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Items: 1 to 50 of 55

1.

Positive impact of low-dose, high-energy radiation on bone in partial- and/or full-weightbearing mice.

Bokhari RS, Metzger CE, Black JM, Franklin KA, Boudreaux RD, Allen MR, Macias BR, Hogan HA, Braby LA, Bloomfield SA.

NPJ Microgravity. 2019 Jun 4;5:13. doi: 10.1038/s41526-019-0074-3. eCollection 2019.

PMID:
31231675
2.

Gravitational Influence on Intraocular Pressure Implications for Spaceflight and Disease.

Huang AS, Stenger MB, Macias BR.

J Glaucoma. 2019 May 31. doi: 10.1097/IJG.0000000000001293. [Epub ahead of print]

PMID:
31162175
3.

The NASA Twins Study: A multidimensional analysis of a year-long human spaceflight.

Garrett-Bakelman FE, Darshi M, Green SJ, Gur RC, Lin L, Macias BR, McKenna MJ, Meydan C, Mishra T, Nasrini J, Piening BD, Rizzardi LF, Sharma K, Siamwala JH, Taylor L, Vitaterna MH, Afkarian M, Afshinnekoo E, Ahadi S, Ambati A, Arya M, Bezdan D, Callahan CM, Chen S, Choi AMK, Chlipala GE, Contrepois K, Covington M, Crucian BE, De Vivo I, Dinges DF, Ebert DJ, Feinberg JI, Gandara JA, George KA, Goutsias J, Grills GS, Hargens AR, Heer M, Hillary RP, Hoofnagle AN, Hook VYH, Jenkinson G, Jiang P, Keshavarzian A, Laurie SS, Lee-McMullen B, Lumpkins SB, MacKay M, Maienschein-Cline MG, Melnick AM, Moore TM, Nakahira K, Patel HH, Pietrzyk R, Rao V, Saito R, Salins DN, Schilling JM, Sears DD, Sheridan CK, Stenger MB, Tryggvadottir R, Urban AE, Vaisar T, Van Espen B, Zhang J, Ziegler MG, Zwart SR, Charles JB, Kundrot CE, Scott GBI, Bailey SM, Basner M, Feinberg AP, Lee SMC, Mason CE, Mignot E, Rana BK, Smith SM, Snyder MP, Turek FW.

Science. 2019 Apr 12;364(6436). pii: eaau8650. doi: 10.1126/science.aau8650.

PMID:
30975860
4.

Optic Disc Edema after 30 Days of Strict Head-down Tilt Bed Rest.

Laurie SS, Macias BR, Dunn JT, Young M, Stern C, Lee SMC, Stenger MB.

Ophthalmology. 2019 Mar;126(3):467-468. doi: 10.1016/j.ophtha.2018.09.042. Epub 2018 Oct 9. No abstract available.

PMID:
30308219
5.

Tibia Bone Microvascular Flow Dynamics as Compared to Anterior Tibial Artery Flow During Body Tilt.

Becker RL, Siamwala JH, Macias BR, Hargens AR.

Aerosp Med Hum Perform. 2018 Apr 1;89(4):357-364. doi: 10.3357/AMHP.4928.2018.

PMID:
29562965
6.

Thigh Cuffs as a Countermeasure for Ocular Changes in Simulated Weightlessness.

Balasubramanian S, Tepelus T, Stenger MB, Lee SMC, Laurie SS, Liu JHK, Feiveson AH, Sadda SR, Huang AS, Macias BR.

Ophthalmology. 2018 Mar;125(3):459-460. doi: 10.1016/j.ophtha.2017.10.023. Epub 2017 Nov 16. No abstract available.

PMID:
29153458
7.

Thirty days of spaceflight does not alter murine calvariae structure despite increased Sost expression.

Macaulay TR, Siamwala JH, Hargens AR, Macias BR.

Bone Rep. 2017 Aug 18;7:57-62. doi: 10.1016/j.bonr.2017.08.004. eCollection 2017 Dec.

8.

Muscle Microvascular Blood Flow, Oxygenation, pH, and Perfusion Pressure Decrease in Simulated Acute Compartment Syndrome.

Challa ST, Hargens AR, Uzosike A, Macias BR.

J Bone Joint Surg Am. 2017 Sep 6;99(17):1453-1459. doi: 10.2106/JBJS.16.01191.

9.

Treadmill exercise within lower-body negative pressure attenuates simulated spaceflight-induced reductions of balance abilities in men but not women.

Macaulay TR, Macias BR, Lee SM, Boda WL, Watenpaugh DE, Hargens AR.

NPJ Microgravity. 2016 Jun 30;2:16022. doi: 10.1038/npjmgrav.2016.22. eCollection 2016.

10.

