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Items: 1 to 50 of 149

1.

Informant-based hearing difficulties and the risk for mild cognitive impairment and dementia.

Vassilaki M, Aakre JA, Knopman DS, Kremers WK, Mielke MM, Geda YE, Machulda MM, Al Fakir R, Undavalli C, Roberts RO, Petersen RC.

Age Ageing. 2019 Aug 22. pii: afz099. doi: 10.1093/ageing/afz099. [Epub ahead of print]

PMID:
31437275
2.

Clinical and neuroimaging characteristics of clinically unclassifiable primary progressive aphasia.

Utianski RL, Botha H, Martin PR, Schwarz CG, Duffy JR, Clark HM, Machulda MM, Butts AM, Lowe VJ, Jack CR Jr, Senjem ML, Spychalla AJ, Whitwell JL, Josephs KA.

Brain Lang. 2019 Aug 13;197:104676. doi: 10.1016/j.bandl.2019.104676. [Epub ahead of print]

PMID:
31419589
3.

An Evaluation of the Progressive Supranuclear Palsy Speech/Language Variant.

Whitwell JL, Stevens CA, Duffy JR, Clark HM, Machulda MM, Strand EA, Martin PR, Utianski RL, Botha H, Spychalla AJ, Senjem ML, Schwarz CG, Jack CR Jr, Ali F, Hassan A, Josephs KA.

Mov Disord Clin Pract. 2019 May 29;6(6):452-461. doi: 10.1002/mdc3.12796. eCollection 2019 Jul.

PMID:
31392246
4.

Prevalence of Biologically vs Clinically Defined Alzheimer Spectrum Entities Using the National Institute on Aging-Alzheimer's Association Research Framework.

Jack CR Jr, Therneau TM, Weigand SD, Wiste HJ, Knopman DS, Vemuri P, Lowe VJ, Mielke MM, Roberts RO, Machulda MM, Graff-Radford J, Jones DT, Schwarz CG, Gunter JL, Senjem ML, Rocca WA, Petersen RC.

JAMA Neurol. 2019 Jul 15. doi: 10.1001/jamaneurol.2019.1971. [Epub ahead of print]

5.

Quantity and quality of mental activities and the risk of incident mild cognitive impairment.

Krell-Roesch J, Syrjanen JA, Vassilaki M, Machulda MM, Mielke MM, Knopman DS, Kremers WK, Petersen RC, Geda YE.

Neurology. 2019 Aug 6;93(6):e548-e558. doi: 10.1212/WNL.0000000000007897. Epub 2019 Jul 10.

PMID:
31292224
6.

Comparison of the Short Test of Mental Status and the Montreal Cognitive Assessment Across the Cognitive Spectrum.

Townley RA, Syrjanen JA, Botha H, Kremers WK, Aakre JA, Fields JA, Machulda MM, Graff-Radford J, Savica R, Jones DT, Knopman DS, Petersen RC, Boeve BF.

Mayo Clin Proc. 2019 Aug;94(8):1516-1523. doi: 10.1016/j.mayocp.2019.01.043. Epub 2019 Jul 4.

PMID:
31280871
7.

Associations of Amyloid, Tau, and Neurodegeneration Biomarker Profiles With Rates of Memory Decline Among Individuals Without Dementia.

Jack CR Jr, Wiste HJ, Therneau TM, Weigand SD, Knopman DS, Mielke MM, Lowe VJ, Vemuri P, Machulda MM, Schwarz CG, Gunter JL, Senjem ML, Graff-Radford J, Jones DT, Roberts RO, Rocca WA, Petersen RC.

JAMA. 2019 Jun 18;321(23):2316-2325. doi: 10.1001/jama.2019.7437.

PMID:
31211344
8.

Progressive agrammatic aphasia without apraxia of speech as a distinct syndrome.

Tetzloff KA, Duffy JR, Clark HM, Utianski RL, Strand EA, Machulda MM, Botha H, Martin PR, Schwarz CG, Senjem ML, Reid RI, Gunter JL, Spychalla AJ, Knopman DS, Petersen RC, Jack CR, Lowe VJ, Josephs KA, Whitwell JL.

Brain. 2019 Aug 1;142(8):2466-2482. doi: 10.1093/brain/awz157.

