Format

Send to

Choose Destination
Exp Parasitol. 2016 Jun;165:64-70. doi: 10.1016/j.exppara.2016.03.017. Epub 2016 Mar 16.

Composition and biological activities of the essential oil of Piper corcovadensis (Miq.) C. DC (Piperaceae).

Author information

1
Departamento de Química Fundamental, Universidade Federal de Pernambuco, 50740-560, Recife, PE, Brazil.
2
Departamento de Bioquímica, Universidade Federal de Pernambuco, 50670-420, Recife, PE, Brazil; Jardim Botânico de Recife, Pernambuco, 54240-450, Recife, PE, Brazil.
3
Departamento de Morfologia e Fisiologia Animal, Universidade Federal Rural de Pernambuco, 52171-900, Recife, PE, Brazil.
4
Jardim Botânico de Recife, Pernambuco, 54240-450, Recife, PE, Brazil.
5
Departamento de Bioquímica, Universidade Federal de Pernambuco, 50670-420, Recife, PE, Brazil.
6
Departamento de Química Fundamental, Universidade Federal de Pernambuco, 50740-560, Recife, PE, Brazil. Electronic address: dmafn@ufpe.br.

Abstract

Essential oil from fresh leaves of the shrub Piper corcovadensis (Miq.) C. DC was obtained in 0.21% (w/w) yield by hydrodistillation in a Clevenger type apparatus. Thirty-one components, accounting for 96.61% of the leaf oil, were identified by gas chromatography-mass spectrometry. The major constituents of the oil were 1-butyl-3,4-methylenedioxybenzene (30.62%), terpinolene (17.44%), trans -caryophyllene (6.27%), α-pinene (5.92%), δ-cadinene (4.92%), and Limonene (4.46%). Bioassays against larvae of the Dengue mosquito (Aedes aegypti) revealed that leaf oil (LC50 = 30.52 ppm), terpinolene (LC50 = 31.16 ppm), and pure 1-butyl-3,4-methylenedioxybenzene (LC50 = 22.1 ppm) possessed larvicidal activities and are able to interfere with the activity of proteases from L4 gut enzymes. Additionally, the essential oil exhibited a strong oviposition deterrent activity at 50 and 5 ppm. This paper constitutes the first report of biological activities associated with the essential oil of leaves of P. corcovadensis.

KEYWORDS:

1-Butyl-3,4-methylenedioxybenzene; Essential oil; Larvicidal activity; Oviposition activity; Piper corcovadensis; Piperaceae; Proteases enzymes

PMID:
26993082
DOI:
10.1016/j.exppara.2016.03.017
[Indexed for MEDLINE]

Supplemental Content

Full text links

Icon for Elsevier Science
Loading ...
Support Center