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Items: 1 to 50 of 117

1.

TDP-43 and Alzheimer's Disease Pathologic Subtype in Non-Amnestic Alzheimer's Disease Dementia.

Sahoo A, Benjanin A, Murray ME, Tosakulwong N, Weigand SD, Serie AM, Senjem ML, Machulda MM, Parisi JE, Boeve BF, Knopman DS, Petersen RC, Dickson DW, Whitwell JL, Josephs KA.

J Alzheimers Dis. 2018 Jun 28. doi: 10.3233/JAD-180169. [Epub ahead of print]

PMID:
30010126
2.

Prosodic and phonetic subtypes of primary progressive apraxia of speech.

Utianski RL, Duffy JR, Clark HM, Strand EA, Botha H, Schwarz CG, Machulda MM, Senjem ML, Spychalla AJ, Jack CR Jr, Petersen RC, Lowe VJ, Whitwell JL, Josephs KA.

Brain Lang. 2018 Jul 3;184:54-65. doi: 10.1016/j.bandl.2018.06.004. [Epub ahead of print]

PMID:
29980072
3.

Tau Uptake in Agrammatic Primary Progressive Aphasia with and without Apraxia of Speech.

Utianski RL, Whitwell JL, Schwarz CG, Duffy JR, Botha H, Clark HM, Machulda MM, Senjem ML, Knopman DS, Petersen RC, Jack CR Jr, Lowe VJ, Josephs KA.

Eur J Neurol. 2018 Jun 23. doi: 10.1111/ene.13733. [Epub ahead of print]

PMID:
29935044
4.

Mediterranean Diet, Its Components, and Amyloid Imaging Biomarkers.

Vassilaki M, Aakre JA, Syrjanen JA, Mielke MM, Geda YE, Kremers WK, Machulda MM, Alhurani RE, Staubo SC, Knopman DS, Petersen RC, Lowe VJ, Jack CR, Roberts RO.

J Alzheimers Dis. 2018;64(1):281-290. doi: 10.3233/JAD-171121.

PMID:
29889074
5.

Association of antidiabetic medication use, cognitive decline, and risk of cognitive impairment in older people with type 2 diabetes: Results from the population-based Mayo Clinic Study of Aging.

Wennberg AMV, Hagen CE, Edwards K, Roberts RO, Machulda MM, Knopman DS, Petersen RC, Mielke MM.

Int J Geriatr Psychiatry. 2018 Aug;33(8):1114-1120. doi: 10.1002/gps.4900. Epub 2018 Jun 5.

PMID:
29873112
6.

Disrupted functional connectivity in primary progressive apraxia of speech.

Botha H, Utianski RL, Whitwell JL, Duffy JR, Clark HM, Strand EA, Machulda MM, Tosakulwong N, Knopman DS, Petersen RC, Jack CR Jr, Josephs KA, Jones DT.

Neuroimage Clin. 2018 Mar 3;18:617-629. doi: 10.1016/j.nicl.2018.02.036. eCollection 2018.

7.

Non-right handed primary progressive apraxia of speech.

Botha H, Duffy JR, Whitwell JL, Strand EA, Machulda MM, Spychalla AJ, Tosakulwong N, Senjem ML, Knopman DS, Petersen RC, Jack CR Jr, Lowe VJ, Josephs KA.

J Neurol Sci. 2018 Jul 15;390:246-254. doi: 10.1016/j.jns.2018.05.007. Epub 2018 May 7.

PMID:
29801898
8.

Clinical and imaging progression over 10 years in a patient with primary progressive apraxia of speech and autopsy-confirmed corticobasal degeneration.

Tetzloff KA, Duffy JR, Strand EA, Machulda MM, Boland SM, Utianski RL, Botha H, Senjem ML, Schwarz CG, Josephs KA, Whitwell JL.

Neurocase. 2018 Apr;24(2):111-120. doi: 10.1080/13554794.2018.1477963. Epub 2018 May 25.

PMID:
29799310
9.

Prevalence and Outcomes of Amyloid Positivity Among Persons Without Dementia in a Longitudinal, Population-Based Setting.

Roberts RO, Aakre JA, Kremers WK, Vassilaki M, Knopman DS, Mielke MM, Alhurani R, Geda YE, Machulda MM, Coloma P, Schauble B, Lowe VJ, Jack CR Jr, Petersen RC.

