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Items: 1 to 50 of 107

1.

Folic acid supplementation reduces multigenerational sperm miRNA perturbation induced by in utero environmental contaminant exposure.

Herst PM, Dalvai M, Lessard M, Charest PL, Navarro P, Joly-Beauparlant C, Droit A, Trasler JM, Kimmins S, MacFarlane AJ, Benoit-Biancamano MO, Bailey JL.

Environ Epigenet. 2019 Dec 14;5(4):dvz024. doi: 10.1093/eep/dvz024. eCollection 2019 Oct.

2.

Prenatal Exposure to Environmentally-Relevant Contaminants Perturbs Male Reproductive Parameters Across Multiple Generations that are Partially Protected by Folic Acid Supplementation.

Lessard M, Herst PM, Charest PL, Navarro P, Joly-Beauparlant C, Droit A, Kimmins S, Trasler J, Benoit-Biancamano MO, MacFarlane AJ, Dalvai M, Bailey JL.

Sci Rep. 2019 Sep 25;9(1):13829. doi: 10.1038/s41598-019-50060-z.

3.

Maternal folic acid supplementation does not counteract the deleterious impact of prenatal exposure to environmental pollutants on lipid homeostasis in male rat descendants.

Navarro P, Dalvai M, Charest PL, Herst PM, Lessard M, Marcotte B, Mitchell PL, Leblanc N, Kimmins S, Trasler J, MacFarlane AJ, Marette A, Bailey JL, Jacques H.

J Dev Orig Health Dis. 2019 Sep 16:1-11. doi: 10.1017/S2040174419000497. [Epub ahead of print]

PMID:
31525320
4.

The Buffalo Concussion Bike Test for Concussion Assessment in Adolescents.

Haider MN, Johnson SL, Mannix R, Macfarlane AJ, Constantino D, Johnson BD, Willer B, Leddy J.

Sports Health. 2019 Nov/Dec;11(6):492-497. doi: 10.1177/1941738119870189. Epub 2019 Sep 5.

PMID:
31486715
5.

Regional anesthesia for vascular surgery: does the anesthetic choice influence outcome?

Macfarlane AJR, Vlassakov K, Elkassabany N.

Curr Opin Anaesthesiol. 2019 Oct;32(5):690-696. doi: 10.1097/ACO.0000000000000781. Review.

PMID:
31415047
6.

The MTHFR 677C>T polymorphism is associated with unmetabolized folic acid in breast milk in a cohort of Canadian women.

Page R, Wong A, Arbuckle TE, MacFarlane AJ.

Am J Clin Nutr. 2019 Aug 1;110(2):401-409. doi: 10.1093/ajcn/nqz056.

PMID:
31005971
7.

Moderate maternal folic acid supplementation ameliorates adverse embryonic and epigenetic outcomes associated with assisted reproduction in a mouse model.

Rahimi S, Martel J, Karahan G, Angle C, Behan NA, Chan D, MacFarlane AJ, Trasler JM.

Hum Reprod. 2019 May 1;34(5):851-862. doi: 10.1093/humrep/dez036.

PMID:
30989206
8.

Association of maternal risk factors with the recent rise of neural tube defects in Canada.

Liu S, Evans J, MacFarlane AJ, Ananth CV, Little J, Kramer MS, Joseph KS.

Paediatr Perinat Epidemiol. 2019 Mar;33(2):145-153. doi: 10.1111/ppe.12543.

PMID:
30920008
9.

The role of maternal homocysteine concentration in placenta-mediated complications: findings from the Ottawa and Kingston birth cohort.

Chaudhry SH, Taljaard M, MacFarlane AJ, Gaudet LM, Smith GN, Rodger M, Rennicks White R, Walker MC, Wen SW.

BMC Pregnancy Childbirth. 2019 Feb 19;19(1):75. doi: 10.1186/s12884-019-2219-5.

10.

A report of activities related to the Dietary Reference Intakes from the Joint Canada-US Dietary Reference Intakes Working Group.

MacFarlane AJ, Cogswell ME, de Jesus JM, Greene-Finestone LS, Klurfeld DM, Lynch CJ, Regan K, Yamini S; Joint Canada-US Dietary Reference Intakes Working Group.

Am J Clin Nutr. 2019 Feb 1;109(2):251-259. doi: 10.1093/ajcn/nqy293.

11.

Prevalence rates of spina bifida in Alberta, Canada: 2001-2015. Can we achieve more prevention?

Lowry RB, Bedard T, MacFarlane AJ, Crawford S, Sibbald B, Agborsangaya BC.

Birth Defects Res. 2019 Feb 1;111(3):151-158. doi: 10.1002/bdr2.1438. Epub 2018 Dec 18. Review.

PMID:
30561844
12.
13.

