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Items: 27

1.

Potent, Efficacious, and Stable Cyclic Opioid Peptides with Long Lasting Antinociceptive Effect after Peripheral Administration.

Stefanucci A, Dimmito MP, Macedonio G, Ciarlo L, Pieretti S, Novellino E, Lei W, Barlow D, Houseknecht KL, Streicher JM, Mollica A.

J Med Chem. 2020 Mar 12;63(5):2673-2687. doi: 10.1021/acs.jmedchem.9b01963. Epub 2019 Dec 27.

PMID:
31834798
2.

Preparation of bivalent agonists for targeting the mu opioid and cannabinoid receptors.

Dvorácskó S, Keresztes A, Mollica A, Stefanucci A, Macedonio G, Pieretti S, Zádor F, Walter FR, Deli MA, Kékesi G, Bánki L, Tuboly G, Horváth G, Tömböly C.

Eur J Med Chem. 2019 Sep 15;178:571-588. doi: 10.1016/j.ejmech.2019.05.037. Epub 2019 May 21.

PMID:
31220675
3.

First muography of Stromboli volcano.

Tioukov V, Alexandrov A, Bozza C, Consiglio L, D'Ambrosio N, De Lellis G, De Sio C, Giudicepietro F, Macedonio G, Miyamoto S, Nishiyama R, Orazi M, Peluso R, Sheshukov A, Sirignano C, Stellacci SM, Strolin P, Tanaka HKM.

Sci Rep. 2019 Apr 30;9(1):6695. doi: 10.1038/s41598-019-43131-8.

4.

Volcanoes in Italy and the role of muon radiography.

D'Alessandro R, Ambrosino F, Baccani G, Bonechi L, Bongi M, Caputo A, Ciaranfi R, Cimmino L, Ciulli V, D'Errico M, Giudicepietro F, Gonzi S, Macedonio G, Masone V, Melon B, Mori N, Noli P, Orazi M, Passeggio P, Peluso R, Saracino G, Scognamiglio L, Strolin P, Vertechi E, Viliani L.

Philos Trans A Math Phys Eng Sci. 2018 Dec 10;377(2137). pii: 20180050. doi: 10.1098/rsta.2018.0050.

5.

Discovery of arginine-containing tripeptides as a new class of pancreatic lipase inhibitors.

Stefanucci A, Luisi G, Zengin G, Macedonio G, Dimmito MP, Novellino E, Mollica A.

Future Med Chem. 2019 Jan;11(1):5-19. doi: 10.4155/fmc-2018-0216. Epub 2018 Dec 11.

PMID:
30526045
6.

Effects of Kisspeptin-10 on Hypothalamic Neuropeptides and Neurotransmitters Involved in Appetite Control.

Orlando G, Leone S, Ferrante C, Chiavaroli A, Mollica A, Stefanucci A, Macedonio G, Dimmito MP, Leporini L, Menghini L, Brunetti L, Recinella L.

Molecules. 2018 Nov 24;23(12). pii: E3071. doi: 10.3390/molecules23123071.

7.

Novel Fubinaca/Rimonabant hybrids as endocannabinoid system modulators.

Stefanucci A, Macedonio G, Dvorácskó S, Tömböly C, Mollica A.

Amino Acids. 2018 Nov;50(11):1595-1605. doi: 10.1007/s00726-018-2636-1. Epub 2018 Aug 25.

PMID:
30145711
8.

Polyphenolic composition, enzyme inhibitory effects ex-vivo and in-vivo studies on two Brassicaceae of north-central Italy.

Mollica A, Stefanucci A, Zengin G, Locatelli M, Macedonio G, Orlando G, Ferrante C, Menghini L, Recinella L, Leone S, Chiavaroli A, Leporini L, Di Nisio C, Brunetti L, Tayrab E, Ali I, Musa TH, Musa HH, Ahmed AA.

Biomed Pharmacother. 2018 Nov;107:129-138. doi: 10.1016/j.biopha.2018.07.169. Epub 2018 Aug 4.

PMID:
30086459
9.

Effects of central RVD-hemopressin(α) administration on anxiety, feeding behavior and hypothalamic neuromodulators in the rat.