JAMA Neurol. 2018 Apr 30. doi: 10.1001/jamaneurol.2018.0629. [Epub ahead of print]

PMID:
29710225
10.

Plasma phospho-tau181 increases with Alzheimer's disease clinical severity and is associated with tau- and amyloid-positron emission tomography.

Mielke MM, Hagen CE, Xu J, Chai X, Vemuri P, Lowe VJ, Airey DC, Knopman DS, Roberts RO, Machulda MM, Jack CR Jr, Petersen RC, Dage JL.

Alzheimers Dement. 2018 Apr 5. pii: S1552-5260(18)30067-0. doi: 10.1016/j.jalz.2018.02.013. [Epub ahead of print]

PMID:
29626426
11.

Regional Distribution, Asymmetry, and Clinical Correlates of Tau Uptake on [18F]AV-1451 PET in Atypical Alzheimer's Disease.

Tetzloff KA, Graff-Radford J, Martin PR, Tosakulwong N, Machulda MM, Duffy JR, Clark HM, Senjem ML, Schwarz CG, Spychalla AJ, Drubach DA, Jack CR, Lowe VJ, Josephs KA, Whitwell JL.

J Alzheimers Dis. 2018;62(4):1713-1724. doi: 10.3233/JAD-170740.

PMID:
29614676
12.

Imaging correlations of tau, amyloid, metabolism, and atrophy in typical and atypical Alzheimer's disease.

Whitwell JL, Graff-Radford J, Tosakulwong N, Weigand SD, Machulda MM, Senjem ML, Spychalla AJ, Vemuri P, Jones DT, Drubach DA, Knopman DS, Boeve BF, Ertekin-Taner N, Petersen RC, Lowe VJ, Jack CR Jr, Josephs KA.

Alzheimers Dement. 2018 Mar 30. pii: S1552-5260(18)30074-8. doi: 10.1016/j.jalz.2018.02.020. [Epub ahead of print]

PMID:
29605222
13.

Molecular neuroimaging in primary progressive aphasia with predominant agraphia.

Utianski RL, Duffy JR, Savica R, Whitwell JL, Machulda MM, Josephs KA.

Neurocase. 2018 Apr;24(2):121-123. doi: 10.1080/13554794.2018.1454963. Epub 2018 Mar 23.

PMID:
29569990
14.

Clinicopathological and 123I-FP-CIT SPECT correlations in patients with dementia.

Jung Y, Jordan LG 3rd, Lowe VJ, Kantarci K, Parisi JE, Dickson DW, Murray ME, Reichard RR, Ferman TJ, Jones DT, Graff-Radford J, Savica R, Machulda MM, Fields JA, Allen LA, Drubach DA, St Louis EK, Silber MH, Jack CR Jr, Knopman DS, Petersen RC, Boeve BF.

Ann Clin Transl Neurol. 2018 Jan 24;5(3):376-381. doi: 10.1002/acn3.521. eCollection 2018 Mar.

15.

The association between peripheral total IGF-1, IGFBP-3, and IGF-1/IGFBP-3 and functional and cognitive outcomes in the Mayo Clinic Study of Aging.

Wennberg AMV, Hagen CE, Machulda MM, Hollman JH, Roberts RO, Knopman DS, Petersen RC, Mielke MM.

Neurobiol Aging. 2018 Jun;66:68-74. doi: 10.1016/j.neurobiolaging.2017.11.017. Epub 2018 Feb 19.

PMID:
29547749
16.

FDG-PET in tau-negative amnestic dementia resembles that of autopsy-proven hippocampal sclerosis.

Botha H, Mantyh WG, Murray ME, Knopman DS, Przybelski SA, Wiste HJ, Graff-Radford J, Josephs KA, Schwarz CG, Kremers WK, Boeve BF, Petersen RC, Machulda MM, Parisi JE, Dickson DW, Lowe V, Jack CR Jr, Jones DT.

Brain. 2018 Apr 1;141(4):1201-1217. doi: 10.1093/brain/awy049.

PMID:
29538658
17.

Longitudinal tau PET in ageing and Alzheimer's disease.

