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Computed tomography lung volume estimation to facilitate protective mechanical ventilation in a patient with achondroplasia and spina bifida.

Mackay FC, Roth RG, van Helmond N, Ben-Jacob TK.

Anaesth Intensive Care. 2019 Sep 7:310057X19873003. doi: 10.1177/0310057X19873003. [Epub ahead of print] No abstract available.


The ED-SED Study: A Multicenter, Prospective Cohort Study of Practice Patterns and Clinical Outcomes Associated With Emergency Department SEDation for Mechanically Ventilated Patients.

Fuller BM, Roberts BW, Mohr NM, Knight WA 4th, Adeoye O, Pappal RD, Marshall S, Alunday R, Dettmer M, Goyal M, Gibson C, Levine BJ, Gardner-Gray JM, Mosier J, Dargin J, Mackay F, Johnson NJ, Lokhandwala S, Hough CL, Tonna JE, Tsolinas R, Lin F, Qasim ZA, Harvey CE, Bassin B, Stephens RJ, Yan Y, Carpenter CR, Kollef MH, Avidan MS.

Crit Care Med. 2019 Nov;47(11):1539-1548. doi: 10.1097/CCM.0000000000003928.


Microbiota-Derived Short-Chain Fatty Acids Promote the Memory Potential of Antigen-Activated CD8+ T Cells.

Bachem A, Makhlouf C, Binger KJ, de Souza DP, Tull D, Hochheiser K, Whitney PG, Fernandez-Ruiz D, Dähling S, Kastenmüller W, Jönsson J, Gressier E, Lew AM, Perdomo C, Kupz A, Figgett W, Mackay F, Oleshansky M, Russ BE, Parish IA, Kallies A, McConville MJ, Turner SJ, Gebhardt T, Bedoui S.

Immunity. 2019 Aug 20;51(2):285-297.e5. doi: 10.1016/j.immuni.2019.06.002. Epub 2019 Jul 1.


Analysis of serum B cell-activating factor from the tumor necrosis factor family (BAFF) and its soluble receptors in systemic lupus erythematosus.

Vincent FB, Kandane-Rathnayake R, Koelmeyer R, Hoi AY, Harris J, Mackay F, Morand EF.

Clin Transl Immunology. 2019 Apr 21;8(4):e01047. doi: 10.1002/cti2.1047. eCollection 2019.


Recirculating Intestinal IgA-Producing Cells Regulate Neuroinflammation via IL-10.

Rojas OL, Pröbstel AK, Porfilio EA, Wang AA, Charabati M, Sun T, Lee DSW, Galicia G, Ramaglia V, Ward LA, Leung LYT, Najafi G, Khaleghi K, Garcillán B, Li A, Besla R, Naouar I, Cao EY, Chiaranunt P, Burrows K, Robinson HG, Allanach JR, Yam J, Luck H, Campbell DJ, Allman D, Brooks DG, Tomura M, Baumann R, Zamvil SS, Bar-Or A, Horwitz MS, Winer DA, Mortha A, Mackay F, Prat A, Osborne LC, Robbins C, Baranzini SE, Gommerman JL.

Cell. 2019 Apr 4;177(2):492-493. doi: 10.1016/j.cell.2019.03.037. No abstract available.


Serum soluble Fas and Fas ligand (FasL) in primary Sjögren's syndrome.

Vincent FB, Bubicich M, Downie-Doyle S, Mackay F, Morand EF, Rischmueller M.

Clin Exp Rheumatol. 2019 May-Jun;37 Suppl 118(3):254-256. Epub 2019 Feb 15. No abstract available.


No woman's land? Revisiting border zone denizens.

Mackay F.

J Lesbian Stud. 2019;23(3):397-409. doi: 10.1080/10894160.2019.1565521. Epub 2019 Jan 31.


Recirculating Intestinal IgA-Producing Cells Regulate Neuroinflammation via IL-10.