PMID:
31199471
9.

Plasma and CSF neurofilament light: Relation to longitudinal neuroimaging and cognitive measures.

Mielke MM, Syrjanen JA, Blennow K, Zetterberg H, Vemuri P, Skoog I, Machulda MM, Kremers WK, Knopman DS, Jack C Jr, Petersen RC, Kern S.

Neurology. 2019 Jul 16;93(3):e252-e260. doi: 10.1212/WNL.0000000000007767. Epub 2019 Jun 10.

10.

Cross-sectional associations of tau-PET signal with cognition in cognitively unimpaired adults.

Lowe VJ, Bruinsma TJ, Wiste HJ, Min HK, Weigand SD, Fang P, Senjem ML, Therneau TM, Boeve BF, Josephs KA, Pandey MK, Murray ME, Kantarci K, Jones DT, Vemuri P, Graff-Radford J, Schwarz CG, Machulda MM, Mielke MM, Roberts RO, Knopman DS, Petersen RC, Jack CR Jr.

Neurology. 2019 Jul 2;93(1):e29-e39. doi: 10.1212/WNL.0000000000007728. Epub 2019 May 30.

PMID:
31147421
11.

Neuropsychological subtypes of incident mild cognitive impairment in the Mayo Clinic Study of Aging.

Machulda MM, Lundt ES, Albertson SM, Kremers WK, Mielke MM, Knopman DS, Bondi MW, Petersen RC.

Alzheimers Dement. 2019 Jul;15(7):878-887. doi: 10.1016/j.jalz.2019.03.014. Epub 2019 May 23.

PMID:
31128864
12.

Longitudinal association between phosphatidylcholines, neuroimaging measures of Alzheimer's disease pathophysiology, and cognition in the Mayo Clinic Study of Aging.

Li D, Hagen C, Fett AR, Bui HH, Knopman D, Vemuri P, Machulda MM, Jack CR Jr, Petersen RC, Mielke MM.

Neurobiol Aging. 2019 Jul;79:43-49. doi: 10.1016/j.neurobiolaging.2019.03.005. Epub 2019 Mar 18.

PMID:
31026621
13.

Longitudinal tau-PET uptake and atrophy in atypical Alzheimer's disease.

Sintini I, Martin PR, Graff-Radford J, Senjem ML, Schwarz CG, Machulda MM, Spychalla AJ, Drubach DA, Knopman DS, Petersen RC, Lowe VJ, Jack CR Jr, Josephs KA, Whitwell JL.

Neuroimage Clin. 2019 Apr 10;23:101823. doi: 10.1016/j.nicl.2019.101823. [Epub ahead of print]

14.

Cortical β-amyloid burden, neuropsychiatric symptoms, and cognitive status: the Mayo Clinic Study of Aging.

Krell-Roesch J, Vassilaki M, Mielke MM, Kremers WK, Lowe VJ, Vemuri P, Machulda MM, Christianson TJ, Syrjanen JA, Stokin GB, Butler LM, Traber M, Jack CR Jr, Knopman DS, Roberts RO, Petersen RC, Geda YE.

Transl Psychiatry. 2019 Mar 28;9(1):123. doi: 10.1038/s41398-019-0456-z.

15.

Prominent auditory deficits in primary progressive aphasia: A case study.

Utianski RL, Duffy JR, Clark HM, Machulda MM, Dickson DW, Whitwell JL, Josephs KA.

Cortex. 2019 Aug;117:396-406. doi: 10.1016/j.cortex.2019.01.021. Epub 2019 Feb 21.

PMID:
30878181
16.

The role of age on tau PET uptake and gray matter atrophy in atypical Alzheimer's disease.

Whitwell JL, Martin P, Graff-Radford J, Machulda MM, Senjem ML, Schwarz CG, Weigand SD, Spychalla AJ, Drubach DA, Jack CR Jr, Lowe VJ, Josephs KA.

Alzheimers Dement. 2019 May;15(5):675-685. doi: 10.1016/j.jalz.2018.12.016. Epub 2019 Mar 8.

PMID:
30853465
17.

The metabolic brain signature of cognitive resilience in the 80+: beyond Alzheimer pathologies.