Jack CR Jr, Wiste HJ, Schwarz CG, Lowe VJ, Senjem ML, Vemuri P, Weigand SD, Therneau TM, Knopman DS, Gunter JL, Jones DT, Graff-Radford J, Kantarci K, Roberts RO, Mielke MM, Machulda MM, Petersen RC.

Brain. 2018 May 1;141(5):1517-1528. doi: 10.1093/brain/awy059.

18.

Association of Excessive Daytime Sleepiness With Longitudinal β-Amyloid Accumulation in Elderly Persons Without Dementia.

Carvalho DZ, St Louis EK, Knopman DS, Boeve BF, Lowe VJ, Roberts RO, Mielke MM, Przybelski SA, Machulda MM, Petersen RC, Jack CR Jr, Vemuri P.

JAMA Neurol. 2018 Jun 1;75(6):672-680. doi: 10.1001/jamaneurol.2018.0049.

PMID:
29532057
19.

Joint associations of β-amyloidosis and cortical thickness with cognition.

Knopman DS, Lundt ES, Therneau TM, Vemuri P, Lowe VJ, Kantarci K, Gunter JL, Senjem ML, Mielke MM, Machulda MM, Roberts RO, Boeve BF, Jones DT, Petersen RC, Jack CR Jr.

Neurobiol Aging. 2018 May;65:121-131. doi: 10.1016/j.neurobiolaging.2018.01.017. Epub 2018 Feb 2.

PMID:
29471214
20.

[18 F]AV-1451 tau-PET and primary progressive aphasia.

Josephs KA, Martin PR, Botha H, Schwarz CG, Duffy JR, Clark HM, Machulda MM, Graff-Radford J, Weigand SD, Senjem ML, Utianski RL, Drubach DA, Boeve BF, Jones DT, Knopman DS, Petersen RC, Jack CR Jr, Lowe VJ, Whitwell JL.

Ann Neurol. 2018 Mar;83(3):599-611. doi: 10.1002/ana.25183. Epub 2018 Mar 13.

PMID:
29451323
21.

Tau-negative amnestic dementia masquerading as Alzheimer disease dementia.

Botha H, Mantyh WG, Graff-Radford J, Machulda MM, Przybelski SA, Wiste HJ, Senjem ML, Parisi JE, Petersen RC, Murray ME, Boeve BF, Lowe VJ, Knopman DS, Jack CR Jr, Jones DT.

Neurology. 2018 Mar 13;90(11):e940-e946. doi: 10.1212/WNL.0000000000005124. Epub 2018 Feb 7.

PMID:
29438037
22.

Tau-PET imaging with [18F]AV-1451 in primary progressive apraxia of speech.

Utianski RL, Whitwell JL, Schwarz CG, Senjem ML, Tosakulwong N, Duffy JR, Clark HM, Machulda MM, Petersen RC, Jack CR Jr, Lowe VJ, Josephs KA.

Cortex. 2018 Feb;99:358-374. doi: 10.1016/j.cortex.2017.12.021. Epub 2018 Jan 2.

PMID:
29353121
23.

Sex differences in cerebrovascular pathologies on FLAIR in cognitively unimpaired elderly.

Fatemi F, Kantarci K, Graff-Radford J, Preboske GM, Weigand SD, Przybelski SA, Knopman DS, Machulda MM, Roberts RO, Mielke MM, Petersen RC, Jack CR Jr, Vemuri P.

Neurology. 2018 Feb 6;90(6):e466-e473. doi: 10.1212/WNL.0000000000004913. Epub 2018 Jan 17.

PMID:
29343465
24.

Novel GRN mutation presenting as an aphasic dementia and evolving into corticobasal syndrome.

Botha H, Finch NA, Gavrilova RH, Machulda MM, Fields JA, Lowe VJ, Petersen RC, Jack CR Jr, Dheel CM, Gearhart DJ, Knopman DS, Rademakers R, Boeve BF.

Neurol Genet. 2017 Dec 11;3(6):e201. doi: 10.1212/NXG.0000000000000201. eCollection 2017 Dec. No abstract available.

25.

Widespread brain tau and its association with ageing, Braak stage and Alzheimer's dementia.

