal therapy: theory and in vitro experiments.

Mackey MA, Ali MR, Austin LA, Near RD, El-Sayed MA.

J Phys Chem B. 2014 Feb 6;118(5):1319-26. doi: 10.1021/jp409298f. Epub 2014 Jan 23.

9.

XAV939: from a small inhibitor to a potent drug bioconjugate when delivered by gold nanoparticles.

Afifi MM, Austin LA, Mackey MA, El-Sayed MA.

Bioconjug Chem. 2014 Feb 19;25(2):207-215. doi: 10.1021/bc400271x. Epub 2014 Jan 10.

10.

Antimicrobial activity of water-soluble triazole phenazine clickamers against E. coli.

Hayden SC, Bryant JJ, Mackey MA, Höfer K, Lindner BD, Nguyen VP, Jäschke A, Bunz UH.

Chemistry. 2014 Jan 13;20(3):719-23. doi: 10.1002/chem.201303353. Epub 2013 Dec 11.

PMID:
24339195
11.

Chemosensitization of cancer cells via gold nanoparticle-induced cell cycle regulation.

Mackey MA, El-Sayed MA.

Photochem Photobiol. 2014 Mar-Apr;90(2):306-12. doi: 10.1111/php.12226. Epub 2014 Feb 11.

12.

Surface-enhanced Raman spectroscopy for real-time monitoring of reactive oxygen species-induced DNA damage and its prevention by platinum nanoparticles.

Panikkanvalappil SR, Mahmoud MA, Mackey MA, El-Sayed MA.

ACS Nano. 2013 Sep 24;7(9):7524-33. doi: 10.1021/nn403722x. Epub 2013 Aug 23.

PMID:
23952174
13.

Inducing cancer cell death by targeting its nucleus: solid gold nanospheres versus hollow gold nanocages.

Mackey MA, Saira F, Mahmoud MA, El-Sayed MA.

Bioconjug Chem. 2013 Jun 19;24(6):897-906. doi: 10.1021/bc300592d. Epub 2013 Jun 10. Erratum in: Bioconjug Chem. 2013 Aug 21;24(8):1414.

14.

Probing the unique dehydration-induced structural modifications in cancer cell DNA using surface enhanced Raman spectroscopy.

Panikkanvalappil SR, Mackey MA, El-Sayed MA.

J Am Chem Soc. 2013 Mar 27;135(12):4815-21. doi: 10.1021/ja400187b. Epub 2013 Mar 19.

PMID:
23470053
15.

Selective synthesis, isolation, and crystallographic characterization of LaSc2N@I(h)-C80.

Stevenson S, Rose CB, Maslenikova JS, Villarreal JR, Mackey MA, Mercado BQ, Chen K, Olmstead MM, Balch AL.

Inorg Chem. 2012 Dec 17;51(24):13096-102. doi: 10.1021/ic300888e. Epub 2012 Dec 6.

PMID:
23214426
16.

Induction of mitotic cell death by overriding G2/M checkpoint in endometrial cancer cells with non-functional p53.

Meng X, Laidler LL, Kosmacek EA, Yang S, Xiong Z, Zhu D, Wang X, Dai D, Zhang Y, Wang X, Brachova P, Albitar L, Liu D, Ianzini F, Mackey MA, Leslie KK.

Gynecol Oncol. 2013 Mar;128(3):461-9. doi: 10.1016/j.ygyno.2012.11.004. Epub 2012 Nov 9.

17.

Size matters: gold nanoparticles in targeted cancer drug delivery.

Dreaden EC, Austin LA, Mackey MA, El-Sayed MA.

Ther Deliv. 2012 Apr;3(4):457-78. Review.

18.

Beating cancer in multiple ways using nanogold.

Dreaden EC, Mackey MA, Huang X, Kang B, El-Sayed MA.

Chem Soc Rev. 2011 Jul;40(7):3391-404. doi: 10.1039/c0cs00180e. Epub 2011 May 31. Review.

19.

Remote triggered release of doxorubicin in tumors by synergistic application of thermosensitive liposomes and gold nanorods.

