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Items: 1 to 50 of 664

1.

Significance of fluctuations in serum sodium levels following aneurysmal subarachnoid hemorrhage: an exploratory analysis.

Eagles ME, Tso MK, Macdonald RL.

J Neurosurg. 2018 Aug 17:1-6. doi: 10.3171/2018.3.JNS173068. [Epub ahead of print]

PMID:
30117765
2.

GABA beyond the synapse: defining the subtype-specific pharmacodynamics of non-synaptic GABAA receptors.

Lagrange AH, Hu N, Macdonald RL.

J Physiol. 2018 Jul 17. doi: 10.1113/JP276187. [Epub ahead of print]

PMID:
30019335
3.
4.

Surgical or endovascular management of ruptured intracranial aneurysms: an agreement study.

Darsaut TE, Fahed R, Macdonald RL, Arthur AS, Kalani MYS, Arikan F, Roy D, Weill A, Bilocq A, Rempel JL, Chow MM, Ashforth RA, Findlay JM, Castro-Afonso LH, Chagnon M, Gevry G, Raymond J.

J Neurosurg. 2018 Jul 13:1-7. doi: 10.3171/2018.1.JNS172645. [Epub ahead of print]

PMID:
30004285
5.

Whole exome sequencing reveals novel NOV and DCAF13 variants in a Chinese pedigree with familial cortical myoclonic tremor with epilepsy.

Lin H, Hu N, Zhang Y, Wang Y, Macdonald RL.

Neurosci Lett. 2018 Jul 9;684:115-120. doi: 10.1016/j.neulet.2018.07.014. [Epub ahead of print]

PMID:
30003937
6.

Anemia After Aneurysmal Subarachnoid Hemorrhage Is Associated With Poor Outcome and Death.

Ayling OGS, Ibrahim GM, Alotaibi NM, Gooderham PA, Macdonald RL.

Stroke. 2018 Jun 26. pii: STROKEAHA.117.020260. doi: 10.1161/STROKEAHA.117.020260. [Epub ahead of print]

PMID:
29946013
7.

Single Quantum Dot Tracking Reveals Serotonin Transporter Diffusion Dynamics are Correlated with Cholesterol-Sensitive Threonine 276 Phosphorylation Status in Primary Midbrain Neurons.

Bailey DM, Catron MA, Kovtun O, Macdonald RL, Zhang Q, Rosenthal SJ.

ACS Chem Neurosci. 2018 May 24. doi: 10.1021/acschemneuro.8b00214. [Epub ahead of print]

PMID:
29787674
8.

Neuroinflammation as a Target for Intervention in Subarachnoid Hemorrhage.

de Oliveira Manoel AL, Macdonald RL.

Front Neurol. 2018 May 2;9:292. doi: 10.3389/fneur.2018.00292. eCollection 2018. Review.

9.

Role of von Willebrand factor and ADAMTS-13 in early brain injury after experimental subarachnoid hemorrhage.

Wan H, Wang Y, Ai J, Brathwaite S, Ni H, Macdonald RL, Hol EM, Meijers JCM, Vergouwen MDI.

J Thromb Haemost. 2018 Jul;16(7):1413-1422. doi: 10.1111/jth.14136. Epub 2018 Jun 8.

10.

A Case-Control Study Investigating Simulated Driving Errors in Ischemic Stroke and Subarachnoid Hemorrhage.

Hird MA, Vesely KA, Tasneem T, Saposnik G, Macdonald RL, Schweizer TA.

Front Neurol. 2018 Feb 13;9:54. doi: 10.3389/fneur.2018.00054. eCollection 2018.

11.

Intrapatient study comparing 3D printed bolus versus standard vinyl gel sheet bolus for postmastectomy chest wall radiation therapy.

Robar JL, Moran K, Allan J, Clancey J, Joseph T, Chytyk-Praznik K, MacDonald RL, Lincoln J, Sadeghi P, Rutledge R.