Lowe VJ, Wiste HJ, Senjem ML, Weigand SD, Therneau TM, Boeve BF, Josephs KA, Fang P, Pandey MK, Murray ME, Kantarci K, Jones DT, Vemuri P, Graff-Radford J, Schwarz CG, Machulda MM, Mielke MM, Roberts RO, Knopman DS, Petersen RC, Jack CR Jr.

Brain. 2018 Jan 1;141(1):271-287. doi: 10.1093/brain/awx320.

PMID:
29228201
26.

Longitudinal structural and molecular neuroimaging in agrammatic primary progressive aphasia.

Tetzloff KA, Duffy JR, Clark HM, Strand EA, Machulda MM, Schwarz CG, Senjem ML, Reid RI, Spychalla AJ, Tosakulwong N, Lowe VJ, Jack CR Jr, Josephs KA, Whitwell JL.

Brain. 2018 Jan 1;141(1):302-317. doi: 10.1093/brain/awx293.

PMID:
29228180
27.

Predicting clinical decline in progressive agrammatic aphasia and apraxia of speech.

Whitwell JL, Weigand SD, Duffy JR, Clark HM, Strand EA, Machulda MM, Spychalla AJ, Senjem ML, Jack CR Jr, Josephs KA.

Neurology. 2017 Nov 28;89(22):2271-2279. doi: 10.1212/WNL.0000000000004685. Epub 2017 Nov 1.

PMID:
29093069
28.

Weighting and standardization of frequencies to determine prevalence of AD imaging biomarkers.

Roberts RO, Knopman DS, Syrjanen JA, Aakre JA, Vassilaki M, Kremers WK, Mielke MM, Machulda MM, Graff-Radford J, Geda YE, Vemuri P, Lowe V, Jack CR Jr, Petersen RC.

Neurology. 2017 Nov 14;89(20):2039-2048. doi: 10.1212/WNL.0000000000004652. Epub 2017 Oct 13.

PMID:
29030451
29.

Age, vascular health, and Alzheimer disease biomarkers in an elderly sample.

Vemuri P, Lesnick TG, Przybelski SA, Knopman DS, Lowe VJ, Graff-Radford J, Roberts RO, Mielke MM, Machulda MM, Petersen RC, Jack CR Jr.

Ann Neurol. 2017 Nov;82(5):706-718. doi: 10.1002/ana.25071. Epub 2017 Oct 26.

PMID:
29023983
30.

1H-MRS metabolites and rate of β-amyloid accumulation on serial PET in clinically normal adults.

Nedelska Z, Przybelski SA, Lesnick TG, Schwarz CG, Lowe VJ, Machulda MM, Kremers WK, Mielke MM, Roberts RO, Boeve BF, Knopman DS, Petersen RC, Jack CR Jr, Kantarci K.

Neurology. 2017 Sep 26;89(13):1391-1399. doi: 10.1212/WNL.0000000000004421. Epub 2017 Aug 25.

31.

Association of Plasma Total Tau Level With Cognitive Decline and Risk of Mild Cognitive Impairment or Dementia in the Mayo Clinic Study on Aging.

Mielke MM, Hagen CE, Wennberg AMV, Airey DC, Savica R, Knopman DS, Machulda MM, Roberts RO, Jack CR Jr, Petersen RC, Dage JL.

JAMA Neurol. 2017 Sep 1;74(9):1073-1080. doi: 10.1001/jamaneurol.2017.1359.

PMID:
28692710
32.

Decreased Glutamate Levels in Patients with Amnestic Mild Cognitive Impairment: An sLASER Proton MR Spectroscopy and PiB-PET Study.

Zeydan B, Deelchand DK, Tosakulwong N, Lesnick TG, Kantarci OH, Machulda MM, Knopman DS, Lowe VJ, Jack CR Jr, Petersen RC, Öz G, Kantarci K.

J Neuroimaging. 2017 Nov;27(6):630-636. doi: 10.1111/jon.12454. Epub 2017 Jun 29.

PMID:
28661060
33.

Neurocognition in individuals with incidentally-identified meningioma.

Butts AM, Weigand S, Brown PD, Petersen RC, Jack CR Jr, Machulda MM, Cerhan JH.

J Neurooncol. 2017 Aug;134(1):125-132. doi: 10.1007/s11060-017-2495-8. Epub 2017 May 25.

PMID:
28547588
34.