Rojas OL, Pröbstel AK, Porfilio EA, Wang AA, Charabati M, Sun T, Lee DSW, Galicia G, Ramaglia V, Ward LA, Leung LYT, Najafi G, Khaleghi K, Garcillán B, Li A, Besla R, Naouar I, Cao EY, Chiaranunt P, Burrows K, Robinson HG, Allanach JR, Yam J, Luck H, Campbell DJ, Allman D, Brooks DG, Tomura M, Baumann R, Zamvil SS, Bar-Or A, Horwitz MS, Winer DA, Mortha A, Mackay F, Prat A, Osborne LC, Robbins C, Baranzini SE, Gommerman JL.

Cell. 2019 Jan 24;176(3):610-624.e18. doi: 10.1016/j.cell.2018.11.035. Epub 2019 Jan 3. Erratum in: Cell. 2019 Apr 4;177(2):492-493.


Can You Teach Yourself Point-of-care Ultrasound to a Level of Clinical Competency? Evaluation of a Self-directed Simulation-based Training Program.

Mackay FD, Zhou F, Lewis D, Fraser J, Atkinson PR.

Cureus. 2018 Sep 17;10(9):e3320. doi: 10.7759/cureus.3320.


Analysis of urinary macrophage migration inhibitory factor in systemic lupus erythematosus.

Vincent FB, Slavin L, Hoi AY, Kitching AR, Mackay F, Harris J, Kandane-Rathnayake R, Morand EF.

Lupus Sci Med. 2018 Oct 19;5(1):e000277. doi: 10.1136/lupus-2018-000277. eCollection 2018.


Urinary B-cell-activating factor of the tumour necrosis factor family (BAFF) in systemic lupus erythematosus.

Vincent FB, Kandane-Rathnayake R, Hoi AY, Slavin L, Godsell JD, Kitching AR, Harris J, Nelson CL, Jenkins AJ, Chrysostomou A, Hibbs ML, Kerr PG, Rischmueller M, Mackay F, Morand EF.

Lupus. 2018 Nov;27(13):2029-2040. doi: 10.1177/0961203318804885. Epub 2018 Oct 9.


Methotrexate and BAFF interaction prevents immunization against TNF inhibitors.

Bitoun S, Nocturne G, Ly B, Krzysiek R, Roques P, Pruvost A, Paoletti A, Pascaud J, Dönnes P, Florence K, Gleizes A, Hincelin-Mery A, Allez M, Hacein-Bey-Abina S, Mackay F, Pallardy M, Le Grand R, Mariette X.

Ann Rheum Dis. 2018 Oct;77(10):1463-1470. doi: 10.1136/annrheumdis-2018-213403. Epub 2018 Jun 23.


A loop region of BAFF controls B cell survival and regulates recognition by different inhibitors.

Vigolo M, Chambers MG, Willen L, Chevalley D, Maskos K, Lammens A, Tardivel A, Das D, Kowalczyk-Quintas C, Schuepbach-Mallepell S, Smulski CR, Eslami M, Rolink A, Hummler E, Samy E, Fomekong Nanfack Y, Mackay F, Liao M, Hess H, Jiang X, Schneider P.

Nat Commun. 2018 Mar 23;9(1):1199. doi: 10.1038/s41467-018-03323-8.


Molecular control of B-cell homeostasis in health and malignancy.

Garcillán B, Figgett WA, Infantino S, Lim EX, Mackay F.

Immunol Cell Biol. 2018 May;96(5):453-462. doi: 10.1111/imcb.12030. Epub 2018 Mar 24. Review.


It Just Makes Sense.

Mackay F, Puri N.

Crit Care Med. 2017 Dec;45(12):2111-2112. doi: 10.1097/CCM.0000000000002758. No abstract available.


Arginine methylation catalyzed by PRMT1 is required for B cell activation and differentiation.

Infantino S, Light A, O'Donnell K, Bryant V, Avery DT, Elliott M, Tangye SG, Belz G, Mackay F, Richard S, Tarlinton D.

Nat Commun. 2017 Oct 12;8(1):891. doi: 10.1038/s41467-017-01009-1.


Foxp3+ Tregs are recruited to the retina to repair pathological angiogenesis.

Deliyanti D, Talia DM, Zhu T, Maxwell MJ, Agrotis A, Jerome JR, Hargreaves EM, Gerondakis S, Hibbs ML, Mackay F, Wilkinson-Berka JL.

