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Items: 1 to 50 of 127

1.

The mechanism of cancer cell death by PARP inhibitors goes beyond DNA damage alone.

Macciò A, Madeddu C.

Int J Cancer. 2019 May 9. doi: 10.1002/ijc.32392. [Epub ahead of print] No abstract available.

PMID:
31070782
2.

Next generation sequencing driven successful combined treatment with laparoscopic surgery and immunotherapy for relapsed stage IVB cervical and synchronous stage IV lung cancer.

Madeddu C, Kotsonis P, Lavra F, Chiappe G, Melis L, Mura E, Scartozzi M, Macciò A.

Oncotarget. 2019 Mar 12;10(21):2012-2021. doi: 10.18632/oncotarget.26769. eCollection 2019 Mar 12.

3.

Editorial: Biological Mechanism-Based and Patient-Centered Management of Cancer-Related Symptoms and Syndromes.

Macciò A, Busquets S, Madeddu C, Argilés JM.

Front Physiol. 2018 Dec 18;9:1819. doi: 10.3389/fphys.2018.01819. eCollection 2018. No abstract available.

4.

Pathogenesis and Treatment Options of Cancer Related Anemia: Perspective for a Targeted Mechanism-Based Approach.

Madeddu C, Gramignano G, Astara G, Demontis R, Sanna E, Atzeni V, Macciò A.

Front Physiol. 2018 Sep 20;9:1294. doi: 10.3389/fphys.2018.01294. eCollection 2018. Review.

5.

Future Prospects for PD-1 Targeting, Macrophage Infiltration, and IDO Pathway Activation in Patients With Sarcomas.

Macciò A, Madeddu C.

JAMA Oncol. 2018 Aug 1;4(8):1134. doi: 10.1001/jamaoncol.2018.0875. No abstract available.

PMID:
29902292
6.

Microenvironmental M1 tumor-associated macrophage polarization influences cancer-related anemia in advanced ovarian cancer: key role of interleukin-6.

Madeddu C, Gramignano G, Kotsonis P, Coghe F, Atzeni V, Scartozzi M, Macciò A.

Haematologica. 2018 Sep;103(9):e388-e391. doi: 10.3324/haematol.2018.191551. Epub 2018 Apr 19. No abstract available.

7.

Feasibility and safety of total laparoscopic hysterectomy for huge uteri without the use of uterine manipulator: description of emblematic cases.

Macciò A, Madeddu C, Kotsonis P, Chiappe G, Lavra F, Collu I, Demontis R.

Gynecol Surg. 2018;15(1):6. doi: 10.1186/s10397-018-1037-5. Epub 2018 Feb 26.

8.

Abdominal leiomyosarcomatosis after surgery with external morcellation for occult smooth muscle tumors of uncertain malignant potential: A case report.

Macciò A, Chiappe G, Kotsonis P, Lavra F, Serra M, Demontis R, Madeddu C.

Int J Surg Case Rep. 2017;38:107-110. doi: 10.1016/j.ijscr.2017.07.020. Epub 2017 Jul 19.

9.

Laparoscopic removal of a very large uterus weighting 5320 g is feasible and safe: a case report.

Macciò A, Kotsonis P, Lavra F, Chiappe G, Sanna D, Zamboni F, Madeddu C.

BMC Surg. 2017 May 4;17(1):50. doi: 10.1186/s12893-017-0248-4.

10.

Combined laparoscopic excisional surgery for synchronous endometrial and rectal adenocarcinoma in an obese woman.

Macciò A, Lavra F, Chiappe G, Kotsonis P, Sollai G, Zamboni F, Madeddu C.

J Obstet Gynaecol. 2016 Nov;36(8):1012-1015. Epub 2016 Oct 18. No abstract available.

PMID:
27750462
11.

Long-Term Survival in a Patient With Abdominal Sarcomatosis From Uterine Leiomyosarcoma: Role of Repeated Laparoscopic Surgery in Treatment and Follow-Up.

Macciò A, Kotsonis P, Chiappe G, Melis L, Zamboni F, Madeddu C.

J Minim Invasive Gynecol. 2016 Sep-Oct;23(6):1003-8. doi: 10.1016/j.jmig.2016.05.005. Epub 2016 May 24.

PMID:
27234428
12.

Surgical outcome and complications of total laparoscopic hysterectomy for very large myomatous uteri in relation to uterine weight: a prospective study in a continuous series of 461 procedures.

Macciò A, Chiappe G, Kotsonis P, Nieddu R, Lavra F, Serra M, Onnis P, Sollai G, Zamboni F, Madeddu C.

Arch Gynecol Obstet. 2016 Sep;294(3):525-31. doi: 10.1007/s00404-016-4075-0. Epub 2016 Mar 25.

