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Items: 50

1.

Spatially resolved transcriptomics reveals plant host responses to pathogens.

Giolai M, Verweij W, Lister A, Heavens D, Macaulay I, Clark MD.

Plant Methods. 2019 Oct 10;15:114. doi: 10.1186/s13007-019-0498-5. eCollection 2019.

2.

A critical comparison of technologies for a plant genome sequencing project.

Paajanen P, Kettleborough G, López-Girona E, Giolai M, Heavens D, Baker D, Lister A, Cugliandolo F, Wilde G, Hein I, Macaulay I, Bryan GJ, Clark MD.

Gigascience. 2019 Mar 1;8(3). pii: giy163. doi: 10.1093/gigascience/giy163.

3.

Acute myeloid leukemia induces protumoral p16INK4a-driven senescence in the bone marrow microenvironment.

Abdul-Aziz AM, Sun Y, Hellmich C, Marlein CR, Mistry J, Forde E, Piddock RE, Shafat MS, Morfakis A, Mehta T, Di Palma F, Macaulay I, Ingham CJ, Haestier A, Collins A, Campisi J, Bowles KM, Rushworth SA.

Blood. 2019 Jan 31;133(5):446-456. doi: 10.1182/blood-2018-04-845420. Epub 2018 Nov 6.

PMID:
30401703
4.

SRSF3 maintains transcriptome integrity in oocytes by regulation of alternative splicing and transposable elements.

Do DV, Strauss B, Cukuroglu E, Macaulay I, Wee KB, Hu TX, Igor RLM, Lee C, Harrison A, Butler R, Dietmann S, Jernej U, Marioni J, Smith CWJ, Göke J, Surani MA.

Cell Discov. 2018 Jun 19;4:33. doi: 10.1038/s41421-018-0032-3. eCollection 2018.

5.

Defining Cell Identity with Single-Cell Omics.

Mincarelli L, Lister A, Lipscombe J, Macaulay IC.

Proteomics. 2018 Sep;18(18):e1700312. doi: 10.1002/pmic.201700312. Epub 2018 May 28. Review.

6.

Erratum: Pluripotent state transitions coordinate morphogenesis in mouse and human embryos.

Shahbazi MN, Scialdone A, Skorupska N, Weberling A, Recher G, Zhu M, Jedrusik A, Devito LG, Noli L, Macaulay IC, Buecker C, Khalaf Y, Ilic D, Voet T, Marioni JC, Zernicka-Goetz M.

Nature. 2018 Feb 28;555(7694):126. doi: 10.1038/nature25995.

PMID:
29493594
7.

Pluripotent state transitions coordinate morphogenesis in mouse and human embryos.

Shahbazi MN, Scialdone A, Skorupska N, Weberling A, Recher G, Zhu M, Jedrusik A, Devito LG, Noli L, Macaulay IC, Buecker C, Khalaf Y, Ilic D, Voet T, Marioni JC, Zernicka-Goetz M.

Nature. 2017 Dec 14;552(7684):239-243. doi: 10.1038/nature24675. Epub 2017 Nov 29. Erratum in: Nature. 2018 Feb 28;555(7694):126.

8.

Single-Cell Landscape of Transcriptional Heterogeneity and Cell Fate Decisions during Mouse Early Gastrulation.

Mohammed H, Hernando-Herraez I, Savino A, Scialdone A, Macaulay I, Mulas C, Chandra T, Voet T, Dean W, Nichols J, Marioni JC, Reik W.

Cell Rep. 2017 Aug 1;20(5):1215-1228. doi: 10.1016/j.celrep.2017.07.009.

9.

Proliferation Drives Aging-Related Functional Decline in a Subpopulation of the Hematopoietic Stem Cell Compartment.

Kirschner K, Chandra T, Kiselev V, Flores-Santa Cruz D, Macaulay IC, Park HJ, Li J, Kent DG, Kumar R, Pask DC, Hamilton TL, Hemberg M, Reik W, Green AR.

Cell Rep. 2017 May 23;19(8):1503-1511. doi: 10.1016/j.celrep.2017.04.074.

10.

Power analysis of single-cell RNA-sequencing experiments.

