Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 50 of 71

1.

What Is the Role of the New Index Relative Fat Mass (RFM) in the Assessment of Nonalcoholic Fatty Liver Disease (NAFLD)?

Machado MV, Policarpo S, Coutinho J, Carvalhana S, Leitão J, Carvalho A, Silva AP, Velasco F, Medeiros I, Alves AC, Bourbon M, Cortez-Pinto H.

Obes Surg. 2020 Feb;30(2):560-568. doi: 10.1007/s11695-019-04213-8.

PMID:
31637670
2.

Exercise-induced cardiac opioid system activation attenuates apoptosis pathway in obese rats.

Alexandre-Santos B, Machado MV, Menezes AC, Velasco LL, Sepúlveda-Fragoso V, Vieira AB, Borges JP, Tibiriçá E, Magliano DC, Nóbrega ACLD, Frantz EDC.

Life Sci. 2019 Aug 15;231:116542. doi: 10.1016/j.lfs.2019.06.017. Epub 2019 Jun 6.

PMID:
31176781
3.

Skeletal muscle miR-34a/SIRT1:AMPK axis is activated in experimental and human non-alcoholic steatohepatitis.

Simão AL, Afonso MB, Rodrigues PM, Gama-Carvalho M, Machado MV, Cortez-Pinto H, Rodrigues CMP, Castro RE.

J Mol Med (Berl). 2019 Aug;97(8):1113-1126. doi: 10.1007/s00109-019-01796-8. Epub 2019 May 28.

PMID:
31139863
4.

I1-imidazoline receptor-mediated cardiovascular and metabolic effects in high-fat diet-induced metabolic syndrome in rats.

Nascimento AR, Gomes F, Machado MV, Gonçalves-de-Albuquerque C, Bousquet P, Tibiriçá E.

Auton Neurosci. 2019 Mar;217:18-25. doi: 10.1016/j.autneu.2018.12.007. Epub 2018 Dec 22.

PMID:
30704971
5.

Potassium permanganate - an odd cause of caustic injury.

Carvalho JR, Machado MV, Carrilho-Ribeiro L, Marinho RT.

Clin Res Hepatol Gastroenterol. 2019 Jun;43(3):230-231. doi: 10.1016/j.clinre.2018.10.016. Epub 2018 Nov 22. No abstract available.

PMID:
30472181
6.

Clinical relevance of liver histopathology and different histological classifications of NASH in adults.

Nascimbeni F, Ballestri S, Machado MV, Mantovani A, Cortez-Pinto H, Targher G, Lonardo A.

Expert Rev Gastroenterol Hepatol. 2018 Apr;12(4):351-367. doi: 10.1080/17474124.2018.1415756. Epub 2017 Dec 26. Review.

PMID:
29224471
7.

Hedgehog signalling in liver pathophysiology.

Machado MV, Diehl AM.

J Hepatol. 2018 Mar;68(3):550-562. doi: 10.1016/j.jhep.2017.10.017. Epub 2017 Oct 26. Review.

8.

Exercise training dose differentially alters muscle and heart capillary density and metabolic functions in an obese rat with metabolic syndrome.

Machado MV, Vieira AB, da Conceição FG, Nascimento AR, da Nóbrega ACL, Tibirica E.

Exp Physiol. 2017 Dec 1;102(12):1716-1728. doi: 10.1113/EP086416. Epub 2017 Oct 26.

9.

High, but not low, exercise volume shifts the balance of renin-angiotensin system toward ACE2/Mas receptor axis in skeletal muscle in obese rats.

Frantz EDC, Giori IG, Machado MV, Magliano DC, Freitas FM, Andrade MSB, Vieira AB, Nóbrega ACL, Tibiriçá E.

Am J Physiol Endocrinol Metab. 2017 Oct 1;313(4):E473-E482. doi: 10.1152/ajpendo.00078.2017. Epub 2017 Jul 5.

