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Items: 1 to 50 of 267

1.

Assessing Preoperative Mobility in Total Hip Arthroplasty: A SAFE T database study.

Vasarhelyi EM, Morcos MW, Phillips JT, MacDonald SJ, Somerville L, Kreder H, Howard JL; SAFE T Investigators.

J Orthop. 2019 May 2;16(5):409-413. doi: 10.1016/j.jor.2019.04.012. eCollection 2019 Sep-Oct.

PMID:
31193024
2.

Quantitative Genetic Mapping and Genome Assembly in the Lesser Wax Moth Achroia grisella.

Koseva BS, Hackett JL, Zhou Y, Harris BR, Kelly JK, Greenfield MD, Gleason JM, Macdonald SJ.

G3 (Bethesda). 2019 May 17. pii: g3.400090.2019. doi: 10.1534/g3.119.400090. [Epub ahead of print]

3.

Radiostereometric Analysis Permits In Vivo Measurement of Very Small Levels of Wear in TKA.

Teeter MG, Wihlidal J, McCalden RW, Yuan X, MacDonald SJ, Lanting BA, Naudie DD.

Clin Orthop Relat Res. 2019 Jan;477(1):80-90. doi: 10.1097/CORR.0000000000000399.

PMID:
30794231
4.

Dissection of Complex, Fitness-Related Traits in Multiple Drosophila Mapping Populations Offers Insight into the Genetic Control of Stress Resistance.

Everman ER, McNeil CL, Hackett JL, Bain CL, Macdonald SJ.

Genetics. 2019 Apr;211(4):1449-1467. doi: 10.1534/genetics.119.301930. Epub 2019 Feb 13.

5.

Morbid Obesity in Revision Total Knee Arthroplasty: A Significant Risk Factor for Re-Operation.

Sisko ZW, Vasarhelyi EM, Somerville LE, Naudie DD, MacDonald SJ, McCalden RW.

J Arthroplasty. 2019 May;34(5):932-938. doi: 10.1016/j.arth.2019.01.010. Epub 2019 Jan 14.

PMID:
30745083
6.

Twice upon a time: Examining the effect socio-economic status has on the experience of dyslexia in the United Kingdom.

Macdonald SJ, Deacon L.

Dyslexia. 2019 Feb;25(1):3-19. doi: 10.1002/dys.1606. Epub 2019 Jan 7.

PMID:
30614597
7.

'Loneliness in the city': examining socio-economics, loneliness and poor health in the North East of England.

Macdonald SJ, Nixon J, Deacon L.

Public Health. 2018 Dec;165:88-94. doi: 10.1016/j.puhe.2018.09.003. Epub 2018 Oct 27.

PMID:
30384033
8.

Synthetic Graft Compared With Allograft Reconstruction for Extensor Mechanism Disruption in Total Knee Arthroplasty: A Multicenter Cohort Study.

Wood TJ, Leighton J, Backstein DJ, Marsh JD, Howard JL, McCalden RW, MacDonald SJ, Lanting BA.

J Am Acad Orthop Surg. 2019 Jun 15;27(12):451-457. doi: 10.5435/JAAOS-D-18-00393.

PMID:
30379759
9.

Discovery of ( S)-3-(3-(3,5-Dimethyl-1 H-pyrazol-1-yl)phenyl)-4-(( R)-3-(2-(5,6,7,8-tetrahydro-1,8-naphthyridin-2-yl)ethyl)pyrrolidin-1-yl)butanoic Acid, a Nonpeptidic αvβ6 Integrin Inhibitor for the Inhaled Treatment of Idiopathic Pulmonary Fibrosis.

Procopiou PA, Anderson NA, Barrett J, Barrett TN, Crawford MHJ, Fallon BJ, Hancock AP, Le J, Lemma S, Marshall RP, Morrell J, Pritchard JM, Rowedder JE, Saklatvala P, Slack RJ, Sollis SL, Suckling CJ, Thorp LR, Vitulli G, Macdonald SJF.

J Med Chem. 2018 Sep 27;61(18):8417-8443. doi: 10.1021/acs.jmedchem.8b00959. Epub 2018 Sep 14.

PMID:
30215258
10.

Corrigendum to 'Factors Affecting Wear of Constrained Polyethylene Tibial Inserts in Total Knee Arthroplasty' [Journal of Arthroplasty 31 (2016) 1340-1345].