Pract Radiat Oncol. 2018 Jul - Aug;8(4):221-229. doi: 10.1016/j.prro.2017.12.008. Epub 2017 Dec 24.

12.

A Missense Mutation A384P Associated with Human Hyperekplexia Reveals a Desensitization Site of Glycine Receptors.

Wang CH, Hernandez CC, Wu J, Zhou N, Hsu HY, Shen ML, Wang YC, Macdonald RL, Wu DC.

J Neurosci. 2018 Mar 14;38(11):2818-2831. doi: 10.1523/JNEUROSCI.0674-16.2018. Epub 2018 Feb 13.

PMID:
29440552
13.

Construction of a coarse-grain quasi-classical trajectory method. I. Theory and application to N2-N2 system.

Macdonald RL, Jaffe RL, Schwenke DW, Panesi M.

J Chem Phys. 2018 Feb 7;148(5):054309. doi: 10.1063/1.5011331.

PMID:
29421898
14.

Construction of a coarse-grain quasi-classical trajectory method. II. Comparison against the direct molecular simulation method.

Macdonald RL, Grover MS, Schwartzentruber TE, Panesi M.

J Chem Phys. 2018 Feb 7;148(5):054310. doi: 10.1063/1.5011332.

PMID:
29421878
15.

Glioblastoma Following Ischemic Stroke.

Alotaibi NM, Samuel N, Mansouri A, Nejad R, Macdonald RL.

Can J Neurol Sci. 2017 Nov;44(6):732-733. doi: 10.1017/cjn.2017.220. No abstract available.

PMID:
29391081
16.

Development and validation of outcome prediction models for aneurysmal subarachnoid haemorrhage: the SAHIT multinational cohort study.

Jaja BNR, Saposnik G, Lingsma HF, Macdonald E, Thorpe KE, Mamdani M, Steyerberg EW, Molyneux A, Manoel ALO, Schatlo B, Hanggi D, Hasan D, Wong GKC, Etminan N, Fukuda H, Torner J, Schaller KL, Suarez JI, Stienen MN, Vergouwen MDI, Rinkel GJE, Spears J, Cusimano MD, Todd M, Le Roux P, Kirkpatrick P, Pickard J, van den Bergh WM, Murray G, Johnston SC, Yamagata S, Mayer S, Schweizer TA, Macdonald RL; SAHIT collaboration.

BMJ. 2018 Jan 18;360:j5745. doi: 10.1136/bmj.j5745.

17.

GABA A Receptor Coupling Junction and Pore GABRB3 Mutations are Linked to Early-Onset Epileptic Encephalopathy.

Hernandez CC, Zhang Y, Hu N, Shen D, Shen W, Liu X, Kong W, Jiang Y, Macdonald RL.

Sci Rep. 2017 Nov 21;7(1):15903. doi: 10.1038/s41598-017-16010-3.

18.

Suboccipital Decompressive Craniectomy for Cerebellar Infarction: A Systematic Review and Meta-Analysis.

Ayling OGS, Alotaibi NM, Wang JZ, Fatehi M, Ibrahim GM, Benavente O, Field TS, Gooderham PA, Macdonald RL.

World Neurosurg. 2018 Feb;110:450-459.e5. doi: 10.1016/j.wneu.2017.10.144. Epub 2017 Dec 2. Review.

PMID:
29104155
19.

Dynamic collimator trajectory algorithm for multiple metastases dynamic conformal arc treatment planning.

MacDonald RL, Thomas CG, Syme A.

Med Phys. 2018 Jan;45(1):5-17. doi: 10.1002/mp.12648. Epub 2017 Nov 27.

PMID:
29094419
20.

Management of raised intracranial pressure in aneurysmal subarachnoid hemorrhage: time for a consensus?

Alotaibi NM, Wang JZ, Pasarikovski CR, Guha D, Al-Mufti F, Mamdani M, Saposnik G, Schweizer TA, Macdonald RL.