Lower-body negative pressure decreases noninvasively measured intracranial pressure and internal jugular vein cross-sectional area during head-down tilt.

Watkins W, Hargens AR, Seidl S, Clary EM, Macias BR.

J Appl Physiol (1985). 2017 Jul 1;123(1):260-266. doi: 10.1152/japplphysiol.00091.2017. Epub 2017 May 11.

11.

Gender differences in tibial microvascular flow responses to head down tilt and lower body negative pressure.

Siamwala JH, Macias BR, Lee PC, Hargens AR.

Physiol Rep. 2017 Feb;5(4). pii: e13143. doi: 10.14814/phy2.13143. Epub 2017 Feb 27.

12.

Lumbar Spine Paraspinal Muscle and Intervertebral Disc Height Changes in Astronauts After Long-Duration Spaceflight on the International Space Station.

Chang DG, Healey RM, Snyder AJ, Sayson JV, Macias BR, Coughlin DG, Bailey JF, Parazynski SE, Lotz JC, Hargens AR.

Spine (Phila Pa 1976). 2016 Dec 15;41(24):1917-1924.

13.

Simulating the Lunar Environment: Partial Weightbearing and High-LET Radiation-Induce Bone Loss and Increase Sclerostin-Positive Osteocytes.

Macias BR, Lima F, Swift JM, Shirazi-Fard Y, Greene ES, Allen MR, Fluckey J, Hogan HA, Braby L, Wang S, Bloomfield SA.

Radiat Res. 2016 Sep;186(3):254-63. doi: 10.1667/RR13579.1. Epub 2016 Aug 18.

PMID:
27538114
14.

Treadmill exercise within lower body negative pressure protects leg lean tissue mass and extensor strength and endurance during bed rest.

Schneider SM, Lee SM, Feiveson AH, Watenpaugh DE, Macias BR, Hargens AR.

Physiol Rep. 2016 Aug;4(15). pii: e12892. doi: 10.14814/phy2.12892.

15.

WISE 2005: Aerobic and resistive countermeasures prevent paraspinal muscle deconditioning during 60-day bed rest in women.

Holt JA, Macias BR, Schneider SM, Watenpaugh DE, Lee SM, Chang DG, Hargens AR.

J Appl Physiol (1985). 2016 May 15;120(10):1215-22. doi: 10.1152/japplphysiol.00532.2015. Epub 2016 Feb 18.

16.

Spaceflight-induced bone loss alters failure mode and reduces bending strength in murine spinal segments.

Berg-Johansen B, Liebenberg EC, Li A, Macias BR, Hargens AR, Lotz JC.

J Orthop Res. 2016 Jan;34(1):48-57. doi: 10.1002/jor.23029. Epub 2015 Aug 31.

17.

Shoulder skin and muscle hemodynamics during backpack carriage.

Mao CP, Macias BR, Hargens AR.

Appl Ergon. 2015 Nov;51:80-4. doi: 10.1016/j.apergo.2015.04.006. Epub 2015 May 19.

PMID:
26154207
18.

Lower-body negative pressure restores leg bone microvascular flow to supine levels during head-down tilt.

Siamwala JH, Lee PC, Macias BR, Hargens AR.

J Appl Physiol (1985). 2015 Jul 15;119(2):101-9. doi: 10.1152/japplphysiol.00028.2015. Epub 2015 Apr 30.

19.

Intraocular and intracranial pressures during head-down tilt with lower body negative pressure.

Macias BR, Liu JH, Grande-Gutierrez N, Hargens AR.

Aerosp Med Hum Perform. 2015 Jan;86(1):3-7. doi: 10.3357/AMHP.4044.2015.

PMID:
25565526
20.

Sex-specific responses of bone metabolism and renal stone risk during bed rest.

Morgan JL, Heer M, Hargens AR, Macias BR, Hudson EK, Shackelford LC, Zwart SR, Smith SM.

Physiol Rep. 2014 Aug 7;2(8). pii: e12119. doi: 10.14814/phy2.12119. Print 2014 Aug 1.

21.

Low dose PTH improves metaphyseal bone healing more when muscles are paralyzed.

Sandberg O, Macias BR, Aspenberg P.

Bone. 2014 Jun;63:15-9. doi: 10.1016/j.bone.2014.02.008. Epub 2014 Feb 26.

22.

WISE-2005: Countermeasures to prevent muscle deconditioning during bed rest in women.

Lee SM, Schneider SM, Feiveson AH, Macias BR, Smith SM, Watenpaugh DE, Hargens AR.

J Appl Physiol (1985). 2014 Mar 15;116(6):654-67. doi: 10.1152/japplphysiol.00590.2013. Epub 2014 Jan 23.

23.

Upper extremity hemodynamics and sensation with backpack loads.