Svensson V, Natarajan KN, Ly LH, Miragaia RJ, Labalette C, Macaulay IC, Cvejic A, Teichmann SA.

Nat Methods. 2017 Apr;14(4):381-387. doi: 10.1038/nmeth.4220. Epub 2017 Mar 6.

11.

Single-Cell Multiomics: Multiple Measurements from Single Cells.

Macaulay IC, Ponting CP, Voet T.

Trends Genet. 2017 Feb;33(2):155-168. doi: 10.1016/j.tig.2016.12.003. Epub 2017 Jan 13. Review.

12.

Single-cell transcriptome analysis of fish immune cells provides insight into the evolution of vertebrate immune cell types.

Carmona SJ, Teichmann SA, Ferreira L, Macaulay IC, Stubbington MJ, Cvejic A, Gfeller D.

Genome Res. 2017 Mar;27(3):451-461. doi: 10.1101/gr.207704.116. Epub 2017 Jan 13.

13.

Genome-wide in vivo screen identifies novel host regulators of metastatic colonization.

van der Weyden L, Arends MJ, Campbell AD, Bald T, Wardle-Jones H, Griggs N, Velasco-Herrera MD, Tüting T, Sansom OJ, Karp NA, Clare S, Gleeson D, Ryder E, Galli A, Tuck E, Cambridge EL, Voet T, Macaulay IC, Wong K; Sanger Mouse Genetics Project, Spiegel S, Speak AO, Adams DJ.

Nature. 2017 Jan 12;541(7636):233-236. doi: 10.1038/nature20792. Epub 2017 Jan 4.

14.

Initial seeding of the embryonic thymus by immune-restricted lympho-myeloid progenitors.

Luis TC, Luc S, Mizukami T, Boukarabila H, Thongjuea S, Woll PS, Azzoni E, Giustacchini A, Lutteropp M, Bouriez-Jones T, Vaidya H, Mead AJ, Atkinson D, Böiers C, Carrelha J, Macaulay IC, Patient R, Geissmann F, Nerlov C, Sandberg R, de Bruijn MFTR, Blackburn CC, Godin I, Jacobsen SEW.

Nat Immunol. 2016 Dec;17(12):1424-1435. doi: 10.1038/ni.3576. Epub 2016 Oct 3.

15.

Separation and parallel sequencing of the genomes and transcriptomes of single cells using G&T-seq.

Macaulay IC, Teng MJ, Haerty W, Kumar P, Ponting CP, Voet T.

Nat Protoc. 2016 Nov;11(11):2081-103. doi: 10.1038/nprot.2016.138. Epub 2016 Sep 29.

PMID:
27685099
16.

Resolving early mesoderm diversification through single-cell expression profiling.

Scialdone A, Tanaka Y, Jawaid W, Moignard V, Wilson NK, Macaulay IC, Marioni JC, Göttgens B.

Nature. 2016 Jul 14;535(7611):289-293. doi: 10.1038/nature18633. Epub 2016 Jul 6.

17.

Heterogeneity in Oct4 and Sox2 Targets Biases Cell Fate in 4-Cell Mouse Embryos.

Goolam M, Scialdone A, Graham SJL, Macaulay IC, Jedrusik A, Hupalowska A, Voet T, Marioni JC, Zernicka-Goetz M.

Cell. 2016 Mar 24;165(1):61-74. doi: 10.1016/j.cell.2016.01.047.

18.

Single-cell RNA sequencing reveals molecular and functional platelet bias of aged haematopoietic stem cells.

Grover A, Sanjuan-Pla A, Thongjuea S, Carrelha J, Giustacchini A, Gambardella A, Macaulay I, Mancini E, Luis TC, Mead A, Jacobsen SE, Nerlov C.

Nat Commun. 2016 Mar 24;7:11075. doi: 10.1038/ncomms11075.

19.

Single-Cell RNA-Sequencing Reveals a Continuous Spectrum of Differentiation in Hematopoietic Cells.

Macaulay IC, Svensson V, Labalette C, Ferreira L, Hamey F, Voet T, Teichmann SA, Cvejic A.