Nat Commun. 2017 Sep 29;8(1):748. doi: 10.1038/s41467-017-00751-w.


Protective Effect of Inflammasome Activation by Hydrogen Peroxide in a Mouse Model of Septic Shock.

Huet O, Pickering RJ, Tikellis C, Latouche C, Long F, Kingwell B, Dickinson B, Chang CJ, Masters S, Mackay F, Cooper ME, de Haan JB.

Crit Care Med. 2017 Feb;45(2):e184-e194. doi: 10.1097/CCM.0000000000002070.


Antibodies That Block or Activate Mouse B Cell Activating Factor of the Tumor Necrosis Factor (TNF) Family (BAFF), Respectively, Induce B Cell Depletion or B Cell Hyperplasia.

Kowalczyk-Quintas C, Schuepbach-Mallepell S, Vigolo M, Willen L, Tardivel A, Smulski CR, Zheng TS, Gommerman J, Hess H, Gottenberg JE, Mackay F, Donzé O, Schneider P.

J Biol Chem. 2016 Sep 16;291(38):19826-34. doi: 10.1074/jbc.M116.725929. Epub 2016 Jul 22.


NFκB1 is essential to prevent the development of multiorgan autoimmunity by limiting IL-6 production in follicular B cells.

de Valle E, Grigoriadis G, O'Reilly LA, Willis SN, Maxwell MJ, Corcoran LM, Tsantikos E, Cornish JK, Fairfax KA, Vasanthakumar A, Febbraio MA, Hibbs ML, Pellegrini M, Banerjee A, Hodgkin PD, Kallies A, Mackay F, Strasser A, Gerondakis S, Gugasyan R.

J Exp Med. 2016 Apr 4;213(4):621-41. doi: 10.1084/jem.20151182. Epub 2016 Mar 28.


The bigger B cell picture.

Mackay F.

Nat Rev Immunol. 2016 Mar;16(3):133. doi: 10.1038/nri.2016.3. Epub 2016 Jan 25. No abstract available.


Editorial overview: Autoimmunity.

Anderson MS, Mackay F.

Curr Opin Immunol. 2015 Dec;37:v-vii. doi: 10.1016/j.coi.2015.10.004. Epub 2015 Oct 25. Review. No abstract available.


The BAFF receptor TACI controls IL-10 production by regulatory B cells and CLL B cells.

Saulep-Easton D, Vincent FB, Quah PS, Wei A, Ting SB, Croce CM, Tam C, Mackay F.

Leukemia. 2016 Jan;30(1):163-72. doi: 10.1038/leu.2015.174. Epub 2015 Jul 3.


BAFF-driven autoimmunity requires CD19 expression.

Fairfax KA, Tsantikos E, Figgett WA, Vincent FB, Quah PS, LePage M, Hibbs ML, Mackay F.

J Autoimmun. 2015 Aug;62:1-10. doi: 10.1016/j.jaut.2015.06.001. Epub 2015 Jun 20.


Chemokine Signaling Controls Integrity of Radial Glial Scaffold in Developing Spinal Cord and Consequential Proper Position of Boundary Cap Cells.

Zhu Y, Matsumoto T, Nagasawa T, Mackay F, Murakami F.

J Neurosci. 2015 Jun 17;35(24):9211-24. doi: 10.1523/JNEUROSCI.0156-15.2015.


Deleting the BAFF receptor TACI protects against systemic lupus erythematosus without extensive reduction of B cell numbers.

Figgett WA, Deliyanti D, Fairfax KA, Quah PS, Wilkinson-Berka JL, Mackay F.

J Autoimmun. 2015 Jul;61:9-16. doi: 10.1016/j.jaut.2015.04.007. Epub 2015 May 29.


The activin A antagonist follistatin inhibits cystic fibrosis-like lung inflammation and pathology.

Hardy CL, King SJ, Mifsud NA, Hedger MP, Phillips DJ, Mackay F, de Kretser DM, Wilson JW, Rolland JM, O'Hehir RE.

Immunol Cell Biol. 2015 Jul;93(6):567-74. doi: 10.1038/icb.2015.7. Epub 2015 Mar 10.