Arenaza-Urquijo EM, Przybelski SA, Lesnick TL, Graff-Radford J, Machulda MM, Knopman DS, Schwarz CG, Lowe VJ, Mielke MM, Petersen RC, Jack CR, Vemuri P.

Brain. 2019 Apr 1;142(4):1134-1147. doi: 10.1093/brain/awz037.

PMID:
30851100
18.

The influence of tau, amyloid, alpha-synuclein, TDP-43, and vascular pathology in clinically normal elderly individuals.

Wennberg AM, Whitwell JL, Tosakulwong N, Weigand SD, Murray ME, Machulda MM, Petrucelli L, Mielke MM, Jack CR Jr, Knopman DS, Parisi JE, Petersen RC, Dickson DW, Josephs KA.

Neurobiol Aging. 2019 May;77:26-36. doi: 10.1016/j.neurobiolaging.2019.01.008. Epub 2019 Jan 21.

PMID:
30776649
19.

Entorhinal cortex tau, amyloid-β, cortical thickness and memory performance in non-demented subjects.

Knopman DS, Lundt ES, Therneau TM, Vemuri P, Lowe VJ, Kantarci K, Gunter JL, Senjem ML, Mielke MM, Machulda MM, Boeve BF, Jones DT, Graff-Radford J, Albertson SM, Schwarz CG, Petersen RC, Jack CR.

Brain. 2019 Apr 1;142(4):1148-1160. doi: 10.1093/brain/awz025.

PMID:
30759182
20.

The influence of β-amyloid on [18F]AV-1451 in semantic variant of primary progressive aphasia.

Whitwell JL, Martin PR, Duffy JR, Clark HM, Machulda MM, Schwarz CG, Weigand SD, Sintini I, Senjem ML, Ertekin-Taner N, Botha H, Utianski RL, Graff-Radford J, Jones DT, Boeve BF, Knopman DS, Petersen RC, Jack CR Jr, Lowe VJ, Josephs KA.

Neurology. 2019 Feb 12;92(7):e710-e722. doi: 10.1212/WNL.0000000000006913. Epub 2019 Jan 11.

PMID:
30635491
21.

Rapid rate on quasi-speech tasks in the semantic variant of primary progressive aphasia: A non-motor phenomenon?

Utianski RL, Botha H, Duffy JR, Clark HM, Martin PR, Butts AM, Machulda MM, Whitwell JL, Josephs KA.

J Acoust Soc Am. 2018 Dec;144(6):3364. doi: 10.1121/1.5082210.

PMID:
30599666
22.

Regional multimodal relationships between tau, hypometabolism, atrophy, and fractional anisotropy in atypical Alzheimer's disease.

Sintini I, Schwarz CG, Martin PR, Graff-Radford J, Machulda MM, Senjem ML, Reid RI, Spychalla AJ, Drubach DA, Lowe VJ, Jack CR Jr, Josephs KA, Whitwell JL.

Hum Brain Mapp. 2019 Apr 1;40(5):1618-1631. doi: 10.1002/hbm.24473. Epub 2018 Dec 13.

23.

Predicting Progression to Mild Cognitive Impairment.

Petersen RC, Lundt ES, Therneau TM, Weigand SD, Knopman DS, Mielke MM, Roberts RO, Lowe VJ, Machulda MM, Kremers WK, Geda YE, Jack CR Jr.

Ann Neurol. 2019 Jan;85(1):155-160. doi: 10.1002/ana.25388. Epub 2019 Jan 7.

PMID:
30521086
24.

Association Between Functional Performance and Alzheimer's Disease Biomarkers in Individuals Without Dementia.

Vassilaki M, Aakre JA, Kremers WK, Mielke MM, Geda YE, Machulda MM, Knopman DS, Coloma PM, Schauble B, Vemuri P, Lowe VJ, Jack CR Jr, Petersen RC, Roberts RO.

J Am Geriatr Soc. 2018 Dec;66(12):2274-2281. doi: 10.1111/jgs.15577. Epub 2018 Nov 21.

PMID:
30462843
25.

Clinical Progression in Four Cases of Primary Progressive Apraxia of Speech.