Cell Rep. 2016 Feb 2;14(4):966-977. doi: 10.1016/j.celrep.2015.12.082. Epub 2016 Jan 21.

20.

Parallel single-cell sequencing links transcriptional and epigenetic heterogeneity.

Angermueller C, Clark SJ, Lee HJ, Macaulay IC, Teng MJ, Hu TX, Krueger F, Smallwood S, Ponting CP, Voet T, Kelsey G, Stegle O, Reik W.

Nat Methods. 2016 Mar;13(3):229-232. doi: 10.1038/nmeth.3728. Epub 2016 Jan 11.

21.

Dynamic spatio-temporal contribution of single β5t+ cortical epithelial precursors to the thymus medulla.

Mayer CE, Žuklys S, Zhanybekova S, Ohigashi I, Teh HY, Sansom SN, Shikama-Dorn N, Hafen K, Macaulay IC, Deadman ME, Ponting CP, Takahama Y, Holländer GA.

Eur J Immunol. 2016 Apr;46(4):846-56. doi: 10.1002/eji.201545995. Epub 2016 Jan 18.

22.

Integrin Based Isolation Enables Purification of Murine Lineage Committed Cardiomyocytes.

Tarnawski L, Xian X, Monnerat G, Macaulay IC, Malan D, Borgman A, Wu SM, Fleischmann BK, Jovinge S.

PLoS One. 2015 Aug 31;10(8):e0135880. doi: 10.1371/journal.pone.0135880. eCollection 2015.

23.

Combined Single-Cell Functional and Gene Expression Analysis Resolves Heterogeneity within Stem Cell Populations.

Wilson NK, Kent DG, Buettner F, Shehata M, Macaulay IC, Calero-Nieto FJ, Sánchez Castillo M, Oedekoven CA, Diamanti E, Schulte R, Ponting CP, Voet T, Caldas C, Stingl J, Green AR, Theis FJ, Göttgens B.

Cell Stem Cell. 2015 Jun 4;16(6):712-24. doi: 10.1016/j.stem.2015.04.004. Epub 2015 May 21.

24.

PDGFRα demarcates the cardiogenic clonogenic Sca1+ stem/progenitor cell in adult murine myocardium.

Noseda M, Harada M, McSweeney S, Leja T, Belian E, Stuckey DJ, Abreu Paiva MS, Habib J, Macaulay I, de Smith AJ, al-Beidh F, Sampson R, Lumbers RT, Rao P, Harding SE, Blakemore AI, Jacobsen SE, Barahona M, Schneider MD.

Nat Commun. 2015 May 18;6:6930. doi: 10.1038/ncomms7930.

25.

G&T-seq: parallel sequencing of single-cell genomes and transcriptomes.

Macaulay IC, Haerty W, Kumar P, Li YI, Hu TX, Teng MJ, Goolam M, Saurat N, Coupland P, Shirley LM, Smith M, Van der Aa N, Banerjee R, Ellis PD, Quail MA, Swerdlow HP, Zernicka-Goetz M, Livesey FJ, Ponting CP, Voet T.

Nat Methods. 2015 Jun;12(6):519-22. doi: 10.1038/nmeth.3370. Epub 2015 Apr 27.

PMID:
25915121
26.

Decoding the regulatory network of early blood development from single-cell gene expression measurements.

Moignard V, Woodhouse S, Haghverdi L, Lilly AJ, Tanaka Y, Wilkinson AC, Buettner F, Macaulay IC, Jawaid W, Diamanti E, Nishikawa SI, Piterman N, Kouskoff V, Theis FJ, Fisher J, Göttgens B.

Nat Biotechnol. 2015 Mar;33(3):269-276. doi: 10.1038/nbt.3154. Epub 2015 Feb 9.

27.

Transcriptional diversity during lineage commitment of human blood progenitors.