A genetic deficiency in folic acid metabolism impairs recovery after ischemic stroke.

Jadavji NM, Emmerson JT, Shanmugalingam U, MacFarlane AJ, Willmore WG, Smith PD.

Exp Neurol. 2018 Nov;309:14-22. doi: 10.1016/j.expneurol.2018.07.014. Epub 2018 Jul 25.

PMID:
30055159
14.

A systematic review of mechanical thromboprophylaxis in the lithotomy position.

Gelder C, McCallum AL, Macfarlane AJR, Anderson JH.

Surgeon. 2018 Dec;16(6):365-371. doi: 10.1016/j.surge.2018.03.005. Epub 2018 Apr 23.

PMID:
29699782
15.

Folate deficiency increases chromosomal damage and mutations in hematopoietic cells in the transgenic mutamouse model.

LeBlanc DP, Behan NA, O'Brien JM, Marchetti F, MacFarlane AJ.

Environ Mol Mutagen. 2018 Jun;59(5):366-374. doi: 10.1002/em.22190. Epub 2018 Apr 18.

PMID:
29668043
16.

Intergenerational impact of paternal lifetime exposures to both folic acid deficiency and supplementation on reproductive outcomes and imprinted gene methylation.

Ly L, Chan D, Aarabi M, Landry M, Behan NA, MacFarlane AJ, Trasler J.

Mol Hum Reprod. 2017 Jul 1;23(7):461-477. doi: 10.1093/molehr/gax029.

17.

B-vitamin and choline supplementation increases neuroplasticity and recovery after stroke.

Jadavji NM, Emmerson JT, MacFarlane AJ, Willmore WG, Smith PD.

Neurobiol Dis. 2017 Jul;103:89-100. doi: 10.1016/j.nbd.2017.04.001. Epub 2017 Apr 7.

PMID:
28396257
18.

Total folate and unmetabolized folic acid in the breast milk of a cross-section of Canadian women.

Page R, Robichaud A, Arbuckle TE, Fraser WD, MacFarlane AJ.

Am J Clin Nutr. 2017 May;105(5):1101-1109. doi: 10.3945/ajcn.116.137968. Epub 2017 Mar 15.

PMID:
28298392
19.

The economic costs of intrapartum care in Tower Hamlets: A comparison between the cost of birth in a freestanding midwifery unit and hospital for women at low risk of obstetric complications.

Schroeder L, Patel N, Keeler M, Rocca-Ihenacho L, Macfarlane AJ.

Midwifery. 2017 Feb;45:28-35. doi: 10.1016/j.midw.2016.11.006. Epub 2016 Nov 21.

PMID:
27984773
20.

Options for basing Dietary Reference Intakes (DRIs) on chronic disease endpoints: report from a joint US-/Canadian-sponsored working group.

Yetley EA, MacFarlane AJ, Greene-Finestone LS, Garza C, Ard JD, Atkinson SA, Bier DM, Carriquiry AL, Harlan WR, Hattis D, King JC, Krewski D, O'Connor DL, Prentice RL, Rodricks JV, Wells GA.

Am J Clin Nutr. 2017 Jan;105(1):249S-285S. doi: 10.3945/ajcn.116.139097. Epub 2016 Dec 7. Review.

21.

Authors' reply re: Wide differences in mode of delivery within Europe: risk-stratified analyses of aggregated routine data from the Euro-Peristat study.

Macfarlane AJ, Blondel B, Mohangoo AD, Cuttini M, Nijhuis J, Novak Z, Ólafsdóttir HS, Zeitlin J; Euro-Peristat Scientific Committee.

BJOG. 2016 Dec;123(13):2231. doi: 10.1111/1471-0528.14140. No abstract available.

22.

Consent for anaesthesia-sleepwalking into trouble.

Basler MH, Macfarlane AJ, McKinlay S.

BMJ. 2016 Nov 21;355:i6189. doi: 10.1136/bmj.i6189. No abstract available.

PMID:
27872038
23.

The elephant in the room: using nutritional biomarker cutoffs to assess status.

MacFarlane AJ.

Am J Clin Nutr. 2016 Dec;104(6):1493-1494. Epub 2016 Nov 16. No abstract available.

PMID:
27852612
24.

Murine MTHFD1-synthetase deficiency, a model for the human MTHFD1 R653Q polymorphism, decreases growth of colorectal tumors.

Lévesque N, Christensen KE, Van Der Kraak L, Best AF, Deng L, Caldwell D, MacFarlane AJ, Beauchemin N, Rozen R.

Mol Carcinog. 2017 Mar;56(3):1030-1040. doi: 10.1002/mc.22568. Epub 2016 Nov 1.

PMID:
27597531
25.