Recinella L, Chiavaroli A, Ferrante C, Mollica A, Macedonio G, Stefanucci A, Dimmito MP, Dvorácskó S, Tömböly C, Brunetti L, Orlando G, Leone S.

Pharmacol Rep. 2018 Aug;70(4):650-657. doi: 10.1016/j.pharep.2018.01.010. Epub 2018 Feb 2.

PMID:
29902669
10.

Cyclic biphalin analogues with a novel linker lead to potent agonist activities at mu, delta, and kappa opioid receptors.

Remesic M, Macedonio G, Mollica A, Porreca F, Hruby V, Lee YS.

Bioorg Med Chem. 2018 Jul 23;26(12):3664-3667. doi: 10.1016/j.bmc.2018.05.045. Epub 2018 May 26.

PMID:
29858157
11.

Impact of different geographical locations on varying profile of bioactives and associated functionalities of caper (Capparis spinosa L.).

Stefanucci A, Zengin G, Locatelli M, Macedonio G, Wang CK, Novellino E, Mahomoodally MF, Mollica A.

Food Chem Toxicol. 2018 Aug;118:181-189. doi: 10.1016/j.fct.2018.05.003. Epub 2018 May 8.

PMID:
29751072
12.

Combinatorial peptide library screening for discovery of diverse α-glucosidase inhibitors using molecular dynamics simulations and binary QSAR models.

Mollica A, Zengin G, Durdagi S, Ekhteiari Salmas R, Macedonio G, Stefanucci A, Dimmito MP, Novellino E.

J Biomol Struct Dyn. 2019 Feb;37(3):726-740. doi: 10.1080/07391102.2018.1439403. Epub 2018 Feb 22.

PMID:
29421954
13.

Five- and Six-Membered Nitrogen-Containing Compounds as Selective Carbonic Anhydrase Activators.

Mollica A, Macedonio G, Stefanucci A, Carradori S, Akdemir A, Angeli A, Supuran CT.

Molecules. 2017 Dec 9;22(12). pii: E2178. doi: 10.3390/molecules22122178.

14.

Anorexigenic effects induced by RVD-hemopressin(α) administration.

Ferrante C, Recinella L, Leone S, Chiavaroli A, Di Nisio C, Martinotti S, Mollica A, Macedonio G, Stefanucci A, Dvorácskó S, Tömböly C, De Petrocellis L, Vacca M, Brunetti L, Orlando G.

Pharmacol Rep. 2017 Dec;69(6):1402-1407. doi: 10.1016/j.pharep.2017.05.015. Epub 2017 Jun 3.

PMID:
29145068
15.

Emotional disorders induced by Hemopressin and RVD-hemopressin(α) administration in rats.

Leone S, Recinella L, Chiavaroli A, Martinotti S, Ferrante C, Mollica A, Macedonio G, Stefanucci A, Dvorácskó S, Tömböly C, De Petrocellis L, Vacca M, Brunetti L, Orlando G.

Pharmacol Rep. 2017 Dec;69(6):1247-1253. doi: 10.1016/j.pharep.2017.06.010. Epub 2017 Jun 23.

PMID:
29128806
16.

Cyclic Biphalin Analogues Incorporating a Xylene Bridge: Synthesis, Characterization, and Biological Profile.

Stefanucci A, Carotenuto A, Macedonio G, Novellino E, Pieretti S, Marzoli F, Szűcs E, Erdei AI, Zádor F, Benyhe S, Mollica A.

ACS Med Chem Lett. 2017 Jul 12;8(8):858-863. doi: 10.1021/acsmedchemlett.7b00210. eCollection 2017 Aug 10.

17.

Fluorescent-labeled bioconjugates of the opioid peptides biphalin and DPDPE incorporating fluorescein-maleimide linkers.

Stefanucci A, Lei W, Hruby VJ, Macedonio G, Luisi G, Carradori S, Streicher JM, Mollica A.

Future Med Chem. 2017 Jun;9(9):859-869. doi: 10.4155/fmc-2016-0232. Epub 2017 Jun 21.

PMID:
28635314
18.

Opioid Receptor Activity and Analgesic Potency of DPDPE Peptide Analogues Containing a Xylene Bridge.

