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Items: 21


ALPK1- and TIFA-Dependent Innate Immune Response Triggered by the Helicobacter pylori Type IV Secretion System.

Zimmermann S, Pfannkuch L, Al-Zeer MA, Bartfeld S, Koch M, Liu J, Rechner C, Soerensen M, Sokolova O, Zamyatina A, Kosma P, Mäurer AP, Glowinski F, Pleissner KP, Schmid M, Brinkmann V, Karlas A, Naumann M, Rother M, Machuy N, Meyer TF.

Cell Rep. 2017 Sep 5;20(10):2384-2395. doi: 10.1016/j.celrep.2017.08.039.


The cofilin phosphatase slingshot homolog 1 (SSH1) links NOD1 signaling to actin remodeling.

Bielig H, Lautz K, Braun PR, Menning M, Machuy N, Brügmann C, Barisic S, Eisler SA, Andree M, Zurek B, Kashkar H, Sansonetti PJ, Hausser A, Meyer TF, Kufer TA.

PLoS Pathog. 2014 Sep 4;10(9):e1004351. doi: 10.1371/journal.ppat.1004351. eCollection 2014 Sep.


Dynamin-mediated lipid acquisition is essential for Chlamydia trachomatis development.

Gurumurthy RK, Chumduri C, Karlas A, Kimmig S, Gonzalez E, Machuy N, Rudel T, Meyer TF.

Mol Microbiol. 2014 Oct;94(1):186-201. doi: 10.1111/mmi.12751. Epub 2014 Aug 29.


Helicobacter pylori outer membrane protein HopQ identified as a novel T4SS-associated virulence factor.

Belogolova E, Bauer B, Pompaiah M, Asakura H, Brinkman V, Ertl C, Bartfeld S, Nechitaylo TY, Haas R, Machuy N, Salama N, Churin Y, Meyer TF.

Cell Microbiol. 2013 Nov;15(11):1896-912. doi: 10.1111/cmi.12158. Epub 2013 Jul 15.


Identification of new genes involved in human adipogenesis and fat storage.

Söhle J, Machuy N, Smailbegovic E, Holtzmann U, Grönniger E, Wenck H, Stäb F, Winnefeld M.

PLoS One. 2012;7(2):e31193. doi: 10.1371/journal.pone.0031193. Epub 2012 Feb 27.


HIF-1α is involved in mediating apoptosis resistance to Chlamydia trachomatis-infected cells.

Sharma M, Machuy N, Böhme L, Karunakaran K, Mäurer AP, Meyer TF, Rudel T.

Cell Microbiol. 2011 Oct;13(10):1573-85. doi: 10.1111/j.1462-5822.2011.01642.x. Epub 2011 Aug 8.


Autophagy-independent function of MAP-LC3 during intracellular propagation of Chlamydia trachomatis.

Al-Younes HM, Al-Zeer MA, Khalil H, Gussmann J, Karlas A, Machuy N, Brinkmann V, Braun PR, Meyer TF.

Autophagy. 2011 Aug;7(8):814-28. Epub 2011 Aug 1.


A loss-of-function screen reveals Ras- and Raf-independent MEK-ERK signaling during Chlamydia trachomatis infection.

Gurumurthy RK, Mäurer AP, Machuy N, Hess S, Pleissner KP, Schuchhardt J, Rudel T, Meyer TF.

Sci Signal. 2010 Mar 16;3(113):ra21. doi: 10.1126/scisignal.2000651.


High-throughput and single-cell imaging of NF-kappaB oscillations using monoclonal cell lines.

Bartfeld S, Hess S, Bauer B, Machuy N, Ogilvie LA, Schuchhardt J, Meyer TF.

BMC Cell Biol. 2010 Mar 16;11:21. doi: 10.1186/1471-2121-11-21.


Genome-wide RNAi screen identifies human host factors crucial for influenza virus replication.

Karlas A, Machuy N, Shin Y, Pleissner KP, Artarini A, Heuer D, Becker D, Khalil H, Ogilvie LA, Hess S, Mäurer AP, Müller E, Wolff T, Rudel T, Meyer TF.

Nature. 2010 Feb 11;463(7282):818-22. doi: 10.1038/nature08760. Epub 2010 Jan 17.


Bim and Bmf synergize to induce apoptosis in Neisseria gonorrhoeae infection.

Kepp O, Gottschalk K, Churin Y, Rajalingam K, Brinkmann V, Machuy N, Kroemer G, Rudel T.

PLoS Pathog. 2009 Mar;5(3):e1000348. doi: 10.1371/journal.ppat.1000348. Epub 2009 Mar 20.


Chlamydia causes fragmentation of the Golgi compartment to ensure reproduction.

Heuer D, Rejman Lipinski A, Machuy N, Karlas A, Wehrens A, Siedler F, Brinkmann V, Meyer TF.

Nature. 2009 Feb 5;457(7230):731-5. doi: 10.1038/nature07578. Epub 2008 Dec 7.


c-Abl-binding protein interacts with p21-activated kinase 2 (PAK-2) to regulate PDGF-induced membrane ruffles.

Machuy N, Campa F, Thieck O, Rudel T.

J Mol Biol. 2007 Jul 20;370(4):620-32. Epub 2007 May 10.


IAP-IAP complexes required for apoptosis resistance of C. trachomatis-infected cells.

Rajalingam K, Sharma M, Paland N, Hurwitz R, Thieck O, Oswald M, Machuy N, Rudel T.

PLoS Pathog. 2006 Oct;2(10):e114.


NF-kappaB and inhibitor of apoptosis proteins are required for apoptosis resistance of epithelial cells persistently infected with Chlamydophila pneumoniae.

Paland N, Rajalingam K, Machuy N, Szczepek A, Wehrl W, Rudel T.

Cell Microbiol. 2006 Oct;8(10):1643-55.


The kinesin KIF1C and microtubule plus ends regulate podosome dynamics in macrophages.

Kopp P, Lammers R, Aepfelbacher M, Woehlke G, Rudel T, Machuy N, Steffen W, Linder S.

Mol Biol Cell. 2006 Jun;17(6):2811-23. Epub 2006 Mar 22.


A global approach combining proteome analysis and phenotypic screening with RNA interference yields novel apoptosis regulators.

Machuy N, Thiede B, Rajalingam K, Dimmler C, Thieck O, Meyer TF, Rudel T.

Mol Cell Proteomics. 2005 Jan;4(1):44-55. Epub 2004 Nov 26.


Hydrogen peroxide produced by Aplysia ink toxin kills tumor cells independent of apoptosis via peroxiredoxin I sensitive pathways.

Butzke D, Machuy N, Thiede B, Hurwitz R, Goedert S, Rudel T.

Cell Death Differ. 2004 Jun;11(6):608-17.


Requirement of caspase-mediated cleavage of c-Abl during stress-induced apoptosis.

Machuy N, Rajalingam K, Rudel T.

Cell Death Differ. 2004 Mar;11(3):290-300.


VDAC and the bacterial porin PorB of Neisseria gonorrhoeae share mitochondrial import pathways.

Müller A, Rassow J, Grimm J, Machuy N, Meyer TF, Rudel T.

EMBO J. 2002 Apr 15;21(8):1916-29.

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