10.

miR-21 ablation and obeticholic acid ameliorate nonalcoholic steatohepatitis in mice.

Rodrigues PM, Afonso MB, Simão AL, Carvalho CC, Trindade A, Duarte A, Borralho PM, Machado MV, Cortez-Pinto H, Rodrigues CM, Castro RE.

Cell Death Dis. 2017 May 25;8(5):e2825. doi: 10.1038/cddis.2017.246.

11.

Loss of pericyte smoothened activity in mice with genetic deficiency of leptin.

Xie G, Swiderska-Syn M, Jewell ML, Machado MV, Michelotti GA, Premont RT, Diehl AM.

BMC Cell Biol. 2017 Apr 20;18(1):20. doi: 10.1186/s12860-017-0135-y.

12.

miR-21 ablation and obeticholic acid ameliorate nonalcoholic steatohepatitis in mice.

Rodrigues PM, Afonso MB, Simão AL, Carvalho CC, Trindade A, Duarte A, Borralho PM, Machado MV, Cortez-Pinto H, Rodrigues CM, Castro RE.

Cell Death Dis. 2017 Apr 13;8(4):e2748. doi: 10.1038/cddis.2017.172.

13.

Obesity paradox in cirrhosis: is it real or just an illusion?

Machado MV, Cortez-Pinto H.

Liver Int. 2016 Oct;36(10):1412-4. doi: 10.1111/liv.13154. No abstract available.

PMID:
27616334
14.

A Bugs Battle on Behalf of the Liver.

Machado MV.

GE Port J Gastroenterol. 2016 May 8;23(3):126-129. doi: 10.1016/j.jpge.2016.03.004. eCollection 2016 May-Jun. No abstract available.

15.

Central Sympathetic Modulation Reverses Microvascular Alterations in a Rat Model of High-Fat Diet-Induced Metabolic Syndrome.

Nascimento AR, Machado MV, Gomes F, Vieira AB, Gonçalves-de-Albuquerque CF, Lessa MA, Bousquet P, Tibiriçá E.

Microcirculation. 2016 May;23(4):320-9. doi: 10.1111/micc.12280.

PMID:
27086551
16.

Diet, Microbiota, Obesity, and NAFLD: A Dangerous Quartet.

Machado MV, Cortez-Pinto H.

Int J Mol Sci. 2016 Apr 1;17(4):481. doi: 10.3390/ijms17040481. Review.

17.

Exercise Training Reverses Structural Microvascular Rarefaction and Improves Endothelium-Dependent Microvascular Reactivity in Rats with Diabetes.

Machado MV, Martins RL, Borges J, Antunes BR, Estato V, Vieira AB, Tibiriçá E.

Metab Syndr Relat Disord. 2016 Aug;14(6):298-304. doi: 10.1089/met.2015.0146. Epub 2016 Mar 22.

PMID:
27003580
18.

Pathogenesis of Nonalcoholic Steatohepatitis.

Machado MV, Diehl AM.

Gastroenterology. 2016 Jun;150(8):1769-77. doi: 10.1053/j.gastro.2016.02.066. Epub 2016 Feb 27. Review.

19.

Caspase-2 promotes obesity, the metabolic syndrome and nonalcoholic fatty liver disease.

Machado MV, Michelotti GA, Jewell ML, Pereira TA, Xie G, Premont RT, Diehl AM.

Cell Death Dis. 2016 Feb 18;7:e2096. doi: 10.1038/cddis.2016.19.

20.

Epidemiological modifiers of non-alcoholic fatty liver disease: Focus on high-risk groups.

Non-alcoholic Fatty Liver Disease Study Group, Lonardo A, Bellentani S, Argo CK, Ballestri S, Byrne CD, Caldwell SH, Cortez-Pinto H, Grieco A, Machado MV, Miele L, Targher G.

Dig Liver Dis. 2015 Dec;47(12):997-1006. doi: 10.1016/j.dld.2015.08.004. Epub 2015 Aug 14. Review.