Agarwal A, Mackey MA, El-Sayed MA, Bellamkonda RV.

ACS Nano. 2011 Jun 28;5(6):4919-26. doi: 10.1021/nn201010q. Epub 2011 Jun 2.

PMID:
21591812
20.

The shape of the Sc2(μ2-S) unit trapped in C82: crystallographic, computational, and electrochemical studies of the isomers, Sc2(μ2-S)@C(s)(6)-C82 and Sc2(μ2-S)@C(3v)(8)-C82.

Mercado BQ, Chen N, Rodríguez-Fortea A, Mackey MA, Stevenson S, Echegoyen L, Poblet JM, Olmstead MM, Balch AL.

J Am Chem Soc. 2011 May 4;133(17):6752-60. doi: 10.1021/ja200289w. Epub 2011 Apr 7.

PMID:
21473581
21.

Poly(perfluoroalkylation) of metallic nitride fullerenes reveals addition-pattern guidelines: synthesis and characterization of a family of Sc3N@C80(CF3)n (n = 2-16) and their radical anions.

Shustova NB, Peryshkov DV, Kuvychko IV, Chen YS, Mackey MA, Coumbe CE, Heaps DT, Confait BS, Heine T, Phillips JP, Stevenson S, Dunsch L, Popov AA, Strauss SH, Boltalina OV.

J Am Chem Soc. 2011 Mar 2;133(8):2672-90. doi: 10.1021/ja109462j. Epub 2011 Feb 4.

PMID:
21294511
22.

Comparative study of photothermolysis of cancer cells with nuclear-targeted or cytoplasm-targeted gold nanospheres: continuous wave or pulsed lasers.

Huang X, Kang B, Qian W, Mackey MA, Chen PC, Oyelere AK, El-Sayed IH, El-Sayed MA.

J Biomed Opt. 2010 Sep-Oct;15(5):058002. doi: 10.1117/1.3486538.

PMID:
21054128
23.

Sc2(mu2-O) trapped in a fullerene cage: the isolation and structural characterization of Sc2(mu2-O)@C(s)6-C82 and the relevance of the thermal and entropic effects in fullerene isomer selection.

Mercado BQ, Stuart MA, Mackey MA, Pickens JE, Confait BS, Stevenson S, Easterling ML, Valencia R, Rodríguez-Fortea A, Poblet JM, Olmstead MM, Balch AL.

J Am Chem Soc. 2010 Sep 1;132(34):12098-105. doi: 10.1021/ja104902e.

PMID:
20698534
24.

Redox-tuning endohedral fullerene spin states: from the dication to the trianion radical of Sc(3)N@C(80)(CF(3))(2) in five reversible single-electron steps.

Popov AA, Shustova NB, Svitova AL, Mackey MA, Coumbe CE, Phillips JP, Stevenson S, Strauss SH, Boltalina OV, Dunsch L.

Chemistry. 2010 Apr 26;16(16):4721-4. doi: 10.1002/chem.201000205. No abstract available.

PMID:
20349474
25.

Evidence for singlet-oxygen generation and biocidal activity in photoresponsive metallic nitride fullerene-polymer adhesive films.

McCluskey DM, Smith TN, Madasu PK, Coumbe CE, Mackey MA, Fulmer PA, Wynne JH, Stevenson S, Phillips JP.

ACS Appl Mater Interfaces. 2009 Apr;1(4):882-7. doi: 10.1021/am900008v.

26.

Nuclear targeting of gold nanoparticles in cancer cells induces DNA damage, causing cytokinesis arrest and apoptosis.

Kang B, Mackey MA, El-Sayed MA.

J Am Chem Soc. 2010 Feb 10;132(5):1517-9. doi: 10.1021/ja9102698.

PMID:
20085324
27.

A seven atom cluster in a carbon cage, the crystallographically determined structure of Sc4(mu3-O)3@Ih-C80.