Neurosurg Focus. 2017 Nov;43(5):E13. doi: 10.3171/2017.7.FOCUS17426. Review.

PMID:
29088956
21.

The SAFARI Score to Assess the Risk of Convulsive Seizure During Admission for Aneurysmal Subarachnoid Hemorrhage.

Jaja BNR, Schweizer TA, Claassen J, Le Roux P, Mayer SA, Macdonald RL; SAHIT Collaborators.

Neurosurgery. 2018 Jun 1;82(6):887-893. doi: 10.1093/neuros/nyx334.

PMID:
28973169
22.

Sex differences in delayed cerebral ischemia after subarachnoid hemorrhage.

Germans MR, Jaja BNR, de Oliviera Manoel AL, Cohen AH, Macdonald RL.

J Neurosurg. 2018 Aug;129(2):458-464. doi: 10.3171/2017.3.JNS162808. Epub 2017 Sep 1.

PMID:
28862545
23.

Neurosurgeon academic impact is associated with clinical outcomes after clipping of ruptured intracranial aneurysms.

Alotaibi NM, Ibrahim GM, Wang J, Guha D, Mamdani M, Schweizer TA, Macdonald RL.

PLoS One. 2017 Jul 20;12(7):e0181521. doi: 10.1371/journal.pone.0181521. eCollection 2017.

24.

Overexpressing wild-type γ2 subunits rescued the seizure phenotype in Gabrg2+/Q390X Dravet syndrome mice.

Huang X, Zhou C, Tian M, Kang JQ, Shen W, Verdier K, Pimenta A, MacDonald RL.

Epilepsia. 2017 Aug;58(8):1451-1461. doi: 10.1111/epi.13810. Epub 2017 Jun 6.

25.

Hypertonic Saline for Increased Intracranial Pressure After Aneurysmal Subarachnoid Hemorrhage: A Systematic Review.

Pasarikovski CR, Alotaibi NM, Al-Mufti F, Macdonald RL.

World Neurosurg. 2017 Sep;105:1-6. doi: 10.1016/j.wneu.2017.05.085. Epub 2017 May 23. Review.

PMID:
28549643
26.

Heat induced temperature dysregulation and seizures in Dravet Syndrome/GEFS+ Gabrg2+/Q390X mice.

Warner TA, Liu Z, Macdonald RL, Kang JQ.

Epilepsy Res. 2017 Aug;134:1-8. doi: 10.1016/j.eplepsyres.2017.04.020. Epub 2017 Apr 30.

27.
28.

Internet search volumes in brain aneurysms and subarachnoid hemorrhage: Is there evidence of seasonality?

Ku JC, Alotaibi NM, Wang J, Ibrahim GM, Schweizer TA, Macdonald RL.

Clin Neurol Neurosurg. 2017 Jul;158:1-4. doi: 10.1016/j.clineuro.2017.04.008. Epub 2017 Apr 6.

PMID:
28412503
29.

Perioperative Management of Anticoagulation.

Guha D, Macdonald RL.

Neurosurg Clin N Am. 2017 Apr;28(2):287-295. doi: 10.1016/j.nec.2016.11.011. Epub 2017 Feb 1. Review.

PMID:
28325463
31.

Changes in Cerebral Perfusion with Induced Hypertension in Aneurysmal Subarachnoid Hemorrhage: A Pilot and Feasibility Study.

Murphy A, de Oliveira Manoel AL, Macdonald RL, Baker A, Lee TY, Marotta T, Montanera W, Aviv R, Bharatha A.

Neurocrit Care. 2017 Aug;27(1):3-10. doi: 10.1007/s12028-017-0379-6.

PMID:
28244000
32.

Management of aneurysmal subarachnoid hemorrhage: State of the art and future perspectives.

Grasso G, Alafaci C, Macdonald RL.