PMID:
26454786
21.

Vitamin B5 and N-Acetylcysteine in Nonalcoholic Steatohepatitis: A Preclinical Study in a Dietary Mouse Model.

Machado MV, Kruger L, Jewell ML, Michelotti GA, Pereira Tde A, Xie G, Moylan CA, Diehl AM.

Dig Dis Sci. 2016 Jan;61(1):137-48. doi: 10.1007/s10620-015-3871-x. Epub 2015 Sep 24.

22.

Schistosome-induced cholangiocyte proliferation and osteopontin secretion correlate with fibrosis and portal hypertension in human and murine schistosomiasis mansoni.

Pereira TA, Syn WK, Machado MV, Vidigal PV, Resende V, Voieta I, Xie G, Otoni A, Souza MM, Santos ET, Chan IS, Trindade GV, Choi SS, Witek RP, Pereira FE, Secor WE, Andrade ZA, Lambertucci JR, Diehl AM.

Clin Sci (Lond). 2015 Nov;129(10):875-83. doi: 10.1042/CS20150117. Epub 2015 Jul 21.

23.

Proangiogenic factors in the development of HCC in alcoholic cirrhosis.

Machado MV, Cortez-Pinto H.

Clin Res Hepatol Gastroenterol. 2015 Sep;39 Suppl 1:S104-8. doi: 10.1016/j.clinre.2015.06.001. Epub 2015 Jul 17. Review.

PMID:
26193870
24.

Correction: Mouse Models of Diet-Induced Nonalcoholic Steatohepatitis Reproduce the Heterogeneity of the Human Disease.

Machado MV, Michelotti GA, Xie G, de Almeida TP, Boursier J, Bohnic B, Guy CD, Diehl AM.

PLoS One. 2015 Jun 29;10(6):e0132315. doi: 10.1371/journal.pone.0132315. eCollection 2015. No abstract available.

25.

Accumulation of duct cells with activated YAP parallels fibrosis progression in non-alcoholic fatty liver disease.

Machado MV, Michelotti GA, Pereira TA, Xie G, Premont R, Cortez-Pinto H, Diehl AM.

J Hepatol. 2015 Oct;63(4):962-70. doi: 10.1016/j.jhep.2015.05.031. Epub 2015 Jun 10.

26.

Genetic ancestry analysis in non-alcoholic fatty liver disease patients from Brazil and Portugal.

Cavalcante LN, Stefano JT, Machado MV, Mazo DF, Rabelo F, Sandes KA, Carrilho FJ, Cortez-Pinto H, Lyra AC, de Oliveira CP.

World J Hepatol. 2015 Jun 8;7(10):1433-8. doi: 10.4254/wjh.v7.i10.1433.

27.

Mouse models of diet-induced nonalcoholic steatohepatitis reproduce the heterogeneity of the human disease.

Machado MV, Michelotti GA, Xie G, Almeida Pereira T, Boursier J, Bohnic B, Guy CD, Diehl AM.

PLoS One. 2015 May 27;10(5):e0127991. doi: 10.1371/journal.pone.0127991. eCollection 2015. Erratum in: PLoS One. 2015;10(6):e0132315. de Almeida, Thiago Pereira [corrected to Almeida Pereira, Thiago].

28.

Fibrosis in nonalcoholic Fatty liver disease: mechanisms and clinical implications.

Angulo P, Machado MV, Diehl AM.

Semin Liver Dis. 2015 May;35(2):132-45. doi: 10.1055/s-0035-1550065. Epub 2015 May 14. Review.

PMID:
25974899
29.

Pleiotrophin regulates the ductular reaction by controlling the migration of cells in liver progenitor niches.

Michelotti GA, Tucker A, Swiderska-Syn M, Machado MV, Choi SS, Kruger L, Soderblom E, Thompson JW, Mayer-Salman M, Himburg HA, Moylan CA, Guy CD, Garman KS, Premont RT, Chute JP, Diehl AM.