Mercado BQ, Olmstead MM, Beavers CM, Easterling ML, Stevenson S, Mackey MA, Coumbe CE, Phillips JD, Phillips JP, Poblet JM, Balch AL.

Chem Commun (Camb). 2010 Jan 14;46(2):279-81. doi: 10.1039/b918731f. Epub 2009 Nov 9.

PMID:
20024351
28.

Preferential encapsulation and stability of La(3)N cluster in 80 atom cages: experimental synthesis and computational investigation of La(3)N@C(79)N.

Stevenson S, Ling Y, Coumbe CE, Mackey MA, Confait BS, Phillips JP, Dorn HC, Zhang Y.

J Am Chem Soc. 2009 Dec 16;131(49):17780-2. doi: 10.1021/ja908370t.

29.

An open-source deconvolution software package for 3-D quantitative fluorescence microscopy imaging.

Sun Y, Davis P, Kosmacek EA, Ianzini F, Mackey MA.

J Microsc. 2009 Dec;236(3):180-93. doi: 10.1111/j.1365-2818.2009.03205.x.

30.

Selective complexation and reactivity of metallic nitride and oxometallic fullerenes with Lewis acids and use as an effective purification method.

Stevenson S, Mackey MA, Pickens JE, Stuart MA, Confait BS, Phillips JP.

Inorg Chem. 2009 Dec 21;48(24):11685-90. doi: 10.1021/ic9017147.

31.

Sc3N@(C80-Ih7)(CF3)14 and Sc3N@(C80-Ih(7))(CF3)16. Endohedral metallofullerene derivatives with exohedral addends on four and eight triple-hexagon junctions. Does the Sc3N cluster control the addition pattern or vice versa?

Shustova NB, Chen YS, Mackey MA, Coumbe CE, Phillips JP, Stevenson S, Popov AA, Boltalina OV, Strauss SH.

J Am Chem Soc. 2009 Dec 9;131(48):17630-7. doi: 10.1021/ja9069216.

PMID:
19908863
32.

CELL SEGMENTATION USING HESSIAN-BASED DETECTION AND CONTOUR EVOLUTION WITH DIRECTIONAL DERIVATIVES.

Ersoy I, Bunyak F, Mackey MA, Palaniappan K.

Proc Int Conf Image Proc. 2008 Oct 12;2008:1804-1807.

33.

Activation of meiosis-specific genes is associated with depolyploidization of human tumor cells following radiation-induced mitotic catastrophe.

Ianzini F, Kosmacek EA, Nelson ES, Napoli E, Erenpreisa J, Kalejs M, Mackey MA.

Cancer Res. 2009 Mar 15;69(6):2296-304. doi: 10.1158/0008-5472.CAN-08-3364. Epub 2009 Mar 3.

34.

A distorted tetrahedral metal oxide cluster inside an icosahedral carbon cage. Synthesis, isolation, and structural characterization of Sc4(mu3-O)2@Ih-C80.

Stevenson S, Mackey MA, Stuart MA, Phillips JP, Easterling ML, Chancellor CJ, Olmstead MM, Balch AL.

J Am Chem Soc. 2008 Sep 10;130(36):11844-5. doi: 10.1021/ja803679u. Epub 2008 Aug 15.

PMID:
18702488
35.

Effect of copper metal on the yield of Sc3N@C80 metallofullerenes.

Stevenson S, Mackey MA, Thompson MC, Coumbe HL, Madasu PK, Coumbe CE, Phillips JP.

Chem Commun (Camb). 2007 Nov 7;(41):4263-5.

PMID:
18219787
36.

Chemically adjusting plasma temperature, energy, and reactivity (CAPTEAR) method using NOx and combustion for selective synthesis of Sc3N@C80 metallic nitride fullerenes.

Stevenson S, Thompson MC, Coumbe HL, Mackey MA, Coumbe CE, Phillips JP.

J Am Chem Soc. 2007 Dec 26;129(51):16257-62. Epub 2007 Dec 1.

37.

The large-scale digital cell analysis system: an open system for nonperturbing live cell imaging.

Davis PJ, Kosmacek EA, Sun Y, Ianzini F, Mackey MA.