PMID:
27016346
13.

Muscle wasting as main evidence of energy impairment in cancer cachexia: future therapeutic approaches.

Madeddu C, Mantovani G, Gramignano G, Astara G, Macciò A.

Future Oncol. 2015 Oct;11(19):2697-2710. doi: 10.2217/fon.15.195. Epub 2015 Sep 17.

PMID:
26376740
14.

Advances in pharmacologic strategies for cancer cachexia.

Madeddu C, Mantovani G, Gramignano G, Macciò A.

Expert Opin Pharmacother. 2015;16(14):2163-77. doi: 10.1517/14656566.2015.1079621. Epub 2015 Sep 2. Review.

PMID:
26330024
15.

A Multitargeted Treatment Approach for Anemia and Cachexia in Metastatic Castration-Resistant Prostate Cancer.

Macciò A, Gramignano G, Madeddu C.

J Pain Symptom Manage. 2015 Aug;50(2):e1-4. doi: 10.1016/j.jpainsymman.2015.04.014. Epub 2015 May 21. No abstract available.

PMID:
26004402
16.

Mental disorders in Italian prisoners: results of the REDiMe study.

Macciò A, Meloni FR, Sisti D, Rocchi MB, Petretto DR, Masala C, Preti A.

Psychiatry Res. 2015 Feb 28;225(3):522-30. doi: 10.1016/j.psychres.2014.11.053. Epub 2014 Dec 6.

PMID:
25534756
17.

Surprising results of a supportive integrated therapy in myelofibrosis.

Macciò A, Gramignano G, Madeddu C.

Nutrition. 2015 Jan;31(1):239-43. doi: 10.1016/j.nut.2014.07.016. Epub 2014 Aug 6.

PMID:
25466670
18.

Role of inflammation and oxidative stress in post-menopausal oestrogen-dependent breast cancer.

Madeddu C, Gramignano G, Floris C, Murenu G, Sollai G, Macciò A.

J Cell Mol Med. 2014 Dec;18(12):2519-29. doi: 10.1111/jcmm.12413. Epub 2014 Oct 22.

19.

The role of inflammation, iron, and nutritional status in cancer-related anemia: results of a large, prospective, observational study.

Macciò A, Madeddu C, Gramignano G, Mulas C, Tanca L, Cherchi MC, Floris C, Omoto I, Barracca A, Ganz T.

Haematologica. 2015 Jan;100(1):124-32. doi: 10.3324/haematol.2014.112813. Epub 2014 Sep 19.

20.

Ovarian hyperstimulation in premenopausal women during adjuvant tamoxifen treatment for endocrine-dependent breast cancer: A report of two cases.

Madeddu C, Gramignano G, Kotsonis P, Paribello F, Macciò A.

Oncol Lett. 2014 Sep;8(3):1279-1282. Epub 2014 Jul 4.

21.

Large twisted ovarian fibroma associated with Meigs' syndrome, abdominal pain and severe anemia treated by laparoscopic surgery.

Macciò A, Madeddu C, Kotsonis P, Pietrangeli M, Paoletti AM.

BMC Surg. 2014 Jun 24;14:38. doi: 10.1186/1471-2482-14-38.

22.

Successful laparoscopic management of a giant ovarian cyst.

Macciò A, Madeddu C, Kotsonis P, Pietrangeli M, Paoletti AM.

J Obstet Gynaecol. 2014 Oct;34(7):651-2. doi: 10.3109/01443615.2014.902432. Epub 2014 Apr 30. No abstract available.

PMID:
24786285
23.

The role of interleukin-6 in the evolution of ovarian cancer: clinical and prognostic implications--a review.

Macciò A, Madeddu C.

J Mol Med (Berl). 2013 Dec;91(12):1355-68. doi: 10.1007/s00109-013-1080-7. Epub 2013 Sep 21. Review.

PMID:
24057813
24.

Drugs in development for treatment of patients with cancer-related anorexia and cachexia syndrome.

Mantovani G, Madeddu C, Macciò A.

Drug Des Devel Ther. 2013 Aug 12;7:645-56. doi: 10.2147/DDDT.S39771. eCollection 2013. Retraction in: Drug Des Devel Ther. 2013;7:1385.

25.

Cisplatin : an old drug with a newfound efficacy -- from mechanisms of action to cytotoxicity.

Macciò A, Madeddu C.

Expert Opin Pharmacother. 2013 Sep;14(13):1839-57. doi: 10.1517/14656566.2013.813934. Epub 2013 Jul 22. Review.

PMID:
23876094
26.

Management of anemia of inflammation in the elderly.