Utianski RL, Duffy JR, Clark HM, Strand EA, Boland SM, Machulda MM, Whitwell JL, Josephs KA.

Am J Speech Lang Pathol. 2018 Nov 21;27(4):1303-1318. doi: 10.1044/2018_AJSLP-17-0227.

26.

Comparison of PC and iPad administrations of the Cogstate Brief Battery in the Mayo Clinic Study of Aging: Assessing cross-modality equivalence of computerized neuropsychological tests.

Stricker NH, Lundt ES, Edwards KK, Machulda MM, Kremers WK, Roberts RO, Knopman DS, Petersen RC, Mielke MM.

Clin Neuropsychol. 2019 Aug;33(6):1102-1126. doi: 10.1080/13854046.2018.1519085. Epub 2018 Nov 10.

PMID:
30417735
27.

Patterns of Neuropsychological Dysfunction and Cortical Volume Changes in Logopenic Aphasia.

Owens TE, Machulda MM, Duffy JR, Strand EA, Clark HM, Boland S, Martin PR, Lowe VJ, Jack CR, Whitwell JL, Josephs KA.

J Alzheimers Dis. 2018;66(3):1015-1025. doi: 10.3233/JAD-171175.

28.

Development of a cerebrovascular magnetic resonance imaging biomarker for cognitive aging.

Vemuri P, Lesnick TG, Przybelski SA, Graff-Radford J, Reid RI, Lowe VJ, Zuk SM, Senjem ML, Schwarz CG, Gunter JL, Kantarci K, Machulda MM, Mielke MM, Petersen RC, Knopman DS, Jack CR Jr.

Ann Neurol. 2018 Nov;84(5):705-716. doi: 10.1002/ana.25346. Epub 2018 Oct 25.

29.

The Cross-Sectional and Longitudinal Associations Between IL-6, IL-10, and TNFα and Cognitive Outcomes in the Mayo Clinic Study of Aging.

Wennberg AMV, Hagen CE, Machulda MM, Knopman DS, Petersen RC, Mielke MM.

J Gerontol A Biol Sci Med Sci. 2018 Sep 25. doi: 10.1093/gerona/gly217. [Epub ahead of print]

PMID:
30256904
30.

Quantitative assessment of grammar in amyloid-negative logopenic aphasia.

Tetzloff KA, Whitwell JL, Utianski RL, Duffy JR, Clark HM, Machulda MM, Strand EA, Josephs KA.

Brain Lang. 2018 Nov;186:26-31. doi: 10.1016/j.bandl.2018.09.003. Epub 2018 Sep 8.

PMID:
30205287
31.

The Association of Multimorbidity With Preclinical AD Stages and SNAP in Cognitively Unimpaired Persons.

Vassilaki M, Aakre JA, Kremers WK, Mielke MM, Geda YE, Alhurani RE, Dutt T, Machulda MM, Knopman DS, Vemuri P, Coloma PM, Schauble B, Lowe VJ, Jack CR, Petersen RC, Roberts RO.

J Gerontol A Biol Sci Med Sci. 2019 May 16;74(6):877-883. doi: 10.1093/gerona/gly149.

32.

Functional Activity and Neuropsychiatric Symptoms in Normal Aging and Mild Cognitive Impairment: The Mayo Clinic Study of Aging.

Krell-Roesch J, Cerhan LP, Machulda MM, Roberts RO, Mielke MM, Knopman DS, Syrjanen JA, Christianson TJ, Petersen RC, Geda YE.

Alzheimer Dis Assoc Disord. 2019 Jan-Mar;33(1):68-71. doi: 10.1097/WAD.0000000000000266. No abstract available.

PMID:
30106755
33.

TDP-43 and Alzheimer's Disease Pathologic Subtype in Non-Amnestic Alzheimer's Disease Dementia.

Sahoo A, Bejanin A, Murray ME, Tosakulwong N, Weigand SD, Serie AM, Senjem ML, Machulda MM, Parisi JE, Boeve BF, Knopman DS, Petersen RC, Dickson DW, Whitwell JL, Josephs KA.

J Alzheimers Dis. 2018;64(4):1227-1233. doi: 10.3233/JAD-180169.

34.

Prosodic and phonetic subtypes of primary progressive apraxia of speech.