Kim SH, Neuschwander TB, Macias BR, Bachman L Jr, Hargens AR.

Appl Ergon. 2014 May;45(3):608-12. doi: 10.1016/j.apergo.2013.08.005. Epub 2013 Sep 26.

PMID:
24075289
24.

Partial weight bearing does not prevent musculoskeletal losses associated with disuse.

Swift JM, Lima F, Macias BR, Allen MR, Greene ES, Shirazi-Fard Y, Kupke JS, Hogan HA, Bloomfield SA.

Med Sci Sports Exerc. 2013 Nov;45(11):2052-60. doi: 10.1249/MSS.0b013e318299c614.

PMID:
23657172
25.

Paradoxical Sost gene expression response to mechanical unloading in metaphyseal bone.

Macias BR, Aspenberg P, Agholme F.

Bone. 2013 Apr;53(2):515-9. doi: 10.1016/j.bone.2013.01.018. Epub 2013 Jan 19.

PMID:
23337040
26.

Leg intramuscular pressures and in vivo knee forces during lower body positive and negative pressure treadmill exercise.

Macias BR, D'Lima DD, Cutuk A, Patil S, Steklov N, Neuschwander TB, Meuche S, Colwell CW, Hargens AR.

J Appl Physiol (1985). 2012 Jul;113(1):31-8. doi: 10.1152/japplphysiol.01434.2011. Epub 2012 Apr 26.

27.

Simulated resistance training, but not alendronate, increases cortical bone formation and suppresses sclerostin during disuse.

Macias BR, Swift JM, Nilsson MI, Hogan HA, Bouse SD, Bloomfield SA.

J Appl Physiol (1985). 2012 Mar;112(5):918-25. doi: 10.1152/japplphysiol.00978.2011. Epub 2011 Dec 15.

28.

Insulin resistance syndrome blunts the mitochondrial anabolic response following resistance exercise.

Nilsson MI, Greene NP, Dobson JP, Wiggs MP, Gasier HG, Macias BR, Shimkus KL, Fluckey JD.

Am J Physiol Endocrinol Metab. 2010 Sep;299(3):E466-74. doi: 10.1152/ajpendo.00118.2010. Epub 2010 Jul 6.

29.

The effect of backpacks on the lumbar spine in children: a standing magnetic resonance imaging study.

Neuschwander TB, Cutrone J, Macias BR, Cutrone S, Murthy G, Chambers H, Hargens AR.

Spine (Phila Pa 1976). 2010 Jan 1;35(1):83-8. doi: 10.1097/BRS.0b013e3181b21a5d.

PMID:
20023607
30.

WISE-2005: exercise and nutrition countermeasures for upright VO2pk during bed rest.

Schneider SM, Lee SM, Macias BR, Watenpaugh DE, Hargens AR.

Med Sci Sports Exerc. 2009 Dec;41(12):2165-76. doi: 10.1249/MSS.0b013e3181aa04e5.

PMID:
19915502
31.

New noninvasive ultrasound technique for monitoring perfusion pressure in a porcine model of acute compartment syndrome.

Garabekyan T, Murphey GC, Macias BR, Lynch JE, Hargens AR.

J Orthop Trauma. 2009 Mar;23(3):186-93; discussion 193-4. doi: 10.1097/BOT.0b013e31819901db.

32.

WISE-2005: effect of aerobic and resistive exercises on orthostatic tolerance during 60 days bed rest in women.

Guinet P, Schneider SM, Macias BR, Watenpaugh DE, Hughson RL, Le Traon AP, Bansard JY, Hargens AR.

Eur J Appl Physiol. 2009 May;106(2):217-27. doi: 10.1007/s00421-009-1009-6. Epub 2009 Feb 27.

33.

Depth of penetration of negative pressure wound therapy into underlying tissues.

Murphey GC, Macias BR, Hargens AR.

Wound Repair Regen. 2009 Jan-Feb;17(1):113-7. doi: 10.1111/j.1524-475X.2008.00448.x.

PMID:
19152658
34.

LBNP exercise protects aerobic capacity and sprint speed of female twins during 30 days of bed rest.

Lee SM, Schneider SM, Boda WL, Watenpaugh DE, Macias BR, Meyer RS, Hargens AR.

J Appl Physiol (1985). 2009 Mar;106(3):919-28. doi: 10.1152/japplphysiol.91502.2008. Epub 2008 Dec 26.

35.

Intramuscular pressures in antigravity muscles using gravity-independent, pneumatic hardware.

Macias BR, Minocha R, Cutuk AA, Hill J, Shiau J, Hargens AR.

Aviat Space Environ Med. 2008 Aug;79(8):749-53.

PMID:
18717112
36.

Heritability of bone density: regional and gender differences in monozygotic twins.