Serum and red-blood-cell folate demonstrate differential associations with BMI in pregnant women.

Shen M, Chaudhry SH, MacFarlane AJ, Gaudet L, Smith GN, Rodger M, White RR, Walker MC, Wen SW.

Public Health Nutr. 2016 Oct;19(14):2572-9. doi: 10.1017/S1368980016000756. Epub 2016 Apr 18.

PMID:
27087411
26.

Linking databases on perinatal health: a review of the literature and current practices in Europe.

Delnord M, Szamotulska K, Hindori-Mohangoo AD, Blondel B, Macfarlane AJ, Dattani N, Barona C, Berrut S, Zile I, Wood R, Sakkeus L, Gissler M, Zeitlin J; Euro-Peristat Scientific Committee.

Eur J Public Health. 2016 Jun;26(3):422-30. doi: 10.1093/eurpub/ckv231. Epub 2016 Jan 10. Review.

27.

Effect of folic acid on human trophoblast health and function in vitro.

Ahmed T, Fellus I, Gaudet J, MacFarlane AJ, Fontaine-Bisson B, Bainbridge SA.

Placenta. 2016 Jan;37:7-15. doi: 10.1016/j.placenta.2015.11.012. Epub 2015 Nov 27.

PMID:
26748157
28.

Modeling Demonstrates That Folic Acid Fortification of Whole-Wheat Flour Could Reduce the Prevalence of Folate Inadequacy in Canadian Whole-Wheat Consumers.

Chan YM, MacFarlane AJ, O'Connor DL.

J Nutr. 2015 Nov;145(11):2622-9. doi: 10.3945/jn.115.217851. Epub 2015 Sep 30.

PMID:
26423740
29.

Maternal folate status and obesity/insulin resistance in the offspring: a systematic review.

Xie RH, Liu YJ, Retnakaran R, MacFarlane AJ, Hamilton J, Smith G, Walker MC, Wen SW.

Int J Obes (Lond). 2016 Jan;40(1):1-9. doi: 10.1038/ijo.2015.189. Epub 2015 Sep 22. Review.

PMID:
26392017
30.

High-dose folic acid supplementation alters the human sperm methylome and is influenced by the MTHFR C677T polymorphism.

Aarabi M, San Gabriel MC, Chan D, Behan NA, Caron M, Pastinen T, Bourque G, MacFarlane AJ, Zini A, Trasler J.

Hum Mol Genet. 2015 Nov 15;24(22):6301-13. doi: 10.1093/hmg/ddv338. Epub 2015 Aug 24.

31.

Altered folate metabolism modifies cell proliferation and progesterone secretion in human placental choriocarcinoma JEG-3 cells.

Moussa C, Ross N, Jolette P, MacFarlane AJ.

Br J Nutr. 2015 Sep 28;114(6):844-52. doi: 10.1017/S0007114515002688. Epub 2015 Aug 24.

PMID:
26299783
32.

Heme Oxygenase-1 Induction Prevents Autoimmune Diabetes in Association With Pancreatic Recruitment of M2-Like Macrophages, Mesenchymal Cells, and Fibrocytes.

Husseini M, Wang GS, Patrick C, Crookshank JA, MacFarlane AJ, Noel JA, Strom A, Scott FW.

Endocrinology. 2015 Nov;156(11):3937-49. doi: 10.1210/en.2015-1304. Epub 2015 Aug 7.

PMID:
26252059
33.

Dietary folic acid protects against genotoxicity in the red blood cells of mice.

MacFarlane AJ, Behan NA, Field MS, Williams A, Stover PJ, Yauk CL.

Mutat Res. 2015 Sep;779:105-11. doi: 10.1016/j.mrfmmm.2015.06.012. Epub 2015 Jun 29.

34.

Bringing clarity to the role of MTHFR variants in neural tube defect prevention.

Stover PJ, MacFarlane AJ, Field MS.

Am J Clin Nutr. 2015 Jun;101(6):1111-2. doi: 10.3945/ajcn.115.111088. Epub 2015 May 13. No abstract available.

35.

Genetic modifiers of folate, vitamin B-12, and homocysteine status in a cross-sectional study of the Canadian population.

Zinck JW, de Groh M, MacFarlane AJ.

Am J Clin Nutr. 2015 Jun;101(6):1295-304. doi: 10.3945/ajcn.115.107219. Epub 2015 May 6.

PMID:
25948668
36.

Effect of body mass index on angle of needle insertion during ultrasound-guided lateral sagittal infraclavicular brachial plexus block.

Kalagara HK, Uppal V, McKinlay S, Macfarlane AJ, Anderson K.

J Clin Anesth. 2015 Aug;27(5):375-9. doi: 10.1016/j.jclinane.2015.03.039. Epub 2015 Apr 29.