Utianski RL, Duffy JR, Clark HM, Strand EA, Botha H, Schwarz CG, Machulda MM, Senjem ML, Spychalla AJ, Jack CR Jr, Petersen RC, Lowe VJ, Whitwell JL, Josephs KA.

Brain Lang. 2018 Sep;184:54-65. doi: 10.1016/j.bandl.2018.06.004. Epub 2018 Jul 4.

35.

Tau uptake in agrammatic primary progressive aphasia with and without apraxia of speech.

Utianski RL, Whitwell JL, Schwarz CG, Duffy JR, Botha H, Clark HM, Machulda MM, Senjem ML, Knopman DS, Petersen RC, Jack CR Jr, Lowe VJ, Josephs KA.

Eur J Neurol. 2018 Nov;25(11):1352-1357. doi: 10.1111/ene.13733. Epub 2018 Jul 26.

PMID:
29935044
36.

Mediterranean Diet, Its Components, and Amyloid Imaging Biomarkers.

Vassilaki M, Aakre JA, Syrjanen JA, Mielke MM, Geda YE, Kremers WK, Machulda MM, Alhurani RE, Staubo SC, Knopman DS, Petersen RC, Lowe VJ, Jack CR, Roberts RO.

J Alzheimers Dis. 2018;64(1):281-290. doi: 10.3233/JAD-171121.

37.

Association of antidiabetic medication use, cognitive decline, and risk of cognitive impairment in older people with type 2 diabetes: Results from the population-based Mayo Clinic Study of Aging.

Wennberg AMV, Hagen CE, Edwards K, Roberts RO, Machulda MM, Knopman DS, Petersen RC, Mielke MM.

Int J Geriatr Psychiatry. 2018 Aug;33(8):1114-1120. doi: 10.1002/gps.4900. Epub 2018 Jun 5.

38.

Disrupted functional connectivity in primary progressive apraxia of speech.

Botha H, Utianski RL, Whitwell JL, Duffy JR, Clark HM, Strand EA, Machulda MM, Tosakulwong N, Knopman DS, Petersen RC, Jack CR Jr, Josephs KA, Jones DT.

Neuroimage Clin. 2018 Mar 3;18:617-629. doi: 10.1016/j.nicl.2018.02.036. eCollection 2018.

39.

Non-right handed primary progressive apraxia of speech.

Botha H, Duffy JR, Whitwell JL, Strand EA, Machulda MM, Spychalla AJ, Tosakulwong N, Senjem ML, Knopman DS, Petersen RC, Jack CR Jr, Lowe VJ, Josephs KA.

J Neurol Sci. 2018 Jul 15;390:246-254. doi: 10.1016/j.jns.2018.05.007. Epub 2018 May 7.

40.

Clinical and imaging progression over 10 years in a patient with primary progressive apraxia of speech and autopsy-confirmed corticobasal degeneration.

Tetzloff KA, Duffy JR, Strand EA, Machulda MM, Boland SM, Utianski RL, Botha H, Senjem ML, Schwarz CG, Josephs KA, Whitwell JL.

Neurocase. 2018 Apr;24(2):111-120. doi: 10.1080/13554794.2018.1477963. Epub 2018 May 25.

41.

Prevalence and Outcomes of Amyloid Positivity Among Persons Without Dementia in a Longitudinal, Population-Based Setting.

Roberts RO, Aakre JA, Kremers WK, Vassilaki M, Knopman DS, Mielke MM, Alhurani R, Geda YE, Machulda MM, Coloma P, Schauble B, Lowe VJ, Jack CR Jr, Petersen RC.

JAMA Neurol. 2018 Aug 1;75(8):970-979. doi: 10.1001/jamaneurol.2018.0629.

42.

Plasma phospho-tau181 increases with Alzheimer's disease clinical severity and is associated with tau- and amyloid-positron emission tomography.

Mielke MM, Hagen CE, Xu J, Chai X, Vemuri P, Lowe VJ, Airey DC, Knopman DS, Roberts RO, Machulda MM, Jack CR Jr, Petersen RC, Dage JL.

Alzheimers Dement. 2018 Aug;14(8):989-997. doi: 10.1016/j.jalz.2018.02.013. Epub 2018 Apr 5.