Macciò A, Madeddu C.

Anemia. 2012;2012:563251. doi: 10.1155/2012/563251. Epub 2012 Oct 3.

27.

Current pharmacotherapy options for cancer anorexia and cachexia.

Macciò A, Madeddu C, Mantovani G.

Expert Opin Pharmacother. 2012 Dec;13(17):2453-72. doi: 10.1517/14656566.2012.734297. Epub 2012 Oct 17. Review.

PMID:
23072481
28.

Prevalence of KRAS, BRAF, and PIK3CA somatic mutations in patients with colorectal carcinoma may vary in the same population: clues from Sardinia.

Palomba G, Colombino M, Contu A, Massidda B, Baldino G, Pazzola A, Ionta M, Capelli F, Trova V, Sedda T, Sanna G, Tanda F, Budroni M; Sardinian Translational Oncology Group (STOG), Palmieri G, Cossu A, Contu M, Cuccu A, Farris A, Macciò A, Mameli G, Olmeo N, Ortu S, Petretto E, Pusceddu V, Virdis L.

J Transl Med. 2012 Aug 29;10:178. doi: 10.1186/1479-5876-10-178.

29.

Multitargeted treatment of cancer cachexia.

Madeddu C, Maccio A, Mantovani G.

Crit Rev Oncog. 2012;17(3):305-14. Review.

PMID:
22831161
30.

Three cases of laparoscopic myomectomy performed during pregnancy for pedunculated uterine myomas.

Macciò A, Madeddu C, Kotsonis P, Caffiero A, Desogus A, Pietrangeli M, Paoletti AM.

Arch Gynecol Obstet. 2012 Nov;286(5):1209-14. doi: 10.1007/s00404-012-2441-0. Epub 2012 Jul 3.

PMID:
22752596
31.

Cachexia and oxidative stress in cancer: an innovative therapeutic management.

Mantovani G, Madeddu C, Macciò A.

Curr Pharm Des. 2012;18(31):4813-8. Review.

PMID:
22632861
32.

L-Carnitine: an adequate supplement for a multi-targeted anti-wasting therapy in cancer.

Busquets S, Serpe R, Toledo M, Betancourt A, Marmonti E, Orpí M, Pin F, Capdevila E, Madeddu C, López-Soriano FJ, Mantovani G, Macciò A, Argilés JM.

Clin Nutr. 2012 Dec;31(6):889-95. doi: 10.1016/j.clnu.2012.03.005. Epub 2012 May 19.

PMID:
22608917
33.

The epidemiology of homicide in Italy by season, day of the week and time of day.

Sisti D, Rocchi MB, Macciò A, Preti A.

Med Sci Law. 2012 Apr;52(2):100-6. doi: 10.1258/msl.2011.010147. Epub 2011 Dec 5.

PMID:
22422785
34.

Inflammation and ovarian cancer.

Macciò A, Madeddu C.

Cytokine. 2012 May;58(2):133-47. doi: 10.1016/j.cyto.2012.01.015. Epub 2012 Feb 19. Review.

PMID:
22349527
35.

Successful pregnancy following myomectomy of a giant uterine myoma: role of a combined surgical approach.

Macciò A, Madeddu C, Caffiero A, Paoletti AM.

Arch Gynecol Obstet. 2012 Jun;285(6):1577-80. doi: 10.1007/s00404-011-2197-y. Epub 2011 Dec 30.

PMID:
22207499
36.

A randomized phase III clinical trial of a combined treatment for cachexia in patients with gynecological cancers: evaluating the impact on metabolic and inflammatory profiles and quality of life.

Macciò A, Madeddu C, Gramignano G, Mulas C, Floris C, Sanna E, Cau MC, Panzone F, Mantovani G.

Gynecol Oncol. 2012 Mar;124(3):417-25. doi: 10.1016/j.ygyno.2011.12.435. Epub 2011 Dec 20.

PMID:
22198049
37.

Obesity, inflammation, and postmenopausal breast cancer: therapeutic implications.

Macciò A, Madeddu C.

ScientificWorldJournal. 2011;11:2020-36. doi: 10.1100/2011/806787. Epub 2011 Oct 27. Review.

38.

Randomized phase III clinical trial of a combined treatment with carnitine + celecoxib ± megestrol acetate for patients with cancer-related anorexia/cachexia syndrome.

Madeddu C, Dessì M, Panzone F, Serpe R, Antoni G, Cau MC, Montaldo L, Mela Q, Mura M, Astara G, Tanca FM, Macciò A, Mantovani G.

Clin Nutr. 2012 Apr;31(2):176-82. doi: 10.1016/j.clnu.2011.10.005. Epub 2011 Nov 1.

