Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 50 of 138


Mouse Norovirus Infection Arrests Host Cell Translation Uncoupled from the Stress Granule-PKR-eIF2α Axis.

Fritzlar S, Aktepe TE, Chao YW, Kenney ND, McAllaster MR, Wilen CB, White PA, Mackenzie JM.

MBio. 2019 Jun 18;10(3). pii: e00960-19. doi: 10.1128/mBio.00960-19.


Downregulation of MHC Class I Expression by Influenza A and B Viruses.

Koutsakos M, McWilliam HEG, Aktepe TE, Fritzlar S, Illing PT, Mifsud NA, Purcell AW, Rockman S, Reading PC, Vivian JP, Rossjohn J, Brooks AG, Mackenzie JM, Mintern JD, Villadangos JA, Nguyen THO, Kedzierska K.

Front Immunol. 2019 May 29;10:1158. doi: 10.3389/fimmu.2019.01158. eCollection 2019.


The Adenosine Analogue NITD008 has Potent Antiviral Activity against Human and Animal Caliciviruses.

Enosi Tuipulotu D, Fumian TM, Netzler NE, Mackenzie JM, White PA.

Viruses. 2019 May 30;11(6). pii: E496. doi: 10.3390/v11060496.


Nlrp3 inflammasome activation and Gasdermin D-driven pyroptosis are immunopathogenic upon gastrointestinal norovirus infection.

Dubois H, Sorgeloos F, Sarvestani ST, Martens L, Saeys Y, Mackenzie JM, Lamkanfi M, van Loo G, Goodfellow I, Wullaert A.

PLoS Pathog. 2019 Apr 24;15(4):e1007709. doi: 10.1371/journal.ppat.1007709. eCollection 2019 Apr.


Determinants of Zika virus host tropism uncovered by deep mutational scanning.

Setoh YX, Amarilla AA, Peng NYG, Griffiths RE, Carrera J, Freney ME, Nakayama E, Ogawa S, Watterson D, Modhiran N, Nanyonga FE, Torres FJ, Slonchak A, Periasamy P, Prow NA, Tang B, Harrison J, Hobson-Peters J, Cuddihy T, Cooper-White J, Hall RA, Young PR, Mackenzie JM, Wolvetang E, Bloom JD, Suhrbier A, Khromykh AA.

Nat Microbiol. 2019 May;4(5):876-887. doi: 10.1038/s41564-019-0399-4. Epub 2019 Mar 18.


Antiviral Candidates for Treating Hepatitis E Virus Infection.

Netzler NE, Enosi Tuipulotu D, Vasudevan SG, Mackenzie JM, White PA.

Antimicrob Agents Chemother. 2019 May 24;63(6). pii: e00003-19. doi: 10.1128/AAC.00003-19. Print 2019 Jun.


Factors deterring and prompting the decision to attempt suicide on the railway networks: findings from 353 online surveys and 34 semi-structured interviews - ADDENDUM.

Marzano L, Mackenzie JM, Kruger I, Borrill J, Fields B.

Br J Psychiatry. 2019 Mar 14:1. doi: 10.1192/bjp.2019.49. [Epub ahead of print] No abstract available.


Factors deterring and prompting the decision to attempt suicide on the railway networks: findings from 353 online surveys and 34 semi-structured interviews.

Marzano L, Mackenzie JM, Kruger I, Borrill J, Fields B.

Br J Psychiatry. 2019 Feb 6:1-6. doi: 10.1192/bjp.2018.303. [Epub ahead of print]


The Microtubule-Associated Innate Immune Sensor GEF-H1 Does Not Influence Mouse Norovirus Replication in Murine Macrophages.

Fritzlar S, White PA, Mackenzie JM.

Viruses. 2019 Jan 10;11(1). pii: E47. doi: 10.3390/v11010047.


Health inequalities and health equity challenges for victims of modern slavery.

Dando CJ, Brierley R, Saunders K, Mackenzie JM.

J Public Health (Oxf). 2018 Nov 2. doi: 10.1093/pubmed/fdy187. [Epub ahead of print]


Mouse Norovirus Infection Reduces the Surface Expression of Major Histocompatibility Complex Class I Proteins and Inhibits CD8+ T Cell Recognition and Activation.

Fritzlar S, Jegaskanda S, Aktepe TE, Prier JE, Holz LE, White PA, Mackenzie JM.