Neuroimaging biomarkers and impaired olfaction in cognitively normal individuals.

Vassilaki M, Christianson TJ, Mielke MM, Geda YE, Kremers WK, Machulda MM, Knopman DS, Petersen RC, Lowe VJ, Jack CR Jr, Roberts RO.

Ann Neurol. 2017 Jun;81(6):871-882. doi: 10.1002/ana.24960. Epub 2017 Jun 9.

35.

Pittsburgh compound-B PET white matter imaging and cognitive function in late multiple sclerosis.

Zeydan B, Lowe VJ, Schwarz CG, Przybelski SA, Tosakulwong N, Zuk SM, Senjem ML, Gunter JL, Roberts RO, Mielke MM, Benarroch EE, Rodriguez M, Machulda MM, Lesnick TG, Knopman DS, Petersen RC, Jack CR Jr, Kantarci K, Kantarci OH.

Mult Scler. 2018 May;24(6):739-749. doi: 10.1177/1352458517707346. Epub 2017 May 5.

PMID:
28474977
36.

Age-specific and sex-specific prevalence of cerebral β-amyloidosis, tauopathy, and neurodegeneration in cognitively unimpaired individuals aged 50-95 years: a cross-sectional study.

Jack CR Jr, Wiste HJ, Weigand SD, Therneau TM, Knopman DS, Lowe V, Vemuri P, Mielke MM, Roberts RO, Machulda MM, Senjem ML, Gunter JL, Rocca WA, Petersen RC.

Lancet Neurol. 2017 Jun;16(6):435-444. doi: 10.1016/S1474-4422(17)30077-7. Epub 2017 Apr 26.

37.

Evaluation of Amyloid Protective Factors and Alzheimer Disease Neurodegeneration Protective Factors in Elderly Individuals.

Vemuri P, Knopman DS, Lesnick TG, Przybelski SA, Mielke MM, Graff-Radford J, Murray ME, Roberts RO, Vassilaki M, Lowe VJ, Machulda MM, Jones DT, Petersen RC, Jack CR Jr.

JAMA Neurol. 2017 Jun 1;74(6):718-726. doi: 10.1001/jamaneurol.2017.0244.

38.

Tau aggregation influences cognition and hippocampal atrophy in the absence of beta-amyloid: a clinico-imaging-pathological study of primary age-related tauopathy (PART).

Josephs KA, Murray ME, Tosakulwong N, Whitwell JL, Knopman DS, Machulda MM, Weigand SD, Boeve BF, Kantarci K, Petrucelli L, Lowe VJ, Jack CR Jr, Petersen RC, Parisi JE, Dickson DW.

Acta Neuropathol. 2017 May;133(5):705-715. doi: 10.1007/s00401-017-1681-2. Epub 2017 Feb 3.

PMID:
28160067
39.

Tau-PET uptake: Regional variation in average SUVR and impact of amyloid deposition.

Vemuri P, Lowe VJ, Knopman DS, Senjem ML, Kemp BJ, Schwarz CG, Przybelski SA, Machulda MM, Petersen RC, Jack CR Jr.

Alzheimers Dement (Amst). 2016 Dec 21;6:21-30. doi: 10.1016/j.dadm.2016.12.010. eCollection 2017.

40.

Excessive daytime sleepiness and fatigue may indicate accelerated brain aging in cognitively normal late middle-aged and older adults.

Carvalho DZ, St Louis EK, Boeve BF, Mielke MM, Przybelski SA, Knopman DS, Machulda MM, Roberts RO, Geda YE, Petersen RC, Jack CR Jr, Vemuri P.

Sleep Med. 2017 Apr;32:236-243. doi: 10.1016/j.sleep.2016.08.023. Epub 2016 Nov 3.

41.

Varying Degrees of Temporoparietal Hypometabolism on FDG-PET Reveal Amyloid-Positive Logopenic Primary Progressive Aphasia is not a Homogeneous Clinical Entity.

Krishnan K, Machulda MM, Whitwell JL, Butts AM, Duffy JR, Strand EA, Senjem ML, Spychalla AJ, Jack CR, Lowe VJ, Josephs KA.

J Alzheimers Dis. 2017;55(3):1019-1029.

42.

Defining imaging biomarker cut points for brain aging and Alzheimer's disease.