43.

Regional Distribution, Asymmetry, and Clinical Correlates of Tau Uptake on [18F]AV-1451 PET in Atypical Alzheimer's Disease.

Tetzloff KA, Graff-Radford J, Martin PR, Tosakulwong N, Machulda MM, Duffy JR, Clark HM, Senjem ML, Schwarz CG, Spychalla AJ, Drubach DA, Jack CR, Lowe VJ, Josephs KA, Whitwell JL.

J Alzheimers Dis. 2018;62(4):1713-1724. doi: 10.3233/JAD-170740.

44.

Imaging correlations of tau, amyloid, metabolism, and atrophy in typical and atypical Alzheimer's disease.

Whitwell JL, Graff-Radford J, Tosakulwong N, Weigand SD, Machulda MM, Senjem ML, Spychalla AJ, Vemuri P, Jones DT, Drubach DA, Knopman DS, Boeve BF, Ertekin-Taner N, Petersen RC, Lowe VJ, Jack CR Jr, Josephs KA.

Alzheimers Dement. 2018 Aug;14(8):1005-1014. doi: 10.1016/j.jalz.2018.02.020. Epub 2018 Mar 30.

45.

Molecular neuroimaging in primary progressive aphasia with predominant agraphia.

Utianski RL, Duffy JR, Savica R, Whitwell JL, Machulda MM, Josephs KA.

Neurocase. 2018 Apr;24(2):121-123. doi: 10.1080/13554794.2018.1454963. Epub 2018 Mar 23.

46.

Clinicopathological and 123I-FP-CIT SPECT correlations in patients with dementia.

Jung Y, Jordan LG 3rd, Lowe VJ, Kantarci K, Parisi JE, Dickson DW, Murray ME, Reichard RR, Ferman TJ, Jones DT, Graff-Radford J, Savica R, Machulda MM, Fields JA, Allen LA, Drubach DA, St Louis EK, Silber MH, Jack CR Jr, Knopman DS, Petersen RC, Boeve BF.

Ann Clin Transl Neurol. 2018 Jan 24;5(3):376-381. doi: 10.1002/acn3.521. eCollection 2018 Mar.

47.

The association between peripheral total IGF-1, IGFBP-3, and IGF-1/IGFBP-3 and functional and cognitive outcomes in the Mayo Clinic Study of Aging.

Wennberg AMV, Hagen CE, Machulda MM, Hollman JH, Roberts RO, Knopman DS, Petersen RC, Mielke MM.

Neurobiol Aging. 2018 Jun;66:68-74. doi: 10.1016/j.neurobiolaging.2017.11.017. Epub 2018 Feb 19.

48.

FDG-PET in tau-negative amnestic dementia resembles that of autopsy-proven hippocampal sclerosis.

Botha H, Mantyh WG, Murray ME, Knopman DS, Przybelski SA, Wiste HJ, Graff-Radford J, Josephs KA, Schwarz CG, Kremers WK, Boeve BF, Petersen RC, Machulda MM, Parisi JE, Dickson DW, Lowe V, Jack CR Jr, Jones DT.

Brain. 2018 Apr 1;141(4):1201-1217. doi: 10.1093/brain/awy049.

49.

Longitudinal tau PET in ageing and Alzheimer's disease.

Jack CR Jr, Wiste HJ, Schwarz CG, Lowe VJ, Senjem ML, Vemuri P, Weigand SD, Therneau TM, Knopman DS, Gunter JL, Jones DT, Graff-Radford J, Kantarci K, Roberts RO, Mielke MM, Machulda MM, Petersen RC.

Brain. 2018 May 1;141(5):1517-1528. doi: 10.1093/brain/awy059.

50.

Association of Excessive Daytime Sleepiness With Longitudinal β-Amyloid Accumulation in Elderly Persons Without Dementia.

Carvalho DZ, St Louis EK, Knopman DS, Boeve BF, Lowe VJ, Roberts RO, Mielke MM, Przybelski SA, Machulda MM, Petersen RC, Jack CR Jr, Vemuri P.

JAMA Neurol. 2018 Jun 1;75(6):672-680. doi: 10.1001/jamaneurol.2018.0049.

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