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Items: 15

1.

Docetaxel-trastuzumab stealth immunoliposome: development and in vitro proof of concept studies in breast cancer.

Rodallec A, Brunel JM, Giacometti S, Maccario H, Correard F, Mas E, Orneto C, Savina A, Bouquet F, Lacarelle B, Ciccolini J, Fanciullino R.

Int J Nanomedicine. 2018 Jun 18;13:3451-3465. doi: 10.2147/IJN.S162454. eCollection 2018.

2.

In Cell and In Vitro Assays to Measure PTEN Ubiquitination.

Gupta A, Maccario H, Kriplani N, Leslie NR.

Methods Mol Biol. 2016;1388:155-65. doi: 10.1007/978-1-4939-3299-3_11.

PMID:
27033076
3.

The differential effects of wild-type and mutated K-Ras on MST2 signaling are determined by K-Ras activation kinetics.

Romano D, Maccario H, Doherty C, Quinn NP, Kolch W, Matallanas D.

Mol Cell Biol. 2013 May;33(9):1859-68. doi: 10.1128/MCB.01414-12. Epub 2013 Mar 4.

4.

PTEN protein phosphatase activity correlates with control of gene expression and invasion, a tumor-suppressing phenotype, but not with AKT activity.

Tibarewal P, Zilidis G, Spinelli L, Schurch N, Maccario H, Gray A, Perera NM, Davidson L, Barton GJ, Leslie NR.

Sci Signal. 2012 Feb 28;5(213):ra18. doi: 10.1126/scisignal.2002138.

5.

Switches, excitable responses and oscillations in the Ring1B/Bmi1 ubiquitination system.

Nguyen LK, Muñoz-García J, Maccario H, Ciechanover A, Kolch W, Kholodenko BN.

PLoS Comput Biol. 2011 Dec;7(12):e1002317. doi: 10.1371/journal.pcbi.1002317. Epub 2011 Dec 15.

6.

Ubiquitination of PTEN (phosphatase and tensin homolog) inhibits phosphatase activity and is enhanced by membrane targeting and hyperosmotic stress.

Maccario H, Perera NM, Gray A, Downes CP, Leslie NR.

J Biol Chem. 2010 Apr 23;285(17):12620-8. doi: 10.1074/jbc.M109.072280. Epub 2010 Feb 22.

7.

Suppression of cellular proliferation and invasion by the concerted lipid and protein phosphatase activities of PTEN.

Davidson L, Maccario H, Perera NM, Yang X, Spinelli L, Tibarewal P, Glancy B, Gray A, Weijer CJ, Downes CP, Leslie NR.

Oncogene. 2010 Feb 4;29(5):687-97. doi: 10.1038/onc.2009.384. Epub 2009 Nov 16.

8.

Indirect mechanisms of carcinogenesis via downregulation of PTEN function.

Leslie NR, Spinelli L, Tibarewal P, Zilidis G, Weerasinghe N, Lim JC, Maccario H, Downes CP.

Adv Enzyme Regul. 2010;50(1):112-8. doi: 10.1016/j.advenzreg.2009.10.015. Epub 2009 Nov 4. Review. No abstract available.

PMID:
19895830
9.

The significance of PTEN's protein phosphatase activity.

Leslie NR, Maccario H, Spinelli L, Davidson L.

Adv Enzyme Regul. 2009;49(1):190-6. doi: 10.1016/j.advenzreg.2008.12.002. Epub 2008 Dec 31. Review. No abstract available.

PMID:
19168090
10.

Ubiquitination as a priming process of PKC alpha and PKC epsilon degradation in the alphaT3-1 gonadotrope cell line.

Poulin B, Maccario H, Thirion S, Junoy B, Boyer B, Enjalbert A, Drouva SV.

Neuroendocrinology. 2009;89(3):252-66. doi: 10.1159/000164694. Epub 2008 Oct 16.

PMID:
18931473
11.

Understanding PTEN regulation: PIP2, polarity and protein stability.

Leslie NR, Batty IH, Maccario H, Davidson L, Downes CP.

Oncogene. 2008 Sep 18;27(41):5464-76. doi: 10.1038/onc.2008.243. Review.

PMID:
18794881
12.

PTEN is destabilized by phosphorylation on Thr366.

Maccario H, Perera NM, Davidson L, Downes CP, Leslie NR.

Biochem J. 2007 Aug 1;405(3):439-44.

13.

Stimulation of PI 3-kinase signaling via inhibition of the tumor suppressor phosphatase, PTEN.

Downes CP, Ross S, Maccario H, Perera N, Davidson L, Leslie NR.

Adv Enzyme Regul. 2007;47:184-94. Epub 2006 Dec 30. Review. No abstract available.

PMID:
17343901
14.

Protein kinase Cdelta as gonadotropin-releasing hormone target isoenzyme in the alphaT3-1 gonadotrope cell line.

Maccario H, Junoy B, Poulin B, Boyer B, Enjalbert A, Drouva SV.

Neuroendocrinology. 2004;79(4):204-20. Epub 2004 May 18.

PMID:
15153754
15.

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