Jack CR Jr, Wiste HJ, Weigand SD, Therneau TM, Lowe VJ, Knopman DS, Gunter JL, Senjem ML, Jones DT, Kantarci K, Machulda MM, Mielke MM, Roberts RO, Vemuri P, Reyes DA, Petersen RC.

Alzheimers Dement. 2017 Mar;13(3):205-216. doi: 10.1016/j.jalz.2016.08.005. Epub 2016 Sep 30.

43.

Tracking the development of agrammatic aphasia: A tensor-based morphometry study.

Whitwell JL, Duffy JR, Machulda MM, Clark HM, Strand EA, Senjem ML, Gunter JL, Spychalla AJ, Petersen RC, Jack CR Jr, Josephs KA.

Cortex. 2017 May;90:138-148. doi: 10.1016/j.cortex.2016.09.017. Epub 2016 Sep 30.

44.

[Formula: see text]Practice effects and longitudinal cognitive change in clinically normal older adults differ by Alzheimer imaging biomarker status.

Machulda MM, Hagen CE, Wiste HJ, Mielke MM, Knopman DS, Roberts RO, Vemuri P, Lowe VJ, Jack CR Jr, Petersen RC.

Clin Neuropsychol. 2017 Jan;31(1):99-117. doi: 10.1080/13854046.2016.1241303. Epub 2016 Oct 11.

45.

Comparison of Gait Parameters for Predicting Cognitive Decline: The Mayo Clinic Study of Aging.

Savica R, Wennberg AM, Hagen C, Edwards K, Roberts RO, Hollman JH, Knopman DS, Boeve BF, Machulda MM, Petersen RC, Mielke MM.

J Alzheimers Dis. 2017;55(2):559-567.

46.

Mediterranean diet, micronutrients and macronutrients, and MRI measures of cortical thickness.

Staubo SC, Aakre JA, Vemuri P, Syrjanen JA, Mielke MM, Geda YE, Kremers WK, Machulda MM, Knopman DS, Petersen RC, Jack CR Jr, Roberts RO.

Alzheimers Dement. 2017 Feb;13(2):168-177. doi: 10.1016/j.jalz.2016.06.2359. Epub 2016 Jul 25.

47.

Evolution of neurodegeneration-imaging biomarkers from clinically normal to dementia in the Alzheimer disease spectrum.

Knopman DS, Jack CR Jr, Lundt ES, Weigand SD, Vemuri P, Lowe VJ, Kantarci K, Gunter JL, Senjem ML, Mielke MM, Machulda MM, Roberts RO, Boeve BF, Jones DT, Petersen RC.

Neurobiol Aging. 2016 Oct;46:32-42. doi: 10.1016/j.neurobiolaging.2016.06.003. Epub 2016 Jun 16.

48.

FDG-PET and Neuropsychiatric Symptoms among Cognitively Normal Elderly Persons: The Mayo Clinic Study of Aging.

Krell-Roesch J, Ruider H, Lowe VJ, Stokin GB, Pink A, Roberts RO, Mielke MM, Knopman DS, Christianson TJ, Machulda MM, Jack CR, Petersen RC, Geda YE.

J Alzheimers Dis. 2016 Jul 14;53(4):1609-16. doi: 10.3233/JAD-160326.

49.

Levels of tau protein in plasma are associated with neurodegeneration and cognitive function in a population-based elderly cohort.

Dage JL, Wennberg AMV, Airey DC, Hagen CE, Knopman DS, Machulda MM, Roberts RO, Jack CR Jr, Petersen RC, Mielke MM.

Alzheimers Dement. 2016 Dec;12(12):1226-1234. doi: 10.1016/j.jalz.2016.06.001. Epub 2016 Jul 18.

50.

Age and neurodegeneration imaging biomarkers in persons with Alzheimer disease dementia.

Knopman DS, Jack CR Jr, Wiste HJ, Weigand SD, Vemuri P, Lowe VJ, Kantarci K, Gunter JL, Senjem ML, Mielke MM, Machulda MM, Roberts RO, Boeve BF, Jones DT, Petersen RC.

Neurology. 2016 Aug 16;87(7):691-8. doi: 10.1212/WNL.0000000000002979. Epub 2016 Jul 15.

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