Pang HN, Bin Abd Razak HR, Jamieson P, Teeter MG, Naudie DDR, MacDonald SJ.

J Arthroplasty. 2018 Nov;33(11):3593. doi: 10.1016/j.arth.2018.07.026. Epub 2018 Aug 16. No abstract available.

PMID:
30122433
11.

Patellar Resurfacing in Total Knee Arthroplasty: A Cost-Effectiveness Analysis.

Weeks CA, Marsh JD, MacDonald SJ, Graves S, Vasarhelyi EM.

J Arthroplasty. 2018 Nov;33(11):3412-3415. doi: 10.1016/j.arth.2018.07.001. Epub 2018 Jul 10.

PMID:
30122432
12.

Highly crosslinked polyethylene wear rates and acetabular component orientation: a minimum ten-year follow-up.

Teeter MG, Lanting BA, Naudie DD, McCalden RW, Howard JL, MacDonald SJ.

Bone Joint J. 2018 Jul;100-B(7):891-897. doi: 10.1302/0301-620X.100B7.BJJ-2017-1457.R3.

PMID:
29954202
13.

The effect of altering head length on corrosion using a material loss method.

Lanting BA, Wood TJ, Young S, Van Citters DW, MacDonald SJ, Howard JL, Teeter MG.

Hip Int. 2019 Jul;29(4):368-372. doi: 10.1177/1120700018779886. Epub 2018 May 29.

PMID:
29808723
14.

Predictive accuracy of RSA migration thresholds for cemented total hip arthroplasty stem designs.

Teeter MG, McCalden RW, Yuan X, MacDonald SJ, Naudie DD.

Hip Int. 2018 Jul;28(4):363-368. doi: 10.1177/1120700018762179. Epub 2018 May 20.

PMID:
29781291
15.

Effect of an e-Learning Tool on Expectations and Satisfaction Following Total Knee Arthroplasty: A Randomized Controlled Trial.

Culliton SE, Bryant DM, MacDonald SJ, Hibbert KM, Chesworth BM.

J Arthroplasty. 2018 Jul;33(7):2153-2158. doi: 10.1016/j.arth.2018.02.040. Epub 2018 Feb 17.

PMID:
29555496
16.

Validity and Internal Consistency of the New Knee Society Knee Scoring System.

Culliton SE, Bryant DM, MacDonald SJ, Hibbert KM, Chesworth BM.

Clin Orthop Relat Res. 2018 Jan;476(1):77-84. doi: 10.1007/s11999.0000000000000014.

17.

Aspirin or Rivaroxaban for VTE Prophylaxis after Hip or Knee Arthroplasty.

Anderson DR, Dunbar M, Murnaghan J, Kahn SR, Gross P, Forsythe M, Pelet S, Fisher W, Belzile E, Dolan S, Crowther M, Bohm E, MacDonald SJ, Gofton W, Kim P, Zukor D, Pleasance S, Andreou P, Doucette S, Theriault C, Abianui A, Carrier M, Kovacs MJ, Rodger MA, Coyle D, Wells PS, Vendittoli PA.

N Engl J Med. 2018 Feb 22;378(8):699-707. doi: 10.1056/NEJMoa1712746.

18.

Inducible displacement of cemented tibial components ten years after total knee arthroplasty.

Lam Tin Cheung K, Lanting BA, McCalden RW, Yuan X, MacDonald SJ, Naudie DD, Teeter MG.

Bone Joint J. 2018 Feb;100-B(2):170-175. doi: 10.1302/0301-620X.100B2.BJJ-2017-0428.R2.

PMID:
29437058
19.

Active Search for Computer-aided Drug Design.

Oglic D, Oatley SA, Macdonald SJF, Mcinally T, Garnett R, Hirst JD, Gärtner T.

Mol Inform. 2018 Jan;37(1-2). doi: 10.1002/minf.201700130. Epub 2018 Feb 1.

PMID:
29388736
20.

Herpes Simplex Virus 1 Mutant with Point Mutations in UL39 Is Impaired for Acute Viral Replication in Mice, Establishment of Latency, and Explant-Induced Reactivation.

Mostafa HH, Thompson TW, Konen AJ, Haenchen SD, Hilliard JG, Macdonald SJ, Morrison LA, Davido DJ.