Surg Neurol Int. 2017 Jan 19;8:11. doi: 10.4103/2152-7806.198738. eCollection 2017. Review. Erratum in: Surg Neurol Int. 2017 Apr 26;8:71.

33.

Altered Channel Conductance States and Gating of GABAA Receptors by a Pore Mutation Linked to Dravet Syndrome.

Hernandez CC, Kong W, Hu N, Zhang Y, Shen W, Jackson L, Liu X, Jiang Y, Macdonald RL.

eNeuro. 2017 Feb 10;4(1). pii: ENEURO.0251-16.2017. doi: 10.1523/ENEURO.0251-16.2017. eCollection 2017 Jan-Feb.

34.

Management of aneurysmal subarachnoid hemorrhage.

Etminan N, Macdonald RL.

Handb Clin Neurol. 2017;140:195-228. doi: 10.1016/B978-0-444-63600-3.00012-X. Review.

PMID:
28187800
35.

History of neurosurgery at University of Toronto: the St. Michael's story.

Alotaibi NM, Guha D, Ahuja CS, Spears J, Muller PJ, Tucker WS, Hudson AR, Macdonald RL.

J Neurosurg. 2017 Dec;127(6):1417-1425. doi: 10.3171/2016.9.JNS161119. Epub 2017 Jan 27.

PMID:
28128690
36.

Meta-analysis of timing of endovascular aneurysm treatment in subarachnoid haemorrhage: inconsistent results of early treatment within 1 day.

Rawal S, Alcaide-Leon P, Macdonald RL, Rinkel GJ, Victor JC, Krings T, Kapral MK, Laupacis A.

J Neurol Neurosurg Psychiatry. 2017 Mar;88(3):241-248. doi: 10.1136/jnnp-2016-314596. Epub 2017 Jan 18. Review.

PMID:
28100721
37.

Effects of decompressive craniectomy on functional outcomes and death in poor-grade aneurysmal subarachnoid hemorrhage: a systematic review and meta-analysis.

Alotaibi NM, Elkarim GA, Samuel N, Ayling OGS, Guha D, Fallah A, Aldakkan A, Jaja BNR, de Oliveira Manoel AL, Ibrahim GM, Macdonald RL.

J Neurosurg. 2017 Dec;127(6):1315-1325. doi: 10.3171/2016.9.JNS161383. Epub 2017 Jan 6.

PMID:
28059660
38.

Overlap-guided fixed-patient support positioning optimization for cranial SRT.

MacDonald RL, Robar JL, Thomas CG.

Med Phys. 2017 Jan;44(1):17-27. doi: 10.1002/mp.12008. Epub 2017 Jan 3.

PMID:
28044324
39.

Beyond Epilepsy and Autism: Disruption of GABRB3 Causes Ocular Hypopigmentation.

Delahanty RJ, Zhang Y, Bichell TJ, Shen W, Verdier K, Macdonald RL, Xu L, Boyd K, Williams J, Kang JQ.

Cell Rep. 2016 Dec 20;17(12):3115-3124. doi: 10.1016/j.celrep.2016.11.067.

40.

Biomarkers of Glycocalyx Injury are Associated with Delayed Cerebral Ischemia Following Aneurysmal Subarachnoid Hemorrhage: A Case Series Supporting a New Hypothesis.

Bell JD, Rhind SG, Di Battista AP, Macdonald RL, Baker AJ.

Neurocrit Care. 2017 Jun;26(3):339-347. doi: 10.1007/s12028-016-0357-4.

PMID:
28000132
41.

Low-Dose Lithium Stabilizes Human Endothelial Barrier by Decreasing MLC Phosphorylation and Universally Augments Cholinergic Vasorelaxation Capacity in a Direct Manner.

Bosche B, Molcanyi M, Rej S, Doeppner TR, Obermann M, Müller DJ, Das A, Hescheler J, Macdonald RL, Noll T, Härtel FV.

Front Physiol. 2016 Dec 6;7:593. doi: 10.3389/fphys.2016.00593. eCollection 2016.