Chen L, Kostadima M, Martens JHA, Canu G, Garcia SP, Turro E, Downes K, Macaulay IC, Bielczyk-Maczynska E, Coe S, Farrow S, Poudel P, Burden F, Jansen SBG, Astle WJ, Attwood A, Bariana T, de Bono B, Breschi A, Chambers JC, Consortium B, Choudry FA, Clarke L, Coupland P, van der Ent M, Erber WN, Jansen JH, Favier R, Fenech ME, Foad N, Freson K, van Geet C, Gomez K, Guigo R, Hampshire D, Kelly AM, Kerstens HHD, Kooner JS, Laffan M, Lentaigne C, Labalette C, Martin T, Meacham S, Mumford A, Nürnberg S, Palumbo E, van der Reijden BA, Richardson D, Sammut SJ, Slodkowicz G, Tamuri AU, Vasquez L, Voss K, Watt S, Westbury S, Flicek P, Loos R, Goldman N, Bertone P, Read RJ, Richardson S, Cvejic A, Soranzo N, Ouwehand WH, Stunnenberg HG, Frontini M, Rendon A.

Science. 2014 Sep 26;345(6204):1251033. doi: 10.1126/science.1251033.

28.

Population and single-cell genomics reveal the Aire dependency, relief from Polycomb silencing, and distribution of self-antigen expression in thymic epithelia.

Sansom SN, Shikama-Dorn N, Zhanybekova S, Nusspaumer G, Macaulay IC, Deadman ME, Heger A, Ponting CP, Holländer GA.

Genome Res. 2014 Dec;24(12):1918-31. doi: 10.1101/gr.171645.113. Epub 2014 Sep 15.

29.

Myelodysplastic syndromes are propagated by rare and distinct human cancer stem cells in vivo.

Woll PS, Kjällquist U, Chowdhury O, Doolittle H, Wedge DC, Thongjuea S, Erlandsson R, Ngara M, Anderson K, Deng Q, Mead AJ, Stenson L, Giustacchini A, Duarte S, Giannoulatou E, Taylor S, Karimi M, Scharenberg C, Mortera-Blanco T, Macaulay IC, Clark SA, Dybedal I, Josefsen D, Fenaux P, Hokland P, Holm MS, Cazzola M, Malcovati L, Tauro S, Bowen D, Boultwood J, Pellagatti A, Pimanda JE, Unnikrishnan A, Vyas P, Göhring G, Schlegelberger B, Tobiasson M, Kvalheim G, Constantinescu SN, Nerlov C, Nilsson L, Campbell PJ, Sandberg R, Papaemmanuil E, Hellström-Lindberg E, Linnarsson S, Jacobsen SE.

Cancer Cell. 2014 Jun 16;25(6):794-808. doi: 10.1016/j.ccr.2014.03.036. Epub 2014 May 15. Erratum in: Cancer Cell. 2014 Jun 16;25(6):861. Cancer Cell. 2015 Apr 13;27(4):603-5.

30.

Computer-aided pattern recognition of large reptiles as a noninvasive application to identify individuals.

Moro D, MacAulay I.

J Appl Anim Welf Sci. 2014;17(2):125-35. doi: 10.1080/10888705.2014.883925.

PMID:
24665952
31.

Single cell genomics: advances and future perspectives.

Macaulay IC, Voet T.

PLoS Genet. 2014 Jan 30;10(1):e1004126. doi: 10.1371/journal.pgen.1004126. eCollection 2014 Jan. Review.

32.

Lymphomyeloid contribution of an immune-restricted progenitor emerging prior to definitive hematopoietic stem cells.

Böiers C, Carrelha J, Lutteropp M, Luc S, Green JC, Azzoni E, Woll PS, Mead AJ, Hultquist A, Swiers G, Perdiguero EG, Macaulay IC, Melchiori L, Luis TC, Kharazi S, Bouriez-Jones T, Deng Q, Pontén A, Atkinson D, Jensen CT, Sitnicka E, Geissmann F, Godin I, Sandberg R, de Bruijn MF, Jacobsen SE.

Cell Stem Cell. 2013 Nov 7;13(5):535-48. doi: 10.1016/j.stem.2013.08.012. Epub 2013 Sep 19.

33.

Platelet-biased stem cells reside at the apex of the haematopoietic stem-cell hierarchy.