J Virol. 2018 Mar 14;92(7). pii: e01654-17. doi: 10.1128/JVI.01654-17. Print 2018 Apr 1.

21.

Does Time to Surgery Affect Outcomes for Periprosthetic Femur Fractures?

Sellan ME, Lanting BA, Schemitsch EH, MacDonald SJ, Vasarhelyi EM, Howard JL.

J Arthroplasty. 2018 Mar;33(3):878-881. doi: 10.1016/j.arth.2017.10.045. Epub 2017 Nov 9.

PMID:
29174404
22.

Correction to The Discovery of Novel Antimalarial Aminoxadiazoles as a Promising Nonendoperoxide Scaffold.

Sandoval E, Lafuente-Monasterio MJ, Almela MJ, Castañeda P, Jiménez Díaz MB, Martínez-Martínez MS, Vidal J, Angulo-Barturen Í, Bamborough P, Burrows J, Cammack N, Chaparro MJ, Coterón JM, de Cozar C, Crespo B, Díaz B, Drewes G, Fernández E, Ferrer-Bazaga S, Fraile MT, Gamo FJ, Ghidelli-Disse S, Gómez R, Haselden J, Huss S, León ML, de Mercado J, Macdonald SJF, Martín Hernando JI, Prats S, Puente M, Rodríguez A, de la Rosa JC, Rueda L, Selenski C, Willis P, Wilson DM, Witty M, Calderón F.

J Med Chem. 2017 Dec 14;60(23):9911. doi: 10.1021/acs.jmedchem.7b01491. Epub 2017 Nov 22. No abstract available.

PMID:
29164877
23.

Varus tibial alignment is associated with greater tibial baseplate migration at 10 years following total knee arthroplasty.

Teeter MG, Naudie DD, McCalden RW, Yuan X, Holdsworth DW, MacDonald SJ, Lanting BA.

Knee Surg Sports Traumatol Arthrosc. 2018 Jun;26(6):1610-1617. doi: 10.1007/s00167-017-4765-6. Epub 2017 Nov 16.

PMID:
29147742
24.

Medicinal chemistry in drug discovery in big pharma: past, present and future.

Campbell IB, Macdonald SJF, Procopiou PA.

Drug Discov Today. 2018 Feb;23(2):219-234. doi: 10.1016/j.drudis.2017.10.007. Epub 2017 Oct 12. Review.

PMID:
29031621
25.

An αv-RGD Integrin Inhibitor Toolbox: Drug Discovery Insight, Challenges and Opportunities.

Hatley RJD, Macdonald SJF, Slack RJ, Le J, Ludbrook SB, Lukey PT.

Angew Chem Int Ed Engl. 2018 Mar 19;57(13):3298-3321. doi: 10.1002/anie.201707948. Epub 2018 Feb 21. Review.

PMID:
28944552
26.

Current Total Knee Designs: Does Baseplate Roughness or Locking Mechanism Design Affect Polyethylene Backside Wear?

Sisko ZW, Teeter MG, Lanting BA, Howard JL, McCalden RW, Naudie DD, MacDonald SJ, Vasarhelyi EM.

Clin Orthop Relat Res. 2017 Dec;475(12):2970-2980. doi: 10.1007/s11999-017-5494-3. Epub 2017 Sep 13.

27.

Can asexuality confer a short-term advantage? Investigating apparent biogeographic success in the apomictic triploid fern Myriopteris gracilis.

Wickell DA, Windham MD, Wang X, Macdonald SJ, Beck JB.

Am J Bot. 2017 Aug;104(8):1254-1265. doi: 10.3732/ajb.1700126.

28.

The Discovery of Novel Antimalarial Aminoxadiazoles as a Promising Nonendoperoxide Scaffold.

Sandoval E, Lafuente-Monasterio MJ, Almela MJ, Castañeda P, Jiménez Díaz MB, Martínez-Martínez MS, Vidal J, Angulo-Barturen Í, Bamborough P, Burrows J, Cammack N, Chaparro MJ, Coterón JM, de Cozar C, Crespo B, Díaz B, Drewes G, Fernández E, Ferrer-Bazaga S, Fraile MT, Gamo FJ, Ghidelli-Disse S, Gómez R, Haselden J, Huss S, León ML, de Mercado J, Macdonald SJF, Martín Hernando JI, Prats S, Puente M, Rodríguez A, de la Rosa JC, Rueda L, Selenski C, Willis P, Wilson DM, Witty M, Calderón F.