Stefanucci A, Novellino E, Mirzaie S, Macedonio G, Pieretti S, Minosi P, Szűcs E, Erdei AI, Zádor F, Benyhe S, Mollica A.

ACS Med Chem Lett. 2017 Mar 14;8(4):449-454. doi: 10.1021/acsmedchemlett.7b00044. eCollection 2017 Apr 13.

19.

An assessment of the nutraceutical potential of Juglans regia L. leaf powder in diabetic rats.

Mollica A, Zengin G, Locatelli M, Stefanucci A, Macedonio G, Bellagamba G, Onaolapo O, Onaolapo A, Azeez F, Ayileka A, Novellino E.

Food Chem Toxicol. 2017 Sep;107(Pt B):554-564. doi: 10.1016/j.fct.2017.03.056. Epub 2017 Mar 30.

PMID:
28366844
20.

Exploring the first Rimonabant analog-opioid peptide hybrid compound, as bivalent ligand for CB1 and opioid receptors.

Mollica A, Pelliccia S, Famiglini V, Stefanucci A, Macedonio G, Chiavaroli A, Orlando G, Brunetti L, Ferrante C, Pieretti S, Novellino E, Benyhe S, Zador F, Erdei A, Szucs E, Samavati R, Dvrorasko S, Tomboly C, Ragno R, Patsilinakos A, Silvestri R.

J Enzyme Inhib Med Chem. 2017 Dec;32(1):444-451. doi: 10.1080/14756366.2016.1260565.

21.

Hemopressin Peptides as Modulators of the Endocannabinoid System and their Potential Applications as Therapeutic Tools.

Macedonio G, Stefanucci A, Maccallini C, Mirzaie S, Novellino E, Mollica A.

Protein Pept Lett. 2016;23(12):1045-1051. Review.

PMID:
27748182
22.

Microwave-assisted extraction, HPLC analysis, and inhibitory effects on carbonic anhydrase I, II, VA, and VII isoforms of 14 blueberry Italian cultivars.

Mollica A, Locatelli M, Macedonio G, Carradori S, Sobolev AP, De Salvador RF, Monti SM, Buonanno M, Zengin G, Angeli A, Supuran CT.

J Enzyme Inhib Med Chem. 2016;31(sup4):1-6. Epub 2016 Aug 10.

PMID:
27541737
23.

Beyond eruptive scenarios: assessing tephra fallout hazard from Neapolitan volcanoes.

Sandri L, Costa A, Selva J, Tonini R, Macedonio G, Folch A, Sulpizio R.

Sci Rep. 2016 Apr 12;6:24271. doi: 10.1038/srep24271.

24.

Exploring the biological consequences of conformational changes in aspartame models containing constrained analogues of phenylalanine.

Mollica A, Mirzaie S, Costante R, Carradori S, Macedonio G, Stefanucci A, Dvoracsko S, Novellino E.

J Enzyme Inhib Med Chem. 2016 Dec;31(6):953-63. doi: 10.3109/14756366.2015.1076811. Epub 2015 Aug 24.

PMID:
26308194
25.

Magma injection beneath the urban area of Naples: a new mechanism for the 2012-2013 volcanic unrest at Campi Flegrei caldera.

D'Auria L, Pepe S, Castaldo R, Giudicepietro F, Macedonio G, Ricciolino P, Tizzani P, Casu F, Lanari R, Manzo M, Martini M, Sansosti E, Zinno I.

Sci Rep. 2015 Aug 17;5:13100. doi: 10.1038/srep13100.

26.

Exploring new Probenecid-based carbonic anhydrase inhibitors: Synthesis, biological evaluation and docking studies.

Mollica A, Costante R, Akdemir A, Carradori S, Stefanucci A, Macedonio G, Ceruso M, Supuran CT.

Bioorg Med Chem. 2015 Sep 1;23(17):5311-8. doi: 10.1016/j.bmc.2015.07.066. Epub 2015 Aug 1.

PMID:
26264840
27.

Transient dynamics of vulcanian explosions and column collapse.

Clarke AB, Voight B, Neri A, Macedonio G.

Nature. 2002 Feb 21;415(6874):897-901.

PMID:
11859366

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