Gut. 2016 Apr;65(4):683-92. doi: 10.1136/gutjnl-2014-308176. Epub 2015 Jan 16.

30.

Role of Fn14 in acute alcoholic steatohepatitis in mice.

Karaca G, Xie G, Moylan C, Swiderska-Syn M, Guy CD, Krüger L, Machado MV, Choi SS, Michelotti GA, Burkly LC, Diehl AM.

Am J Physiol Gastrointest Liver Physiol. 2015 Feb 15;308(4):G325-34. doi: 10.1152/ajpgi.00429.2013. Epub 2014 Dec 18.

31.

Non-alcoholic fatty liver disease: what the clinician needs to know.

Machado MV, Cortez-Pinto H.

World J Gastroenterol. 2014 Sep 28;20(36):12956-80. doi: 10.3748/wjg.v20.i36.12956. Review.

32.

Physical exercise restores microvascular function in obese rats with metabolic syndrome.

Machado MV, Vieira AB, Nascimento AR, Martins RL, Daleprane JB, Lessa MA, Tibiriçá E.

Metab Syndr Relat Disord. 2014 Nov;12(9):484-92. doi: 10.1089/met.2014.0040. Epub 2014 Aug 19.

PMID:
25137183
33.

Reduced lipoapoptosis, hedgehog pathway activation and fibrosis in caspase-2 deficient mice with non-alcoholic steatohepatitis.

Machado MV, Michelotti GA, Pereira Tde A, Boursier J, Kruger L, Swiderska-Syn M, Karaca G, Xie G, Guy CD, Bohinc B, Lindblom KR, Johnson E, Kornbluth S, Diehl AM.

Gut. 2015 Jul;64(7):1148-57. doi: 10.1136/gutjnl-2014-307362. Epub 2014 Jul 22.

34.

Nuclear receptors: how do they position in non-alcoholic fatty liver disease treatment?

Machado MV, Cortez-Pinto H.

Liver Int. 2014 Oct;34(9):1291-4. doi: 10.1111/liv.12578. No abstract available.

PMID:
24766162
35.

Management of fatty liver disease with the metabolic syndrome.

Machado MV, Cortez-Pinto H.

Expert Rev Gastroenterol Hepatol. 2014 Jul;8(5):487-500. doi: 10.1586/17474124.2014.903798. Epub 2014 Mar 26. Review.

PMID:
24665862
36.

Genetic polymorphisms of proangiogenic factors seem to favor hepatocellular carcinoma development in alcoholic cirrhosis.

Machado MV, Janeiro A, Miltenberger-Miltenyi G, Cortez-Pinto H.

Eur J Gastroenterol Hepatol. 2014 Apr;26(4):438-43. doi: 10.1097/MEG.0000000000000044.

PMID:
24445728
37.

TWEAK/Fn14 signaling is required for liver regeneration after partial hepatectomy in mice.

Karaca G, Swiderska-Syn M, Xie G, Syn WK, Krüger L, Machado MV, Garman K, Choi SS, Michelotti GA, Burkly LC, Ochoa B, Diehl AM.

PLoS One. 2014 Jan 9;9(1):e83987. doi: 10.1371/journal.pone.0083987. eCollection 2014.

38.

Liver renewal: detecting misrepair and optimizing regeneration.

Machado MV, Diehl AM.

Mayo Clin Proc. 2014 Jan;89(1):120-30. doi: 10.1016/j.mayocp.2013.10.009.

PMID:
24388030
39.

Myofibroblastic cells function as progenitors to regenerate murine livers after partial hepatectomy.

Swiderska-Syn M, Syn WK, Xie G, Krüger L, Machado MV, Karaca G, Michelotti GA, Choi SS, Premont RT, Diehl AM.

Gut. 2014 Aug;63(8):1333-44. doi: 10.1136/gutjnl-2013-305962. Epub 2013 Oct 30.

40.