J Microsc. 2007 Dec;228(Pt 3):296-308.

38.

Formal DNA hydrolysis by mono- and dinuclear iron complexes.

Shell TA, Glass JE, Mackey MA, Layman KA, Mohler DL.

Inorg Chem. 2007 Oct 1;46(20):8120-2. Epub 2007 Sep 5.

PMID:
17784754
39.

Radical trifluoromethylation of Sc3N@C80.

Shustova NB, Popov AA, Mackey MA, Coumbe CE, Phillips JP, Stevenson S, Strauss SH, Boltalina OV.

J Am Chem Soc. 2007 Sep 26;129(38):11676-7. Epub 2007 Sep 1. No abstract available.

PMID:
17764184
40.

Human glioblastoma U87MG cells transduced with a dominant negative p53 (TP53) adenovirus construct undergo radiation-induced mitotic catastrophe.

Ianzini F, Domann FE, Kosmacek EA, Phillips SL, Mackey MA.

Radiat Res. 2007 Aug;168(2):183-92.

PMID:
17638400
41.

Rapid removal of D(5)(h) isomer using the "stir and filter approach" and isolation of large quantities of isomerically pure Sc(3)N@C(80) metallic nitride fullerenes.

Stevenson S, Mackey MA, Coumbe CE, Phillips JP, Elliott B, Echegoyen L.

J Am Chem Soc. 2007 May 16;129(19):6072-3. Epub 2007 Apr 26. No abstract available.

PMID:
17458966
42.

Ameboid cell motility: a model and inverse problem, with an application to live cell imaging data.

Coskun H, Li Y, Mackey MA.

J Theor Biol. 2007 Jan 21;244(2):169-79. Epub 2006 Jul 26.

PMID:
16997326
43.

Increase in hybridization rates with oligodeoxyribonucleotides containing locked nucleic acids.

Ormond TK, Spear D, Stoll J, Mackey MA, St John PM.

J Biomol Struct Dyn. 2006 Oct;24(2):171-82.

PMID:
16928140
44.

Cell segmentation, tracking, and mitosis detection using temporal context.

Yang F, Mackey MA, Ianzini F, Gallardo G, Sonka M.

Med Image Comput Comput Assist Interv. 2005;8(Pt 1):302-9.

PMID:
16685859
45.

Lack of p53 function promotes radiation-induced mitotic catastrophe in mouse embryonic fibroblast cells.

Ianzini F, Bertoldo A, Kosmacek EA, Phillips SL, Mackey MA.

Cancer Cell Int. 2006 Apr 26;6:11.

46.

Segregation of genomes in polyploid tumour cells following mitotic catastrophe.

Erenpreisa J, Kalejs M, Ianzini F, Kosmacek EA, Mackey MA, Emzinsh D, Cragg MS, Ivanov A, Illidge TM.

Cell Biol Int. 2005 Dec;29(12):1005-11. Epub 2005 Nov 28.

PMID:
16314119
47.

Mitochondrial O2*- and H2O2 mediate glucose deprivation-induced stress in human cancer cells.

Ahmad IM, Aykin-Burns N, Sim JE, Walsh SA, Higashikubo R, Buettner GR, Venkataraman S, Mackey MA, Flanagan SW, Oberley LW, Spitz DR.

J Biol Chem. 2005 Feb 11;280(6):4254-63. Epub 2004 Nov 23.

48.

The developing world benefits from plant biotechnology.

Mackey MA.

J Nutr Educ Behav. 2003 Jul-Aug;35(4):210-4.

PMID:
12859886
49.

Development of the large scale digital cell analysis system.

Ianzini F, Mackey MA.

Radiat Prot Dosimetry. 2002;99(1-4):289-93.

PMID:
12194309
50.

Mitotic catastrophe induced by exposure of V79 Chinese hamster cells to low-energy protons.

Ianzini F, Cherubini R, Mackey MA.

Int J Radiat Biol. 1999 Jun;75(6):717-23.

PMID:
10405001

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