PMID:
22047681
39.

Efficacy and safety of oral lactoferrin supplementation in combination with rHuEPO-beta for the treatment of anemia in advanced cancer patients undergoing chemotherapy: open-label, randomized controlled study.

Macciò A, Madeddu C, Gramignano G, Mulas C, Sanna E, Mantovani G.

Oncologist. 2010;15(8):894-902. doi: 10.1634/theoncologist.2010-0020. Epub 2010 Jul 20.

40.

Oxytocin both increases proliferative response of peripheral blood lymphomonocytes to phytohemagglutinin and reverses immunosuppressive estrogen activity.

Macciò A, Madeddu C, Chessa P, Panzone F, Lissoni P, Mantovani G.

In Vivo. 2010 Mar-Apr;24(2):157-63.

PMID:
20363988
41.

Correlation of body mass index and leptin with tumor size and stage of disease in hormone-dependent postmenopausal breast cancer: preliminary results and therapeutic implications.

Macciò A, Madeddu C, Gramignano G, Mulas C, Floris C, Massa D, Astara G, Chessa P, Mantovani G.

J Mol Med (Berl). 2010 Jul;88(7):677-86. doi: 10.1007/s00109-010-0611-8. Epub 2010 Mar 26.

PMID:
20339829
42.

Randomized phase III clinical trial of five different arms of treatment in 332 patients with cancer cachexia.

Mantovani G, Macciò A, Madeddu C, Serpe R, Massa E, Dessì M, Panzone F, Contu P.

Oncologist. 2010;15(2):200-11. doi: 10.1634/theoncologist.2009-0153. Epub 2010 Feb 15.

43.

Phase II nonrandomized study of the efficacy and safety of COX-2 inhibitor celecoxib on patients with cancer cachexia.

Mantovani G, Macciò A, Madeddu C, Serpe R, Antoni G, Massa E, Dessì M, Panzone F.

J Mol Med (Berl). 2010 Jan;88(1):85-92. doi: 10.1007/s00109-009-0547-z. Epub 2009 Oct 3.

PMID:
19802504
44.

Use of erythropoiesis stimulating agents for the treatment of anaemia and related fatigue in a pregnant woman with HbH disease.

Macciò A, Madeddu C, Chessa P, Mantovani G, Galanello R.

Br J Haematol. 2009 Aug;146(3):335-7. doi: 10.1111/j.1365-2141.2009.07755.x. Epub 2009 May 19. No abstract available.

PMID:
19466977
45.

Adipose tissue as target organ in the treatment of hormone-dependent breast cancer: new therapeutic perspectives.

Macciò A, Madeddu C, Mantovani G.

Obes Rev. 2009 Nov;10(6):660-70. doi: 10.1111/j.1467-789X.2009.00592.x. Epub 2009 May 12. Review.

PMID:
19460113
46.

Medroxyprogesterone acetate in the management of cancer cachexia.

Madeddu C, Macciò A, Panzone F, Tanca FM, Mantovani G.

Expert Opin Pharmacother. 2009 Jun;10(8):1359-66. doi: 10.1517/14656560902960162. Review.

PMID:
19445562
47.

Carbocysteine: clinical experience and new perspectives in the treatment of chronic inflammatory diseases.

Macciò A, Madeddu C, Panzone F, Mantovani G.

Expert Opin Pharmacother. 2009 Mar;10(4):693-703. doi: 10.1517/14656560902758343 . Review.

PMID:
19239402
48.

Evidence that human serum with high levels of estrogens interferes with immune system both by decreasing CD25 expression on T-cell and by increasing interleukin-2 availability.

Macciò A, Madeddu C, Sanna E, Panzone F, Volpe A, Mantovani G.

Reprod Sci. 2008 Nov;15(9):961-9. doi: 10.1177/1933719108322428.

PMID:
19050329
49.

An Innovative Treatment Approach for Cancer-Related Anorexia/Cachexia and Oxidative Stress: Background and Design of an Ongoing, Phase III, Randomized Clinical Trial.

Mantovani G, Madeddu C, Gramignano G, Serpe R, Massa E, Deiana L, Macciò A.

Support Cancer Ther. 2007 May 1;4(3):163-7. doi: 10.3816/SCT.2007.n.011. No abstract available.

PMID:
18632483
50.

Interleukin-6 and leptin as markers of energy metabolic changes in advanced ovarian cancer patients.

Macciò A, Madeddu C, Massa D, Astara G, Farci D, Melis GB, Mantovani G.

J Cell Mol Med. 2009 Sep;13(9B):3951-9. doi: 10.1111/j.1582-4934.2008.00408.x. Epub 2008 Jun 27.

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