Alcohol activates the hedgehog pathway and induces related procarcinogenic processes in the alcohol-preferring rat model of hepatocarcinogenesis.

Chan IS, Guy CD, Machado MV, Wank A, Kadiyala V, Michelotti G, Choi S, Swiderska-Syn M, Karaca G, Pereira TA, Yip-Schneider MT, Max Schmidt C, Diehl AM.

Alcohol Clin Exp Res. 2014 Mar;38(3):787-800. doi: 10.1111/acer.12279. Epub 2013 Oct 24.

41.

NAFLD, NASH and liver cancer.

Michelotti GA, Machado MV, Diehl AM.

Nat Rev Gastroenterol Hepatol. 2013 Nov;10(11):656-65. doi: 10.1038/nrgastro.2013.183. Epub 2013 Oct 1. Review.

PMID:
24080776
42.

Leptin in the treatment of lipodystrophy-associated nonalcoholic fatty liver disease: are we there already?

Machado MV, Cortez-Pinto H.

Expert Rev Gastroenterol Hepatol. 2013 Aug;7(6):513-5. doi: 10.1586/17474124.2013.814903.

PMID:
23985000
43.

The benefits of restraint: a pivotal role for IL-13 in hepatic glucose homeostasis.

Machado MV, Yang Y, Diehl AM.

J Clin Invest. 2013 Jan;123(1):115-7. doi: 10.1172/JCI67238. Epub 2012 Dec 21.

44.

Non-invasive diagnosis of non-alcoholic fatty liver disease. A critical appraisal.

Machado MV, Cortez-Pinto H.

J Hepatol. 2013 May;58(5):1007-19. doi: 10.1016/j.jhep.2012.11.021. Epub 2012 Nov 23. Review.

45.

miR-34a/SIRT1/p53 is suppressed by ursodeoxycholic acid in the rat liver and activated by disease severity in human non-alcoholic fatty liver disease.

Castro RE, Ferreira DM, Afonso MB, Borralho PM, Machado MV, Cortez-Pinto H, Rodrigues CM.

J Hepatol. 2013 Jan;58(1):119-25. doi: 10.1016/j.jhep.2012.08.008. Epub 2012 Aug 15.

PMID:
22902550
46.

Improving dietary patterns in patients with nonalcoholic fatty liver disease.

Carvalhana S, Machado MV, Cortez-Pinto H.

Curr Opin Clin Nutr Metab Care. 2012 Sep;15(5):468-73. doi: 10.1097/MCO.0b013e3283566614. Review.

PMID:
22878240
47.

How adiponectin, leptin, and ghrelin orchestrate together and correlate with the severity of nonalcoholic fatty liver disease.

Machado MV, Coutinho J, Carepa F, Costa A, Proença H, Cortez-Pinto H.

Eur J Gastroenterol Hepatol. 2012 Oct;24(10):1166-72. doi: 10.1097/MEG.0b013e32835609b0.

PMID:
22735605
48.

 Gut microbiota and nonalcoholic fatty liver disease.

Machado MV, Cortez-Pinto H.

Ann Hepatol. 2012 Jul-Aug;11(4):440-9. Review.

49.

[Intra-gastric ballon in the treatment of morbid obesity].

Carvalho MR, Jorge Z, Nobre E, Dias T, Cortez-Pinto H, Machado MV, Camolas J, Neves S, Guerra A, Vieira J, Fagundes MJ, Brito MJ, Almeida Nunes P, do Carmo I.

Acta Med Port. 2011 Jul-Aug;24(4):489-98. Epub 2011 Dec 12. Portuguese.

50.

NKT cells and the hedgehog pathway: an unhealthy marriage in non-alcoholic fatty liver disease?

Machado MV, Cortez-Pinto H.

Gut. 2012 Sep;61(9):1244-5. doi: 10.1136/gutjnl-2012-302378. Epub 2012 Apr 5. Review. No abstract available.

PMID:
22490528

Supplemental Content

Loading ...
Support Center