J Virol. 2018 Aug 29;92(18). pii: e00286-18. doi: 10.1128/JVI.00286-18. Print 2018 Sep 15.


Shaping the flavivirus replication complex: It is curvaceous!

Aktepe TE, Mackenzie JM.

Cell Microbiol. 2018 Aug;20(8):e12884. doi: 10.1111/cmi.12884. Epub 2018 Jun 29. Review.


Accuracy of a history of blood donation from surrogate witnesses: data from the UK TMER study.

Mackenzie JM, Turner M, Morris K, Field S, Molesworth AM, Pal S, Will RG, Llewelyn CA, Hewitt PE.

Vox Sang. 2018 May 15. doi: 10.1111/vox.12661. [Epub ahead of print]


Phospholipase A2 activity during the replication cycle of the flavivirus West Nile virus.

Liebscher S, Ambrose RL, Aktepe TE, Mikulasova A, Prier JE, Gillespie LK, Lopez-Denman AJ, Rupasinghe TWT, Tull D, McConville MJ, Mackenzie JM.

PLoS Pathog. 2018 Apr 30;14(4):e1007029. doi: 10.1371/journal.ppat.1007029. eCollection 2018 Apr.


Behaviours preceding suicides at railway and underground locations: a multimethodological qualitative approach.

Mackenzie JM, Borrill J, Hawkins E, Fields B, Kruger I, Noonan I, Marzano L.

BMJ Open. 2018 Apr 10;8(4):e021076. doi: 10.1136/bmjopen-2017-021076.


Nucleocytoplasmic shuttling of the West Nile virus RNA-dependent RNA polymerase NS5 is critical to infection.

Lopez-Denman AJ, Russo A, Wagstaff KM, White PA, Jans DA, Mackenzie JM.

Cell Microbiol. 2018 Aug;20(8):e12848. doi: 10.1111/cmi.12848. Epub 2018 Apr 24.


TLR7 Agonists Display Potent Antiviral Effects against Norovirus Infection via Innate Stimulation.

Enosi Tuipulotu D, Netzler NE, Lun JH, Mackenzie JM, White PA.

Antimicrob Agents Chemother. 2018 Apr 26;62(5). pii: e02417-17. doi: 10.1128/AAC.02417-17. Print 2018 May.


The Host Protein Reticulon 3.1A Is Utilized by Flaviviruses to Facilitate Membrane Remodelling.

Aktepe TE, Liebscher S, Prier JE, Simmons CP, Mackenzie JM.

Cell Rep. 2017 Nov 7;21(6):1639-1654. doi: 10.1016/j.celrep.2017.10.055.


RNA Sequencing of Murine Norovirus-Infected Cells Reveals Transcriptional Alteration of Genes Important to Viral Recognition and Antigen Presentation.

Enosi Tuipulotu D, Netzler NE, Lun JH, Mackenzie JM, White PA.

Front Immunol. 2017 Aug 11;8:959. doi: 10.3389/fimmu.2017.00959. eCollection 2017.


Broad-spectrum non-nucleoside inhibitors for caliciviruses.

Netzler NE, Enosi Tuipulotu D, Eltahla AA, Lun JH, Ferla S, Brancale A, Urakova N, Frese M, Strive T, Mackenzie JM, White PA.

Antiviral Res. 2017 Oct;146:65-75. doi: 10.1016/j.antiviral.2017.07.014. Epub 2017 Jul 27.


A New Automated Technology for Cerebrospinal Fluid Cell Counts: Comparison of Accuracy and Clinical Impact of GloCyte, Sysmex XN, and Manual Methods.

Sandhaus LM, Dillman CA, Hinkle WP, MacKenzie JM, Hong G.

Am J Clin Pathol. 2017 May 1;147(5):507-514. doi: 10.1093/ajcp/aqx026.


The IMPORTance of the Nucleus during Flavivirus Replication.

Lopez-Denman AJ, Mackenzie JM.

Viruses. 2017 Jan 19;9(1). pii: E14. doi: 10.3390/v9010014. Review.


The Norovirus NS3 Protein Is a Dynamic Lipid- and Microtubule-Associated Protein Involved in Viral RNA Replication.

Cotton BT, Hyde JL, Sarvestani ST, Sosnovtsev SV, Green KY, White PA, Mackenzie JM.

J Virol. 2017 Jan 18;91(3). pii: e02138-16. doi: 10.1128/JVI.02138-16. Print 2017 Feb 1.