J Med Chem. 2017 Aug 24;60(16):6880-6896. doi: 10.1021/acs.jmedchem.6b01441. Epub 2017 Aug 14. Erratum in: J Med Chem. 2017 Dec 14;60(23):9911.

PMID:
28806082
29.

Naturally Segregating Variation at Ugt86Dd Contributes to Nicotine Resistance in Drosophila melanogaster.

Highfill CA, Tran JH, Nguyen SKT, Moldenhauer TR, Wang X, Macdonald SJ.

Genetics. 2017 Sep;207(1):311-325. doi: 10.1534/genetics.117.300058. Epub 2017 Jul 25.

30.

Loci Contributing to Boric Acid Toxicity in Two Reference Populations of Drosophila melanogaster.

Najarro MA, Hackett JL, Macdonald SJ.

G3 (Bethesda). 2017 Jun 7;7(6):1631-1641. doi: 10.1534/g3.117.041418.

31.

Morbid Obesity Is a Significant Risk of Failure Following Revision Total Hip Arthroplasty.

Hanna SA, McCalden RW, Somerville L, Howard JL, Naudie DD, MacDonald SJ.

J Arthroplasty. 2017 Oct;32(10):3098-3101. doi: 10.1016/j.arth.2017.05.014. Epub 2017 May 17.

PMID:
28583759
32.
33.

Unusual Undergraduate Training in Medicinal Chemistry in Collaboration between Academia and Industry.

McInally T, Macdonald SJF.

J Med Chem. 2017 Oct 12;60(19):7958-7964. doi: 10.1021/acs.jmedchem.7b00198. Epub 2017 May 23. Review.

PMID:
28535049
34.

The role of isolated polyethylene exchange in total knee arthroplasty.

Pang HN, Bin Abd Razak HR, Petis S, Naudie DDR, MacDonald SJ.

EFORT Open Rev. 2017 Apr 27;2(3):66-71. doi: 10.1302/2058-5241.2.160049. eCollection 2017 Mar. Review.

35.

Metal-on-Metal Compared With Metal-on-Polyethylene: The Effect on Trunnion Corrosion in Total Hip Arthroplasty.

Lanting BA, Teeter MG, Howard JL, MacDonald SJ, Van Citters DW.

J Arthroplasty. 2017 Aug;32(8):2574-2579. doi: 10.1016/j.arth.2017.03.012. Epub 2017 Mar 29.

PMID:
28483210
36.

Alterations in amino acid status in cats with feline dysautonomia.

McGorum BC, Symonds HW, Knottenbelt C, Cave TA, MacDonald SJ, Stratton J, Leon I, Turner JA, Pirie RS.

PLoS One. 2017 Mar 23;12(3):e0174346. doi: 10.1371/journal.pone.0174346. eCollection 2017.

37.

Clinical Results and Survivorship of the GENESIS II Total Knee Arthroplasty at a Minimum of 15 Years.

McCalden RW, Hart GP, MacDonald SJ, Naudie DD, Howard JH, Bourne RB.

J Arthroplasty. 2017 Jul;32(7):2161-2166. doi: 10.1016/j.arth.2017.02.006. Epub 2017 Feb 16.

PMID:
28285899
38.
39.

The Impact of Coronal Plane Alignment on Polyethylene Wear and Damage in Total Knee Arthroplasty: A Retrieval Study.

Vandekerckhove PTK, Teeter MG, Naudie DDR, Howard JL, MacDonald SJ, Lanting BA.

J Arthroplasty. 2017 Jun;32(6):2012-2016. doi: 10.1016/j.arth.2016.12.048. Epub 2017 Jan 4.

PMID:
28209278
40.

Rational Design of Autotaxin Inhibitors by Structural Evolution of Endogenous Modulators.

Keune WJ, Potjewyd F, Heidebrecht T, Salgado-Polo F, Macdonald SJ, Chelvarajan L, Abdel Latif A, Soman S, Morris AJ, Watson AJ, Jamieson C, Perrakis A.

J Med Chem. 2017 Mar 9;60(5):2006-2017. doi: 10.1021/acs.jmedchem.6b01743. Epub 2017 Feb 16.