Efficient conditional gene expression following transplantation of retrovirally transduced bone marrow stem cells.

Chung JY, Mackay F, Alderuccio F.

J Immunol Methods. 2015 Jan;416:183-8. doi: 10.1016/j.jim.2014.11.002. Epub 2014 Nov 8.


IL-10 regulates Aicda expression through miR-155.

Fairfax KA, Gantier MP, Mackay F, Williams BR, McCoy CE.

J Leukoc Biol. 2015 Jan;97(1):71-8. doi: 10.1189/jlb.2A0314-178R. Epub 2014 Nov 7.


Modeling the behavior of confined colloidal particles under shear flow.

Mackay FE, Pastor K, Karttunen M, Denniston C.

Soft Matter. 2014 Nov 21;10(43):8724-30. doi: 10.1039/c4sm01812e.


The tyrosine kinase Lyn limits the cytokine responsiveness of plasma cells to restrict their accumulation in mice.

Infantino S, Jones SA, Walker JA, Maxwell MJ, Light A, O'Donnell K, Tsantikos E, Peperzak V, Phesse T, Ernst M, Mackay F, Hibbs ML, Fairfax KA, Tarlinton DM.

Sci Signal. 2014 Aug 12;7(338):ra77. doi: 10.1126/scisignal.2005105.


Roles of ligands from the TNF superfamily in B cell development, function, and regulation.

Figgett WA, Vincent FB, Saulep-Easton D, Mackay F.

Semin Immunol. 2014 Jun;26(3):191-202. doi: 10.1016/j.smim.2014.06.001. Epub 2014 Jul 2. Review.


Cellular accumulation, lipophilicity and photocytotoxicity of diazido platinum(IV) anticancer complexes.

Pizarro AM, McQuitty RJ, Mackay FS, Zhao Y, Woods JA, Sadler PJ.

ChemMedChem. 2014 Jun;9(6):1169-75. doi: 10.1002/cmdc.201402066. Epub 2014 May 19.


Cytokine-driven loss of plasmacytoid dendritic cell function in chronic lymphocytic leukemia.

Saulep-Easton D, Vincent FB, Le Page M, Wei A, Ting SB, Croce CM, Tam C, Mackay F.

Leukemia. 2014 Oct;28(10):2005-15. doi: 10.1038/leu.2014.105. Epub 2014 Mar 18.


CXCR7 prevents excessive CXCL12-mediated downregulation of CXCR4 in migrating cortical interneurons.

Abe P, Mueller W, Schütz D, MacKay F, Thelen M, Zhang P, Stumm R.

Development. 2014 May;141(9):1857-63. doi: 10.1242/dev.104224. Epub 2014 Apr 9.


The modified medical office assistant role in rural diabetes care.

MacKay FD, Anderson JE, Klein MC, Berkowitz J, MacKay JT, Gailius J.

Can J Rural Med. 2014 Spring;19(2):49-56.


Locally stable diamond colloidal crystal formed in a cholesteric liquid crystal.

Mackay FE, Denniston C.

Soft Matter. 2014 Jul 7;10(25):4430-5. doi: 10.1039/c4sm00046c.


The BAFF/APRIL system in SLE pathogenesis.

Vincent FB, Morand EF, Schneider P, Mackay F.

Nat Rev Rheumatol. 2014 Jun;10(6):365-73. doi: 10.1038/nrrheum.2014.33. Epub 2014 Mar 11. Review.


Gene therapy delivery of myelin oligodendrocyte glycoprotein (MOG) via hematopoietic stem cell transfer induces MOG-specific B cell deletion.

Chung JY, Figgett W, Fairfax K, Bernard C, Chan J, Toh BH, Mackay F, Alderuccio F.

J Immunol. 2014 Mar 15;192(6):2593-601. doi: 10.4049/jimmunol.1203563. Epub 2014 Feb 14.


MHC class II expression in human basophils: induction and lack of functional significance.

Voskamp AL, Prickett SR, Mackay F, Rolland JM, O'Hehir RE.

PLoS One. 2013 Dec 9;8(12):e81777. doi: 10.1371/journal.pone.0081777. eCollection 2013.