Tse KY, Macias BR, Meyer RS, Hargens AR.

J Orthop Res. 2009 Feb;27(2):150-4. doi: 10.1002/jor.20721.

37.

Asymmetric loads and pain associated with backpack carrying by children.

Macias BR, Murthy G, Chambers H, Hargens AR.

J Pediatr Orthop. 2008 Jul-Aug;28(5):512-7. doi: 10.1097/BPO.0b013e31817d8143.

PMID:
18580364
38.

Inelastic compression legging produces gradient compression and significantly higher skin surface pressures compared with an elastic compression stocking.

Kline CN, Macias BR, Kraus E, Neuschwander TB, Angle N, Bergan J, Hargens AR.

Vascular. 2008 Jan-Feb;16(1):25-30.

PMID:
18258159
39.

WISE-2005: supine treadmill exercise within lower body negative pressure and flywheel resistive exercise as a countermeasure to bed rest-induced bone loss in women during 60-day simulated microgravity.

Smith SM, Zwart SR, Heer M, Lee SM, Baecker N, Meuche S, Macias BR, Shackelford LC, Schneider S, Hargens AR.

Bone. 2008 Mar;42(3):572-81. doi: 10.1016/j.bone.2007.11.015. Epub 2007 Dec 14.

PMID:
18249055
40.

Lower body negative pressure exercise plus brief postexercise lower body negative pressure improve post-bed rest orthostatic tolerance.

Watenpaugh DE, O'Leary DD, Schneider SM, Lee SM, Macias BR, Tanaka K, Hughson RL, Hargens AR.

J Appl Physiol (1985). 2007 Dec;103(6):1964-72. Epub 2007 Oct 18.

41.

The effect of kneeling during spine surgery on leg intramuscular pressure.

Leek BT, Meyer RS, Wiemann JM, Cutuk A, Macias BR, Hargens AR.

J Bone Joint Surg Am. 2007 Sep;89(9):1941-7.

PMID:
17768190
42.

Supine LBNP exercise maintains exercise capacity in male twins during 30-d bed rest.

Lee SM, Schneider SM, Boda WL, Watenpaugh DE, Macias BR, Meyer RS, Hargens AR.

Med Sci Sports Exerc. 2007 Aug;39(8):1315-26.

PMID:
17762365
43.

LBNP treadmill exercise maintains spine function and muscle strength in identical twins during 28-day simulated microgravity.

Macias BR, Cao P, Watenpaugh DE, Hargens AR.

J Appl Physiol (1985). 2007 Jun;102(6):2274-8. Epub 2007 Mar 29.

44.

Cardiac atrophy in women following bed rest.

Dorfman TA, Levine BD, Tillery T, Peshock RM, Hastings JL, Schneider SM, Macias BR, Biolo G, Hargens AR.

J Appl Physiol (1985). 2007 Jul;103(1):8-16. Epub 2007 Mar 22.

45.

Lower body negative pressure treadmill exercise is more comfortable and produces similar physiological responses as weighted vest exercise.

Macias BR, Groppo ER, Bawa M, Tran Cao HS, Lee B, Pedowitz RA, Hargens AR.

Int J Sports Med. 2007 Jun;28(6):501-5. Epub 2006 Nov 16.

PMID:
17111308
46.

Lower body negative pressure treadmill exercise as a countermeasure for bed rest-induced bone loss in female identical twins.

Zwart SR, Hargens AR, Lee SM, Macias BR, Watenpaugh DE, Tse K, Smith SM.

Bone. 2007 Feb;40(2):529-37. Epub 2006 Oct 27.

47.

Heterogeneity of responses to orthostatic stress in homozygous twins.

O'Leary DD, Hughson RL, Shoemaker JK, Greaves DK, Watenpaugh DE, Macias BR, Hargens AR.

J Appl Physiol (1985). 2007 Jan;102(1):249-54. Epub 2006 Sep 28.

48.

High contact pressure beneath backpack straps of children contributes to pain.

Macias BR, Murthy G, Chambers H, Hargens AR.

Arch Pediatr Adolesc Med. 2005 Dec;159(12):1186-7. No abstract available.

PMID:
16330746
49.

Noninvasive assessment of intracranial pressure waveforms by using pulsed phase lock loop technology. Technical note.

Ueno T, Macias BR, Yost WT, Hargens AR.

J Neurosurg. 2005 Aug;103(2):361-7.

PMID:
16175869
50.

Space exercise and Earth benefits.

Macias BR, Groppo ER, Eastlack RK, Watenpaugh DE, Lee SM, Schneider SM, Boda WL, Smith SM, Cutuk A, Pedowitz RA, Meyer RS, Hargens AR.

Curr Pharm Biotechnol. 2005 Aug;6(4):305-17. Review.

PMID:
16101469

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