Sanjuan-Pla A, Macaulay IC, Jensen CT, Woll PS, Luis TC, Mead A, Moore S, Carella C, Matsuoka S, Bouriez Jones T, Chowdhury O, Stenson L, Lutteropp M, Green JC, Facchini R, Boukarabila H, Grover A, Gambardella A, Thongjuea S, Carrelha J, Tarrant P, Atkinson D, Clark SA, Nerlov C, Jacobsen SE.

Nature. 2013 Oct 10;502(7470):232-6. doi: 10.1038/nature12495. Epub 2013 Aug 11.

PMID:
23934107
34.

FLT3-ITDs instruct a myeloid differentiation and transformation bias in lymphomyeloid multipotent progenitors.

Mead AJ, Kharazi S, Atkinson D, Macaulay I, Pecquet C, Loughran S, Lutteropp M, Woll P, Chowdhury O, Luc S, Buza-Vidas N, Ferry H, Clark SA, Goardon N, Vyas P, Constantinescu SN, Sitnicka E, Nerlov C, Jacobsen SE.

Cell Rep. 2013 Jun 27;3(6):1766-76. doi: 10.1016/j.celrep.2013.04.031. Epub 2013 May 30.

35.

Characterization of transcriptional networks in blood stem and progenitor cells using high-throughput single-cell gene expression analysis.

Moignard V, Macaulay IC, Swiers G, Buettner F, Schütte J, Calero-Nieto FJ, Kinston S, Joshi A, Hannah R, Theis FJ, Jacobsen SE, de Bruijn MF, Göttgens B.

Nat Cell Biol. 2013 Apr;15(4):363-72. doi: 10.1038/ncb2709. Epub 2013 Mar 24. Erratum in: Nat Cell Biol. 2013 May;15(5):544.

36.

Canonical Wnt signaling in megakaryocytes regulates proplatelet formation.

Macaulay IC, Thon JN, Tijssen MR, Steele BM, MacDonald BT, Meade G, Burns P, Rendon A, Salunkhe V, Murphy RP, Bennett C, Watkins NA, He X, Fitzgerald DJ, Italiano JE Jr, Maguire PB.

Blood. 2013 Jan 3;121(1):188-96. doi: 10.1182/blood-2012-03-416875. Epub 2012 Nov 16.

37.

The earliest thymic T cell progenitors sustain B cell and myeloid lineage potential.

Luc S, Luis TC, Boukarabila H, Macaulay IC, Buza-Vidas N, Bouriez-Jones T, Lutteropp M, Woll PS, Loughran SJ, Mead AJ, Hultquist A, Brown J, Mizukami T, Matsuoka S, Ferry H, Anderson K, Duarte S, Atkinson D, Soneji S, Domanski A, Farley A, Sanjuan-Pla A, Carella C, Patient R, de Bruijn M, Enver T, Nerlov C, Blackburn C, Godin I, Jacobsen SE.

Nat Immunol. 2012 Feb 19;13(4):412-9. doi: 10.1038/ni.2255.

38.

Transcription profiling in human platelets reveals LRRFIP1 as a novel protein regulating platelet function.

Goodall AH, Burns P, Salles I, Macaulay IC, Jones CI, Ardissino D, de Bono B, Bray SL, Deckmyn H, Dudbridge F, Fitzgerald DJ, Garner SF, Gusnanto A, Koch K, Langford C, O'Connor MN, Rice CM, Stemple D, Stephens J, Trip MD, Zwaginga JJ, Samani NJ, Watkins NA, Maguire PB, Ouwehand WH; Bloodomics Consortium.

Blood. 2010 Nov 25;116(22):4646-56. doi: 10.1182/blood-2010-04-280925. Epub 2010 Sep 10.

39.

Canonical Wnt signaling negatively regulates platelet function.

Steele BM, Harper MT, Macaulay IC, Morrell CN, Perez-Tamayo A, Foy M, Habas R, Poole AW, Fitzgerald DJ, Maguire PB.

Proc Natl Acad Sci U S A. 2009 Nov 24;106(47):19836-41. doi: 10.1073/pnas.0906268106. Epub 2009 Nov 9.

40.

A HaemAtlas: characterizing gene expression in differentiated human blood cells.