PMID:
25935834
37.

Formate metabolism in fetal and neonatal sheep.

Washburn SE, Caudill MA, Malysheva O, MacFarlane AJ, Behan NA, Harnett B, MacMillan L, Pongnopparat T, Brosnan JT, Brosnan ME.

Am J Physiol Endocrinol Metab. 2015 May 15;308(10):E921-7. doi: 10.1152/ajpendo.00046.2015. Epub 2015 Mar 24.

38.

The Requisites of Needle-to-Nerve Proximity for Ultrasound-Guided Regional Anesthesia: A Scoping Review of the Evidence.

Abdallah FW, Macfarlane AJ, Brull R.

Reg Anesth Pain Med. 2016 Mar-Apr;41(2):221-8. doi: 10.1097/AAP.0000000000000201. Review.

PMID:
25785841
39.

Wide differences in mode of delivery within Europe: risk-stratified analyses of aggregated routine data from the Euro-Peristat study.

Macfarlane AJ, Blondel B, Mohangoo AD, Cuttini M, Nijhuis J, Novak Z, Ólafsdóttir HS, Zeitlin J; Euro-Peristat Scientific Committee.

BJOG. 2016 Mar;123(4):559-68. doi: 10.1111/1471-0528.13284. Epub 2015 Mar 9.

40.

In vivo kinetics of formate metabolism in folate-deficient and folate-replete rats.

Morrow GP, MacMillan L, Lamarre SG, Young SK, MacFarlane AJ, Brosnan ME, Brosnan JT.

J Biol Chem. 2015 Jan 23;290(4):2244-50. doi: 10.1074/jbc.M114.600718. Epub 2014 Dec 5.

41.
42.

Survey of women's experiences of care in a new freestanding midwifery unit in an inner city area of London, England: 2. Specific aspects of care.

Macfarlane AJ, Rocca-Ihenacho L, Turner LR.

Midwifery. 2014 Sep;30(9):1009-20. doi: 10.1016/j.midw.2014.05.008. Epub 2014 May 22.

43.

Survey of women's experiences of care in a new freestanding midwifery unit in an inner city area of London, England. 1: Methods and women's overall ratings of care.

Macfarlane AJ, Rocca-Ihenacho L, Turner LR, Roth C.

Midwifery. 2014 Sep;30(9):998-1008. doi: 10.1016/j.midw.2014.03.013. Epub 2014 Mar 29.

44.

High-dose compared with low-dose vitamin B-12 supplement use is not associated with higher vitamin B-12 status in children, adolescents, and older adults.

MacFarlane AJ, Shi Y, Greene-Finestone LS.

J Nutr. 2014 Jun;144(6):915-20. doi: 10.3945/jn.113.190256. Epub 2014 Apr 3.

PMID:
24699807
45.

Diversity and stability of cultured vaginal lactobacilli in pregnant women from a multi-ethnic urban UK population.

Husain SM, Wilks M, Mupita M, Reddy SP, Hennessy EM, Macfarlane AJ, Millar MR.

J Appl Microbiol. 2014 Jul;117(1):258-65. doi: 10.1111/jam.12506. Epub 2014 Apr 17.

46.

Azoxymethane-induced colon carcinogenesis in mice occurs independently of de novo thymidylate synthesis capacity.

MacFarlane AJ, McEntee MF, Stover PJ.

J Nutr. 2014 Apr;144(4):419-24. doi: 10.3945/jn.113.186007. Epub 2014 Feb 5.

47.

Approaches for the identification of genetic modifiers of nutrient dependent phenotypes: examples from folate.

Zinck JW, MacFarlane AJ.

Front Nutr. 2014 Jul 14;1:8. doi: 10.3389/fnut.2014.00008. eCollection 2014. Review.

48.

Does regional compared to local anaesthesia influence outcome after arteriovenous fistula creation?

Macfarlane AJ, Kearns RJ, Aitken E, Kinsella J, Clancy MJ.

Trials. 2013 Aug 19;14:263. doi: 10.1186/1745-6215-14-263.

49.

Dietary folate does not significantly affect the intestinal microbiome, inflammation or tumorigenesis in azoxymethane-dextran sodium sulphate-treated mice.

MacFarlane AJ, Behan NA, Matias FM, Green J, Caldwell D, Brooks SP.

Br J Nutr. 2013 Feb 28;109(4):630-8. doi: 10.1017/S0007114512001857. Epub 2012 Jul 5.

PMID:
23021249
50.

Seed storage proteins of the globulin family are cleaved post-translationally in wheat embryos.

Koziol AG, Loit E, McNulty M, MacFarlane AJ, Scott FW, Altosaar I.

BMC Res Notes. 2012 Jul 28;5:385. doi: 10.1186/1756-0500-5-385.

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