42.

Randomized, Open-Label, Phase 1/2a Study to Determine the Maximum Tolerated Dose of Intraventricular Sustained Release Nimodipine for Subarachnoid Hemorrhage (NEWTON [Nimodipine Microparticles to Enhance Recovery While Reducing Toxicity After Subarachnoid Hemorrhage]).

Hänggi D, Etminan N, Aldrich F, Steiger HJ, Mayer SA, Diringer MN, Hoh BL, Mocco J, Faleck HJ, Macdonald RL; NEWTON Investigators.

Stroke. 2017 Jan;48(1):145-151. doi: 10.1161/STROKEAHA.116.014250. Epub 2016 Dec 8.

43.

Neuroprotection in Critical Care Neurology.

Germans MR, Boogaarts HD, Macdonald RL.

Semin Neurol. 2016 Dec;36(6):642-648. Epub 2016 Dec 1. Review.

PMID:
27907969
44.

The Use of Social Media Communications in Brain Aneurysms and Subarachnoid Hemorrhage: A Mixed-Method Analysis.

Alotaibi NM, Samuel N, Wang J, Ahuja CS, Guha D, Ibrahim GM, Schweizer TA, Saposnik G, Macdonald RL.

World Neurosurg. 2017 Feb;98:456-462. doi: 10.1016/j.wneu.2016.11.085. Epub 2016 Nov 24.

PMID:
27890750
45.

Correction: Deleterious Rare Variants Reveal Risk for Loss of GABAA Receptor Function in Patients with Genetic Epilepsy and in the General Population.

Hernandez CC, Klassen TL, Jackson LG, Gurba K, Hu N, Noebels JL, Macdonald RL.

PLoS One. 2016 Nov 21;11(11):e0167264. doi: 10.1371/journal.pone.0167264. eCollection 2016.

46.

De novo GABRG2 mutations associated with epileptic encephalopathies.

Shen D, Hernandez CC, Shen W, Hu N, Poduri A, Shiedley B, Rotenberg A, Datta AN, Leiz S, Patzer S, Boor R, Ramsey K, Goldberg E, Helbig I, Ortiz-Gonzalez XR, Lemke JR, Marsh ED, Macdonald RL.

Brain. 2017 Jan;140(1):49-67. doi: 10.1093/brain/aww272. Epub 2016 Nov 17.

47.

Dissociation of Early and Delayed Cerebral Infarction After Aneurysmal Subarachnoid Hemorrhage.

Ayling OG, Ibrahim GM, Alotaibi NM, Gooderham PA, Macdonald RL.

Stroke. 2016 Dec;47(12):2945-2951. Epub 2016 Nov 8.

PMID:
27827324
48.

Loss of Consciousness at Onset of Aneurysmal Subarachnoid Hemorrhage is Associated with Functional Outcomes in Good-Grade Patients.

Wang J, Alotaibi NM, Akbar MA, Ayling OG, Ibrahim GM, Macdonald RL; SAHIT collaborators.

World Neurosurg. 2017 Feb;98:308-313. doi: 10.1016/j.wneu.2016.10.099. Epub 2016 Nov 3.

PMID:
27818312
49.

Robust effects of genetic background on responses to subarachnoid hemorrhage in mice.

D'Abbondanza JA, Ai J, Lass E, Wan H, Brathwaite S, Tso MK, Lee C, Marsden PA, Macdonald RL.

J Cereb Blood Flow Metab. 2016 Nov;36(11):1942-1954. Epub 2015 Oct 26.

50.

A de novo missense mutation of GABRB2 causes early myoclonic encephalopathy.

Ishii A, Kang JQ, Schornak CC, Hernandez CC, Shen W, Watkins JC, Macdonald RL, Hirose S.

J Med Genet. 2017 Mar;54(3):202-211. doi: 10.1136/jmedgenet-2016-104083. Epub 2016 Oct 27.

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