Watkins NA, Gusnanto A, de Bono B, De S, Miranda-Saavedra D, Hardie DL, Angenent WG, Attwood AP, Ellis PD, Erber W, Foad NS, Garner SF, Isacke CM, Jolley J, Koch K, Macaulay IC, Morley SL, Rendon A, Rice KM, Taylor N, Thijssen-Timmer DC, Tijssen MR, van der Schoot CE, Wernisch L, Winzer T, Dudbridge F, Buckley CD, Langford CF, Teichmann S, Göttgens B, Ouwehand WH; Bloodomics Consortium.

Blood. 2009 May 7;113(19):e1-9. doi: 10.1182/blood-2008-06-162958. Epub 2009 Feb 19.

41.

Functional genomics in zebrafish permits rapid characterization of novel platelet membrane proteins.

O'Connor MN, Salles II, Cvejic A, Watkins NA, Walker A, Garner SF, Jones CI, Macaulay IC, Steward M, Zwaginga JJ, Bray SL, Dudbridge F, de Bono B, Goodall AH, Deckmyn H, Stemple DL, Ouwehand WH; Bloodomics Consortium.

Blood. 2009 May 7;113(19):4754-62. doi: 10.1182/blood-2008-06-162693. Epub 2008 Dec 24.

42.

Identification of variation in the platelet transcriptome associated with glycoprotein 6 haplotype.

Burns P, Gusnanto A, Macaulay IC, Rankin A, Tom B, Langford CF, Dudbridge F, Ouwehand WH, Watkins NA; Bloodomics Consortium.

Platelets. 2008 Jun;19(4):258-67. doi: 10.1080/09537100801947434.

PMID:
18569861
43.

Improving the power to detect differentially expressed genes in comparative microarray experiments by including information from self-self hybridizations.

Gusnanto A, Tom B, Burns P, Macaulay I, Thijssen-Timmer DC, Tijssen MR, Langford C, Watkins N, Ouwehand W, Berzuini C, Dudbridge F.

Comput Biol Chem. 2007 Jun;31(3):178-85. Epub 2007 Mar 24.

PMID:
17499550
44.

The novel inhibitory receptor G6B is expressed on the surface of platelets and attenuates platelet function in vitro.

Newland SA, Macaulay IC, Floto AR, de Vet EC, Ouwehand WH, Watkins NA, Lyons PA, Campbell DR.

Blood. 2007 Jun 1;109(11):4806-9. Epub 2007 Feb 20.

PMID:
17311996
45.

Comparative gene expression profiling of in vitro differentiated megakaryocytes and erythroblasts identifies novel activatory and inhibitory platelet membrane proteins.

Macaulay IC, Tijssen MR, Thijssen-Timmer DC, Gusnanto A, Steward M, Burns P, Langford CF, Ellis PD, Dudbridge F, Zwaginga JJ, Watkins NA, van der Schoot CE, Ouwehand WH.

Blood. 2007 Apr 15;109(8):3260-9. Epub 2006 Dec 27.

46.

Platelet genomics and proteomics in human health and disease.

Macaulay IC, Carr P, Gusnanto A, Ouwehand WH, Fitzgerald D, Watkins NA.

J Clin Invest. 2005 Dec;115(12):3370-7. Review.

47.

Analysing the platelet transcriptome.

Macaulay IC, Carr P, Farrugia R, Watkins NA.

Vox Sang. 2004 Jul;87 Suppl 2:42-6. Review.

PMID:
15209877
48.

Pall filter debate.

Macaulay I, Keleher M.

Prof Nurse. 1993 Jul;8(10):655. No abstract available.

PMID:
8327526
49.

Management of a complex diving accident.

Norman JN, Childs CM, Jones C, Smith JA, Ross J, Riddle G, MacKintosh A, McKie NI, Macaulay II, Fructus X.

Undersea Biomed Res. 1979 Jun;6(2):209-16.

PMID:
531999
50.

PLATELET-AGGREGATION BY PHOSPHOLIPIDS AND FREE FATTY ACIDS.

KERR JW, MACAULAY I, PIRRIE R, BRONTE-STEWART B.

Lancet. 1965 Jun 19;1(7399):1296-9. No abstract available.

PMID:
14299114

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