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Items: 28

1.

Identification of the human liver cytochrome P450 enzymes involved in the in vitro metabolism of a novel 5-lipoxygenase inhibitor.

Machinist JM, Mayer MD, Roberts EM, Surber BW, Rodrigues AD.

Drug Metab Dispos. 1998 Oct;26(10):970-6.

PMID:
9763401
2.

Pharmacokinetics of zileuton and its metabolites in patients with renal impairment.

Awni WM, Wong S, Chu SY, Patterson K, Hansen R, Machinist JM, Drajesk J, Keane WF, Halstenson CE.

J Clin Pharmacol. 1997 May;37(5):395-404.

PMID:
9156372
3.

Lansoprazole pharmacokinetics in subjects with various degrees of kidney function.

Karol MD, Machinist JM, Cavanaugh JM.

Clin Pharmacol Ther. 1997 Apr;61(4):450-8.

PMID:
9129562
4.
5.

Identification of the human liver cytochrome P450 enzymes involved in the metabolism of zileuton (ABT-077) and its N-dehydroxylated metabolite, Abbott-66193.

Machinist JM, Mayer MD, Shet MS, Ferrero JL, Rodrigues AD.

Drug Metab Dispos. 1995 Oct;23(10):1163-74.

PMID:
8654206
6.

Pharmacokinetics of lansoprazole in hemodialysis patients.

Karol MD, Machinist JM, Cavanaugh JM.

J Clin Pharmacol. 1995 Aug;35(8):815-20.

PMID:
8522639
7.

The effect of mild or moderate hepatic impairment (cirrhosis) on the pharmacokinetics of zileuton.

Awni WM, Cavanaugh JH, Braeckman RA, Chu SY, Patterson KJ, Machinist JM, Granneman GR.

Clin Pharmacokinet. 1995;29 Suppl 2:49-61.

PMID:
8620671
8.

The pharmacokinetics of zileuton in healthy young and elderly volunteers.

Braeckman RA, Granneman GR, Locke CS, Machinist JM, Cavannaugh JH, Awni WM.

Clin Pharmacokinet. 1995;29 Suppl 2:42-8.

PMID:
8620670
9.

In vitro plasma protein binding of zileuton and its N-dehydroxylated metabolite.

Machinist JM, Kukulka MJ, Bopp BA.

Clin Pharmacokinet. 1995;29 Suppl 2:34-41.

PMID:
8620669
10.

The in vitro hepatic metabolism of ABT-418, a cholinergic channel activator, in rats, dogs, cynomolgus monkeys, and humans.

Rodrigues AD, Ferrero JL, Amann MT, Rotert GA, Cepa SP, Surber BW, Machinist JM, Tich NR, Sullivan JP, Garvey DS, et al.

Drug Metab Dispos. 1994 Sep-Oct;22(5):788-98.

PMID:
7530622
11.

Measurement of liver microsomal cytochrome p450 (CYP2D6) activity using [O-methyl-14C]dextromethorphan.

Rodrigues AD, Kukulka MJ, Surber BW, Thomas SB, Uchic JT, Rotert GA, Michel G, Thome-Kromer B, Machinist JM.

Anal Biochem. 1994 Jun;219(2):309-20.

PMID:
8080088
12.

Metabolism of 14C-estazolam in dogs and humans.

Machinist JM, Bopp BA, Anderson DJ, Granneman GR, Sonders RC, Tolman K, Buchi K, Rollins D.

Xenobiotica. 1986 Jan;16(1):11-20.

PMID:
2868576
13.

The hepatotoxicity of valproic acid and its metabolites in rats. II. Intermediary and valproic acid metabolism.

Granneman GR, Wang SI, Kesterson JW, Machinist JM.

Hepatology. 1984 Nov-Dec;4(6):1153-8.

PMID:
6437961
14.

The hepatotoxicity of valproic acid and its metabolites in rats. I. Toxicologic, biochemical and histopathologic studies.

Kesterson JW, Granneman GR, Machinist JM.

Hepatology. 1984 Nov-Dec;4(6):1143-52.

PMID:
6437960
15.

Metabolism of [14C]Cefmenoxime in normal subjects after intramuscular administration.

Machinist JM, Bopp BA, Quinn D.

Antimicrob Agents Chemother. 1984 Oct;26(4):431-5.

16.

Aspects of the metabolism of valproic acid.

Granneman GR, Wang SI, Machinist JM, Kesterson JW.

Xenobiotica. 1984 May;14(5):375-87.

PMID:
6433565
17.

Effect of SKF 525-A on the excretion of amine oxides by the rat.

Dehner EW, Machinist JM, Ziegler DM.

Life Sci. 1968 Nov 1;7(21):1135-46. No abstract available.

PMID:
5712725
18.

Glycolytic and respiratory properties of intact mammalian cells: inhibitor studies.

Gregg CT, Machinist JM, Currie WD.

Arch Biochem Biophys. 1968 Sep 20;127(1):101-11. No abstract available.

PMID:
5681414
19.

Microsomal oxidases. 3. Comparison of species and organ distribution of dialkylarylamine N-oxide dealkylase and dialkylarylamine N-oxidase.

Machinist JM, Dehner EW, Ziegler DM.

Arch Biochem Biophys. 1968 Jun;125(3):858-64. No abstract available.

PMID:
5671048
20.

Microsomal oxidases. II. Properties of a pork liver microsomal N-oxide dealkylase.

Machinist JM, Orme-Johnson WH, Ziegler DM.

Biochemistry. 1966 Sep;5(9):2939-43. No abstract available.

PMID:
5961882
21.
22.
24.

TETRACHLOROHYDROQUINONE OXIDASE ACTIVITY IN BEEF HEART MITOCHONDRIA.

MACHINIST JM, CRANE FL, JACOBS EE.

J Biol Chem. 1965 Apr;240:1788-95. No abstract available.

25.

REACTIONS OF COENZYME Q IN THE DPNH DEHYDROGENASE SEGMENT OF THE RESPIRATORY CHAIN.

MACHINIST JM, SINGER TP.

Proc Natl Acad Sci U S A. 1965 Feb;53:467-74. No abstract available.

26.

Proteolipids. 3. Protection of lipid-cytochrome c by an antioxidant fraction from beef heart.

Das ML, Crane FL, Machinist JM.

Biochem Biophys Res Commun. 1964 Nov 30;17(5):593-6. No abstract available.

PMID:
4285953
27.

The proteolipids of cytochrome c.

DAS ML, HIRATSUKA H, MACHINIST JM, CRANE FL.

Biochim Biophys Acta. 1962 Jul 2;60:433-4. No abstract available.

PMID:
13883623
28.

A negatively charged pore in the mitochondrial membrane as a site for cytochrome c function.

MACHINIST JM, DAS ML, CRANE FL, JACOBS EE.

Biochem Biophys Res Commun. 1962 Jan 24;6:475-8. No abstract available.

PMID:
14467888

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