Ten-year follow-up of two cohorts with an increased risk of variant CJD: donors to individuals who later developed variant CJD and other recipients of these at-risk donors.

Checchi M, Hewitt PE, Bennett P, Ward HJ, Will RG, Mackenzie JM, Sinka K.

Vox Sang. 2016 Nov;111(4):325-332. doi: 10.1111/vox.12426. Epub 2016 Jul 19.


Norovirus Infection: Replication, Manipulation of Host, and Interaction with the Host Immune Response.

Sarvestani ST, Cotton B, Fritzlar S, O'Donnell TB, Mackenzie JM.

J Interferon Cytokine Res. 2016 Apr;36(4):215-25. doi: 10.1089/jir.2015.0124. Epub 2016 Jan 27. Review.


Mouse Norovirus infection promotes autophagy induction to facilitate replication but prevents final autophagosome maturation.

O'Donnell TB, Hyde JL, Mintern JD, Mackenzie JM.

Virology. 2016 May;492:130-9. doi: 10.1016/j.virol.2016.02.018. Epub 2016 Mar 21.


Creutzfeldt-Jakob disease and blood transfusion: updated results of the UK Transfusion Medicine Epidemiology Review Study.

Urwin PJ, Mackenzie JM, Llewelyn CA, Will RG, Hewitt PE.

Vox Sang. 2016 May;110(4):310-6. doi: 10.1111/vox.12371. Epub 2015 Dec 28.


Axonal Injury in Stroke: A Forensic Neuropathology Perspective.

MacKenzie JM.

Am J Forensic Med Pathol. 2015 Sep;36(3):172-5. doi: 10.1097/PAF.0000000000000166.


Differential utilisation of ceramide during replication of the flaviviruses West Nile and dengue virus.

Aktepe TE, Pham H, Mackenzie JM.

Virology. 2015 Oct;484:241-50. doi: 10.1016/j.virol.2015.06.015. Epub 2015 Jun 26.


Examining the decomposed brain.

MacKenzie JM.

Am J Forensic Med Pathol. 2014 Dec;35(4):265-70. doi: 10.1097/PAF.0000000000000111. Review.


Modulation of hepatitis C virus genome replication by glycosphingolipids and four-phosphate adaptor protein 2.

Khan I, Katikaneni DS, Han Q, Sanchez-Felipe L, Hanada K, Ambrose RL, Mackenzie JM, Konan KV.

J Virol. 2014 Nov;88(21):12276-95. doi: 10.1128/JVI.00970-14. Epub 2014 Aug 13.


Variant CJD and blood transfusion: are there additional cases?

Davidson LR, Llewelyn CA, Mackenzie JM, Hewitt PE, Will RG.

Vox Sang. 2014 Oct;107(3):220-5. doi: 10.1111/vox.12161. Epub 2014 Jun 11.


A nuclear transport inhibitor that modulates the unfolded protein response and provides in vivo protection against lethal dengue virus infection.

Fraser JE, Watanabe S, Wang C, Chan WK, Maher B, Lopez-Denman A, Hick C, Wagstaff KM, Mackenzie JM, Sexton PM, Vasudevan SG, Jans DA.

J Infect Dis. 2014 Dec 1;210(11):1780-91. doi: 10.1093/infdis/jiu319. Epub 2014 Jun 5.


Nonnucleoside inhibitors of norovirus RNA polymerase: scaffolds for rational drug design.

Eltahla AA, Lim KL, Eden JS, Kelly AG, Mackenzie JM, White PA.

Antimicrob Agents Chemother. 2014 Jun;58(6):3115-23. doi: 10.1128/AAC.02799-13. Epub 2014 Mar 17.


Non-structural protein-1 is required for West Nile virus replication complex formation and viral RNA synthesis.

Youn S, Ambrose RL, Mackenzie JM, Diamond MS.

Virol J. 2013 Nov 18;10:339. doi: 10.1186/1743-422X-10-339.


ATF6 signaling is required for efficient West Nile virus replication by promoting cell survival and inhibition of innate immune responses.

Ambrose RL, Mackenzie JM.

J Virol. 2013 Feb;87(4):2206-14. doi: 10.1128/JVI.02097-12. Epub 2012 Dec 5.


Mouse norovirus 1 utilizes the cytoskeleton network to establish localization of the replication complex proximal to the microtubule organizing center.

Hyde JL, Gillespie LK, Mackenzie JM.