CXC chemokine receptor 7 (CXCR7) affects the migration of GnRH neurons by regulating CXCL12 availability.

Memi F, Abe P, Cariboni A, MacKay F, Parnavelas JG, Stumm R.

J Neurosci. 2013 Oct 30;33(44):17527-37. doi: 10.1523/JNEUROSCI.0857-13.2013.


Circulating precursor CCR7(lo)PD-1(hi) CXCR5⁺ CD4⁺ T cells indicate Tfh cell activity and promote antibody responses upon antigen reexposure.

He J, Tsai LM, Leong YA, Hu X, Ma CS, Chevalier N, Sun X, Vandenberg K, Rockman S, Ding Y, Zhu L, Wei W, Wang C, Karnowski A, Belz GT, Ghali JR, Cook MC, Riminton DS, Veillette A, Schwartzberg PL, Mackay F, Brink R, Tangye SG, Vinuesa CG, Mackay CR, Li Z, Yu D.

Immunity. 2013 Oct 17;39(4):770-81. doi: 10.1016/j.immuni.2013.09.007.


The TACI receptor regulates T-cell-independent marginal zone B cell responses through innate activation-induced cell death.

Figgett WA, Fairfax K, Vincent FB, Le Page MA, Katik I, Deliyanti D, Quah PS, Verma P, Grumont R, Gerondakis S, Hertzog P, O'Reilly LA, Strasser A, Mackay F.

Immunity. 2013 Sep 19;39(3):573-83. doi: 10.1016/j.immuni.2013.05.019. Epub 2013 Sep 5.


Clinical associations of serum interleukin-17 in systemic lupus erythematosus.

Vincent FB, Northcott M, Hoi A, Mackay F, Morand EF.

Arthritis Res Ther. 2013 Aug 23;15(4):R97. doi: 10.1186/ar4277.


The BAFF/APRIL system: emerging functions beyond B cell biology and autoimmunity.

Vincent FB, Saulep-Easton D, Figgett WA, Fairfax KA, Mackay F.

Cytokine Growth Factor Rev. 2013 Jun;24(3):203-15. doi: 10.1016/j.cytogfr.2013.04.003. Epub 2013 May 15. Review.


Selective and adaptable access to N,N'-asymmetrically substituted imidazol-2-ylidene bis-NHC ligands: Pd(II) complexes featuring wide variation in N-alkyl and aryl steric bulk.

Gardiner MG, Ho CC, Mackay FM, McGuinness DS, Tucker M.

Dalton Trans. 2013 May 28;42(20):7447-57. doi: 10.1039/c3dt32895c.


Mcl-1 is essential for the survival of plasma cells.

Peperzak V, Vikström I, Walker J, Glaser SP, LePage M, Coquery CM, Erickson LD, Fairfax K, Mackay F, Strasser A, Nutt SL, Tarlinton DM.

Nat Immunol. 2013 Mar;14(3):290-7. doi: 10.1038/ni.2527. Epub 2013 Feb 3. Erratum in: Nat Immunol. 2013 Aug;14(8):877.


B cell survival, surface BCR and BAFFR expression, CD74 metabolism, and CD8- dendritic cells require the intramembrane endopeptidase SPPL2A.

Bergmann H, Yabas M, Short A, Miosge L, Barthel N, Teh CE, Roots CM, Bull KR, Jeelall Y, Horikawa K, Whittle B, Balakishnan B, Sjollema G, Bertram EM, Mackay F, Rimmer AJ, Cornall RJ, Field MA, Andrews TD, Goodnow CC, Enders A.

J Exp Med. 2013 Jan 14;210(1):31-40. doi: 10.1084/jem.20121076. Epub 2012 Dec 24.


Antidrug antibodies (ADAb) to tumour necrosis factor (TNF)-specific neutralising agents in chronic inflammatory diseases: a real issue, a clinical perspective.

Vincent FB, Morand EF, Murphy K, Mackay F, Mariette X, Marcelli C.

Ann Rheum Dis. 2013 Feb;72(2):165-78. doi: 10.1136/annrheumdis-2012-202545. Epub 2012 Nov 24. Review.


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