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Items: 7

1.

Simulating the Impact of Elevated Levels of Interleukin-6 on the Pharmacokinetics of Various CYP450 Substrates in Patients with Neuromyelitis Optica or Neuromyelitis Optica Spectrum Disorders in Different Ethnic Populations.

Machavaram KK, Endo-Tsukude C, Terao K, Gill KL, Hatley OJ, Gardner I, Parrott N, Ducray PS.

AAPS J. 2019 Mar 18;21(3):42. doi: 10.1208/s12248-019-0309-y.

PMID:
30887238
2.

Potential Sources of Inter-Subject Variability in Monoclonal Antibody Pharmacokinetics.

Gill KL, Machavaram KK, Rose RH, Chetty M.

Clin Pharmacokinet. 2016 Jul;55(7):789-805. doi: 10.1007/s40262-015-0361-4. Review.

PMID:
26818483
3.
4.

A physiologically based pharmacokinetic modeling approach to predict disease-drug interactions: suppression of CYP3A by IL-6.

Machavaram KK, Almond LM, Rostami-Hodjegan A, Gardner I, Jamei M, Tay S, Wong S, Joshi A, Kenny JR.

Clin Pharmacol Ther. 2013 Aug;94(2):260-8. doi: 10.1038/clpt.2013.79. Epub 2013 Apr 10.

PMID:
23588308
5.

Lymphatic absorption of subcutaneously administered proteins: influence of different injection sites on the absorption of darbepoetin alfa using a sheep model.

Kota J, Machavaram KK, McLennan DN, Edwards GA, Porter CJ, Charman SA.

Drug Metab Dispos. 2007 Dec;35(12):2211-7. Epub 2007 Sep 17.

PMID:
17875672
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