J Virol. 2012 Apr;86(8):4110-22. doi: 10.1128/JVI.05784-11. Epub 2012 Feb 1.


A conserved peptide in West Nile virus NS4A protein contributes to proteolytic processing and is essential for replication.

Ambrose RL, Mackenzie JM.

J Virol. 2011 Nov;85(21):11274-82. doi: 10.1128/JVI.05864-11. Epub 2011 Aug 31.


Successful therapy of vitamin D-dependant rickets in a kitten.

MacKenzie JM, Crawford J, Ghantous S.

J Am Anim Hosp Assoc. 2011 Jul-Aug;47(4):290-3. doi: 10.5326/JAAHA-MS-5610. Epub 2011 Jun 14.


West Nile virus differentially modulates the unfolded protein response to facilitate replication and immune evasion.

Ambrose RL, Mackenzie JM.

J Virol. 2011 Mar;85(6):2723-32. doi: 10.1128/JVI.02050-10. Epub 2010 Dec 29.


Comparison of the replication properties of murine and human calicivirus RNA-dependent RNA polymerases.

Bull RA, Hyde J, Mackenzie JM, Hansman GS, Oka T, Takeda N, White PA.

Virus Genes. 2011 Feb;42(1):16-27. doi: 10.1007/s11262-010-0535-y. Epub 2010 Oct 20.


The role of cerebrospinal fluid 14-3-3 and other proteins in the diagnosis of sporadic Creutzfeldt-Jakob disease in the UK: a 10-year review.

Chohan G, Pennington C, Mackenzie JM, Andrews M, Everington D, Will RG, Knight RS, Green AJ.

J Neurol Neurosurg Psychiatry. 2010 Nov;81(11):1243-8. doi: 10.1136/jnnp.2009.197962. Epub 2010 Sep 20.


Isolated Meningeal Recurrence of Transitional Cell Carcinoma of the Bladder.

Butchart C, Dahle-Smith A, Bissett D, Mackenzie JM, Williams DJ.

Case Rep Oncol. 2010 Jun 8;3(2):171-175.


The endoplasmic reticulum provides the membrane platform for biogenesis of the flavivirus replication complex.

Gillespie LK, Hoenen A, Morgan G, Mackenzie JM.

J Virol. 2010 Oct;84(20):10438-47. doi: 10.1128/JVI.00986-10. Epub 2010 Aug 4.


Subcellular localization of the MNV-1 ORF1 proteins and their potential roles in the formation of the MNV-1 replication complex.

Hyde JL, Mackenzie JM.

Virology. 2010 Oct 10;406(1):138-48. doi: 10.1016/j.virol.2010.06.047. Epub 2010 Aug 1.


Validation of diagnostic criteria for variant Creutzfeldt-Jakob disease.

Heath CA, Cooper SA, Murray K, Lowman A, Henry C, MacLeod MA, Stewart GE, Zeidler M, MacKenzie JM, Ironside JW, Summers DM, Knight RS, Will RG.

Ann Neurol. 2010 Jun;67(6):761-70. doi: 10.1002/ana.21987.


Absence of pain with hyperhidrosis: a new syndrome where vascular afferents may mediate cutaneous sensation.

Bowsher D, Geoffrey Woods C, Nicholas AK, Carvalho OM, Haggett CE, Tedman B, Mackenzie JM, Crooks D, Mahmood N, Twomey JA, Hann S, Jones D, Wymer JP, Albrecht PJ, Argoff CE, Rice FL.

Pain. 2009 Dec 15;147(1-3):287-98. doi: 10.1016/j.pain.2009.09.007.


Mouse norovirus replication is associated with virus-induced vesicle clusters originating from membranes derived from the secretory pathway.

Hyde JL, Sosnovtsev SV, Green KY, Wobus C, Virgin HW, Mackenzie JM.

J Virol. 2009 Oct;83(19):9709-19. doi: 10.1128/JVI.00600-09. Epub 2009 Jul 8.


Variant Creutzfeldt-Jakob disease and exposure to fractionated plasma products.

Ward HJ, MacKenzie JM, Llewelyn CA, Knight RS, Hewitt PE, Connor N, Molesworth A, Will RG.

Vox Sang. 2009 Oct;97(3):207-10. doi: 10.1111/j.1423-0410.2009.01205.x. Epub 2009 Jun 16.


Supplemental Content

Loading ...
Support Center