41.

Emergence of Small-Molecule Non-RGD-Mimetic Inhibitors for RGD Integrins.

Miller LM, Pritchard JM, Macdonald SJF, Jamieson C, Watson AJB.

J Med Chem. 2017 Apr 27;60(8):3241-3251. doi: 10.1021/acs.jmedchem.6b01711. Epub 2017 Feb 15. Review.

42.

Design and Elaboration of a Tractable Tricyclic Scaffold To Synthesize Druglike Inhibitors of Dipeptidyl Peptidase-4 (DPP-4), Antagonists of the C-C Chemokine Receptor Type 5 (CCR5), and Highly Potent and Selective Phosphoinositol-3 Kinase δ (PI3Kδ) Inhibitors.

Schwehm C, Kellam B, Garces AE, Hill SJ, Kindon ND, Bradshaw TD, Li J, Macdonald SJ, Rowedder JE, Stoddart LA, Stocks MJ.

J Med Chem. 2017 Feb 23;60(4):1534-1554. doi: 10.1021/acs.jmedchem.6b01801. Epub 2017 Feb 10.

43.

Structure-Activity Relationships of Small Molecule Autotaxin Inhibitors with a Discrete Binding Mode.

Miller LM, Keune WJ, Castagna D, Young LC, Duffy EL, Potjewyd F, Salgado-Polo F, Engel García P, Semaan D, Pritchard JM, Perrakis A, Macdonald SJ, Jamieson C, Watson AJ.

J Med Chem. 2017 Jan 26;60(2):722-748. doi: 10.1021/acs.jmedchem.6b01597. Epub 2017 Jan 5.

44.

Functional outcomes of infected hip arthroplasty: a comparison of different surgical treatment options.

Herman BV, Nyland M, Somerville L, MacDonald SJ, Lanting BA, Howard JL.

Hip Int. 2017 May 12;27(3):245-250. doi: 10.5301/hipint.5000455. Epub 2016 Nov 28.

PMID:
27911455
45.

Heterocyclic replacements for benzene: Maximising ADME benefits by considering individual ring isomers.

Ritchie TJ, Macdonald SJF.

Eur J Med Chem. 2016 Nov 29;124:1057-1068. doi: 10.1016/j.ejmech.2016.10.029. Epub 2016 Oct 15. Review.

PMID:
27783976
46.

Do Changes in Patellofemoral Joint Offset Lead to Adverse Outcomes in Total Knee Arthroplasty With Patellar Resurfacing? A Radiographic Review.

Matz J, Howard JL, Morden DJ, MacDonald SJ, Teeter MG, Lanting BA.

J Arthroplasty. 2017 Mar;32(3):783-787.e1. doi: 10.1016/j.arth.2016.08.032. Epub 2016 Sep 14.

PMID:
27720514
47.

Mapping QTL Contributing to Variation in Posterior Lobe Morphology between Strains of Drosophila melanogaster.

Hackett JL, Wang X, Smith BR, Macdonald SJ.

PLoS One. 2016 Sep 8;11(9):e0162573. doi: 10.1371/journal.pone.0162573. eCollection 2016.

48.

Genetic dissection of intraspecific variation in a male-specific sexual trait in Drosophila melanogaster.

Cloud-Richardson KM, Smith BR, Macdonald SJ.

Heredity (Edinb). 2016 Dec;117(6):417-426. doi: 10.1038/hdy.2016.63. Epub 2016 Aug 17.

49.

Genetic analysis of variation in lifespan using a multiparental advanced intercross Drosophila mapping population.

Highfill CA, Reeves GA, Macdonald SJ.

BMC Genet. 2016 Aug 2;17:113. doi: 10.1186/s12863-016-0419-9.

50.

Corrigendum: Intrinsic challenges in ancient microbiome reconstruction using 16S rRNA gene amplification.

Ziesemer KA, Mann AE, Sankaranarayanan K, Schroeder H, Ozga AT, Brandt BW, Zaura E, Waters-Rist A, Hoogland M, Salazar-García DC, Aldenderfer M, Speller C, Hendy J, Weston DA, MacDonald SJ, Thomas GH, Collins MJ, Lewis CM, Hofman C, Warinner C.

Sci Rep. 2016 Jun 2;6:27163. doi: 10.1038/srep27163. No abstract available.

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